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0.4799957 459.3600006 cm /Im13 Do Q q 20.1600037 0 0 25.9199982 0.4799957 390.2400055 cm /Im14 Do Q q 12.4799957 0 0 14.3999939 0.4799957 351.8399963 cm /Im15 Do Q q 12.9600067 0 0 41.2799988 0 290.3999939 cm /Im16 Do Q q 12.4799957 0 0 14.3999939 10.0800018 263.5200043 cm /Im17 Do Q q 10.0800018 0 0 18.2400055 0 213.6000061 cm /Im18 Do Q q 22.5599976 0 0 158.3999939 0 27.3600006 cm /Im19 Do Q q 13.4400024 0 0 13.4400024 555.3600006 26.3999939 cm /Im20 Do Q BT 0.286 0.286 0.278 rg /T1_0 1 Tf -0.035 Tc 3 Tr 10.2049 0 0 11.1 60.42 778.8 Tm (254 )Tj 0.05 Tc 8.4536 0 0 7.9001 182.92 778.8 Tm (N. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 8.9729 0 0 7.9001 196.36 778.8 Tm (NOVISKl, )Tj EMC ET BT 0.361 0.361 0.357 rg /T1_0 1 Tf 8.0255 0 0 7.9001 243.32 778.8 Tm (E. )Tj ET BT /Suspect <>BDC 0.286 0.286 0.278 rg /T1_0 1 Tf 8.5768 0 0 7.9001 255.8 778.8 Tm (BAR-YISHA )Tj EMC /Suspect <>BDC 8.5151 0 0 7.9001 307.66 778.8 Tm (Y, )Tj EMC ET BT 0.22 0.22 0.212 rg /T1_1 1 Tf 8.7408 0 0 6.8001 321.36 778.8 Tm (I. )Tj ET BT /Suspect <>BDC 0.361 0.361 0.357 rg /T1_0 1 Tf 8.763 0 0 7.9001 331.59 778.8 Tm (GU)Tj 0.22 0.22 0.212 rg 8.9655 0 0 7.9001 346.04 778.8 Tm (R, )Tj EMC /Suspect <>BDC 0.286 0.286 0.278 rg 8.1807 0 0 7.9001 359.37 778.8 Tm (S. )Tj EMC /Suspect <>BDC 8.5356 0 0 7.9001 371.43 778.8 Tm (GODFREY )Tj EMC ET BT 0.157 0.157 0.153 rg /T1_1 1 Tf 0.0076 Tc 9.1 0 0 9.1 59.94 754.33 Tm (Ta)Tj 0.286 0.286 0.278 rg 0.0083 Tc 1.148 0 Td (ble )Tj -0.035 Tc 8.7844 0 0 9.1 85.64 754.33 Tm (1. )Tj 0.0232 Tc 9.1 0 0 9.1 95.92 754.33 Tm (-Patient )Tj 0.0128 Tc 3.902 0 Td (data )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0306 Tc 8.7 0 0 8.7 59.84 732.73 Tm (Subject )Tj EMC /Suspect <>BDC 0.0126 Tc 9.876 0 Td (Sex )Tj EMC ET BT /T1_0 1 Tf 0.0256 Tc 8.7 0 0 8.7 231.3431 732.2428 Tm (Age )Tj 0.0322 Tc 9.156 0.056 Td (Height )Tj 0.0313 Tc 9.325 0 Td (Weight )Tj 0.0251 Tc 9.875 -0.056 Td (Regular )Tj 0.05 Tc 9.2761 0 0 8.7 232.79 721.68 Tm (yr )Tj 0.0135 Tc 8.7 0 0 8.7 315.75 721.68 Tm (em )Tj 0.22 0.22 0.212 rg -0.006 Tc 9.829 0 Td (kg )Tj 0.0271 Tc 8.325 -0.054 Td (Treatment )Tj 0.286 0.286 0.278 rg 0 Tc -47.53 -2.483 Td (1 )Tj /T1_1 1 Tf 9.4 0 0 9.4 145.24 699.61 Tm (M )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0078 Tc 8.7 0 0 8.7 231.54 699.61 Tm (10.5 )Tj EMC /Suspect <>BDC 0.0029 Tc 9.766 0 Td (140 )Tj EMC /Suspect <>BDC 0.03 Tc 9.733 0 Td (30 )Tj EMC /Suspect <>BDC 0.0299 Tc 9.825 0 Td (ISB )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.7 0 0 8.7 59.4714 689.0482 Tm (2 )Tj /T1_1 1 Tf 9.1 0 0 9.1 145.72 688.56 Tm (M )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0106 Tc 8.7 0 0 8.7 231.54 689.05 Tm (14.0 )Tj EMC ET BT /T1_0 1 Tf 0.0305 Tc 8.7 0 0 8.7 316.017 688.5628 Tm (165 )Tj 0.22 0.22 0.212 rg 0.0084 Tc 9.74 0.056 Td (41 )Tj ET BT /Suspect <>BDC 0.286 0.286 0.278 rg /T1_0 1 Tf 0.0299 Tc 8.7 0 0 8.7 486.6588 688.5628 Tm (ISB )Tj EMC ET BT 0.361 0.361 0.357 rg /T1_0 1 Tf 0 Tc 9.8 0 0 9.8 59.41 677.53 Tm (3 )Tj 0.286 0.286 0.278 rg /T1_1 1 Tf 9.4 0 0 9.4 145.24 677.53 Tm (M )Tj /T1_0 1 Tf 0.0106 Tc 8.7 0 0 8.7 231.06 678 Tm (14.5 )Tj 0.0029 Tc 9.766 -0.054 Td (165 )Tj 0.0273 Tc 9.786 0.054 Td (59 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0299 Tc 8.7 0 0 8.7 486.666 677.5302 Tm (ISB )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.7 0 0 8.7 59.4873 666.9684 Tm (4 )Tj /T1_1 1 Tf 9.1 0 0 9.1 145.72 666.97 Tm (M )Tj /T1_0 1 Tf 0.0106 Tc 8.7 0 0 8.7 231.06 666.97 Tm (12.5 )Tj 0.0305 Tc 9.766 0 Td (154 )Tj ET BT /Suspect <>BDC 0.22 0.22 0.212 rg /T1_0 1 Tf 0.05 Tc 8.8142 0 0 8.7 401.24 666.97 Tm (40 )Tj EMC /Suspect <>BDC 0.286 0.286 0.278 rg 9.0425 0 0 8.7 486.66 666.97 Tm (ISB.BDP )Tj EMC ET BT /T1_2 1 Tf 0 Tc 8.8 0 0 8.8 59.43 655.92 Tm (5 )Tj /T1_1 1 Tf 9.1 0 0 9.1 145.72 655.92 Tm (M )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0106 Tc 8.7 0 0 8.7 231.54 655.92 Tm (16.0 )Tj EMC ET BT /T1_0 1 Tf -0.0246 Tc 8.7 0 0 8.7 316.5042 655.92 Tm (165 )Tj 0.0476 Tc 9.3 0 0 9.3 400.76 655.92 Tm (44 )Tj ET BT /Suspect <>BDC 0.22 0.22 0.212 rg /T1_0 1 Tf 0.0299 Tc 8.7 0 0 8.7 486.66 655.92 Tm (ISB )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.7 0 0 8.7 59.8902 644.8884 Tm (6 )Tj 9 0 0 9 145.88 644.89 Tm (F )Tj ET BT /Suspect <>BDC 0.286 0.286 0.278 rg /T1_0 1 Tf 0.029 Tc 8.7 0 0 8.7 231.06 644.89 Tm (10.0 )Tj EMC ET BT /T1_0 1 Tf 0.0305 Tc 8.7 0 0 8.7 316.0242 645.3598 Tm (136 )Tj 0.03 Tc 9.789 0 Td (32 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0299 Tc 8.7 0 0 8.7 486.666 644.89 Tm (ISB )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.7 0 0 8.7 59.9136 634.3282 Tm (7 )Tj 9 0 0 9 145.4 633.85 Tm (F )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.029 Tc 8.7 0 0 8.7 231.06 634.33 Tm (17.0 )Tj EMC /Suspect <>BDC 0.0305 Tc 9.766 0 Td (170 )Tj EMC /Suspect <>BDC 0.05 Tc 8.8941 0 0 8.7 401.17 634.33 Tm (60 )Tj EMC /Suspect <>BDC 0.0299 Tc 8.7 0 0 8.7 486.66 634.33 Tm (ISB )Tj EMC ET BT /T1_0 1 Tf 0 Tc 9.1 0 0 9.1 59.84 623.29 Tm (8 )Tj 9 0 0 9 145.88 623.29 Tm (F )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.029 Tc 8.7 0 0 8.7 231.06 623.76 Tm (14.0 )Tj EMC ET BT /T1_0 1 Tf 0.0305 Tc 8.7 0 0 8.7 316.0242 623.76 Tm (147 )Tj 0.05 Tc 9.0021 0 0 9 401.18 623.76 Tm (34 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0299 Tc 8.7 0 0 8.7 486.66 623.76 Tm (ISB )Tj EMC /Suspect <>BDC 0.0379 Tc -49.159 -2.538 Td (ISB: )Tj EMC ET BT /T1_0 1 Tf 0.0242 Tc 8.7 0 0 8.7 78.1776 601.6794 Tm (Intermittent )Tj 0.0265 Tc 5.179 0 Td (sympathomjmetic )Tj 0.0128 Tc 7.794 0 Td (bronchodilators; )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 8.7817 0 0 8.7 251.96 601.68 Tm (BDP)Tj 0.157 0.157 0.153 rg 0 Tc 8.7 0 0 8.7 270.02 601.68 Tm (: )Tj EMC ET BT 0.286 0.286 0.278 rg /T1_0 1 Tf 0.0244 Tc 8.7 0 0 8.7 274.0394 601.68 Tm (Beclomethasone )Tj 0.0257 Tc 7.113 0 Td (diproprionate )Tj 0.0078 Tc 9.9 0 0 9.9 58.93 575.76 Tm (every )Tj -0.035 Tc 9.1317 0 0 9.9 87.04 575.76 Tm (15 )Tj 0.361 0.361 0.357 rg -0.0319 Tc 9.9 0 0 9.9 100.18 575.76 Tm (s. )Tj 0.286 0.286 0.278 rg 0.0438 Tc 1.024 0 Td (This )Tj 0.0342 Tc 2.376 0 Td (information )Tj 0.001 Tc 5.583 0 Td (was )Tj 0.0037 Tc 2.037 0 Td (used )Tj 0.0496 Tc 2.374 0 Td (to )Tj 0.0184 Tc 1.303 0 Td (guide )Tj 0.0457 Tc 2.77 0 Td (the )Tj 0.0201 Tc -21.632 -1.066 Td (children )Tj 0.361 0.361 0.357 rg 0.0496 Tc 4.178 0 Td (to )Tj 0.286 0.286 0.278 rg -0.0003 Tc 1.543 0 Td (cycle )Tj 0.05 Tc 10.5727 0 0 9.9 143.42 565.21 Tm (or )Tj 0.027 Tc 9.9 0 0 9.9 159.83 565.21 Tm (hyperventilate )Tj 0.05 Tc 10.1194 0 0 9.9 226.46 565.21 Tm (at )Tj 0.0258 Tc 9.9 0 0 9.9 241.91 565.21 Tm (rates )Tj 0.05 Tc 9.9231 0 0 9.9 269.26 565.21 Tm (that )Tj 0.22 0.22 0.212 rg -0.0006 Tc 9.9 0 0 9.9 59.51 554.17 Tm (resul)Tj 0.361 0.361 0.357 rg -0.0028 Tc 2.035 0 Td (ted )Tj 0.286 0.286 0.278 rg -0.0336 Tc 1.594 0 Td (in )Tj 0.0279 Tc 1.073 0 Td (minute )Tj 0.0244 Tc 3.2 0 Td (ventilation )Tj -0.007 Tc 4.842 0 Td (levels )Tj 0.0167 Tc 2.625 0 Td (needed )Tj 0.05 Tc 10.4772 0 0 9.9 243.33 554.17 Tm (to )Tj 0.0108 Tc 9.9 0 0 9.9 254.78 554.17 Tm (achieve )Tj 0.0215 Tc -19.725 -1.116 Td (the )Tj 0.0355 Tc 1.588 0 Td (same )Tj 0.0403 Tc 2.537 0 Td (pattern )Tj 0.05 Tc 10.5727 0 0 9.9 134.3 543.12 Tm (of )Tj 0.0387 Tc 9.9 0 0 9.9 146.41 543.12 Tm (breathing )Tj 0.05 Tc 10.0265 0 0 9.9 189.98 543.12 Tm (and )Tj 0.0457 Tc 9.9 0 0 9.9 209.74 543.12 Tm (the )Tj 0.0355 Tc 1.636 0 Td (same )Tj 0.157 0.157 0.153 rg 0 Tc 2.53 0 Td (R)Tj 0.286 0.286 0.278 rg 0.0473 Tc 0.729 0 Td (WL. )Tj 0.22 0.22 0.212 rg 0.0222 Tc -19.056 -1.114 Td (Both )Tj 0.286 0.286 0.278 rg 0.0053 Tc 2.572 0 Td (tests )Tj 0.0009 Tc 2.328 0 Td (were )Tj 0.0324 Tc 2.476 0 Td (performed )Tj 0.0167 Tc 4.991 0 Td (whilst )Tj 0.0326 Tc 3.105 0 Td (breathing )Tj 0.0313 Tc 4.498 0 Td (cold )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 9.8656 0 0 10.1 58.92 521.05 Tm (\(O\261O.SOC\), )Tj EMC ET BT /T1_0 1 Tf 0.041 Tc 9.9 0 0 9.9 113.19 521.05 Tm (dry )Tj 0.05 Tc 10.0881 0 0 9.9 134.3 521.05 Tm (air )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 9.8576 0 0 9.9 152.52 521.05 Tm (\(0 )Tj EMC ET BT /T1_0 1 Tf 0.0451 Tc 9.9 0 0 9.9 167.5 521.05 Tm (mgH)Tj 0 Tc 6.2 0 0 6.2 189.09 519.12 Tm (2)Tj 0.05 Tc 12.7164 0 0 10.1 192.83 521.05 Tm (0// )Tj 0.018 Tc 9.9 0 0 9.9 213.5 521.05 Tm (air\), )Tj 0.0088 Tc 2.482 0 Td (which )Tj 0.0252 Tc 3.2 0 Td (was )Tj 0.0186 Tc -21.298 -1.067 Td (supplied )Tj 0.0496 Tc 4.133 0 Td (to )Tj 0.0215 Tc 1.406 0 Td (the )Tj 0.0342 Tc 1.836 0 Td (inspiratory )Tj 0.0482 Tc 5.246 0 Td (port )Tj 0.05 Tc 11.1292 0 0 9.9 206.77 510.49 Tm (of )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0215 Tc 9.9 0 0 9.9 221.26 510.49 Tm (the )Tj EMC ET BT /T1_0 1 Tf 0.0278 Tc 9.9 0 0 9.9 239.5057 510.49 Tm (respiratory )Tj 0.0061 Tc -18.231 -1.116 Td (valve )Tj 0.0017 Tc 2.524 0 Td (box. )Tj /T1_1 1 Tf 0.05 Tc 12.2371 0 0 9.3 104.78 499.44 Tm (It )Tj /T1_0 1 Tf 0.001 Tc 9.9 0 0 9.9 115.19 499.44 Tm (was )Tj 0.0423 Tc 1.894 0 Td (prepared )Tj -0.0207 Tc 4.12 0 Td (by )Tj 0.019 Tc 1.359 0 Td (passing )Tj 0.0276 Tc 3.382 0 Td (compressed )Tj 0.05 Tc 10.0881 0 0 9.9 273.98 499.44 Tm (air )Tj 0.0396 Tc 9.9 0 0 9.9 59.02 488.41 Tm (through )Tj 0.0181 Tc 3.871 0 Td (calcium )Tj 0.034 Tc 3.733 0 Td (chloride )Tj 0.05 Tc 10.3398 0 0 9.9 173.65 488.41 Tm (and )Tj 0 Tc 9.9 0 0 9.9 194.3 488.41 Tm (a )Tj 0.042 Tc 0.97 0 Td (copper )Tj 0.0167 Tc 3.394 0 Td (coil, )Tj 0.0088 Tc 2.336 0 Td (which )Tj 0.0252 Tc -20.412 -1.068 Td (was )Tj 0.0145 Tc 1.835 0 Td (immersed )Tj -0.0336 Tc 4.364 0 Td (in )Tj 0.05 Tc 10.2654 0 0 9.9 129.98 477.84 Tm (an )Tj 0.0005 Tc 9.9 0 0 9.9 142.96 477.84 Tm (iced )Tj 0.0406 Tc 1.946 0 Td (water )Tj 0.0432 Tc 2.62 0 Td (bath, )Tj 0.05 Tc 10.0265 0 0 9.9 212.06 477.84 Tm (and )Tj 0.0416 Tc 9.9 0 0 9.9 230.38 477.84 Tm (then )Tj 0.0477 Tc 2.133 0 Td (through )Tj 0 Tc -19.499 -1.114 Td (a )Tj 0.0252 Tc 0.82 0 Td (simple )Tj 0.0244 Tc 3.165 0 Td (refrigeration )Tj 0.0115 Tc 5.664 0 Td (circuit. )Tj 0.22 0.22 0.212 rg 0.05 Tc 9.9723 0 0 9.9 186.63 466.81 Tm (The )Tj 0.286 0.286 0.278 rg 0.023 Tc 9.9 0 0 9.9 207.34 466.81 Tm (tubing )Tj 0.0125 Tc 3.042 0 Td (system )Tj 0.22 0.22 0.212 rg 0.0031 Tc 3.262 0 Td (wa)Tj 0.361 0.361 0.357 rg 0 Tc 1.199 0 Td (s )Tj -22.485 -1.116 Td (t)Tj 0.22 0.22 0.212 rg 0.0198 Tc 0.292 0 Td (hermally )Tj 0.286 0.286 0.278 rg 0.024 Tc 4.502 0 Td (insulated )Tj 0 Tc 4.653 0 Td (a)Tj 0.157 0.157 0.153 rg 0.542 0 Td (n)Tj 0.286 0.286 0.278 rg 0.477 0 Td (d )Tj 0.0215 Tc 1.365 0 Td (the )Tj 0.0421 Tc 2.085 0 Td (temperature )Tj 0.05 Tc 11.1292 0 0 9.9 255.73 455.76 Tm (of )Tj 0.361 0.361 0.357 rg 0.0457 Tc 9.9 0 0 9.9 272.62 455.76 Tm (the )Tj 0.286 0.286 0.278 rg 0.0204 Tc -21.63 -1.115 Td (inspired )Tj 0.0201 Tc 3.733 0 Td (gas )Tj 0.001 Tc 1.704 0 Td (was )Tj 0.0287 Tc 1.89 0 Td (measured )Tj 0 Tc 4.477 0 Td (1 )Tj 0.05 Tc 9.9821 0 0 9.9 182.29 444.72 Tm (em )Tj 0.0247 Tc 9.9 0 0 9.9 198.61 444.72 Tm (from )Tj 0.361 0.361 0.357 rg 0.0215 Tc 2.433 0 Td (the )Tj 0.286 0.286 0.278 rg 0.039 Tc 1.594 0 Td (inspiratory )Tj 0.05 Tc 10.1428 0 0 9.9 58.58 434.16 Tm (port )Tj 10.7518 0 0 9.9 82.45 434.16 Tm (at )Tj 0.0215 Tc 9.9 0 0 9.9 97.42 434.16 Tm (the )Tj 0.0061 Tc 1.939 0 Td (valve )Tj 0.0063 Tc 2.864 0 Td (box )Tj 0.0236 Tc 2.228 0 Td (with )Tj 0.05 Tc 10.2654 0 0 9.9 191.42 434.16 Tm (an )Tj 0.0391 Tc 9.9 0 0 9.9 208.22 434.16 Tm (accurate )Tj 0.0196 Tc 4.275 0 Td (mercury )Tj 0.0293 Tc -19.394 -1.115 Td (thermometer. )Tj 0.05 Tc 9.9723 0 0 9.9 117.99 423.12 Tm (The )Tj 0.0373 Tc 9.9 0 0 9.9 137.74 423.12 Tm (temperature )Tj 0.05 Tc 11.1292 0 0 9.9 191.41 423.12 Tm (of )Tj 0.0215 Tc 9.9 0 0 9.9 203.5 423.12 Tm (the )Tj 0.361 0.361 0.357 rg 0.0187 Tc 1.542 0 Td (expire)Tj 0.22 0.22 0.212 rg 0 Tc 2.62 0 Td (d )Tj 0.286 0.286 0.278 rg 0.0201 Tc 0.825 0 Td (gas )Tj 0.001 Tc 1.656 0 Td (was )Tj 0.157 0.157 0.153 rg 0 Tc -21.333 -1.114 Td (r)Tj 0.286 0.286 0.278 rg 0.0258 Tc 0.378 0 Td (ecorded )Tj 0.05 Tc 10.1124 0 0 9.9 99.74 412.09 Tm (dur)Tj 0.157 0.157 0.153 rg -0.0336 Tc 9.9 0 0 9.9 114.64 412.09 Tm (in)Tj 0.286 0.286 0.278 rg 0 Tc 0.776 0 Td (g )Tj 0.0065 Tc 0.918 0 Td (exercise )Tj 0.0075 Tc 3.792 0 Td (with )Tj 0 Tc 2.27 0 Td (a )Tj 0.22 0.22 0.212 rg 0.0069 Tc 0.979 0 Td (high )Tj 0.02 Tc 2.327 0 Td (response )Tj 0.286 0.286 0.278 rg 0.0139 Tc 4.169 0 Td (ther\255)Tj 0.043 Tc -20.945 -1.115 Td (mistor )Tj 0.0263 Tc 3.19 0 Td (\(Model )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0063 Tc 9.9 0 0 9.9 124.6687 401.0515 Tm (530, )Tj EMC ET BT 0.22 0.22 0.212 rg /T1_0 1 Tf 0.0145 Tc 9.9 0 0 9.9 145.9042 401.0515 Tm (Yellow )Tj ET BT /Suspect <>BDC 0.286 0.286 0.278 rg /T1_0 1 Tf 0.0299 Tc 9.9 0 0 9.9 179.8216 401.0515 Tm (Springs )Tj EMC ET BT 0.22 0.22 0.212 rg /T1_0 1 Tf 0.0486 Tc 9.9 0 0 9.9 215.9269 401.0515 Tm (Instrument )Tj 0.286 0.286 0.278 rg 0.0337 Tc 5.185 0 Td (Co., )Tj ET BT /Suspect <>BDC 0.22 0.22 0.212 rg /T1_0 1 Tf 0.05 Tc 9.9307 0 0 9.9 57.98 390 Tm (Ohio)Tj 0.478 0.478 0.471 rg 0 Tc 9.9 0 0 9.9 79.53 390 Tm (, )Tj EMC /Suspect <>BDC 0.286 0.286 0.278 rg 0.0222 Tc 0.547 0 Td (USA\). )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 9.9723 0 0 9.9 114.63 390 Tm (The )Tj 0.0343 Tc 9.9 0 0 9.9 134.38 390 Tm (thermistor )Tj 0.0317 Tc 4.752 0 Td (tip )Tj 0.001 Tc 1.456 0 Td (was )Tj 0.0281 Tc 1.829 0 Td (suspended )Tj 0.05 Tc 10.1194 0 0 9.9 261.02 390 Tm (at )Tj 0.0215 Tc 9.9 0 0 9.9 272.14 390 Tm (the )Tj 0.0461 Tc -21.682 -1.114 Td (entrance )Tj 0.0011 Tc 4.082 0 Td (to )Tj 0.0215 Tc 1.212 0 Td (the )Tj 0.0407 Tc 1.649 0 Td (rubber )Tj 0.0414 Tc 3.199 0 Td (mouth )Tj -0.003 Tc 3.156 0 Td (piece )Tj 0.0149 Tc 2.463 0 Td (in )Tj 0.0281 Tc 1.109 0 Td (such )Tj 0 Tc 2.331 0 Td (a )Tj 0.0182 Tc 0.833 0 Td (way )Tj 0.0033 Tc 2.076 0 Td (as )Tj 0.0496 Tc -22.053 -1.115 Td (to )Tj -0.0122 Tc 1.264 0 Td (be )Tj 0.0081 Tc 1.307 0 Td (wholly )Tj 0.0139 Tc 3.2 0 Td (within )Tj 0.361 0.361 0.357 rg 0.0215 Tc 3.054 0 Td (the )Tj 0.286 0.286 0.278 rg 0.05 Tc 9.9163 0 0 9.9 161.74 367.93 Tm (mouth, )Tj 10.18 0 0 9.9 195.85 367.93 Tm (but )Tj 10.4827 0 0 9.9 213.59 367.93 Tm (not )Tj 0.0341 Tc 9.9 0 0 9.9 231.34 367.93 Tm (touching )Tj 0.0215 Tc 4.121 0 Td (the )Tj 0.0159 Tc -21.685 -1.067 Td (sides )Tj 0.05 Tc 10.5727 0 0 9.9 81.98 357.37 Tm (of )Tj 0.0215 Tc 9.9 0 0 9.9 95.02 357.37 Tm (the )Tj 0.0424 Tc 1.697 0 Td (tubing )Tj 0.05 Tc 10.5727 0 0 9.9 142.94 357.37 Tm (or )Tj 0.0457 Tc 9.9 0 0 9.9 156.46 357.37 Tm (the )Tj 0.0226 Tc 1.745 0 Td (tongue. )Tj 0.0169 Tc 3.631 0 Td (Its )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 10.0624 0 0 9.9 224.05 357.37 Tm (90% )Tj EMC ET BT /T1_0 1 Tf 0.0269 Tc 9.9 0 0 9.9 248.15 357.37 Tm (response )Tj 0.22 0.22 0.212 rg 0.0074 Tc -19.201 -1.115 Td (time )Tj 0.286 0.286 0.278 rg 0.0496 Tc 2.133 0 Td (to )Tj 0 Tc 1.107 0 Td (a )Tj 0.0302 Tc 0.772 0 Td (sudden )Tj 0.0421 Tc 3.309 0 Td (temperature )Tj 0.0394 Tc 5.422 0 Td (change )Tj 0.0252 Tc 3.306 0 Td (was )Tj 0.0423 Tc 1.881 0 Td (found )Tj 0.0496 Tc 2.87 0 Td (to )Tj -0.0122 Tc 1.167 0 Td (be )Tj ET BT /Suspect <>BDC 0.22 0.22 0.212 rg /T1_0 1 Tf 0 Tc 9.9 0 0 9.9 57.5057 335.2831 Tm (0)Tj 0.361 0.361 0.357 rg -0.035 Tc 9.2844 0 0 9.9 62.69 335.28 Tm (.51 )Tj EMC ET BT /T1_0 1 Tf -0.0319 Tc 9.9 0 0 9.9 78.1 335.28 Tm (s. )Tj 0.22 0.22 0.212 rg 0.05 Tc 9.9723 0 0 9.9 87.75 335.28 Tm (The )Tj 0.286 0.286 0.278 rg 0.0254 Tc 9.9 0 0 9.9 107.99 335.28 Tm (humidity )Tj 0.05 Tc 11.1292 0 0 9.9 149.17 335.28 Tm (of )Tj 0.0457 Tc 9.9 0 0 9.9 161.26 335.28 Tm (the )Tj 0.0204 Tc 1.642 0 Td (inspired )Tj 0.0201 Tc 3.733 0 Td (gas )Tj 0.22 0.22 0.212 rg 0.0252 Tc 1.704 0 Td (was )Tj 0.286 0.286 0.278 rg 0.0237 Tc 1.93 0 Td (checked )Tj -0.0207 Tc -19.431 -1.114 Td (by )Tj 0.0096 Tc 1.695 0 Td (weighing )Tj 0 Tc 4.5 0 Td (a )Tj 0.0231 Tc 1.16 0 Td (small )Tj 0.0303 Tc 2.962 0 Td (canister )Tj 0.0347 Tc 4.024 0 Td (containing )Tj 0.0181 Tc 5.236 0 Td (calcium )Tj 0.0271 Tc -19.636 -1.115 Td (chloride )Tj 0.0249 Tc 3.89 0 Td (before )Tj 0.05 Tc 10.3398 0 0 9.9 126.13 313.21 Tm (and )Tj 0.0425 Tc 9.9 0 0 9.9 145.82 313.21 Tm (after )Tj 0.0457 Tc 2.432 0 Td (the )Tj 0.0251 Tc 1.75 0 Td (passage )Tj 0.05 Tc 11.1292 0 0 9.9 223.09 313.21 Tm (of )Tj 0.0402 Tc 9.9 0 0 9.9 236.06 313.21 Tm (one )Tj 0.0142 Tc 1.941 0 Td (litre )Tj 0.05 Tc 11.1292 0 0 9.9 275.89 313.21 Tm (of )Tj 0.0457 Tc 9.9 0 0 9.9 57.58 302.16 Tm (the )Tj 0.0134 Tc 1.642 0 Td (inspired )Tj 0.0201 Tc 3.685 0 Td (gas)Tj 0.063 0.067 0.055 rg 0 Tc 1.441 0 Td (. )Tj 0.22 0.22 0.212 rg 0.05 Tc 9.9723 0 0 9.9 129.51 302.16 Tm (The )Tj 0.286 0.286 0.278 rg 0.0406 Tc 9.9 0 0 9.9 149.27 302.16 Tm (water )Tj 0.0467 Tc 2.658 0 Td (content )Tj 0.05 Tc 11.6856 0 0 9.9 210.61 302.16 Tm (of )Tj 0.0457 Tc 9.9 0 0 9.9 222.7 302.16 Tm (the )Tj 0.0211 Tc 1.591 0 Td (expired )Tj 0.0366 Tc 3.492 0 Td (air )Tj 0.001 Tc -21.761 -1.115 Td (was )Tj 0.0267 Tc 1.882 0 Td (calculated )Tj 0.0372 Tc 4.655 0 Td (assuming )Tj -0.0162 Tc (full )Tj 0.0442 Tc 6.105 0 Td (saturation. )Tj 0.22 0.22 0.212 rg 0.05 Tc 9.9723 0 0 9.9 67.11 280.56 Tm (The )Tj 10.1524 0 0 9.9 87.79 280.56 Tm (RWL )Tj 0.286 0.286 0.278 rg -0.0336 Tc 9.9 0 0 9.9 115.12 280.56 Tm (in )Tj 0.027 Tc 1.212 0 Td (g/min )Tj 0.001 Tc 2.868 0 Td (was )Tj 0.0321 Tc 1.93 0 Td (calculated )Tj 0.22 0.22 0.212 rg -0.0207 Tc 4.763 0 Td (by )Tj 0.286 0.286 0.278 rg 0.0239 Tc 1.403 0 Td (multiplying )Tj 0.0215 Tc -17.988 -1.114 Td (the )Tj 0.0279 Tc 1.939 0 Td (minute )Tj 0.0244 Tc 3.588 0 Td (ventilation )Tj -0.0207 Tc 5.239 0 Td (by )Tj 0.0215 Tc 1.645 0 Td (the )Tj 0.0145 Tc 1.884 0 Td (difference )Tj 0.0149 Tc 4.801 0 Td (in )Tj 0.0284 Tc 1.462 0 Td (water )Tj 0.0468 Tc -20.664 -1.115 Td (contents )Tj 0.0207 Tc 3.987 0 Td (between )Tj 0.0204 Tc 3.821 0 Td (inspired )Tj 0.05 Tc 10.0265 0 0 9.9 170.78 258.49 Tm (and )Tj 0.0211 Tc 9.9 0 0 9.9 189.97 258.49 Tm (expired )Tj 0.0219 Tc 3.492 0 Td (air. )Tj 0.05 Tc 10.2656 0 0 9.9 241.83 258.49 Tm (The )Tj 0.22 0.22 0.212 rg 10.3069 0 0 9.9 262.51 258.49 Tm (RHL )Tj 0.286 0.286 0.278 rg 0.0252 Tc 9.9 0 0 9.9 57.11 247.44 Tm (was )Tj 0.0321 Tc 1.93 0 Td (calculated )Tj 0.0041 Tc 4.762 0 Td (using )Tj 0.0215 Tc 2.616 0 Td (the )Tj 0.05 Tc 9.9304 0 0 9.9 165.49 247.44 Tm (equation )Tj 11.1292 0 0 9.9 206.77 247.44 Tm (of )Tj 8.0645 0 0 7.9001 219.8 247.44 Tm (DEAL )Tj /T1_2 1 Tf 10.1514 0 0 9.5 245.67 247.44 Tm (et )Tj -0.0038 Tc 9.5 0 0 9.5 257.22 247.44 Tm (a/. )Tj /T1_0 1 Tf -0.035 Tc 9.4074 0 0 9.9 271.45 247.44 Tm ([7]. )Tj 0.157 0.157 0.153 rg 0 Tc 9.9 0 0 9.9 57.04 236.89 Tm (T)Tj 0.286 0.286 0.278 rg 0.0306 Tc 0.686 0 Td (he )Tj 0.009 Tc 1.441 0 Td (severity )Tj 0.05 Tc 11.1292 0 0 9.9 114.61 236.89 Tm (of )Tj 0.0215 Tc 9.9 0 0 9.9 128.62 236.89 Tm (the )Tj 0.025 Tc 1.739 0 Td (induced )Tj 0.05 Tc 10.0133 0 0 9.9 183.74 236.89 Tm (asthma )Tj -0.0195 Tc 9.9 0 0 9.9 219.28 236.89 Tm (is )Tj 0.0191 Tc 1.064 0 Td (expressed )Tj 0.05 Tc 9.9203 0 0 9.9 275.42 236.89 Tm (as )Tj 0.0363 Tc 9.9 0 0 9.9 57.1 225.85 Tm (maxima)Tj 0.157 0.157 0.153 rg 0 Tc 3.436 0 Td (l )Tj 0.286 0.286 0.278 rg 0.05 Tc 10.0942 0 0 9.9 96.98 225.85 Tm (post )Tj 0.0152 Tc 9.9 0 0 9.9 118.46 225.85 Tm (challenge )Tj -0.0134 Tc 4.363 0 Td (fall )Tj 0.0149 Tc 1.7 0 Td (in )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 10.2291 0 0 9.9 190.04 225.85 Tm (FEV )Tj EMC ET BT /T1_0 1 Tf 0 Tc 6.2 0 0 6.2 211.47 223.44 Tm (1 )Tj 0.05 Tc 9.9203 0 0 9.9 217.82 225.85 Tm (as )Tj 0 Tc 9.9 0 0 9.9 230.3 225.85 Tm (a )Tj 0.0322 Tc 0.836 0 Td (percentage )Tj 0.05 Tc 11.1292 0 0 9.9 57.01 214.8 Tm (of )Tj 0.0457 Tc 9.9 0 0 9.9 69.1 214.8 Tm (the )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0119 Tc 9.9 0 0 9.9 85.93 214.8 Tm (baseline )Tj EMC ET BT /T1_0 1 Tf 0.0182 Tc 9.9 0 0 9.9 122.857 214.8 Tm (value )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0205 Tc 9.9 0 0 9.9 148.6762 214.8 Tm (\(.1FEY )Tj EMC ET BT 0.22 0.22 0.212 rg /T1_0 1 Tf 0 Tc 6.2 0 0 6.2 179.79 212.41 Tm (1 )Tj 0.286 0.286 0.278 rg 0.05 Tc 10.4409 0 0 9.9 183.73 214.8 Tm (%\) )Tj 0.0032 Tc 9.9 0 0 9.9 200.07 214.8 Tm (defined )Tj -0.0156 Tc 3.441 0 Td (as: )Tj 0.157 0.157 0.153 rg 0 Tc -9.691 -1.89 Td (B)Tj 0.286 0.286 0.278 rg 0.0166 Tc 0.624 0 Td (aseline )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 10.0617 0 0 9.5 176.4 196.09 Tm (FEV )Tj EMC ET BT /T1_1 1 Tf 0 Tc 5.5001 0 0 5.5001 197.59 193.69 Tm (1 )Tj 0.549 g 1.331 0.436 Td (-)Tj ET BT /Suspect <>BDC 0.286 0.286 0.278 rg /T1_0 1 Tf 0.0299 Tc 9.9 0 0 9.9 56.43 183.61 Tm (.1FEY )Tj EMC ET BT 0.361 0.361 0.357 rg /T1_0 1 Tf 0.05 Tc 12.2567 0 0 9.9 88.17 183.61 Tm (\(%\)=)Tj 0.22 0.22 0.212 rg 0 Tc 9.9 0 0 9.9 118.03 183.61 Tm (L)Tj 0.361 0.361 0.357 rg 0.0163 Tc 0.625 0 Td (owest )Tj 0.286 0.286 0.278 rg 0.0456 Tc 2.824 0 Td (post )Tj 0.0135 Tc 2.072 0 Td (exercise )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 10.2291 0 0 9.9 209.72 183.61 Tm (FEY)Tj 0 Tc 6.2 0 0 6.2 230.67 182.65 Tm (1 )Tj EMC ET BT /T1_0 1 Tf 9.9 0 0 9.9 239.01 183.61 Tm (x )Tj ET BT /Suspect <>BDC 0.22 0.22 0.212 rg /T1_0 1 Tf -0.0113 Tc 9.9 0 0 9.9 247.3359 179.7589 Tm (100 )Tj EMC ET BT 0.361 0.361 0.357 rg /T1_0 1 Tf 0 Tc 6.4001 0 0 6.4001 84.26 177.37 Tm (1 )Tj 0.286 0.286 0.278 rg 0.0037 Tc 9.9 0 0 9.9 144.92 173.05 Tm (Baseline )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 9.8221 0 0 9.5 182.64 173.05 Tm (FEY )Tj EMC ET BT /T1_0 1 Tf 0 Tc 6.4001 0 0 6.4001 203.78 170.65 Tm (1 )Tj 0.22 0.22 0.212 rg 0.0213 Tc 9.9 0 0 9.9 56.6 154.33 Tm (Predicted )Tj 0.286 0.286 0.278 rg 0.0143 Tc 4.608 0 Td (values )Tj 0.0377 Tc 3.239 0 Td (for )Tj ET BT /Suspect <>BDC 0.22 0.22 0.212 rg /T1_1 1 Tf 0.05 Tc 9.8221 0 0 9.5 152.88 154.33 Tm (FEV )Tj EMC ET BT 0.286 0.286 0.278 rg /T1_1 1 Tf 0 Tc 5.5001 0 0 5.5001 174.07 151.93 Tm (1 )Tj /T1_0 1 Tf 0.05 Tc 10.0265 0 0 9.9 183.26 154.33 Tm (and )Tj 0.0448 Tc 9.9 0 0 9.9 204.94 154.33 Tm (maximum )Tj 0.0167 Tc 4.889 0 Td (oxygen )Tj 0.0433 Tc -19.927 -1.115 Td (consumption )Tj 0.0171 Tc 6.409 0 Td (were )Tj 0.0267 Tc 2.803 0 Td (calculated )Tj 0.0086 Tc 5.187 0 Td (from )Tj 0.0215 Tc 2.918 0 Td (the )Tj 0.05 Tc 10.377 0 0 9.9 248.06 143.29 Tm (data )Tj 11.1292 0 0 9.9 274.93 143.29 Tm (of )Tj ET BT /Suspect <>BDC 0.22 0.22 0.212 rg /T1_0 1 Tf 8.5298 0 0 7.9001 56.56 132.25 Tm (GOD)Tj 0.361 0.361 0.357 rg -0.035 Tc 7.8953 0 0 7.9001 75.81 132.25 Tm (FREY )Tj EMC /Suspect <>BDC 0.286 0.286 0.278 rg 9.671 0 0 10.1 99.13 132.25 Tm ([I )Tj EMC /Suspect <>BDC 9.6833 0 0 10.1 106.46 132.25 Tm (0]. )Tj EMC ET BT /T1_0 1 Tf 0.022 Tc 9.9 0 0 9.9 66.06 121.2 Tm (Statistical )Tj 0.0351 Tc 4.469 0 Td (comparisons )Tj 0.0171 Tc 5.682 0 Td (were )Tj 0.0401 Tc 2.278 0 Td (made )Tj -0.0207 Tc 2.621 0 Td (by )Tj 0.0298 Tc 1.258 0 Td (means )Tj 0.05 Tc 11.1292 0 0 9.9 257.17 121.2 Tm (of )Tj 10.088 0 0 9.9 268.22 121.2 Tm (one )Tj 0.0182 Tc 9.9 0 0 9.9 56.15 110.64 Tm (way )Tj 0.0198 Tc 1.979 0 Td (analysis )Tj 0.05 Tc 11.1292 0 0 9.9 111.73 110.64 Tm (of )Tj 0.0302 Tc 9.9 0 0 9.9 123.34 110.64 Tm (variance )Tj 0.0355 Tc 3.871 0 Td (and )Tj 0.0278 Tc 1.902 0 Td (by )Tj 0.0359 Tc 1.262 0 Td (paired )Tj 0.022 Tc 3.002 0 Td (t-test, )Tj 0.0075 Tc 2.716 0 Td (with )Tj 0.0457 Tc 2.132 0 Td (the )Tj -0.0327 Tc -21.63 -1.115 Td (level )Tj 0.05 Tc 10.5727 0 0 9.9 78.62 99.6 Tm (of )Tj 0.0088 Tc 9.9 0 0 9.9 90.58 99.6 Tm (significance )Tj 0.0171 Tc 5.3 0 Td (being )Tj 0.0417 Tc 2.664 0 Td (taken )Tj 0.05 Tc 9.9203 0 0 9.9 196.22 99.6 Tm (as )Tj 0 Tc 9.9 0 0 9.9 208.82 99.6 Tm (p )Tj 0.361 0.361 0.357 rg /T1_1 1 Tf 10.5 0 0 10.5 215.35 99.6 Tm (< )Tj ET BT /Suspect <>BDC 0.286 0.286 0.278 rg /T1_0 1 Tf 0.0024 Tc 9.9 0 0 9.9 223.58 99.6 Tm (0.05. )Tj EMC /Suspect <>BDC 0.157 0.157 0.153 rg /T1_1 1 Tf -0.035 Tc 4.7371 0 0 6 313.85 488.41 Tm (C\273 )Tj EMC ET BT /T1_0 1 Tf 0 Tc 9.8 0 0 9.8 313.82 482.65 Tm (c )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 16.5624 0 0 10.4 312.27 471.12 Tm ('i )Tj EMC /Suspect <>BDC 0.22 0.22 0.212 rg 7.0236 0 0 6.3001 313.9 465.37 Tm (vt )Tj EMC /Suspect <>BDC 0.157 0.157 0.153 rg /T1_0 1 Tf 0 Tc 17.9 0 0 17.9 314.06 451.93 Tm (" )Tj EMC /Suspect <>BDC 0.0303 Tc 5.8001 0 0 5.8001 312.36 453.84 Tm (.J:l )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 7.2 0 0 7.2 312 442.81 Tm <007E0020>Tj EMC /Suspect <>BDC 0.22 0.22 0.212 rg /T1_0 1 Tf 12.3 0 0 12.3 312.28 438.97 Tm (\225 )Tj EMC ET BT /T1_1 1 Tf 10.5 0 0 10.5 312.31 420.72 Tm (> )Tj 0.157 0.157 0.153 rg 0.0076 Tc 6.5001 0 0 6.5001 312.33 414.97 Tm (UJ )Tj /T1_0 1 Tf 0.0277 Tc 10.5 0 0 10.5 312 408.25 Tm (u. )Tj ET BT /Suspect <>BDC 0.286 0.286 0.278 rg /T1_0 1 Tf 0 Tc 15.2 0 0 15.2 312.16 392.89 Tm (.)Tj 0.157 0.157 0.153 rg 0.133 0 Td (s )Tj EMC /Suspect <>BDC /T1_3 1 Tf 17.2001 0 0 17.2001 312.08 370.33 Tm (& )Tj EMC /Suspect <>BDC 0.22 0.22 0.212 rg /T1_0 1 Tf 0.05 Tc 10.4235 0 0 9.8 327.24 548.41 Tm (30 )Tj EMC ET BT /T1_1 1 Tf -0.0314 Tc 10 0 0 10 327.76 513.36 Tm (25 )Tj ET BT /Suspect <>BDC 0.157 0.157 0.153 rg /T1_0 1 Tf -0.035 Tc 10.6543 0 0 11 327.78 475.93 Tm (20 )Tj EMC ET BT /T1_1 1 Tf 8.733 0 0 10 329.48 439.93 Tm (15 )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 9.2182 0 0 10.6 328.98 402.97 Tm (10 )Tj EMC ET BT /T1_0 1 Tf 0 Tc 11 0 0 11 333.45 366.97 Tm (5 )Tj ET BT /Suspect <>BDC 0.22 0.22 0.212 rg /T1_0 1 Tf 9.7 0 0 9.7 333.98 331.44 Tm (0 )Tj EMC ET BT 0.157 0.157 0.153 rg /T1_0 1 Tf 0.0475 Tc 10.5 0 0 10.5 473.69 322.81 Tm (Isocapni)Tj 0.286 0.286 0.278 rg 0 Tc 3.746 0 Td (c )Tj ET BT /Suspect <>BDC 0.157 0.157 0.153 rg /C0_0 1 Tf 4.9601 0 0 7.68 463.68 310.81 Tm <004800790070007E007200760065006E0074>Tj 0.063 0.067 0.055 rg 1.92 0 0 7.68 508.8 310.81 Tm <0069>Tj 0.157 0.157 0.153 rg 3.92 0 0 7.68 511.68 310.81 Tm <006C006100740069006F006E0020>Tj EMC ET BT 0.286 0.286 0.278 rg /T1_0 1 Tf 0.05 Tc 8.591 0 0 8.1 309.03 295.44 Tm (fig)Tj 0.478 0.478 0.471 rg 0 Tc 8.1 0 0 8.1 320.47 295.44 Tm (. )Tj ET BT /Suspect <>BDC 0.286 0.286 0.278 rg /T1_1 1 Tf 0.05 Tc 7.8667 0 0 7.8001 325.22 295.44 Tm (I. )Tj EMC ET BT /T1_0 1 Tf 8.2125 0 0 8.1 338.33 295.44 Tm (The )Tj 0.009 Tc 8.1 0 0 8.1 356.53 295.44 Tm (severity )Tj 0.05 Tc 8.9033 0 0 8.1 387.27 295.44 Tm (of )Tj 0.0011 Tc 8.1 0 0 8.1 399.27 295.44 Tm (exercise )Tj 0.05 Tc 8.1466 0 0 8.1 430.48 295.44 Tm (and )Tj 0.0221 Tc 8.1 0 0 8.1 448.31 295.44 Tm (hyperventilation )Tj 0.0187 Tc 7.519 0 Td (induced )Tj 0.0409 Tc -24.772 -1.065 Td (asthma)Tj 0.157 0.157 0.153 rg 0 Tc 3.07 0 Td (. )Tj 0.286 0.286 0.278 rg 0.0311 Tc 0.609 0 Td (Both )Tj 0.0013 Tc 2.491 0 Td (tests )Tj 0.22 0.22 0.212 rg -0.0134 Tc 2.194 0 Td (were )Tj 0.286 0.286 0.278 rg 0.0216 Tc 2.314 0 Td (performed )Tj 0.0386 Tc 4.799 0 Td (under )Tj 0.043 Tc 2.783 0 Td (the )Tj 0.0158 Tc 1.707 0 Td (same )Tj 0.0269 Tc 2.433 0 Td (conditions )Tj 0.05 Tc 8.9033 0 0 8.1 528.88 286.81 Tm (of )Tj 0.0235 Tc 8.1 0 0 8.1 308.63 277.69 Tm (respiratory )Tj 0.0415 Tc 4.921 0 Td (beat )Tj 0.22 0.22 0.212 rg -0.0124 Tc (los)Tj 0.361 0.361 0.357 rg 0 Tc 3.244 0 Td (s )Tj 0.286 0.286 0.278 rg 0.05 Tc 8.1466 0 0 8.1 380.08 277.69 Tm (and )Tj 0.0235 Tc 8.1 0 0 8.1 395.99 277.69 Tm (respiratory )Tj 0.0244 Tc 4.919 0 Td (water )Tj 0.22 0.22 0.212 rg 0.0003 Tc 2.659 0 Td (loss)Tj 0.361 0.361 0.357 rg 0 Tc 1.528 0 Td (. )Tj 0.286 0.286 0.278 rg 0.05 Tc 8.2125 0 0 8.1 474.17 277.69 Tm (The )Tj 0.0311 Tc 8.1 0 0 8.1 490.06 277.69 Tm (mean )Tj ET BT /Suspect <>BDC 0.478 0.478 0.471 rg /T1_1 1 Tf 0 Tc 8.5 0 0 8.5 509.67 277.69 Tm (\261)Tj 0.286 0.286 0.278 rg -0.035 Tc 5.5807 0 0 8.5 515.95 277.69 Tm (sE.M )Tj EMC ET BT 0.22 0.22 0.212 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 530.81 277.69 Tm (i)Tj 0.361 0.361 0.357 rg 0.232 0 Td (s )Tj 0.286 0.286 0.278 rg -0.018 Tc -27.669 -1.127 Td (given )Tj 0.0296 Tc 2.546 0 Td (for )Tj 0.361 0.361 0.357 rg 0.0093 Tc 1.541 0 Td (each )Tj 0.286 0.286 0.278 rg -0.0084 Tc 2.32 0 Td (test. )Tj 0.157 0.157 0.153 rg 0.0084 Tc 9.9 0 0 9.9 406.99 236.41 Tm (Re)Tj 0.286 0.286 0.278 rg 0 Tc 1.106 0 Td (s)Tj 0.157 0.157 0.153 rg 0.0202 Tc 0.451 0 Td (ults )Tj 0.22 0.22 0.212 rg 0.0371 Tc -10.477 -1.648 Td (Mean )Tj ET BT /Suspect <>BDC 0.286 0.286 0.278 rg /T1_0 1 Tf 0.05 Tc 8.9141 0 0 7.9001 346.94 220.09 Tm (\(\261SEM\) )Tj EMC ET BT /T1_0 1 Tf 0.0143 Tc 9.9 0 0 9.9 382.54 220.09 Tm (values )Tj 0.05 Tc 11.1292 0 0 9.9 413.17 220.09 Tm (of )Tj 0.22 0.22 0.212 rg 0.0188 Tc 9.9 0 0 9.9 426.25 220.09 Tm (baseline )Tj ET BT /Suspect <>BDC 0.286 0.286 0.278 rg /T1_0 1 Tf 0.05 Tc 9.9856 0 0 9.9 464.6 220.09 Tm (FEY)Tj 0 Tc 6.2 0 0 6.2 485.07 217.69 Tm (1 )Tj EMC ET BT /T1_0 1 Tf 0.0033 Tc 9.9 0 0 9.9 493.34 220.09 Tm (as )Tj -0.022 Tc 1.27 0 Td (well )Tj 0.0033 Tc 2.124 0 Td (as )Tj 0.0435 Tc -22.053 -1.115 Td (var)Tj 0.157 0.157 0.153 rg 0 Tc 1.352 0 Td (i)Tj 0.286 0.286 0.278 rg 0.043 Tc 0.289 0 Td (ous )Tj 0.0422 Tc 2.145 0 Td (parameters )Tj 0.0379 Tc 5.467 0 Td (obtained )Tj 0.22 0.22 0.212 rg 0.05 Tc 9.9334 0 0 9.9 443.91 209.05 Tm (during )Tj 0.286 0.286 0.278 rg 0.0215 Tc 9.9 0 0 9.9 479.02 209.05 Tm (the )Tj 0.0279 Tc 1.982 0 Td (last )Tj 0.0032 Tc 2.188 0 Td (two )Tj 0.0231 Tc -21.382 -1.115 Td (minutes )Tj 0.05 Tc 10.5727 0 0 9.9 345.5 198.01 Tm (of )Tj 0.0215 Tc 9.9 0 0 9.9 358.06 198.01 Tm (the )Tj 0.22 0.22 0.212 rg -0.035 Tc 9.844 0 0 9.9 374.86 198.01 Tm (te)Tj 0.361 0.361 0.357 rg 0.0427 Tc 9.9 0 0 9.9 381.94 198.01 Tm (sts )Tj 0.286 0.286 0.278 rg 0 Tc 1.507 0 Td (a)Tj 0.157 0.157 0.153 rg 0.542 0 Td (r)Tj 0.286 0.286 0.278 rg 0.329 0 Td (e )Tj 0.0324 Tc 0.821 0 Td (shown )Tj 0.0149 Tc 3.158 0 Td (in )Tj 0.0368 Tc 1.218 0 Td (table )Tj -0.035 Tc 9.6538 0 0 9.9 481.38 198.01 Tm (2. )Tj 0.22 0.22 0.212 rg 0.05 Tc 9.9723 0 0 9.9 492.39 198.01 Tm (The )Tj 0.286 0.286 0.278 rg 0.0239 Tc 9.9 0 0 9.9 513.1 198.01 Tm (mean )Tj 0.0167 Tc -20.711 -1.115 Td (oxygen )Tj 0.361 0.361 0.357 rg 0.0433 Tc 3.442 0 Td (consumption )Tj 0.286 0.286 0.278 rg 0.0377 Tc 6.011 0 Td (for )Tj 0.0457 Tc 1.706 0 Td (the )Tj 0.0065 Tc 1.688 0 Td (exercise )Tj 0.0398 Tc 3.742 0 Td (test )Tj 0.0495 Tc 1.843 0 Td (was )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 10.9018 0 0 9.9 511.13 186.97 Tm (20\261 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0 Tc 9.4 0 0 9.4 532.06 186.97 Tm (I )Tj EMC ET BT /T1_0 1 Tf 0.0191 Tc 9.9 0 0 9.9 308.14 176.41 Tm (ml/rnin/kg. )Tj 0.05 Tc 9.9723 0 0 9.9 359.43 176.41 Tm (The )Tj 0.22 0.22 0.212 rg 0.0484 Tc 9.9 0 0 9.9 380.66 176.41 Tm (pattern )Tj 0.286 0.286 0.278 rg 0.05 Tc 10.5727 0 0 9.9 416.06 176.41 Tm (of )Tj 0.0387 Tc 9.9 0 0 9.9 429.13 176.41 Tm (breathing )Tj 0.001 Tc 4.556 0 Td (was )Tj 0.0269 Tc 2.023 0 Td (simjlar )Tj 0.0149 Tc 3.352 0 Td (in )Tj 0.025 Tc -22.1 -1.115 Td (both )Tj 0.0174 Tc 2.276 0 Td (tests )Tj 0.0075 Tc 2.183 0 Td (with )Tj 0.05 Tc 10.0889 0 0 9.9 374.39 165.37 Tm (no )Tj 0.0173 Tc 9.9 0 0 9.9 388.18 165.37 Tm (significant )Tj 0.0081 Tc 4.708 0 Td (differences )Tj 0 Tc 4.849 0 Td (i)Tj 0.157 0.157 0.153 rg 0.298 0 Td (n )Tj 0.286 0.286 0.278 rg 0.0134 Tc 0.863 0 Td (frequency )Tj 0.05 Tc 10.5727 0 0 9.9 308.06 154.33 Tm (or )Tj 0 Tc 9.9 0 0 9.9 321.1 154.33 Tm (t)Tj 0.157 0.157 0.153 rg 0.285 0 Td (i)Tj 0.286 0.286 0.278 rg 0.0248 Tc 0.29 0 Td (dal )Tj 0.0173 Tc 1.656 0 Td (volume. )Tj 0.0301 Tc -2.526 -1.115 Td (Individual )Tj 0.0143 Tc 4.66 0 Td (values )Tj 0.05 Tc 10.5727 0 0 9.9 393.02 143.29 Tm (of )Tj 10.5359 0 0 9.9 404.59 143.29 Tm (RHL )Tj 10.0265 0 0 9.9 429.02 143.29 Tm (and )Tj 0.22 0.22 0.212 rg 9.9452 0 0 9.9 448.27 143.29 Tm (RWL )Tj 0.286 0.286 0.278 rg 0.0422 Tc 9.9 0 0 9.9 473.67 143.29 Tm (during )Tj 0.0215 Tc 3.11 0 Td (the )Tj 0.0274 Tc 1.552 0 Td (two )Tj 0.0187 Tc -21.438 -1.067 Td (challenges )Tj 0.05 Tc 9.9087 0 0 9.9 356.54 132.73 Tm (are )Tj 0.0257 Tc 9.9 0 0 9.9 374.9 132.73 Tm (presented )Tj -0.035 Tc 9.2582 0 0 9.9 421.36 132.73 Tm (in )Tj 0.0368 Tc 9.9 0 0 9.9 434.38 132.73 Tm (table )Tj -0.0343 Tc 2.657 0 Td (3. )Tj 0.22 0.22 0.212 rg 0.04 Tc 1.265 0 Td (There )Tj 0.286 0.286 0.278 rg 0.001 Tc 3.062 0 Td (was )Tj 0.22 0.22 0.212 rg 0.05 Tc 10.0889 0 0 9.9 524.63 132.73 Tm (no )Tj 0.286 0.286 0.278 rg 0.0124 Tc 9.9 0 0 9.9 308.02 121.68 Tm (significant )Tj 0.0091 Tc 4.805 0 Td (difference )Tj 0.361 0.361 0.357 rg 0.0149 Tc 4.607 0 Td (in )Tj 0.157 0.157 0.153 rg 0.05 Tc 10.5359 0 0 9.9 414.19 121.68 Tm (RHL )Tj 0.286 0.286 0.278 rg 10.5727 0 0 9.9 441.02 121.68 Tm (or )Tj 0.22 0.22 0.212 rg 9.9452 0 0 9.9 455.47 121.68 Tm (RWL )Tj 0.286 0.286 0.278 rg 0.0126 Tc 9.9 0 0 9.9 483.85 121.68 Tm (between )Tj 0.0215 Tc 3.924 0 Td (the )Tj 0.0027 Tc -21.673 -1.115 Td (tests. )Tj 0.0326 Tc 2.372 0 Td (Expired )Tj 0.05 Tc 10.0881 0 0 9.9 366.62 110.64 Tm (air )Tj 0.0373 Tc 9.9 0 0 9.9 380.62 110.64 Tm (temperature )Tj 0.0252 Tc 5.383 0 Td (was )Tj 0.0423 Tc 1.832 0 Td (found )Tj 0.0496 Tc 2.773 0 Td (to )Tj 0.22 0.22 0.212 rg 0.0363 Tc 1.118 0 Td (be )Tj 0.286 0.286 0.278 rg 0.0155 Tc 1.148 0 Td (slightly, )Tj 0.0451 Tc -19.573 -1.115 Td (but )Tj 0.0164 Tc 1.73 0 Td (significantly, )Tj 0.0169 Tc 5.873 0 Td (lower )Tj 0.22 0.22 0.212 rg 0.05 Tc 9.9334 0 0 9.9 410.31 99.6 Tm (during )Tj 0.286 0.286 0.278 rg 0.0065 Tc 9.9 0 0 9.9 441.97 99.6 Tm (exercise )Tj 0 Tc 3.745 0 Td (b)Tj 0.157 0.157 0.153 rg 0.532 0 Td (u)Tj 0.286 0.286 0.278 rg 0.58 0 Td (t )Tj 0.0031 Tc 0.68 0 Td (we )Tj 0.044 Tc 1.494 0 Td (could )Tj ET endstream endobj 3 0 obj <>stream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endstr endstream endobj 4 0 obj <>stream Hd͊zy8 >sRhF^#y QG#Oç==o/ϧ;c_mӷKv|~_oo~y>}~W=|z>{O݇q~?>Ï?o+~ߒ~;%zΏx߽w;>lp?(O?{wٸ^ PZUuTGu^5P5FjFDMԤU PjVjUmFmک]uPuNNE]E5|| _#_k55|| _#_k55|| _#_k55|| _#_k5Z||-_+_kZ||-_+_kZ||-_+_kZ||-_+_ku:||_'_uu:||_'_uu:||_'_uu:||_'_uz||=_/_z||=_/_z||=_/_z||=_/_ || ߀o77 || ߀o77 || ߀o77 || ߀o77 KG#(~? ?G#(~? ?G#(~? ?G#(~? ?z $߄o77MM&|| $߄o77MM&|| $߄o77MM&|| $߄o77MM&||3,ߌo77f||3,ߌo77f||3,ߌo77f||3,ߌo77f|| "߂oȷ[--|| "߂oȷ[--|| "߂oȷ[--|| "߂oȷ[--||+*ߊoŷʷ[V||+*ߊoŷʷ[V||+*ߊoŷʷ[V||+*ߊoŷʷ[V|| &߆o÷ɷmm6|| &߆o÷ɷmm6|| &߆o÷ɷmm6|| &߆o÷ɷmm6|ۯ\t;]~~߅ww;]~~߅ww;]~~߅ww;]~~߅w߁w;;|C߁w;;|C߁w;;|C߁w;;|C߉w;;NN|'S߉w;;NN|'S߉w;;NN|'S߉w;;NN|'S ߅w]..|K ߅w]..|K ߅w]..|K ߅w]..|?|x>stream jP ftypjp2 jp2 jpxbjpx rreq@ .-jp2hihdrcolrxjp2cOQ)R \#B@HHPHHPHHPHHP((( 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755.29 Tm (the )Tj 0.0283 Tc 1.691 0 Td (fact )Tj 0.05 Tc 9.9231 0 0 9.6 495.34 755.29 Tm (that )Tj 0.0412 Tc 9.6 0 0 9.6 285.1 744.73 Tm (the )Tj 0.05 Tc 9.6202 0 0 9.6 300.46 744.73 Tm (two )Tj 0.0339 Tc 9.6 0 0 9.6 318.63 744.73 Tm (challenges )Tj 0.0378 Tc 4.808 0 Td (were )Tj 0.05 Tc 10.1333 0 0 9.6 387.35 744.73 Tm (not )Tj 0.0286 Tc 9.6 0 0 9.6 404.56 744.73 Tm (identical )Tj 0.0391 Tc 4.05 0 Td (in )Tj 0.0458 Tc 1.156 0 Td (terms )Tj 0.05 Tc 10.5727 0 0 9.6 480.86 744.73 Tm (of )Tj 0.0431 Tc 9.6 0 0 9.6 492.46 744.73 Tm (their )Tj 0.05 Tc 9.6969 0 0 9.6 284.62 733.68 Tm (minute )Tj 0.0385 Tc 9.6 0 0 9.6 317.26 733.68 Tm (ventilation )Tj 0.0362 Tc 5.101 0 Td (response )Tj 0.0196 Tc 4.152 0 Td (profiles. )Tj 0.0448 Tc 3.897 0 Td (As )Tj 0.31 0.314 0.31 rg 0.0168 Tc 1.538 0 Td (seen )Tj 0.239 0.243 0.239 rg 0.0391 Tc 2.206 0 Td (in )Tj 0.0406 Tc 1.256 0 Td (table )Tj 0 Tc -21.554 -1.149 Td (2)Tj 0.404 g 0.541 0 Td (, )Tj 0.239 0.243 0.239 rg 0.0412 Tc 0.764 0 Td (the )Tj 0.05 Tc 9.8695 0 0 9.6 314.9 722.65 Tm (pattern )Tj 10.5727 0 0 9.6 350.3 722.65 Tm (of )Tj 9.6845 0 0 9.6 363.85 722.65 Tm (breathing )Tj 9.9334 0 0 9.6 408.87 722.65 Tm (during )Tj 9.8357 0 0 9.6 442.06 722.65 Tm (the )Tj 0.0447 Tc 9.6 0 0 9.6 460.18 722.65 Tm (steady )Tj 0.05 Tc 9.8216 0 0 9.6 491.86 722.65 Tm (state )Tj 9.6876 0 0 9.6 284.65 712.09 Tm (portions )Tj 11.1292 0 0 9.6 322.93 712.09 Tm (of )Tj 0.0412 Tc 9.6 0 0 9.6 335.02 712.09 Tm (the )Tj 0.0339 Tc 1.593 0 Td (challenges )Tj 0.0378 Tc 4.858 0 Td (were )Tj 0.31 0.314 0.31 rg 0.0411 Tc 2.336 0 Td (sim)Tj 0.114 g 0 Tc 1.606 0 Td (i)Tj 0.239 0.243 0.239 rg 0.0374 Tc 0.3 0 Td (lar. )Tj 0.05 Tc 10.4139 0 0 9.6 454.97 712.09 Tm (It )Tj 0.0001 Tc 9.6 0 0 9.6 465.04 712.09 Tm (is )Tj 0.0498 Tc 1.056 0 Td (true )Tj 0.05 Tc 10.215 0 0 9.6 494.86 712.09 Tm (that )Tj 0.31 0.314 0.31 rg 9.6804 0 0 9.6 284.02 701.05 Tm (steady )Tj 9.8216 0 0 9.6 314.74 701.05 Tm (state )Tj 0.239 0.243 0.239 rg 0.0385 Tc 9.6 0 0 9.6 338.38 701.05 Tm (ventilation )Tj -0.035 Tc 9.3682 0 0 9.6 387.76 701.05 Tm (is )Tj 0.0495 Tc 9.6 0 0 9.6 397.91 701.05 Tm (normally )Tj 0.0303 Tc 4.391 0 Td (achieved )Tj 0.114 g 0 Tc 4.252 0 Td (l)Tj 0.239 0.243 0.239 rg 0.05 Tc 10.2756 0 0 9.6 483.26 701.05 Tm (ater )Tj 0.0391 Tc 9.6 0 0 9.6 503.44 701.05 Tm (in )Tj 0.31 0.314 0.31 rg 0.0186 Tc -22.852 -1.151 Td (exercise, )Tj 0.0325 Tc 4.209 0 Td (whilst )Tj 0.239 0.243 0.239 rg 0.05 Tc 9.765 0 0 9.6 354.63 690 Tm (during )Tj 0.114 g 0 Tc 9.6 0 0 9.6 387.77 690 Tm (I)Tj 0.239 0.243 0.239 rg 0.05 Tc 9.7111 0 0 9.6 391.64 690 Tm (HV )Tj 0.0382 Tc 9.6 0 0 9.6 411.27 690 Tm (challenge, )Tj 0.05 Tc 11.4315 0 0 10.4 458.3 690 Tm (it )Tj 0.0001 Tc 9.6 0 0 9.6 469.84 690 Tm (is )Tj 0.0358 Tc 1.258 0 Td (usually )Tj -0.0015 Tc -20.561 -1.1 Td (fully )Tj 0.0316 Tc 2.252 0 Td (developed )Tj 0.0459 Tc 4.748 0 Td (from )Tj 0.05 Tc 9.8357 0 0 9.6 375.34 679.44 Tm (the )Tj 9.8576 0 0 9.6 391.11 679.44 Tm (onset )Tj 11.1292 0 0 9.6 416.53 679.44 Tm (of )Tj 0.0412 Tc 9.6 0 0 9.6 428.62 679.44 Tm (the )Tj 0.05 Tc 9.6289 0 0 9.6 444.46 679.44 Tm (manoeuvre. )Tj 9.7388 0 0 9.6 497.73 679.44 Tm (We )Tj 0.0388 Tc 9.6 0 0 9.6 284.08 668.41 Tm (instucted )Tj 0.05 Tc 10.5338 0 0 9.6 327.74 668.41 Tm (our )Tj 0.31 0.314 0.31 rg 0.0368 Tc 9.6 0 0 9.6 347.86 668.41 Tm (subjects )Tj 0.05 Tc 10.4772 0 0 9.6 386.85 668.41 Tm (to )Tj 0.239 0.243 0.239 rg 0.035 Tc 9.6 0 0 9.6 401.2 668.41 Tm (increase )Tj 0.0184 Tc 4.156 0 Td (thei)Tj 0.114 g 0 Tc 1.651 0 Td (r )Tj 0.239 0.243 0.239 rg 0.0485 Tc 0.949 0 Td (ventilation )Tj 0.31 0.314 0.31 rg 0.049 Tc -18.956 -1.151 Td (gradually )Tj 0.05 Tc 9.9809 0 0 9.6 326.74 657.36 Tm (so )Tj 0.239 0.243 0.239 rg 9.9203 0 0 9.6 339.26 657.36 Tm (as )Tj 9.8951 0 0 9.6 351.34 657.36 Tm (to )Tj 0.0471 Tc 9.6 0 0 9.6 362.87 657.36 Tm (reach )Tj 0.05 Tc 9.8357 0 0 9.6 388.78 657.36 Tm (the )Tj 0.0323 Tc 9.6 0 0 9.6 405.1 657.36 Tm (ta)Tj 0.114 g 0 Tc 0.851 0 Td (r)Tj 0.239 0.243 0.239 rg 0.0474 Tc 0.393 0 Td (get )Tj 0.0485 Tc 1.606 0 Td (ventilation )Tj 0.0063 Tc 5.094 0 Td (level )Tj 0.05 Tc 10.7518 0 0 9.6 503.41 657.36 Tm (at )Tj 0.0484 Tc 9.6 0 0 9.6 284.15 646.8 Tm (roughly )Tj 0.0412 Tc 3.699 0 Td (the )Tj 0.05 Tc 9.9231 0 0 9.6 334.42 646.8 Tm (same )Tj 0.0428 Tc 9.6 0 0 9.6 358.54 646.8 Tm (time )Tj 0.0291 Tc 2.142 0 Td (as )Tj 0.05 Tc 10.0636 0 0 9.6 389.68 646.8 Tm (in )Tj 0.0431 Tc 9.6 0 0 9.6 400.78 646.8 Tm (their )Tj 0.31 0.314 0.31 rg 0.0284 Tc 2.192 0 Td (exercise )Tj 0.239 0.243 0.239 rg 0.0476 Tc 3.758 0 Td (manoeuvres. )Tj 0.31 0.314 0.31 rg 0.05 Tc 9.803 0 0 9.6 284.12 635.76 Tm (Furthermore, )Tj 0.0433 Tc 9.6 0 0 9.6 344.98 635.76 Tm (since )Tj 0.239 0.243 0.239 rg 0.007 Tc 2.604 0 Td (all )Tj 0.05 Tc 9.7653 0 0 9.6 384.02 635.76 Tm (prev)Tj 0.114 g 0 Tc 9.6 0 0 9.6 403.12 635.76 Tm (i)Tj 0.239 0.243 0.239 rg 0.05 Tc 10.1321 0 0 9.6 405.5 635.76 Tm (ous )Tj 9.7346 0 0 9.6 423.85 635.76 Tm (publications )Tj 0.31 0.314 0.31 rg 10.7518 0 0 9.6 480.85 635.76 Tm (at )Tj 0.239 0.243 0.239 rg 0.0423 Tc 9.6 0 0 9.6 493.43 635.76 Tm (high )Tj 0.31 0.314 0.31 rg 0.0429 Tc -21.801 -1.149 Td (ventilatory )Tj 0.239 0.243 0.239 rg -0.0028 Tc 5.244 0 Td (levels )Tj 0.05 Tc 9.6846 0 0 9.6 361.43 624.73 Tm (have )Tj 9.6492 0 0 9.6 385.3 624.73 Tm (shown )Tj 0.0412 Tc 9.6 0 0 9.6 417.58 624.73 Tm (the )Tj 0.05 Tc 9.6202 0 0 9.6 434.86 624.73 Tm (two )Tj 0.0339 Tc 9.6 0 0 9.6 454.95 624.73 Tm (challenges )Tj 0.31 0.314 0.31 rg 0.05 Tc 9.8951 0 0 9.6 503.02 624.73 Tm (to )Tj 0.114 g 0 Tc 9.6 0 0 9.6 284.15 614.17 Tm (r)Tj 0.239 0.243 0.239 rg 0.0459 Tc 0.341 0 Td (esult )Tj 0.0391 Tc 2.402 0 Td (in )Tj 0.042 Tc 1.194 0 Td (similar )Tj 0.0349 Tc (responses, )Tj 0.31 0.314 0.31 rg 0.0488 Tc 8.205 0 Td (albeit )Tj 0.0412 Tc 2.858 0 Td (the )Tj 0.239 0.243 0.239 rg 0.0182 Tc 1.694 0 Td (likely )Tj 0.05 Tc 9.6487 0 0 9.6 470.38 614.17 Tm (mismatch )Tj -0.0109 Tc 9.6 0 0 9.6 284.08 603.12 Tm (in )Tj 0.0429 Tc 1.106 0 Td (ventilatory )Tj 0.0433 Tc 5.051 0 Td (response )Tj 0.0153 Tc 4.102 0 Td (profiles)Tj 0.404 g 0 Tc 3.233 0 Td (, )Tj 0.239 0.243 0.239 rg -0.0106 Tc 0.515 0 Td (we )Tj 0.05 Tc 10.6052 0 0 9.6 432.38 603.12 Tm (do )Tj 10.1333 0 0 9.6 446.39 603.12 Tm (not )Tj 0.0211 Tc 9.6 0 0 9.6 463.21 603.12 Tm (believe )Tj 0.05 Tc 10.215 0 0 9.6 494.86 603.12 Tm (that )Tj 0.0446 Tc 9.6 0 0 9.6 284.14 592.09 Tm (total )Tj 0.31 0.314 0.31 rg 0.0435 Tc 2.65 0 Td (ventilation )Tj 0.239 0.243 0.239 rg 0.0448 Tc 5.342 0 Td (envelope )Tj 0.05 Tc 9.9334 0 0 9.6 404.07 592.09 Tm (during )Tj 10.3099 0 0 9.6 438.17 592.09 Tm (IHV )Tj 9.6067 0 0 9.6 463.59 592.09 Tm (caused )Tj 0.0412 Tc 9.6 0 0 9.6 498.7 592.09 Tm (the )Tj 0.0306 Tc -22.356 -1.15 Td (increased )Tj 0.05 Tc 9.7938 0 0 9.6 326.3 581.05 Tm (asthmatic )Tj 0.0254 Tc 9.6 0 0 9.6 371.51 581.05 Tm (response. )Tj /T1_1 1 Tf 0.05 Tc 13.9853 0 0 9.3 293.37 570.48 Tm (It )Tj /T1_0 1 Tf -0.035 Tc 9.3682 0 0 9.6 308.08 570.48 Tm (is )Tj 0.0334 Tc 9.6 0 0 9.6 321.61 570.48 Tm (possible )Tj 0.05 Tc 10.215 0 0 9.6 362.38 570.48 Tm (that )Tj 9.8357 0 0 9.6 386.38 570.48 Tm (the )Tj 9.9341 0 0 9.6 405.98 570.48 Tm (attenuated )Tj 0.0433 Tc 9.6 0 0 9.6 458.87 570.48 Tm (response )Tj 0.05 Tc 9.8951 0 0 9.6 503.02 570.48 Tm (to )Tj 0.31 0.314 0.31 rg 0.0213 Tc 9.6 0 0 9.6 283.58 559.44 Tm (exercise )Tj 0.239 0.243 0.239 rg -0.035 Tc 9.3682 0 0 9.6 321.52 559.44 Tm (is )Tj 0.05 Tc 10.0131 0 0 9.6 332.07 559.44 Tm (due )Tj 0.31 0.314 0.31 rg 0.0253 Tc 9.6 0 0 9.6 353.26 559.44 Tm (to )Tj 0.239 0.243 0.239 rg 0.0412 Tc 1.4 0 Td (the )Tj 0.114 g 0 Tc 1.851 0 Td (r)Tj 0.239 0.243 0.239 rg 0.341 0 Td (e)Tj 0.114 g 0.502 0 Td (l)Tj 0.239 0.243 0.239 rg 0.0339 Tc 0.248 0 Td (ease )Tj 0.31 0.314 0.31 rg 0.05 Tc 11.1292 0 0 9.6 417.49 559.44 Tm (of )Tj 9.6872 0 0 9.6 430.94 559.44 Tm (endogeneous )Tj 0.239 0.243 0.239 rg 0.0453 Tc 9.6 0 0 9.6 490.47 559.44 Tm (cate\255)Tj 0.0421 Tc -21.55 -1.149 Td (cholamines, )Tj 0.0349 Tc 5.76 0 Td (being )Tj 0.05 Tc 9.8032 0 0 9.6 365.66 548.41 Tm (absent )Tj 9.765 0 0 9.6 397.83 548.41 Tm (during )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 9.9894 0 0 9.6 430.01 548.41 Tm (IHV. )Tj EMC ET BT /T1_0 1 Tf 0.0497 Tc 9.6 0 0 9.6 456.92 548.41 Tm (However, )Tj 0.05 Tc 9.9203 0 0 9.6 502.46 548.41 Tm (as )Tj 10.0889 0 0 9.6 283.67 537.85 Tm (no )Tj 0.0234 Tc 9.6 0 0 9.6 297.99 537.85 Tm (difference )Tj 0.0391 Tc 4.701 0 Td (in )Tj 0.0412 Tc 1.256 0 Td (the )Tj 0.0433 Tc 1.701 0 Td (response )Tj 0.31 0.314 0.31 rg 0.05 Tc 9.8951 0 0 9.6 412.3 537.85 Tm (to )Tj 0.0213 Tc 9.6 0 0 9.6 424.22 537.85 Tm (exercise )Tj 0.239 0.243 0.239 rg 0.05 Tc 10.5727 0 0 9.6 461.18 537.85 Tm (or )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 10.3099 0 0 10.2 474.17 537.85 Tm (IHV )Tj EMC ET BT /T1_0 1 Tf 9.7473 0 0 9.6 497.27 537.85 Tm (has )Tj 0.0378 Tc 9.6 0 0 9.6 283.69 526.8 Tm (previously )Tj 0.0412 Tc 5.05 0 Td (been )Tj 0.0446 Tc 2.49 0 Td (observed )Tj 0.0465 Tc 4.458 0 Td (when )Tj 0.31 0.314 0.31 rg 0.05 Tc 9.8357 0 0 9.6 425.74 526.8 Tm (the )Tj 0.239 0.243 0.239 rg 0.0339 Tc 9.6 0 0 9.6 443.43 526.8 Tm (challenges )Tj 0.0378 Tc 5.008 0 Td (were )Tj 0.0496 Tc -21.648 -1.15 Td (performed )Tj 0.05 Tc 10.1194 0 0 9.6 331.58 515.76 Tm (at )Tj 9.7341 0 0 9.6 343.12 515.76 Tm (greater )Tj 0.0317 Tc 9.6 0 0 9.6 376.24 515.76 Tm (intensities )Tj 0.31 0.314 0.31 rg -0.0238 Tc 4.784 0 Td ([6, )Tj -0.0254 Tc 1.464 0 Td (7, )Tj 0.239 0.243 0.239 rg -0.0205 Tc 1.226 0 Td (12\), )Tj 0.05 Tc 10.3398 0 0 9.6 465.97 515.76 Tm (and )Tj 9.9203 0 0 9.6 485.66 515.76 Tm (as )Tj 9.8357 0 0 9.6 498.22 515.76 Tm (the )Tj 0.0324 Tc 9.6 0 0 9.6 283.67 504.72 Tm (role )Tj 0.31 0.314 0.31 rg 0.05 Tc 11.1292 0 0 9.6 306.13 504.72 Tm (of )Tj 0.0435 Tc 9.6 0 0 9.6 321.03 504.72 Tm (catecholamines )Tj 0.239 0.243 0.239 rg -0.0109 Tc 7.451 0 Td (in )Tj 0.05 Tc 10.1362 0 0 9.6 406.98 504.72 Tm (EIA )Tj 10.0265 0 0 9.6 431.42 504.72 Tm (and )Tj 10.5475 0 0 9.6 453.55 504.72 Tm (HIA )Tj 0.0001 Tc 9.6 0 0 9.6 479.92 504.72 Tm (is )Tj 0.0098 Tc 1.406 0 Td (very )Tj 0.0463 Tc -21.907 -1.1 Td (controversial )Tj -0.0238 Tc 6.235 0 Td ([4, )Tj -0.0143 Tc 1.59 0 Td (18, )Tj 0.31 0.314 0.31 rg -0.0039 Tc 1.7 0 Td (19], )Tj 0.239 0.243 0.239 rg 0.0394 Tc 2.033 0 Td (we )Tj 0.05 Tc 10.1441 0 0 9.6 409.34 494.16 Tm (do )Tj 10.4827 0 0 9.6 424.79 494.16 Tm (not )Tj 0.0128 Tc 9.6 0 0 9.6 444.01 494.16 Tm (believe )Tj 0.05 Tc 10.5068 0 0 9.6 476.61 494.16 Tm (that )Tj 0.0412 Tc 9.6 0 0 9.6 498.22 494.16 Tm (the )Tj 0.0462 Tc -22.358 -1.15 Td (answer )Tj -0.0069 Tc 3.452 0 Td (lies )Tj 0.05 Tc 10.0636 0 0 9.6 333.04 483.12 Tm (in )Tj 0.0364 Tc 9.6 0 0 9.6 345.1 483.12 Tm (this )Tj 0.0395 Tc 1.95 0 Td (mechanism. )Tj -0.035 Tc 8.8748 0 0 9.6 293.19 472.09 Tm (GELB )Tj 0.31 0.314 0.31 rg /T1_3 1 Tf 0.05 Tc 10.1514 0 0 10 322.47 472.09 Tm (et )Tj 0.239 0.243 0.239 rg -0.0291 Tc 10 0 0 10 337.37 472.09 Tm (a/. )Tj /T1_0 1 Tf -0.035 Tc 9.5041 0 0 10.4 354.97 472.09 Tm ([9] )Tj 0.05 Tc 10.0265 0 0 9.6 372.38 472.09 Tm (and )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 9.4681 0 0 9.6 395.43 472.09 Tm (O'BYRNE )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 10.0265 0 0 9.6 441.5 472.09 Tm (and )Tj /T1_1 1 Tf -0.035 Tc 8.0057 0 0 9.8 464.58 472.09 Tm (JoNES )Tj /T1_0 1 Tf 0 Tc 10.4 0 0 10.4 495.59 472.09 Tm ([)Tj 0.114 g 0.312 0 Td (1)Tj 0.239 0.243 0.239 rg -0.035 Tc 9.3097 0 0 10.4 503.42 472.09 Tm (7] )Tj 0.31 0.314 0.31 rg 0.0355 Tc 9.6 0 0 9.6 283.06 461.05 Tm (suggested )Tj 0.239 0.243 0.239 rg 0 Tc 5.054 0 Td (a )Tj 0.05 Tc 9.7131 0 0 9.6 345.13 461.05 Tm (bronchodilating )Tj 0.0196 Tc 9.6 0 0 9.6 420.86 461.05 Tm (effect )Tj 0.05 Tc 11.1292 0 0 9.6 452.05 461.05 Tm (of )Tj 9.6552 0 0 9.6 468.4 461.05 Tm (inhibitory )Tj 9.6461 0 0 9.6 283.21 450 Tm (prostaglandins )Tj 9.765 0 0 9.6 349.35 450 Tm (during )Tj 0.0186 Tc 9.6 0 0 9.6 380.54 450 Tm (exercise. )Tj 0.0414 Tc 4.043 0 Td (Since )Tj 0.0216 Tc 2.767 0 Td (release )Tj 0.05 Tc 11.1292 0 0 9.6 477.49 450 Tm (of )Tj 0.0251 Tc 9.6 0 0 9.6 490.06 450 Tm (these )Tj 0.05 Tc 9.6343 0 0 9.6 283.18 438.97 Tm (mediators )Tj 0.0001 Tc 9.6 0 0 9.6 329.2 438.97 Tm (is )Tj 0.05 Tc 10.1333 0 0 9.6 339.35 438.97 Tm (not )Tj 0.0181 Tc 9.6 0 0 9.6 357.61 438.97 Tm (believed )Tj 0.05 Tc 9.8951 0 0 9.6 395.98 438.97 Tm (to )Tj 9.8058 0 0 9.6 408.39 438.97 Tm (occur )Tj 10.0636 0 0 9.6 435.76 438.97 Tm (in )Tj 9.7674 0 0 9.6 448.25 438.97 Tm (IHV, )Tj 0.0364 Tc 9.6 0 0 9.6 473.74 438.97 Tm (this )Tj 0.05 Tc 9.7822 0 0 9.6 492.94 438.97 Tm (may )Tj 9.8573 0 0 9.6 282.62 428.41 Tm (contribute )Tj 9.8951 0 0 9.6 330.7 428.41 Tm (to )Tj 0.31 0.314 0.31 rg 9.8357 0 0 9.6 342.7 428.41 Tm (the )Tj 0.239 0.243 0.239 rg 0.0272 Tc 9.6 0 0 9.6 358.95 428.41 Tm (differences )Tj -0.0109 Tc 5.101 0 Td (in )Tj 0.05 Tc 10.194 0 0 9.6 419.42 428.41 Tm (our )Tj 0.0419 Tc 9.6 0 0 9.6 437.62 428.41 Tm (study. )Tj 0.05 Tc 9.7942 0 0 9.6 467.01 428.41 Tm (Whi)Tj 0.114 g 0 Tc 9.6 0 0 9.6 485.2 428.41 Tm (l)Tj 0.239 0.243 0.239 rg 0.248 0 Td (e )Tj 0.0364 Tc 0.858 0 Td (this )Tj 0.0437 Tc -22.147 -1.15 Td (poss)Tj 0.114 g 0 Tc 1.941 0 Td (i)Tj 0.239 0.243 0.239 rg 0.0203 Tc 0.309 0 Td (bility )Tj -0.035 Tc 9.3682 0 0 9.6 331.12 417.37 Tm (is )Tj 0.0448 Tc 9.6 0 0 9.6 342.14 417.37 Tm (attractive, )Tj 0.0412 Tc 4.958 0 Td (tbe )Tj -0.0021 Tc 1.841 0 Td (full )Tj 0.31 0.314 0.31 rg 0.05 Tc 9.707 0 0 9.6 426.14 417.37 Tm (extent )Tj 0.239 0.243 0.239 rg 11.1292 0 0 9.6 456.85 417.37 Tm (of )Tj 0.0412 Tc 9.6 0 0 9.6 470.38 417.37 Tm (the )Tj 0.0406 Tc 1.794 0 Td (inter\255)Tj 0.0442 Tc -21.302 -1.15 Td (action )Tj 0.31 0.314 0.31 rg 0.05 Tc 11.1292 0 0 9.6 314.77 406.33 Tm (of )Tj 0.239 0.243 0.239 rg 0.0486 Tc 9.6 0 0 9.6 329.29 406.33 Tm (prostaglandins, )Tj 0.05 Tc 9.817 0 0 9.6 400.3 406.33 Tm (thromboxanes )Tj 10.0265 0 0 9.6 466.94 406.33 Tm (and )Tj 9.8899 0 0 9.6 488.55 406.33 Tm (other )Tj 9.6343 0 0 9.6 283.18 395.76 Tm (mediators )Tj 10.0636 0 0 9.6 329.2 395.76 Tm (in )Tj 9.8357 0 0 9.6 342.22 395.76 Tm (the )Tj 0.0497 Tc 9.6 0 0 9.6 360.01 395.76 Tm (pathophysiology )Tj 0.05 Tc 11.1292 0 0 9.6 435.25 395.76 Tm (of )Tj 10.1362 0 0 9.6 448.74 395.76 Tm (EIA )Tj 10.0265 0 0 9.6 471.26 395.76 Tm (and )Tj ET BT /Suspect <>BDC 0.114 g /T1_0 1 Tf 0 Tc 9.6 0 0 9.6 491.45 395.76 Tm (I)Tj 0.239 0.243 0.239 rg 0.05 Tc 10.0348 0 0 9.6 495.79 395.76 Tm (HV )Tj EMC ET BT /T1_0 1 Tf 9.6193 0 0 9.6 283.19 384.72 Tm (rema)Tj 0.114 g 0 Tc 9.6 0 0 9.6 304.24 384.72 Tm (i)Tj 0.239 0.243 0.239 rg 0.0143 Tc 0.307 0 Td (ns )Tj 0.05 Tc 9.8951 0 0 9.6 319.18 384.72 Tm (to )Tj 9.7621 0 0 9.6 330.73 384.72 Tm (be )Tj 0.0216 Tc 9.6 0 0 9.6 343.11 384.72 Tm (clarified. )Tj -0.035 Tc 9.1456 0 0 9.6 383 384.72 Tm (MCFADDEN )Tj 0.31 0.314 0.31 rg /T1_3 1 Tf 0.05 Tc 10.1514 0 0 10 435.27 384.72 Tm (et )Tj 0.239 0.243 0.239 rg /T1_2 1 Tf -0.0315 Tc 9.9 0 0 9.9 445.79 384.72 Tm (al. )Tj /T1_0 1 Tf 0 Tc 10.1 0 0 10.1 459.12 384.72 Tm ([)Tj 0.114 g 0.322 0 Td (1)Tj 0.239 0.243 0.239 rg -0.035 Tc 9.199 0 0 10.1 466.52 384.72 Tm (4] )Tj 0.0335 Tc 9.6 0 0 9.6 477.11 384.72 Tm (recently )Tj 0.05 Tc 9.7249 0 0 9.6 282.63 373.69 Tm (demonstrated )Tj 10.215 0 0 9.6 343.66 373.69 Tm (that )Tj 9.8357 0 0 9.6 362.86 373.69 Tm (the )Tj 0.0305 Tc 9.6 0 0 9.6 378.1 373.69 Tm (severity )Tj 0.31 0.314 0.31 rg 0.05 Tc 11.1292 0 0 9.6 412.69 373.69 Tm (of )Tj 0.239 0.243 0.239 rg 10.1362 0 0 9.6 424.26 373.69 Tm (EIA )Tj -0.035 Tc 9.3682 0 0 9.6 444.88 373.69 Tm (is )Tj 0.05 Tc 9.6065 0 0 9.6 453.51 373.69 Tm (dependent )Tj 10.2564 0 0 9.6 499.58 373.69 Tm (on )Tj 0.0412 Tc 9.6 0 0 9.6 283.18 362.65 Tm (the )Tj 0.049 Tc 1.601 0 Td (rapidity )Tj 0.05 Tc 10.3398 0 0 9.6 334.93 362.65 Tm (and )Tj 9.7821 0 0 9.6 353.26 362.65 Tm (magnitude )Tj 11.1292 0 0 9.6 401.17 362.65 Tm (of )Tj 0.0411 Tc 9.6 0 0 9.6 412.7 362.65 Tm (ai)Tj 0.114 g 0 Tc 0.809 0 Td (r)Tj 0.239 0.243 0.239 rg 0.0447 Tc 0.4 0 Td (way )Tj 0.0465 Tc 2.1 0 Td (rewarming )Tj 0.05 Tc 10.0942 0 0 9.6 492.5 362.65 Tm (post )Tj 0.0271 Tc 9.6 0 0 9.6 282.63 351.61 Tm (challenge. )Tj -0.035 Tc 8.4623 0 0 9.6 332.6 351.61 Tm (BAILE )Tj /T1_3 1 Tf 0.0135 Tc 10 0 0 10 363.75 351.61 Tm (et )Tj -0.0291 Tc 1.49 0 Td (a/. )Tj /T1_0 1 Tf -0.035 Tc 9.0515 0 0 10.4 396.26 351.61 Tm ([2] )Tj 0.05 Tc 10.0265 0 0 9.6 413.66 351.61 Tm (and )Tj -0.035 Tc 9.5431 0 0 9.6 437.72 351.61 Tm (McFADDEN )Tj 0.05 Tc 9.7132 0 0 9.6 494.78 351.61 Tm (and )Tj -0.035 Tc 8.8107 0 0 9.6 283.16 340.56 Tm (PrCHURKO )Tj /T1_1 1 Tf 9.0517 0 0 9.7 334.4 340.56 Tm (\(15\) )Tj /T1_0 1 Tf 0.0355 Tc 9.6 0 0 9.6 357.94 340.56 Tm (suggested )Tj 0.05 Tc 9.9231 0 0 9.6 407.5 340.56 Tm (that )Tj 0.0483 Tc 9.6 0 0 9.6 432.97 340.56 Tm (bronchial )Tj 0.05 Tc 10.1435 0 0 9.6 481.82 340.56 Tm (and/or )Tj 9.7607 0 0 9.6 282.74 330 Tm (pulmonary )Tj 0.045 Tc 9.6 0 0 9.6 334.95 330 Tm (circulation )Tj 0.05 Tc 10.0466 0 0 9.6 386.86 330 Tm (may )Tj 9.7621 0 0 9.6 411.37 330 Tm (be )Tj 9.6312 0 0 9.6 426.63 330 Tm (determined )Tj 9.6887 0 0 9.6 480.97 330 Tm (by )Tj 9.8357 0 0 9.6 497.26 330 Tm (the )Tj /T1_1 1 Tf 0.0266 Tc 8.7 0 0 8.7 34.02 294.49 Tm (Table )Tj 0.05 Tc 10.84 0 0 8.7 58.91 294.49 Tm (3.-)Tj 0.0089 Tc 8.7 0 0 8.7 75.6 294.49 Tm (Individual )Tj 0.0192 Tc 4.603 0 Td (values )Tj 0.05 Tc 8.91 0 0 8.7 144.4 294.49 Tm (of )Tj 0.0148 Tc 8.7 0 0 8.7 154.88 294.49 Tm (respiratory )Tj 0.0273 Tc 5.185 0 Td (heat )Tj 0.0053 Tc 2.326 0 Td (and )Tj 0.0242 Tc 1.997 0 Td (water )Tj 0.0156 Tc 2.851 0 Td (los)Tj 0.678 g 0 Tc 1.206 0 Td (.)Tj 0.239 0.243 0.239 rg 0.0048 Tc 0.128 0 Td (ses )Tj 0.0329 Tc 1.875 0 Td (and )Tj 0.05 Tc 8.91 0 0 8.7 307.6 294.49 Tm (of )Tj ET BT /Suspect <>BDC 0.31 0.314 0.31 rg /T1_0 1 Tf 9.1669 0 0 8.7 317.65 294.49 Tm (6FEV)Tj 0 Tc 6.9001 0 0 6.9001 341.52 290.65 Tm (1 )Tj EMC ET BT 0.239 0.243 0.239 rg /T1_1 1 Tf 0.05 Tc 9.1449 0 0 8.7 347.36 294.49 Tm (\(%\)as )Tj 0.0167 Tc 8.7 0 0 8.7 376.15 294.49 Tm (measured )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.0164 Tc 8.7 0 0 8.7 419.0236 294.49 Tm (following )Tj EMC ET BT /T1_1 1 Tf 0.006 Tc 8.7 0 0 8.7 456.7903 294.49 Tm (both )Tj -0.0014 Tc 2.277 0 Td (tests. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0444 Tc 8.7 0 0 8.7 33.5614 271.4437 Tm (PATIENT )Tj EMC ET BT /T1_0 1 Tf 0.0261 Tc 8.7 0 0 8.7 105.5539 271.4437 Tm (EXERC)Tj 0.114 g 0 Tc 3.364 0 Td (I)Tj 0.239 0.243 0.239 rg 0.05 Tc 8.9382 0 0 8.7 138.08 271.44 Tm (SE )Tj 0.0298 Tc 8.7 0 0 8.7 333.56 271.44 Tm (HYPERVENTILATION )Tj -0.035 Tc 9.3822 0 0 10.1 33.59 249.85 Tm (no. )Tj 0.05 Tc 8.9326 0 0 8.7 105.08 249.85 Tm (RHL )Tj 8.9093 0 0 8.7 190.52 249.37 Tm (RWL )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 8.9759 0 0 8.7 261.97 249.85 Tm (6FEV)Tj /T1_1 1 Tf 0 Tc 5.5001 0 0 5.5001 284.95 246.01 Tm (1 )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.7036 0 0 8.7 333.56 249.37 Tm (RHL )Tj 8.7021 0 0 8.7 405.08 249.85 Tm (RWL )Tj ET BT /Suspect <>BDC 0.31 0.314 0.31 rg /T1_0 1 Tf 8.785 0 0 8.7 454.93 249.85 Tm (6FEV)Tj 0 Tc 6.2 0 0 6.2 477.87 246.49 Tm (1 )Tj EMC ET BT 0.239 0.243 0.239 rg /T1_0 1 Tf 0.0212 Tc 8.7 0 0 8.7 98.86 237.85 Tm (kcal/min )Tj 0.0324 Tc 10.256 -0.055 Td (gm/min )Tj /T1_1 1 Tf 0 Tc 9.039 0.055 Td (% )Tj /T1_0 1 Tf -0.0033 Tc 6.856 -0.055 Td (kcaVmin )Tj 0.0324 Tc 8.601 0 Td (gm/min )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 8.7 0 0 8.7 462.6244 237.85 Tm (% )Tj EMC ET BT /T1_0 1 Tf 9.3 0 0 9.3 33.76 214.8 Tm (1 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 8.7 0 0 8.7 104.55 214.8 Tm (0)Tj 0.114 g 0.597 0 Td (.)Tj 0.239 0.243 0.239 rg 0.0273 Tc 0.228 0 Td (58 )Tj EMC /Suspect <>BDC 0.31 0.314 0.31 rg 0.0308 Tc 9.052 0 Td (0.67 )Tj EMC ET BT 0.239 0.243 0.239 rg /T1_0 1 Tf 0 Tc 8.7 0 0 8.7 266.37 214.8 Tm (4 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0124 Tc 8.7 0 0 8.7 333.0381 214.8 Tm (0.65 )Tj EMC /Suspect <>BDC 8.276 0 Td (0.74 )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.845 0 0 8.7 462.19 214.8 Tm (24 )Tj 0 Tc 8.7 0 0 8.7 33.07 203.76 Tm (2 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0308 Tc 8.7 0 0 8.7 104.5492 203.76 Tm (0.70 )Tj EMC /Suspect <>BDC 9.876 0 Td (0.80 )Tj EMC ET BT /T1_0 1 Tf 0.0093 Tc 8.7 0 0 8.7 262.2628 203.2902 Tm (15 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0244 Tc 8.7 0 0 8.7 333.0286 203.76 Tm (0.71 )Tj EMC /Suspect <>BDC 0.0124 Tc 8.221 0 Td (0.81 )Tj EMC ET BT /T1_0 1 Tf 0.012 Tc 8.7 0 0 8.7 462.1888 203.76 Tm (24 )Tj 0.31 0.314 0.31 rg 0 Tc -49.33 -1.268 Td (3 )Tj -0.0262 Tc 9 0 0 9 104.81 192.73 Tm (1.21 )Tj -0.0078 Tc 8.7 0 0 8.7 191.22 192.73 Tm (1.38 )Tj 0.239 0.243 0.239 rg 0.05 Tc 8.845 0 0 8.7 261.55 192.25 Tm (29 )Tj /T1_1 1 Tf -0.0037 Tc 7.8001 0 0 7.8001 333.83 192.73 Tm (1.24 )Tj /T1_0 1 Tf -0.0262 Tc 8.7 0 0 8.7 405.78 192.73 Tm (1.41 )Tj 0.05 Tc 8.845 0 0 8.7 461.71 192.73 Tm (25 )Tj 0 Tc 8.7 0 0 8.7 32.6 181.69 Tm (4 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0124 Tc 8.7 0 0 8.7 104.549 181.69 Tm (0.68 )Tj EMC /Suspect <>BDC 9.876 0 Td (0.77 )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 9.0021 0 0 8.7 261.5 181.69 Tm (34 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0124 Tc 8.7 0 0 8.7 333.03 181.69 Tm (0.68 )Tj EMC /Suspect <>BDC 0 Tc 8.221 0.054 Td (0)Tj 0.114 g 0.541 0 Td (.)Tj 0.31 0.314 0.31 rg 0.05 Tc 8.8942 0 0 8.7 411.27 182.16 Tm (78 )Tj EMC ET BT 0.239 0.243 0.239 rg /T1_0 1 Tf 8.8142 0 0 8.7 461.72 181.69 Tm (44 )Tj /T1_3 1 Tf 0 Tc 10 0 0 10 32.54 170.16 Tm (5 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0308 Tc 8.7 0 0 8.7 104.07 170.65 Tm (0.76 )Tj EMC /Suspect <>BDC 0.0124 Tc 9.931 0 Td (0.87 )Tj EMC ET BT /T1_1 1 Tf 0 Tc 8.4 0 0 8.4 266.61 170.16 Tm (1 )Tj ET BT /Suspect <>BDC 0.31 0.314 0.31 rg /T1_0 1 Tf 0.0308 Tc 8.7 0 0 8.7 332.55 170.65 Tm (0.83 )Tj EMC /Suspect <>BDC 0.239 0.243 0.239 rg 0.0124 Tc 8.276 0 Td (0.95 )Tj EMC ET BT /T1_0 1 Tf -0.035 Tc 8.5945 0 0 8.7 462.42 170.65 Tm (18 )Tj 0 Tc 8.7 0 0 8.7 33.01 159.61 Tm (6 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0308 Tc 8.7 0 0 8.7 104.0716 159.61 Tm (0.56 )Tj EMC /Suspect <>BDC 9.876 0 Td (0.67 )Tj EMC /Suspect <>BDC 0.31 0.314 0.31 rg 0.05 Tc 8.829 0 0 8.7 261.77 159.61 Tm (10 )Tj EMC /Suspect <>BDC 0.239 0.243 0.239 rg 0.0124 Tc 8.7 0 0 8.7 333.03 159.61 Tm (0.56 )Tj EMC /Suspect <>BDC 0.0308 Tc 8.221 0.055 Td (0.64 )Tj EMC ET BT /T1_0 1 Tf 0.012 Tc 8.7 0 0 8.7 461.7117 160.0885 Tm (25 )Tj 0 Tc -49.329 -1.269 Td (7 )Tj 0.0106 Tc 8.252 -0.055 Td (1.18 )Tj -0.0078 Tc 9.931 0 Td (1.35 )Tj -0.035 Tc 8.0574 0 0 8.7 262.28 148.57 Tm (11 )Tj -0.0084 Tc 9 0 0 9 333.29 149.05 Tm (1.12 )Tj 0.31 0.314 0.31 rg 0.0106 Tc 8.7 0 0 8.7 405.3 149.05 Tm (1.29 )Tj ET BT /Suspect <>BDC 0.239 0.243 0.239 rg /T1_0 1 Tf 0.05 Tc 9.0021 0 0 8.7 461.66 149.05 Tm (30 )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.7 0 0 8.7 32.49 137.52 Tm (8 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0124 Tc 8.7 0 0 8.7 104.0736 138.0072 Tm (0.59 )Tj EMC /Suspect <>BDC 9.876 0 Td (0.67 )Tj EMC ET BT /T1_0 1 Tf -0.035 Tc 8.5945 0 0 9 262.26 137.52 Tm (12 )Tj ET BT /Suspect <>BDC 0.31 0.314 0.31 rg /T1_0 1 Tf -0.0244 Tc 8.7 0 0 8.7 332.55 138.01 Tm (0.71 )Tj EMC /Suspect <>BDC 0.239 0.243 0.239 rg 0.0124 Tc 8.276 0 Td (0.83 )Tj EMC ET BT /T1_0 1 Tf 0.012 Tc 8.7 0 0 8.7 461.7102 138.01 Tm (25 )Tj 0.05 Tc 8.7474 0 0 8.7 32.12 115.93 Tm (Mean )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0308 Tc 8.7 0 0 8.7 103.59 115.93 Tm (0.78 )Tj EMC /Suspect <>BDC 0.0492 Tc 9.876 0 Td (0.90 )Tj EMC ET BT /T1_0 1 Tf 0.0093 Tc 8.7 0 0 8.7 261.3036 115.93 Tm (15 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.006 Tc 8.7 0 0 8.7 332.5566 115.93 Tm (0.81 )Tj EMC /Suspect <>BDC 0 Tc 8.276 0.054 Td (0)Tj 0.404 g 0.0098 Tc 0.541 0 Td (.9)Tj 0.239 0.243 0.239 rg 0 Tc 0.726 0 Td (3 )Tj EMC ET BT /T1_0 1 Tf 0.012 Tc 8.7 0 0 8.7 461.7081 116.3998 Tm (27 )Tj -0.035 Tc 8.6719 0 0 9.6 31.67 104.4 Tm (\261sEM )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0308 Tc 8.7 0 0 8.7 103.59 104.89 Tm (0.09 )Tj EMC /Suspect <>BDC 0.0124 Tc 9.876 0 Td (0.11 )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.7 0 0 8.7 265.4013 104.89 Tm (4 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0124 Tc 8.7 0 0 8.7 332.5479 104.89 Tm (0.09 )Tj EMC /Suspect <>BDC 0.0308 Tc 8.276 0.054 Td (0.10 )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.7 0 0 8.7 465.9798 105.3598 Tm (3 )Tj ET endstream endobj 30 0 obj <>stream jP ftypjp2 jp2 jpxbjpx rreq@ --jp2hihdrcolr,Ijp2cOQ/R \#B@HHPHHPHHPHHP((( ߇M Np>•ct ^q7mA $%ShMm%aJIP+K ذ\'[e!)Yry 7nǗlI+ma䚌zdos \$%8Q}v PqU|Z ]a٤sx̄KUtO d9 B bS]O38Q#5o/E7:j1~Ds s)F3AWq 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0.353 0.349 rg 0.05 Tc 11.1292 0 0 9.7 213.01 657.36 Tm (of )Tj 0.29 0.294 0.286 rg 0.0335 Tc 9.7 0 0 9.7 224.06 657.36 Tm (exerc)Tj 0.188 0.188 0.18 rg 0 Tc 2.278 0 Td (i)Tj 0.29 0.294 0.286 rg -0.015 Tc 0.291 0 Td (se )Tj 0.353 0.353 0.349 rg 0.05 Tc 10.0265 0 0 9.7 259.58 657.36 Tm (and )Tj 11.1292 0 0 9.7 277.81 657.36 Tm (of )Tj 0.188 0.188 0.18 rg 0 Tc 9.7 0 0 9.7 60.89 646.33 Tm (I)Tj 0.29 0.294 0.286 rg 0.05 Tc 10.0348 0 0 9.7 64.75 646.33 Tm (HV )Tj 0.0342 Tc 9.7 0 0 9.7 85.43 646.33 Tm (where )Tj 0.0311 Tc 3.215 0 Td (this )Tj 0.05 Tc 9.7228 0 0 9.7 137.66 646.33 Tm (attenuated )Tj 0.353 0.353 0.349 rg 0.0307 Tc 9.7 0 0 9.7 188.63 646.33 Tm (response )Tj 0.29 0.294 0.286 rg 0.017 Tc 4.355 0 Td (was )Tj 0.05 Tc 9.7838 0 0 9.7 252.95 646.33 Tm (not )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 10.2564 0 0 9.7 272.54 646.33 Tm (ob)Tj 0.451 0.451 0.447 rg 0 Tc 9.7 0 0 9.7 283.57 646.33 Tm (\255)Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0227 Tc 9.7 0 0 9.7 60.3439 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Td (would )Tj 0.05 Tc 10.1333 0 0 9.7 272.63 624.73 Tm (not )Tj 0.0168 Tc 9.7 0 0 9.7 60.47 613.68 Tm (necessarily )Tj 0.05 Tc 9.7621 0 0 9.7 108.97 613.68 Tm (be )Tj 9.9102 0 0 9.7 122.3 613.68 Tm (apparent )Tj 10.7518 0 0 9.7 163.09 613.68 Tm (at )Tj 0.0193 Tc 9.7 0 0 9.7 175.19 613.68 Tm (high )Tj 0.188 0.188 0.18 rg 0 Tc 2.22 0 Td (l)Tj 0.353 0.353 0.349 rg 0.0115 Tc 0.245 0 Td (evels )Tj 0.29 0.294 0.286 rg 0.05 Tc 11.1292 0 0 9.7 222.61 613.68 Tm (of )Tj 0.0092 Tc 9.7 0 0 9.7 234.62 613.68 Tm (exercise )Tj 0.05 Tc 10.0265 0 0 9.7 270.62 613.68 Tm (and )Tj 0.188 0.188 0.18 rg 0 Tc 9.7 0 0 9.7 60.47 603.12 Tm (h)Tj 0.29 0.294 0.286 rg 0.544 0 Td (y)Tj 0.188 0.188 0.18 rg 0.546 0 Td (p)Tj 0.29 0.294 0.286 rg 0.0318 Tc 0.533 0 Td (erventilation. )Tj 0.188 0.188 0.18 rg 0 Tc -0.64 -1.137 Td (I)Tj 0.29 0.294 0.286 rg 0.452 0 Td (n )Tj 0.034 Tc 1.13 0 Td (conclusion, )Tj 0.0345 Tc 5.648 0 Td (the )Tj 0.188 0.188 0.18 rg 0 Tc 1.98 0 Td (r)Tj 0.29 0.294 0.286 rg 0.0339 Tc 0.337 0 Td (esults )Tj 0.05 Tc 11.1292 0 0 9.7 192.37 592.09 Tm (of )Tj 0.0345 Tc 9.7 0 0 9.7 207.82 592.09 Tm (the )Tj 0.0403 Tc 1.982 0 Td (present )Tj 0.0463 Tc 3.745 0 Td (study )Tj 0.353 0.353 0.349 rg 0.0241 Tc -20.981 -1.138 Td (suggest )Tj 0.29 0.294 0.286 rg 0.05 Tc 9.9231 0 0 9.7 95.02 581.05 Tm (that )Tj 0.0172 Tc 9.7 0 0 9.7 115.67 581.05 Tm (whilst )Tj 0.0065 Tc 3.011 0 Td (it )Tj -0.0066 Tc 0.99 0 Td (is )Tj 0.0351 Tc 1.098 0 Td (possib)Tj 0.188 0.188 0.18 rg 0 Tc 2.762 0 Td (l)Tj 0.353 0.353 0.349 rg 0.245 0 Td (e )Tj 0.05 Tc 10.215 0 0 9.7 203.02 581.05 Tm (that )Tj 0.29 0.294 0.286 rg 0.0345 Tc 9.7 0 0 9.7 224.14 581.05 Tm (the )Tj 0.0228 Tc 1.726 0 Td (increase )Tj -0.035 Tc 9.2582 0 0 9.7 278.8 581.05 Tm (in )Tj 0.0027 Tc 9.7 0 0 9.7 60.46 570 Tm (ve)Tj 0.188 0.188 0.18 rg 0 Tc 0.941 0 Td (n)Tj 0.29 0.294 0.286 rg 0.0346 Tc 0.593 0 Td (tilation )Tj 0.05 Tc 9.765 0 0 9.7 109.35 570 Tm (during )Tj 0.0162 Tc 9.7 0 0 9.7 141.02 570 Tm (exercise )Tj 0.0472 Tc 3.761 0 Td (acts )Tj 0.353 0.353 0.349 rg 0.05 Tc 9.9203 0 0 9.7 197.66 570 Tm (as )Tj 0.29 0.294 0.286 rg 0 Tc 9.7 0 0 9.7 210.62 570 Tm (a )Tj 0.0225 Tc 0.948 0 Td (trigger, )Tj 0.0092 Tc 3.505 0 Td (exercise )Tj /T1_2 1 Tf -0.0281 Tc 10.7 0 0 10.7 59.4 559.44 Tm (per )Tj -0.035 Tc 10.3012 0 0 10.7 76.35 559.44 Tm (se )Tj /T1_0 1 Tf 0.05 Tc 9.89 0 0 9.7 87.76 559.44 Tm (introd)Tj 0.188 0.188 0.18 rg 0 Tc 9.7 0 0 9.7 114.24 559.44 Tm (u)Tj 0.29 0.294 0.286 rg -0.0089 Tc 0.535 0 Td (ces )Tj 0.05 Tc 9.7766 0 0 9.7 135.26 559.44 Tm (an )Tj 9.7453 0 0 9.7 148.7 559.44 Tm (additional )Tj 0.045 Tc 9.7 0 0 9.7 195.73 559.44 Tm (factor )Tj 0.0215 Tc 2.93 0 Td (which )Tj 0.05 Tc 9.7822 0 0 9.7 252.46 559.44 Tm (may )Tj 0.353 0.353 0.349 rg 9.9685 0 0 9.7 273.5 559.44 Tm (act )Tj 0.0171 Tc 9.7 0 0 9.7 60.46 548.41 Tm (to )Tj 0.29 0.294 0.286 rg 0.015 Tc 1.231 0 Td (limit )Tj 0.353 0.353 0.349 rg 0.0345 Tc 2.332 0 Td (the )Tj 0.29 0.294 0.286 rg 0.0096 Tc 1.673 0 Td (full )Tj 0.0307 Tc 1.841 0 Td (response )Tj 0.0318 Tc 4.099 0 Td (observed )Tj 0.0253 Tc 4.254 0 Td (following )Tj 0.0385 Tc 4.458 0 Td (IHV. )Tj 0.188 0.188 0.18 rg 0 Tc 8.7 0 0 8.7 153.08 516.73 Tm (R)Tj 0.29 0.294 0.286 rg 0.0349 Tc 0.656 0 Td (efe)Tj 0.188 0.188 0.18 rg 0 Tc 1.278 0 Td (r)Tj 0.29 0.294 0.286 rg 0.377 0 Td (e)Tj 0.188 0.188 0.18 rg 0.451 0 Td (n)Tj 0.29 0.294 0.286 rg 0.007 Tc 0.544 0 Td (ces )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf -0.035 Tc 8.1 0 0 8.1 60.9 500.41 Tm (I. )Tj EMC ET BT /T1_0 1 Tf 0.0212 Tc 8.1 0 0 8.1 73.9086 500.41 Tm (Anderson )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0236 Tc 8.1 0 0 8.1 109.7673 500.41 Tm (SO. )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 126.1455 500.41 Tm (-)Tj 0.0121 Tc 0.893 0 Td (Issues )Tj 0.29 0.294 0.286 rg -0.035 Tc 7.9356 0 0 8.1 156.9 500.41 Tm (in )Tj 0.353 0.353 0.349 rg 0.0011 Tc 8.1 0 0 8.1 165.99 500.41 Tm (exercise )Tj 0.29 0.294 0.286 rg 0.0187 Tc 3.617 0 Td (induced )Tj 0.022 Tc 3.673 0 Td (asthma. )Tj 0.353 0.353 0.349 rg /T1_3 1 Tf 0 Tc 8 0 0 8 254.81 500.41 Tm (J )Tj /T1_2 1 Tf -0.0012 Tc 8.2 0 0 8.2 262.21 500.41 Tm (Allergy )Tj -0.0239 Tc -24.679 -1.113 Td (Clin )Tj 0.29 0.294 0.286 rg -0.0124 Tc 2.021 0 Td (Jmmunol )Tj 0.353 0.353 0.349 rg /T1_0 1 Tf -0.035 Tc 8.0056 0 0 8.1 109.16 491.28 Tm (1985, )Tj 0.29 0.294 0.286 rg -0.0201 Tc 8.1 0 0 8.1 129.03 491.28 Tm (76, )Tj 0.0165 Tc 1.6 0 Td (763-772. )Tj 0.353 0.353 0.349 rg -0.02 Tc -10.188 -1.126 Td (2. )Tj 0.29 0.294 0.286 rg -0.0026 Tc 1.779 0 Td (Baile )Tj 0.05 Tc 8.104 0 0 8.1 92.6 482.16 Tm (EM, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0298 Tc 8.1 0 0 8.1 109.88 482.16 Tm (Dahl )Tj EMC ET BT /T1_0 1 Tf 0.017 Tc 8.1 0 0 8.1 126.728 482.16 Tm (by )Tj 0.0198 Tc 1.298 0 Td (RW, )Tj -0.0135 Tc 2.194 0 Td (Wiggs )Tj 0.0198 Tc 2.843 0 Td (BR, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0455 Tc 8.1 0 0 8.1 193.3991 482.16 Tm (Pare )Tj EMC /Suspect <>BDC 0.05 Tc 8.7762 0 0 8.1 210.2 482.16 Tm (PD)Tj 0.188 0.188 0.18 rg 0 Tc 8.1 0 0 8.1 222.07 482.16 Tm (.)Tj 0.451 0.451 0.447 rg 0.425 0 Td (-)Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0042 Tc 8.1 0 0 8.1 232.762 482.16 Tm (Role )Tj 0.05 Tc 8.9033 0 0 8.1 250 482.16 Tm (of )Tj 0.0147 Tc 8.1 0 0 8.1 259.18 482.16 Tm (tracheal )Tj 0.05 Tc 8.1466 0 0 8.1 59.44 473.53 Tm (and )Tj 0.0185 Tc 8.1 0 0 8.1 76.81 473.53 Tm (bronchial )Tj 0.0097 Tc 4.433 0 Td (circu)Tj 0.188 0.188 0.18 rg 0 Tc 2.075 0 Td (l)Tj 0.29 0.294 0.286 rg 0.0368 Tc 0.236 0 Td (ation )Tj 0.188 0.188 0.18 rg 0 Tc 2.727 0 Td (i)Tj 0.29 0.294 0.286 rg 0.304 0 Td (n )Tj 0.0235 Tc 1.067 0 Td (respiratory )Tj 0.0198 Tc 5.096 0 Td (heat )Tj 0.0034 Tc 2.301 0 Td (exchange. )Tj /T1_3 1 Tf 0 Tc 8 0 0 8 262.01 473.53 Tm (J )Tj /T1_2 1 Tf 0.036 Tc 8.2 0 0 8.2 270.37 473.53 Tm (Appl )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.0136 Tc 8.2 0 0 8.2 60.0564 464.4116 Tm (Physiol, )Tj EMC ET BT /T1_0 1 Tf -0.0261 Tc 8.1 0 0 8.1 89.48 464.41 Tm (1985, )Tj 0.0143 Tc 2.451 0 Td (58, )Tj -0.0294 Tc 1.607 0 Td (217)Tj 0.647 0.647 0.635 rg 0 Tc 1.417 0 Td (-)Tj 0.29 0.294 0.286 rg -0.0294 Tc 0.598 0 Td (222)Tj 0.451 0.451 0.447 rg 0 Tc 1.526 0 Td (. )Tj 0.353 0.353 0.349 rg -11.309 -1.068 Td (3)Tj 0.188 0.188 0.18 rg 0.523 0 Td (. )Tj 0.29 0.294 0.286 rg 0.0081 Tc 1.26 0 Td (Bar-)Tj 0.0042 Tc 1.839 0 Td (Yishay )Tj 0.0417 Tc 3.138 0 Td (E, )Tj 0.05 Tc 8.4881 0 0 8.1 123.28 455.76 Tm (Gur )Tj 0.0243 Tc 8.1 0 0 8.1 139.14 455.76 Tm (I, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 146.8188 455.76 Tm (I )Tj EMC ET BT /T1_0 1 Tf 0.0412 Tc 8.1 0 0 8.1 149.751 455.76 Tm (nbar )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 10.4831 0 0 8.1 166.93 455.76 Tm (0, )Tj EMC ET BT /T1_0 1 Tf 0.0341 Tc 8.1 0 0 8.1 177.64 455.76 Tm (Neuman )Tj 0.0243 Tc 3.84 0 Td (I, )Tj 0 Tc 0.886 0 Td (O)Tj 0.188 0.188 0.18 rg 0.772 0 Td (l)Tj 0.353 0.353 0.349 rg -0.035 Tc 7.9356 0 0 8.1 224.58 455.76 Tm (in )Tj 0.29 0.294 0.286 rg 0.0118 Tc 8.1 0 0 8.1 233.24 455.76 Tm (RA, )Tj 0.0202 Tc 2.01 0 Td (Godfrey )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 279.2075 455.76 Tm (S)Tj 0.451 0.451 0.447 rg 0.59 0 Td (. )Tj EMC ET BT 0.561 0.561 0.553 rg /T1_0 1 Tf 8.1 0 0 8.1 59.4302 446.6475 Tm (-)Tj 0.29 0.294 0.286 rg -0.0051 Tc 0.836 0 Td (Difference )Tj 0 Tc 4.51 0 Td (between )Tj 0.353 0.353 0.349 rg -0.0191 Tc 3.541 0 Td (sw)Tj 0.188 0.188 0.18 rg 0 Tc 1.131 0 Td (i)Tj 0.29 0.294 0.286 rg 0.0193 Tc 0.302 0 Td (mming )Tj 0.353 0.353 0.349 rg 0.05 Tc 8.1466 0 0 8.1 167.92 446.65 Tm (and )Tj 0.29 0.294 0.286 rg 0.0348 Tc 8.1 0 0 8.1 182.87 446.65 Tm (runnjng )Tj 0.353 0.353 0.349 rg 0.05 Tc 8.2669 0 0 8.1 211.12 446.65 Tm (as )Tj 0.0061 Tc 8.1 0 0 8.1 220.21 446.65 Tm (stimuli )Tj 0.29 0.294 0.286 rg 0 Tc 3.143 0 Td (for )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0011 Tc 8.1 0 0 8.1 256.7086 446.65 Tm (exercise)Tj 0.188 0.188 0.18 rg 0 Tc 3.319 0 Td (\255)Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0089 Tc 8.1 0 0 8.1 59.4493 437.5294 Tm (induced )Tj 0.353 0.353 0.349 rg 0.022 Tc 3.614 0 Td (asthma. )Tj 0.29 0.294 0.286 rg /T1_2 1 Tf -0.0243 Tc 8.2 0 0 8.2 118.62 437.53 Tm (Eur )Tj /T1_3 1 Tf 0 Tc 8 0 0 8 132.89 437.53 Tm (J )Tj /T1_2 1 Tf 0.036 Tc 8.2 0 0 8.2 139.81 437.53 Tm (Appl )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.0136 Tc 8.2 0 0 8.2 158.4568 437.53 Tm (Physiol, )Tj EMC ET BT /T1_0 1 Tf -0.0261 Tc 8.1 0 0 8.1 188.36 437.53 Tm (1982, )Tj 0.353 0.353 0.349 rg -0.035 Tc 8.0868 0 0 8.1 208.29 437.53 Tm (48)Tj 0.451 0.451 0.447 rg 0 Tc 8.1 0 0 8.1 216.35 437.53 Tm (, )Tj 0.353 0.353 0.349 rg -0.0204 Tc 0.598 0 Td (387)Tj 0.451 0.451 0.447 rg 0 Tc 1.481 0 Td (-)Tj 0.353 0.353 0.349 rg -0.0179 Tc 0.533 0 Td (397. )Tj 0.29 0.294 0.286 rg -0.0236 Tc -22.037 -1.067 Td (4. )Tj 0.0066 Tc 1.836 0 Td (Barnes )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0028 Tc 8.1 0 0 8.1 98.8352 428.8873 Tm (PJ. )Tj EMC ET BT /T1_0 1 Tf -0.0082 Tc 8.1 0 0 8.1 111.3173 428.8873 Tm (Brown )Tj 0.353 0.353 0.349 rg 0.0116 Tc 3.022 0 Td (MJ, )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0096 Tc 8.1 0 0 8.1 150.5618 428.8873 Tm (Silverman )Tj EMC ET BT /T1_0 1 Tf -0.0025 Tc 8.1 0 0 8.1 187.1495 428.8873 Tm (M, )Tj 0.0077 Tc 1.481 0 Td (Dollcry )Tj 0.05 Tc 9.6609 0 0 8.1 226.46 428.89 Tm (CT.-)Tj 0.353 0.353 0.349 rg 0.0269 Tc 8.1 0 0 8.1 247.6 428.89 Tm (Circulating )Tj 0.29 0.294 0.286 rg 0.0204 Tc -23.289 -1.127 Td (catecholamines )Tj 0.0095 Tc 6.816 0 Td (in )Tj -0.0073 Tc 1.242 0 Td (exercise )Tj 0.353 0.353 0.349 rg 0.05 Tc 8.1466 0 0 8.1 154 419.76 Tm (and )Tj 0.0181 Tc 8.1 0 0 8.1 170.87 419.76 Tm (hyperventilation)Tj 0.188 0.188 0.18 rg 0 Tc 6.864 0 Td (-)Tj 0.353 0.353 0.349 rg 0.0187 Tc 0.299 0 Td (induced )Tj 0.0319 Tc 3.732 0 Td (asthma. )Tj /T1_2 1 Tf 0.0027 Tc 8.2 0 0 8.2 59.35 411.12 Tm (Thorax, )Tj /T1_0 1 Tf -0.035 Tc 8.0056 0 0 8.1 89.48 411.12 Tm (1981, )Tj -0.014 Tc 8.1 0 0 8.1 109.35 411.12 Tm (36, )Tj 0.29 0.294 0.286 rg -0.0016 Tc 1.548 0 Td (435)Tj 0.451 0.451 0.447 rg 0 Tc 1.474 0 Td (-)Tj 0.29 0.294 0.286 rg -0.0054 Tc 0.541 0 Td (440. )Tj 0.353 0.353 0.349 rg -0.0047 Tc -9.788 -1.184 Td (5. )Tj 0.29 0.294 0.286 rg 0.0063 Tc 1.727 0 Td (Ben )Tj 0.0362 Tc 2.193 0 Td (Dov )Tj 0 Tc 2.309 0 Td (I)Tj 0.451 0.451 0.447 rg 0.347 0 Td (, )Tj 0.29 0.294 0.286 rg 0.0108 Tc 0.781 0 Td (Bar-Yishay )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf -0.035 Tc 7.6834 0 0 8.1 161.24 401.53 Tm (E, )Tj EMC ET BT /T1_0 1 Tf 0.0301 Tc 8.1 0 0 8.1 171.76 401.53 Tm (Godfrey )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 204.3301 401.53 Tm (S)Tj 0.451 0.451 0.447 rg 0.59 0 Td (. )Tj EMC ET BT 0.765 0.765 0.753 rg /T1_0 1 Tf 8.1 0 0 8.1 214.9492 401.53 Tm (-)Tj 0.29 0.294 0.286 rg 0.0195 Tc 1.073 0 Td (Refractory )Tj 0.353 0.353 0.349 rg 0.0127 Tc 4.984 0 Td (period )Tj 0.29 0.294 0.286 rg 0.0081 Tc -25.316 -1.126 Td (following )Tj 0.0063 Tc 4.504 0 Td (exercised-induced )Tj 0.029 Tc 8.001 0 Td (asthma )Tj 0.353 0.353 0.349 rg 0.0155 Tc 3.625 0 Td (unexplained )Tj 0.017 Tc 5.69 0 Td (by )Tj 0.0235 Tc 1.598 0 Td (respiratory )Tj 0.29 0.294 0.286 rg 0.0198 Tc -23.407 -1.068 Td (heat )Tj -0.0178 Tc 2.126 0 Td (loss. )Tj /T1_2 1 Tf 0.05 Tc 8.3646 0 0 8.2 93.73 383.76 Tm (Am )Tj 0.0437 Tc 8.2 0 0 8.2 108.06 383.76 Tm (Rev )Tj 0.0058 Tc 1.873 0 Td (Respir )Tj -0.0204 Tc 2.988 0 Td (Dis, )Tj /T1_0 1 Tf -0.0305 Tc 8.1 0 0 8.1 164.36 383.76 Tm (1982)Tj 0.451 0.451 0.447 rg 0 Tc 1.915 0 Td (, )Tj 0.29 0.294 0.286 rg -0.035 Tc 7.9309 0 0 8.1 185.49 383.76 Tm (125, )Tj 0.353 0.353 0.349 rg 0.0078 Tc 8.1 0 0 8.1 201.01 383.76 Tm (530)Tj 0.561 0.561 0.553 rg 0 Tc 1.543 0 Td (-)Tj 0.353 0.353 0.349 rg -0.0218 Tc 0.531 0 Td (534)Tj 0.451 0.451 0.447 rg 0 Tc 1.533 0 Td (. )Tj 0.353 0.353 0.349 rg -0.035 Tc 7.6478 0 0 8.1 58.95 374.65 Tm (6. )Tj 0.29 0.294 0.286 rg -0.0233 Tc 8.1 0 0 8.1 73.4 374.65 Tm (Ben )Tj 0.0362 Tc 2.074 0 Td (Dov )Tj 0.188 0.188 0.18 rg 0 Tc 2.309 0 Td (I)Tj 0.29 0.294 0.286 rg 0.347 0 Td (, )Tj 0.05 Tc 8.4881 0 0 8.1 117.52 374.65 Tm (Gur )Tj -0.035 Tc 8.1 0 0 8.1 135.78 374.65 Tm (I, )Tj 0.0009 Tc 1.128 0 Td (Bar)Tj 0.451 0.451 0.447 rg 0 Tc 1.416 0 Td (-)Tj 0.29 0.294 0.286 rg 0.016 Tc 0.364 0 Td (Yishay )Tj 0.353 0.353 0.349 rg -0.035 Tc 7.6834 0 0 8.1 187.16 374.65 Tm (E, )Tj 0.0301 Tc 8.1 0 0 8.1 197.68 374.65 Tm (Godfrey )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf -0.035 Tc 7.8213 0 0 8.1 230.26 374.65 Tm (S. )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 240.39 374.65 Tm (-)Tj 0.188 0.188 0.18 rg 1.132 0 Td (R)Tj 0.29 0.294 0.286 rg 0.0259 Tc 0.646 0 Td (efractory )Tj 0.0127 Tc -24.165 -1.068 Td (period )Tj 0.0007 Tc 3.188 0 Td (following )Tj 0.0089 Tc 4.447 0 Td (induced )Tj 0.0274 Tc 3.732 0 Td (asthma: )Tj 0.353 0.353 0.349 rg 0.0314 Tc 3.793 0 Td (contributions )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.9033 0 0 8.1 231.76 366 Tm (of )Tj 0.0011 Tc 8.1 0 0 8.1 242.31 366 Tm (exercise )Tj 0.0248 Tc 3.794 0 Td (and )Tj 0.012 Tc -26.428 -1.125 Td (isocapnic )Tj 0.0162 Tc 4.215 0 Td (hyperventilation. )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_2 1 Tf 0.0027 Tc 8.2 0 0 8.2 153.91 356.89 Tm (Thorax, )Tj EMC ET BT 0.188 0.188 0.18 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 184.04 356.89 Tm (1)Tj 0.29 0.294 0.286 rg -0.0022 Tc 0.32 0 Td (983, )Tj 0.353 0.353 0.349 rg -0.014 Tc 2.133 0 Td (38, )Tj 0.0083 Tc 1.535 0 Td (849)Tj 0.451 0.451 0.447 rg 0 Tc 1.488 0 Td (-)Tj 0.29 0.294 0.286 rg -0.0185 Tc 0.586 0 Td (853. )Tj 0.353 0.353 0.349 rg -0.035 Tc 7.6478 0 0 8.1 58.96 347.76 Tm (7. )Tj 0.29 0.294 0.286 rg 0.029 Tc 8.1 0 0 8.1 72.92 347.76 Tm (Deal )Tj 0.0138 Tc 2.311 0 Td (EC, )Tj 0.0343 Tc 1.837 0 Td (McFadden )Tj 0.0434 Tc 4.919 0 Td (ER, )Tj 0.188 0.188 0.18 rg 0 Tc 1.953 0 Td (I)Tj 0.29 0.294 0.286 rg 0.0144 Tc 0.362 0 Td (ngram )Tj 0.0414 Tc 3.019 0 Td (RH, )Tj 0.0253 Tc 2.015 0 Td (Jaege)Tj 0.188 0.188 0.18 rg 0 Tc 2.315 0 Td (r )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.144 0 0 8.1 229.39 347.76 Tm (JJ.)Tj 0.765 0.765 0.753 rg 0 Tc 8.1 0 0 8.1 240.87 347.76 Tm (-)Tj 0.29 0.294 0.286 rg 0.0164 Tc 0.954 0 Td (Hyperpnea )Tj 0.05 Tc 8.1466 0 0 8.1 58.48 338.65 Tm (and )Tj 0.0198 Tc 8.1 0 0 8.1 73.91 338.65 Tm (heat )Tj -0.0321 Tc 2.064 0 Td (flux: )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0203 Tc 8.1 0 0 8.1 107.4521 338.65 Tm (irutia)Tj 0.188 0.188 0.18 rg 0 Tc 2.193 0 Td (l )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0232 Tc 8.1 0 0 8.1 129.5975 338.65 Tm (reaction )Tj 0.353 0.353 0.349 rg 0.0139 Tc 3.662 0 Td (sequence )Tj 0.29 0.294 0.286 rg 0.0095 Tc 4.035 0 Td (in )Tj 0.353 0.353 0.349 rg 0.0085 Tc 1.064 0 Td (exercise-induced )Tj 0.29 0.294 0.286 rg 0.0409 Tc 7.172 0 Td (asthma)Tj 0.451 0.451 0.447 rg 0 Tc 3.07 0 Td (. )Tj 0.29 0.294 0.286 rg /T1_3 1 Tf 7.8001 0 0 7.8001 58.49 330 Tm (J )Tj /T1_2 1 Tf 0.036 Tc 8.2 0 0 8.2 68.29 330 Tm (Appl )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.035 Tc 8.0365 0 0 8.2 89.82 330 Tm (Plrysiol: )Tj EMC ET BT /T1_2 1 Tf 0.0102 Tc 8.2 0 0 8.2 121.5 330 Tm (Respirat )Tj 0.353 0.353 0.349 rg -0.0216 Tc 4.098 0 Td (Environ )Tj 0.0005 Tc 3.805 0 Td (Exercise )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_2 1 Tf -0.0136 Tc 8.2 0 0 8.2 220.8676 330 Tm (Physio/, )Tj EMC ET BT /T1_0 1 Tf -0.035 Tc 8.0056 0 0 8.1 253.16 330 Tm (1979, )Tj -0.0248 Tc 8.1 0 0 8.1 275.49 330 Tm (46, )Tj -0.0016 Tc -26.785 -1.125 Td (476)Tj 0.561 0.561 0.553 rg 0 Tc 1.533 0 Td (-)Tj 0.29 0.294 0.286 rg -0.0054 Tc 0.481 0 Td (483. )Tj 0 Tc -2.028 -1.067 Td (8)Tj 0.451 0.451 0.447 rg 0.53 0 Td (. )Tj 0.29 0.294 0.286 rg 0.0195 Tc 1.26 0 Td (Eschenbacher )Tj 0.05 Tc 8.1186 0 0 8.1 121.41 312.25 Tm (WL)Tj 0.451 0.451 0.447 rg 0 Tc 8.1 0 0 8.1 134.75 312.25 Tm (, )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0244 Tc 8.1 0 0 8.1 138.5732 312.25 Tm (Sheppard )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 172.7633 312.25 Tm (D)Tj 0.451 0.451 0.447 rg 0.814 0 Td (.)Tj 0.561 0.561 0.553 rg 0.484 0 Td (-)Tj 0.29 0.294 0.286 rg 0.05 Tc 8.4745 0 0 8.1 190.04 312.25 Tm (RHL )Tj -0.035 Tc 7.8068 0 0 8.1 209.7 312.25 Tm (is )Tj 0.015 Tc 8.1 0 0 8.1 216.95 312.25 Tm (not )Tj 0.043 Tc 1.599 0 Td (the )Tj 0.0252 Tc 1.47 0 Td (sole )Tj 0.353 0.353 0.349 rg 0.0109 Tc 1.896 0 Td (stimulus )Tj 0.29 0.294 0.286 rg 0.0296 Tc -24.531 -1.127 Td (for )Tj 0.353 0.353 0.349 rg 0.024 Tc 1.612 0 Td (bronchoconstriction )Tj 0.0089 Tc 8.82 0 Td (induced )Tj -0.035 Tc 8.0386 0 0 8.1 172.81 303.12 Tm (by )Tj 0.29 0.294 0.286 rg 0.012 Tc 8.1 0 0 8.1 183.77 303.12 Tm (isocapnic )Tj 0.0284 Tc 4.215 0 Td (hyperpnea )Tj 0.0021 Tc 4.741 0 Td (with )Tj 0.353 0.353 0.349 rg 0.0195 Tc 2.184 0 Td (dry )Tj 0 Tc -26.607 -1.126 Td (a)Tj 0.188 0.188 0.18 rg 0.535 0 Td (i)Tj 0.353 0.353 0.349 rg 0.244 0 Td (r)Tj 0.451 0.451 0.447 rg 0.395 0 Td (. )Tj 0.353 0.353 0.349 rg /T1_2 1 Tf 0.05 Tc 8.3646 0 0 8.2 72.61 294 Tm (Am )Tj 0.29 0.294 0.286 rg 0.0144 Tc 8.2 0 0 8.2 87.42 294 Tm (Rev )Tj -0.0059 Tc 1.873 0 Td (Respir )Tj 0.353 0.353 0.349 rg -0.0204 Tc 2.929 0 Td (Dis, )Tj /T1_0 1 Tf -0.0261 Tc 8.1 0 0 8.1 143.24 294 Tm (1985, )Tj ET BT /Suspect <>BDC 0.188 0.188 0.18 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 164.3567 294 Tm (1)Tj 0.353 0.353 0.349 rg 0.05 Tc 0.379 0 Td (31,894)Tj 0.647 0.647 0.635 rg 0 Tc 2.963 0 Td (-)Tj 0.353 0.353 0.349 rg -0.0219 Tc 0.652 0 Td (901. )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf -0.035 Tc 7.6511 0 0 8.1 58.47 284.89 Tm (9. )Tj 0.0293 Tc 8.1 0 0 8.1 72.4 284.89 Tm (Gelb )Tj 0 Tc 2.32 0 Td (A)Tj 0.188 0.188 0.18 rg 0.827 0 Td (F)Tj 0.353 0.353 0.349 rg 0.575 0 Td (. )Tj 0.29 0.294 0.286 rg 0.0292 Tc 0.546 0 Td (Tashkin )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 137.7184 284.89 Tm (D)Tj 0.188 0.188 0.18 rg 0.77 0 Td (P)Tj 0.29 0.294 0.286 rg 0.581 0 Td (, )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0123 Tc 8.1 0 0 8.1 153.0679 284.89 Tm (Eplinstein )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.2597 0 0 8.1 189.55 284.89 Tm (JD, )Tj 8.3498 0 0 8.1 204.4 284.89 Tm (Gong )Tj 0 Tc 8.1 0 0 8.1 226.52 284.89 Tm (H )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 8.7976 0 0 8.1 234.67 284.89 Tm (Jr)Tj 0.451 0.451 0.447 rg 0 Tc 8.1 0 0 8.1 241.31 284.89 Tm (, )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0174 Tc 8.1 0 0 8.1 245.7326 284.89 Tm (Zamel )Tj 0.353 0.353 0.349 rg -0.0239 Tc 3.031 0 Td (N. )Tj 0.561 0.561 0.553 rg 0 Tc 1.288 0 Td (-)Tj 0.353 0.353 0.349 rg 0.0017 Tc 3.799 58.074 Td (Exercise )Tj 0.29 0.294 0.286 rg 0.0089 Tc 4.026 0 Td (induced )Tj 0.0271 Tc 3.921 0 Td (bronchodilation )Tj -0.035 Tc 7.9356 0 0 8.1 435.3 755.29 Tm (in )Tj 0.353 0.353 0.349 rg 0.0319 Tc 8.1 0 0 8.1 446.8 755.29 Tm (asthma. )Tj /T1_2 1 Tf 0.0043 Tc 8.2 0 0 8.2 478.88 755.29 Tm (Chest)Tj 0.451 0.451 0.447 rg 0 Tc 2.306 0 Td (, )Tj 0.29 0.294 0.286 rg /T1_0 1 Tf -0.0305 Tc 8.1 0 0 8.1 506.12 755.29 Tm (1985)Tj 0.451 0.451 0.447 rg 0 Tc 1.856 0 Td (, )Tj 0.29 0.294 0.286 rg -0.0149 Tc 0.888 0 Td (87, )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf -0.035 Tc 7.5202 0 0 8.1 311.74 746.65 Tm (19)Tj 0.451 0.451 0.447 rg 0.05 Tc 10.0653 0 0 8.1 318.6 746.65 Tm (6-)Tj 0.353 0.353 0.349 rg -0.0239 Tc 8.1 0 0 8.1 327.31 746.65 Tm (201. )Tj EMC /Suspect <>BDC -0.035 Tc 7.3607 0 0 8.1 311.75 737.53 Tm (10. )Tj EMC ET BT /T1_0 1 Tf 0.0202 Tc 8.1 0 0 8.1 329.2 737.53 Tm (Godfrey )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf -0.035 Tc 7.8213 0 0 8.1 362.74 737.53 Tm (S. )Tj EMC ET BT 0.451 0.451 0.447 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 373.83 737.53 Tm (-)Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_2 1 Tf -0.035 Tc 7.2371 0 0 8.2 384.07 737.53 Tm (In: )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0017 Tc 8.1 0 0 8.1 397.88 737.53 Tm (Exercise )Tj 0.29 0.294 0.286 rg 0.0109 Tc 4.091 0 Td (testing )Tj 0.0095 Tc 3.372 0 Td (in )Tj 0.014 Tc 1.421 0 Td (children. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0262 Tc 8.1 0 0 8.1 504.8081 737.53 Tm (Saunders, )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0445 Tc 8.1 0 0 8.1 310.9994 728.8873 Tm (London, )Tj 0.29 0.294 0.286 rg -0.0261 Tc 4 0 Td (1974. )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0.05 Tc 8.1495 0 0 8.1 311.94 719.76 Tm (II. )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 8.1256 0 0 8.1 329.24 719.76 Tm (Hahn )Tj -0.018 Tc 8.1 0 0 8.1 350.87 719.76 Tm (A, )Tj 0.0297 Tc 1.304 0 Td (Anderson )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0236 Tc 8.1 0 0 8.1 397.2911 719.76 Tm (SD, )Tj EMC ET BT /T1_0 1 Tf 0.0423 Tc 8.1 0 0 8.1 413.24 719.76 Tm (Morton )Tj 0.0432 Tc 3.619 0 Td (AR. )Tj 0.0009 Tc 2.13 0 Td (Black )Tj 0.0314 Tc 2.667 0 Td (JL, )Tj 0.0244 Tc 1.72 0 Td (Fitch )Tj 0.05 Tc 8.6873 0 0 8.1 515.96 719.76 Tm (KD)Tj 0.451 0.451 0.447 rg 0 Tc 8.1 0 0 8.1 529.27 719.76 Tm [(. )-43(-)]TJ 0.29 0.294 0.286 rg -26.943 -1.067 Td (A )Tj 0.0241 Tc 1.067 0 Td (re-interpretation )Tj 0.353 0.353 0.349 rg 0.05 Tc 9.4598 0 0 8.1 378.15 711.12 Tm (of )Tj 0.29 0.294 0.286 rg 0.0134 Tc 8.1 0 0 8.1 388.3 711.12 Tm (the )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf -0.0001 Tc 8.1 0 0 8.1 400.7092 711.12 Tm (effect )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.05 Tc 8.9033 0 0 8.1 421.84 711.12 Tm (of )Tj 0.353 0.353 0.349 rg 0.033 Tc 8.1 0 0 8.1 431.5 711.12 Tm (temperature )Tj 0.29 0.294 0.286 rg 0.0248 Tc 5.444 0 Td (and )Tj 0.0244 Tc 1.905 0 Td (water )Tj 0.0368 Tc 2.658 0 Td (content )Tj 0.353 0.353 0.349 rg 0.05 Tc 8.9033 0 0 8.1 310.96 702 Tm (of )Tj 0.0134 Tc 8.1 0 0 8.1 320.62 702 Tm (the )Tj 0.29 0.294 0.286 rg 0.0165 Tc 1.535 0 Td (inspired )Tj 0.042 Tc 3.673 0 Td (air )Tj 0.0095 Tc 1.423 0 Td (in )Tj 0.353 0.353 0.349 rg 0.0045 Tc 1.064 0 Td (exercise-induced )Tj 0.29 0.294 0.286 rg 0.0409 Tc 7.172 0 Td (asthma)Tj 0.188 0.188 0.18 rg 0 Tc 3.13 0 Td (. )Tj 0.353 0.353 0.349 rg /T1_2 1 Tf 0.05 Tc 8.3646 0 0 8.2 471.01 702 Tm (Am )Tj 0.29 0.294 0.286 rg 0.0144 Tc 8.2 0 0 8.2 485.82 702 Tm (Rev )Tj 0.0058 Tc 1.815 0 Td (Respir )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.0204 Tc 8.2 0 0 8.2 525.2046 702 Tm (Dis, )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf -0.0261 Tc 8.1 0 0 8.1 311.72 693.36 Tm (1984, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 7.9309 0 0 8.1 332.37 693.36 Tm (130, )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0179 Tc 8.1 0 0 8.1 348.37 693.36 Tm (575-579. )Tj 0.353 0.353 0.349 rg -0.035 Tc 7.3607 0 0 8.1 311.75 684.24 Tm (12. )Tj 0.29 0.294 0.286 rg 0.0294 Tc 8.1 0 0 8.1 328.76 684.24 Tm (Kilham )Tj 0 Tc 3.496 0 Td (H)Tj 0.451 0.451 0.447 rg 0.814 0 Td (. )Tj 0.29 0.294 0.286 rg 0.018 Tc 0.486 0 Td (Tooley )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0025 Tc 8.1 0 0 8.1 394.0379 684.24 Tm (M, )Tj EMC ET BT /T1_0 1 Tf 0.0096 Tc 8.1 0 0 8.1 405.9287 684.24 Tm (Silverman )Tj -0.0025 Tc 4.517 0 Td (M.)Tj 0.561 0.561 0.553 rg 0 Tc 1.475 0 Td (-)Tj 0.29 0.294 0.286 rg 0.0389 Tc 0.895 0 Td (Running)Tj 0.451 0.451 0.447 rg 0 Tc 3.722 0 Td (, )Tj 0.29 0.294 0.286 rg -0.0209 Tc 0.548 0 Td (walk.ing )Tj 0.0248 Tc 3.606 0 Td (and )Tj 0.353 0.353 0.349 rg 0.0142 Tc -26.48 -1.126 Td (hyperventilation )Tj 0.0181 Tc 7.339 0 Td (causing )Tj 0.029 Tc 3.674 0 Td (asthma )Tj 0.0095 Tc 3.557 0 Td (in )Tj 0.0214 Tc 1.302 0 Td (children. )Tj 0.29 0.294 0.286 rg /T1_2 1 Tf 0.0027 Tc 8.2 0 0 8.2 474.55 675.12 Tm (Thorax, )Tj /T1_0 1 Tf -0.0261 Tc 8.1 0 0 8.1 506.6 675.12 Tm (1979, )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf -0.014 Tc 8.1 0 0 8.1 528.389 675.12 Tm (34, )Tj EMC ET BT /T1_0 1 Tf 0.0179 Tc 8.1 0 0 8.1 310.9283 666.4773 Tm (582-586. )Tj 0.29 0.294 0.286 rg -0.035 Tc 7.3607 0 0 8.1 311.75 657.36 Tm (13. )Tj 0.0343 Tc 8.1 0 0 8.1 329.24 657.36 Tm (McFadden )Tj 0.188 0.188 0.18 rg 0 Tc 4.859 0 Td (E)Tj 0.29 0.294 0.286 rg -0.0248 Tc 0.652 0 Td (R.)Tj 0.561 0.561 0.553 rg 0 Tc 1.179 0 Td (-)Tj 0.29 0.294 0.286 rg -0.031 Tc 0.899 0 Td (An )Tj 0.0075 Tc 1.532 0 Td (analysis )Tj 0.353 0.353 0.349 rg 0.05 Tc 9.4598 0 0 8.1 431.43 657.36 Tm (of )Tj 0.0011 Tc 8.1 0 0 8.1 440.55 657.36 Tm (exercise )Tj 0.0087 Tc 3.557 0 Td (as )Tj 0.29 0.294 0.286 rg 0 Tc 1.126 0 Td (a )Tj 0.353 0.353 0.349 rg 0.0278 Tc 0.707 0 Td (stimulus )Tj 0.29 0.294 0.286 rg 0 Tc 3.914 0 Td (for )Tj 0.353 0.353 0.349 rg 0.0134 Tc 1.49 0 Td (the )Tj 0.29 0.294 0.286 rg 0.0269 Tc -26.781 -1.065 Td (production )Tj 0.05 Tc 9.4598 0 0 8.1 350.79 648.73 Tm (of )Tj 0.353 0.353 0.349 rg 0.0156 Tc 8.1 0 0 8.1 360.88 648.73 Tm (airway )Tj 0.0265 Tc 3.141 0 Td (obstruction)Tj 0.451 0.451 0.447 rg 0 Tc 4.848 0 Td (. )Tj 0.353 0.353 0.349 rg /T1_2 1 Tf 0.0089 Tc 8.2 0 0 8.2 430.16 648.73 Tm (Lung, )Tj 0.29 0.294 0.286 rg /T1_0 1 Tf -0.035 Tc 7.6333 0 0 8.1 452.86 648.73 Tm (1981)Tj 0.451 0.451 0.447 rg 0 Tc 8.1 0 0 8.1 468.35 648.73 Tm (, )Tj 0.353 0.353 0.349 rg -0.035 Tc 7.7728 0 0 8.1 473.97 648.73 Tm (159)Tj 0.451 0.451 0.447 rg 0 Tc 8.1 0 0 8.1 485.15 648.73 Tm (, )Tj 0.353 0.353 0.349 rg 0.05 Tc 8.1208 0 0 8.1 489.99 648.73 Tm (3-11. )Tj 0.29 0.294 0.286 rg -0.035 Tc 7.7937 0 0 8.1 311.25 639.61 Tm (14. )Tj 0.0343 Tc 8.1 0 0 8.1 328.76 639.61 Tm (McFadden )Tj 0.0434 Tc 5.037 0 Td (ER, )Tj 0.353 0.353 0.349 rg 0.0292 Tc 2.015 0 Td (Lenner )Tj 0.0448 Tc 3.378 0 Td (KAN, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0279 Tc 8.1 0 0 8.1 437.1299 639.61 Tm (Strohl )Tj EMC /Suspect <>BDC 0.29 0.294 0.286 rg 0.05 Tc 8.6888 0 0 8.1 461.72 639.61 Tm (KP)Tj 0.451 0.451 0.447 rg 16.2603 0 0 8.1 472.94 639.61 Tm (.-)Tj EMC /Suspect <>BDC 0.29 0.294 0.286 rg 0.0237 Tc 8.1 0 0 8.1 486.2 639.61 Tm (Post )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0194 Tc 8.1 0 0 8.1 503.9066 639.61 Tm (exertional )Tj 0.0156 Tc -23.88 -1.127 Td (airway )Tj 0.29 0.294 0.286 rg 0.022 Tc 3.386 0 Td (rewarming )Tj 0.05 Tc 8.1466 0 0 8.1 378.16 630.48 Tm (and )Tj 0.0182 Tc 8.1 0 0 8.1 395.02 630.48 Tm (thermally)Tj 0.451 0.451 0.447 rg 0 Tc 3.962 0 Td (-)Tj 0.353 0.353 0.349 rg 0.0187 Tc 0.358 0 Td (induced )Tj 0.29 0.294 0.286 rg 0.0409 Tc 3.791 0 Td (asthma)Tj 0.451 0.451 0.447 rg 0 Tc 3.13 0 Td (. )Tj 0.29 0.294 0.286 rg 0.0046 Tc 0.796 0 Td (New )Tj 0.353 0.353 0.349 rg 0.0068 Tc 2.475 0 Td (insights )Tj 0.0207 Tc -24.889 -1.065 Td (into )Tj 0.29 0.294 0.286 rg 0.02 Tc 2.202 0 Td (pathophysiology )Tj 0.05 Tc 8.1466 0 0 8.1 389.68 621.85 Tm (and )Tj -0.0006 Tc 8.1 0 0 8.1 407.05 621.85 Tm (possibly )Tj 0.019 Tc 3.911 0 Td (pathogenesis. )Tj 0.353 0.353 0.349 rg /T1_3 1 Tf 0 Tc 7.7 0 0 7.7 488.57 621.85 Tm (J )Tj /T1_2 1 Tf -0.0239 Tc 8.2 0 0 8.2 497.6 621.85 Tm (Clin )Tj 0.29 0.294 0.286 rg -0.0033 Tc 2.254 0 Td (Invest)Tj 0.451 0.451 0.447 rg 0 Tc 2.452 0 Td (, )Tj 0.29 0.294 0.286 rg /T1_0 1 Tf -0.0305 Tc 8.1 0 0 8.1 311.24 612.73 Tm (1986)Tj 0.451 0.451 0.447 rg 0 Tc 1.856 0 Td (, )Tj 0.29 0.294 0.286 rg -0.0201 Tc 0.598 0 Td (78, )Tj 0.353 0.353 0.349 rg 0.0192 Tc 1.695 0 Td (18-25. )Tj 0.29 0.294 0.286 rg -0.0288 Tc -4.121 -1.067 Td (IS. )Tj 0.0428 Tc 2.077 0 Td (McFadden )Tj 0.05 Tc 8.3316 0 0 8.1 367.63 604.09 Tm (ER. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.02 Tc 8.1 0 0 8.1 383.48 604.09 Tm (Pichurko )Tj EMC ET BT /T1_0 1 Tf -0.0028 Tc 8.1 0 0 8.1 416.6009 604.09 Tm (BM.)Tj 0.561 0.561 0.553 rg 0 Tc 2.068 0 Td (-)Tj 0.188 0.188 0.18 rg 0.833 0 Td (I)Tj 0.29 0.294 0.286 rg 0.0318 Tc 0.362 0 Td (ntra-airway )Tj 0.353 0.353 0.349 rg 0.0254 Tc 5.154 0 Td (thermal )Tj 0.29 0.294 0.286 rg 0.0055 Tc 3.5 0 Td (profiles )Tj 0.353 0.353 0.349 rg 0.0368 Tc -25.018 -1.126 Td (during )Tj 0.0011 Tc 3.021 0 Td (exercise )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.1466 0 0 8.1 363.76 594.97 Tm (and )Tj 0.0181 Tc 8.1 0 0 8.1 379.19 594.97 Tm (hyperventilation )Tj 0.0095 Tc 7.163 0 Td (in )Tj 0.0273 Tc 1.133 0 Td (normal )Tj 0.0015 Tc 3.377 0 Td (man)Tj 0.188 0.188 0.18 rg 0 Tc 1.819 0 Td (. )Tj 0.29 0.294 0.286 rg /T1_3 1 Tf 7.7 0 0 7.7 492.89 594.97 Tm (J )Tj 0.353 0.353 0.349 rg /T1_2 1 Tf -0.0239 Tc 8.2 0 0 8.2 499.52 594.97 Tm (Clin )Tj 0.29 0.294 0.286 rg -0.0152 Tc 2.078 0 Td (Invest, )Tj /T1_0 1 Tf -0.035 Tc 7.8965 0 0 8.1 311.25 586.33 Tm (1985)Tj 0.451 0.451 0.447 rg 0 Tc 8.1 0 0 8.1 326.27 586.33 Tm (, )Tj 0.29 0.294 0.286 rg -0.0201 Tc 0.598 0 Td (76, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0057 Tc 8.1 0 0 8.1 344.8433 586.33 Tm (1007-1010. )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf -0.035 Tc 7.7937 0 0 8.1 311.25 577.21 Tm (16. )Tj 0.29 0.294 0.286 rg 0.0157 Tc 8.1 0 0 8.1 328.36 577.21 Tm (Noviski )Tj 0.0354 Tc 3.911 0 Td (N, )Tj 0.0174 Tc 1.59 0 Td (Bar-Yishay )Tj 0.353 0.353 0.349 rg 0 Tc 5.333 0 Td (E)Tj 0.451 0.451 0.447 rg 0.641 0 Td (, )Tj 0.353 0.353 0.349 rg 0.05 Tc 8.4881 0 0 8.1 428.08 577.21 Tm (Gur )Tj 0.29 0.294 0.286 rg -0.035 Tc 8.1 0 0 8.1 446.82 577.21 Tm (I, )Tj 0.0301 Tc 1.183 0 Td (Godfrey )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 7.8213 0 0 8.1 489.46 577.21 Tm (S. )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 500.55 577.21 Tm (-)Tj 0.29 0.294 0.286 rg 0.0017 Tc 1.191 0 Td (Exercise )Tj 0.353 0.353 0.349 rg 0.0091 Tc -24.656 -1.126 Td (intensity )Tj 0.29 0.294 0.286 rg 0.0118 Tc 3.791 0 Td (determines, )Tj 0.0248 Tc 5.096 0 Td (and )Tj 0.0178 Tc 1.778 0 Td (climatic )Tj 0.353 0.353 0.349 rg 0.0269 Tc 3.556 0 Td (conditions )Tj 0.29 0.294 0.286 rg 0.0161 Tc 4.689 0 Td (modify )Tj 0.0134 Tc 3.319 0 Td (the )Tj 0.353 0.353 0.349 rg 0.0175 Tc 1.47 0 Td (severity )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.9033 0 0 8.1 530.8 568.09 Tm (of )Tj 0.353 0.353 0.349 rg 0.0011 Tc 8.1 0 0 8.1 309.99 559.44 Tm (exercise)Tj 0.451 0.451 0.447 rg 0 Tc 3.259 0 Td (-)Tj 0.29 0.294 0.286 rg 0.0089 Tc 0.358 0 Td (induced )Tj 0.353 0.353 0.349 rg 0.0319 Tc 3.614 0 Td (asthma. )Tj /T1_2 1 Tf 0.05 Tc 8.7132 0 0 8.2 398.05 559.44 Tm (Am )Tj 0 Tc 8.2 0 0 8.2 412.86 559.44 Tm (R)Tj 0.451 0.451 0.447 rg 0.628 0 Td (e)Tj 0.353 0.353 0.349 rg 0.529 0 Td (v )Tj 0.29 0.294 0.286 rg -0.0059 Tc 0.774 0 Td (Respir )Tj 0.353 0.353 0.349 rg -0.0204 Tc 2.871 0 Td (Dis, )Tj 0.29 0.294 0.286 rg /T1_0 1 Tf -0.0261 Tc 8.1 0 0 8.1 469.16 559.44 Tm (1987. )Tj 0.05 Tc 8.2921 0 0 8.1 489.06 559.44 Tm (In )Tj 0.0032 Tc 8.1 0 0 8.1 499.69 559.44 Tm (press. )Tj 0.353 0.353 0.349 rg -0.035 Tc 7.3607 0 0 8.1 311.27 550.33 Tm (17. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0291 Tc 8.1 0 0 8.1 328.24 550.33 Tm (O'Byrne )Tj EMC /Suspect <>BDC 0.29 0.294 0.286 rg 0.0491 Tc 4.035 0 Td (PM, )Tj EMC ET BT /T1_0 1 Tf 0.0394 Tc 8.1 0 0 8.1 379.1647 550.33 Tm (Jones )Tj 0.353 0.353 0.349 rg 0.05 Tc 8.7787 0 0 8.1 402.15 550.33 Tm (GL)Tj 0.561 0.561 0.553 rg 0 Tc 8.1 0 0 8.1 414.07 550.33 Tm [(. )-221(-)]TJ 0.353 0.353 0.349 rg 0.05 Tc 8.2125 0 0 8.1 428.09 550.33 Tm (The )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0001 Tc 8.1 0 0 8.1 445.35 550.33 Tm (effect )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.9033 0 0 8.1 467.43 550.33 Tm (of )Tj 0.29 0.294 0.286 rg 0.0298 Tc 8.1 0 0 8.1 478.49 550.33 Tm (indomethacin )Tj 0.0278 Tc 6.28 0 Td (on )Tj 0.353 0.353 0.349 rg 0.0011 Tc -27.083 -1.068 Td (exercise )Tj 0.0187 Tc 4.091 0 Td (induced )Tj 0.0494 Tc 4.158 0 Td (bro)Tj 0.188 0.188 0.18 rg 0 Tc 1.479 0 Td (n)Tj 0.353 0.353 0.349 rg 0.0232 Tc 0.465 0 Td (choconsriction )Tj 0.05 Tc 8.1466 0 0 8.1 449.2 541.68 Tm (and )Tj 0.0149 Tc 8.1 0 0 8.1 469.43 541.68 Tm (refractoriness )Tj 0.0344 Tc 6.51 0 Td (after )Tj 0.0011 Tc -26.194 -1.126 Td (exercise)Tj 0.188 0.188 0.18 rg 0 Tc 3.309 0 Td (. )Tj 0.353 0.353 0.349 rg /T1_2 1 Tf 0.05 Tc 8.3646 0 0 8.2 341.41 532.56 Tm (Am )Tj 0.29 0.294 0.286 rg 0.0144 Tc 8.2 0 0 8.2 356.22 532.56 Tm (Rev )Tj 0.353 0.353 0.349 rg 0.0058 Tc 1.815 0 Td (Respir )Tj -0.0075 Tc 3.046 0 Td (Di)Tj 0.451 0.451 0.447 rg 0 Tc 0.872 0 Td (s)Tj 0.353 0.353 0.349 rg 0.468 0 Td (, )Tj /T1_0 1 Tf -0.035 Tc 8.0056 0 0 8.1 412.52 532.56 Tm (1986, )Tj -0.0328 Tc 8.1 0 0 8.1 432.68 532.56 Tm (134)Tj 0.451 0.451 0.447 rg 0 Tc 1.441 0 Td (, )Tj 0.353 0.353 0.349 rg -0.0273 Tc 0.596 0 Td (69)Tj 0.561 0.561 0.553 rg 0 Tc 1.009 0 Td (-)Tj 0.353 0.353 0.349 rg -0.0201 Tc 0.533 0 Td (72. )Tj -0.035 Tc 7.7937 0 0 8.1 310.77 523.44 Tm (18. )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0292 Tc 8.1 0 0 8.1 328.17 523.44 Tm (Stearns )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.3651 0 0 8.1 358.52 523.44 Tm (DR, )Tj 0.0343 Tc 8.1 0 0 8.1 379.16 523.44 Tm (McFadden )Tj 0.353 0.353 0.349 rg 0.05 Tc 8.3316 0 0 8.1 421.39 523.44 Tm (ER, )Tj 0.29 0.294 0.286 rg -0.0032 Tc 8.1 0 0 8.1 440.6 523.44 Tm (Breslin )Tj 0 Tc 3.557 0 Td (F)Tj 0.188 0.188 0.18 rg 0.591 0 Td (J)Tj 0.29 0.294 0.286 rg 0.517 0 Td (. )Tj 0.042 Tc 0.902 0 Td (Ingram )Tj 0 Tc 3.736 0 Td (J)Tj 0.188 0.188 0.18 rg 0.533 0 Td (R)Tj 0.29 0.294 0.286 rg 0.695 0 Td (. )Tj 0.353 0.353 0.349 rg 0.958 0 Td (-)Tj 0.29 0.294 0.286 rg 0.0191 Tc -27.549 -1.067 Td (Reanalys)Tj 0.451 0.451 0.447 rg 0 Tc 3.848 0 Td (i)Tj 0.353 0.353 0.349 rg 0.232 0 Td (s )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.9033 0 0 8.1 349.84 514.8 Tm (of )Tj 0.353 0.353 0.349 rg 0.0134 Tc 8.1 0 0 8.1 360.94 514.8 Tm (the )Tj 0.188 0.188 0.18 rg 0 Tc 1.66 0 Td (r)Tj 0.353 0.353 0.349 rg 0.0259 Tc 0.346 0 Td (efractory )Tj 0.0245 Tc 4.279 0 Td (period )Tj 0.0095 Tc 3.072 0 Td (in )Tj 0.0194 Tc 1.242 0 Td (exertional )Tj 0.0319 Tc 4.623 0 Td (asthma. )Tj 0.29 0.294 0.286 rg /T1_3 1 Tf 0 Tc 7.8001 0 0 7.8001 514.49 514.8 Tm (J )Tj /T1_2 1 Tf 0.0165 Tc 8.2 0 0 8.2 522.37 514.8 Tm (Appl )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.0087 Tc 8.2 0 0 8.2 310.1376 505.6898 Tm (Physiol: )Tj EMC ET BT /T1_2 1 Tf -0.0065 Tc 8.2 0 0 8.2 340.8548 505.6898 Tm (Respirat )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.0216 Tc 8.2 0 0 8.2 371.0964 505.6898 Tm (Environ )Tj EMC ET BT /T1_2 1 Tf 0.0308 Tc 8.2 0 0 8.2 399.8948 505.6898 Tm (Exer)Tj 0.451 0.451 0.447 rg 0 Tc 1.917 0 Td (c)Tj 0.353 0.353 0.349 rg -0.0192 Tc 0.463 0 Td (ise )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_2 1 Tf -0.0053 Tc 8.2 0 0 8.2 431.0876 505.6898 Tm (Physiol, )Tj EMC ET BT 0.188 0.188 0.18 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 461.48 505.69 Tm (1)Tj 0.29 0.294 0.286 rg -0.0022 Tc 0.32 0 Td (981, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 6.7442 0 0 8.1 481.32 505.69 Tm (SO, )Tj EMC /Suspect <>BDC 0.0184 Tc 8.1 0 0 8.1 494.25 505.69 Tm (S03-508. )Tj EMC ET BT /T1_0 1 Tf -0.035 Tc 7.7937 0 0 8.1 310.77 497.05 Tm (19. )Tj 0.353 0.353 0.349 rg 0.0022 Tc 8.1 0 0 8.1 328.29 497.05 Tm (Zcilinski )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf 0.021 Tc 8.1 0 0 8.1 361.8807 497.05 Tm (J, )Tj EMC ET BT /T1_0 1 Tf 0.0275 Tc 8.1 0 0 8.1 371.9247 497.05 Tm (Chodowska )Tj 0 Tc 5.516 0 Td (E)Tj 0.451 0.451 0.447 rg 0.7 0 Td (, )Tj 0.29 0.294 0.286 rg 0.0165 Tc 0.841 0 Td (Radomyski )Tj -0.018 Tc 5.337 0 Td (A, )Tj 0.011 Tc 1.541 0 Td (Araskiewicz )Tj 0.353 0.353 0.349 rg 0.0411 Tc 5.627 0 Td (Z, )Tj 0.0146 Tc -27.201 -1.126 Td (Kozlowski )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf -0.035 Tc 7.8213 0 0 8.1 350.74 487.93 Tm (S. )Tj EMC /Suspect <>BDC 0.451 0.451 0.447 rg 0 Tc 8.1 0 0 8.1 361.35 487.93 Tm (-)Tj EMC /Suspect <>BDC 0.188 0.188 0.18 rg 1.132 0 Td (P)Tj 0.353 0.353 0.349 rg 0.0142 Tc 0.589 0 Td (lasma )Tj EMC ET BT /T1_0 1 Tf 0.0204 Tc 8.1 0 0 8.1 398.7963 487.93 Tm (catecholamines )Tj 0.0368 Tc 6.933 0 Td (during )Tj 0.0085 Tc 3.317 0 Td (exercise-induced )Tj 0.29 0.294 0.286 rg 0.024 Tc -21.143 -1.126 Td (bronchoconstriction )Tj 0.353 0.353 0.349 rg -0.035 Tc 7.9356 0 0 8.1 385.38 478.81 Tm (in )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0115 Tc 8.1 0 0 8.1 398.41 478.81 Tm (broncrual )Tj EMC ET BT /T1_0 1 Tf 0.0319 Tc 8.1 0 0 8.1 436.723 478.81 Tm (asthma. )Tj 0.353 0.353 0.349 rg /T1_2 1 Tf 0.0027 Tc 8.2 0 0 8.2 470.23 478.81 Tm (Thorax, )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf -0.0305 Tc 8.1 0 0 8.1 504.2 478.81 Tm (1980)Tj 0.451 0.451 0.447 rg 0 Tc 1.856 0 Td (, )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf -0.014 Tc 8.1 0 0 8.1 527.9168 478.81 Tm (35, )Tj 0.0265 Tc -26.91 -1.068 Td (823-827. )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0392 Tc 8.1 0 0 8.1 310.529 455.2795 Tm (RESUME: )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 351.7904 455.2795 Tm (I)Tj 0.188 0.188 0.18 rg 0.358 0 Td (J )Tj 0.29 0.294 0.286 rg 0.706 0 Td (a )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.021 Tc 8.1 0 0 8.1 368.0795 455.2795 Tm (ete )Tj EMC /Suspect <>BDC 0.0097 Tc 1.657 0 Td (suggere )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0.05 Tc 8.142 0 0 8.1 410.8 455.28 Tm (que )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf -0.035 Tc 7.9307 0 0 8.1 427.15 455.28 Tm (Ia )Tj EMC ET BT /T1_0 1 Tf 0.0218 Tc 8.1 0 0 8.1 437.29 455.28 Tm (perle )Tj 0.353 0.353 0.349 rg 0.05 Tc 8.2927 0 0 8.1 457.84 455.28 Tm (de )Tj 0.29 0.294 0.286 rg 0.037 Tc 8.1 0 0 8.1 469.36 455.28 Tm (chaleur )Tj 0.0229 Tc 3.623 0 Td (respiratoire )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0329 Tc 8.1 0 0 8.1 309.9844 446.6535 Tm (\(PCR\) )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.05 Tc 8.3916 0 0 8.1 334 446.65 Tm (ou )Tj -0.035 Tc 7.7065 0 0 8.1 345.13 446.65 Tm (perLe )Tj 0.0339 Tc 8.1 0 0 8.1 363.76 446.65 Tm (d'eau )Tj 0.0229 Tc 2.557 0 Td (respiratoire )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0469 Tc 8.1 0 0 8.1 425.1904 446.65 Tm (\(PER\) )Tj EMC ET BT /T1_0 1 Tf 0.0457 Tc 8.1 0 0 8.1 448.6885 446.65 Tm (sont )Tj 0.29 0.294 0.286 rg 0.02 Tc 2.019 0 Td (des )Tj 0.0198 Tc 1.658 0 Td (facteurs )Tj 0.0024 Tc 3.627 0 Td (possibles )Tj 0.353 0.353 0.349 rg 0.0141 Tc -24.426 -1.126 Td (de )Tj 0.29 0.294 0.286 rg 0.0152 Tc 1.541 0 Td (declenchement )Tj 0.05 Tc 8.2927 0 0 8.1 377.68 437.53 Tm (de )Tj 0.0401 Tc 8.1 0 0 8.1 390.45 437.53 Tm (!'asthma )Tj 0.0291 Tc 4.242 0 Td (provoquc )Tj 0.05 Tc 8.4273 0 0 8.1 462.73 437.53 Tm (par )Tj 0.353 0.353 0.349 rg 0.0029 Tc 8.1 0 0 8.1 478.97 437.53 Tm (l'exercice )Tj 0.0109 Tc 4.442 0 Td (et )Tj 0.29 0.294 0.286 rg 0.048 Tc 1.435 0 Td (par )Tj 0 Tc -26.76 -1.067 Td (!)Tj 0.451 0.451 0.447 rg 0.259 0 Td (')Tj 0.29 0.294 0.286 rg 0.0181 Tc 0.306 0 Td (hyperventilation )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 8.163 0 0 8.1 371.9 428.89 Tm (\(APE )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 8.3173 0 0 8.1 393.03 428.89 Tm (et )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 401.75 428.89 Tm (A)Tj 0.188 0.188 0.18 rg 0.767 0 Td (P)Tj 0.29 0.294 0.286 rg 0.0228 Tc 0.593 0 Td (H\))Tj 0.451 0.451 0.447 rg 0 Tc 1.11 0 Td (. )Tj EMC /Suspect <>BDC 0.29 0.294 0.286 rg -0.035 Tc 7.0097 0 0 8.1 426.19 428.89 Tm (II )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 432.88 428.89 Tm (a )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf 0.021 Tc 8.1 0 0 8.1 439.1089 428.89 Tm (ete )Tj EMC /Suspect <>BDC 0.353 0.353 0.349 rg 0.0379 Tc 1.483 0 Td (demontre )Tj EMC /Suspect <>BDC 0.29 0.294 0.286 rg 0.0233 Tc 4.275 0 Td (recemment )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0.05 Tc 8.142 0 0 8.1 525.04 428.89 Tm (que )Tj 0.29 0.294 0.286 rg 0.0205 Tc 8.1 0 0 8.1 310.01 419.76 Tm (l'intensite )Tj 0.05 Tc 8.2927 0 0 8.1 345.52 419.76 Tm (de )Tj 0.353 0.353 0.349 rg 0.0095 Tc 8.1 0 0 8.1 356.57 419.76 Tm (l'exercice )Tj 0.29 0.294 0.286 rg 0.0202 Tc 4.206 0 Td (ainsi )Tj 0.353 0.353 0.349 rg 0.0243 Tc 2.37 0 Td (que )Tj 0.29 0.294 0.286 rg -0.0135 Tc 1.898 0 Td (les )Tj 0.0113 Tc 1.479 0 Td (facteurs )Tj 0.0217 Tc 3.675 0 Td (climatiques )Tj 0.353 0.353 0.349 rg 0.05 Tc 8.3094 0 0 8.1 508.68 419.76 Tm (sont )Tj 0.29 0.294 0.286 rg 0.02 Tc 8.1 0 0 8.1 526.48 419.76 Tm (des )Tj 0.353 0.353 0.349 rg 0.0328 Tc -26.785 -1.125 Td (determinants )Tj 0.29 0.294 0.286 rg 0.034 Tc 6.164 0 Td (importaots )Tj 0.05 Tc 8.2927 0 0 8.1 401.68 410.65 Tm (de )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf -0.035 Tc 7.2698 0 0 8.1 415.15 410.65 Tm (Ia )Tj EMC ET BT /T1_0 1 Tf 0.0144 Tc 8.1 0 0 8.1 426.17 410.65 Tm (gravitc )Tj 0.29 0.294 0.286 rg 0.0141 Tc 3.495 0 Td (de )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0284 Tc 8.1 0 0 8.1 467.7311 410.65 Tm (!'APE. )Tj EMC /Suspect <>BDC 0.29 0.294 0.286 rg 0.05 Tc 8.526 0 0 8.1 495.32 410.65 Tm (Hcit )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0233 Tc 8.1 0 0 8.1 516.19 410.65 Tm (jeunes )Tj 0.29 0.294 0.286 rg 0.0184 Tc -25.448 -1.126 Td (malades )Tj 0.353 0.353 0.349 rg 0.0279 Tc 3.667 0 Td (asthmatiques )Tj 0.05 Tc 8.138 0 0 8.1 386.8 401.53 Tm (ont )Tj 0.29 0.294 0.286 rg 0.019 Tc 8.1 0 0 8.1 400.24 401.53 Tm (chacun )Tj 0.0046 Tc 3.258 0 Td (fait )Tj 0.02 Tc 1.66 0 Td (des )Tj 0.353 0.353 0.349 rg -0.0025 Tc 1.599 0 Td (exercices )Tj 0.05 Tc 8.3173 0 0 8.1 485.19 401.53 Tm (et )Tj 0.29 0.294 0.286 rg 0.0205 Tc 8.1 0 0 8.1 493.36 401.53 Tm (accompli )Tj 0.353 0.353 0.349 rg 0.02 Tc 4.089 0 Td (des )Tj 0.0171 Tc -26.718 -1.126 Td (manoeuvres )Tj 0.29 0.294 0.286 rg 0.0152 Tc 5.8 0 Td (d"hyperventilation )Tj 0.353 0.353 0.349 rg 0.0171 Tc 8.594 0 Td (isocapniques )Tj 0.29 0.294 0.286 rg 0.031 Tc 6.16 0 Td (\(HVI\) )Tj 0.0442 Tc 3.379 0 Td (dans )Tj 0.353 0.353 0.349 rg 0.02 Tc 2.785 0 Td (des )Tj 0.0269 Tc -26.785 -1.068 Td (conditions )Tj 0.29 0.294 0.286 rg 0.0158 Tc 4.8 0 Td (climatiques )Tj 0.0196 Tc 5.216 0 Td (identiques )Tj 0.353 0.353 0.349 rg 0.0442 Tc 4.68 0 Td (dans )Tj -0.035 Tc 7.8836 0 0 8.1 447.77 383.76 Tm (le )Tj 0.0423 Tc 8.1 0 0 8.1 456.4 383.76 Tm (cadre )Tj 0.0141 Tc 2.726 0 Td (de )Tj 0.05 Tc 8.1078 0 0 8.1 489.59 383.76 Tm (notre )Tj 0.019 Tc 8.1 0 0 8.1 511.11 383.76 Tm (enquete )Tj 0.451 0.451 0.447 rg 0 Tc -24.891 -1.125 Td (s)Tj 0.29 0.294 0.286 rg 0.05 Tc 8.1596 0 0 8.1 312.96 374.65 Tm (ur )Tj 0.353 0.353 0.349 rg -0.0053 Tc 8.1 0 0 8.1 322.48 374.65 Tm (ces )Tj 0.29 0.294 0.286 rg 0.0113 Tc 1.599 0 Td (facteurs )Tj 0.0274 Tc 3.557 0 Td (determinants )Tj 0.353 0.353 0.349 rg 0.0172 Tc 5.809 0 Td (interactifs )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.2927 0 0 8.1 447.28 374.65 Tm (de )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf -0.035 Tc 7.2698 0 0 8.1 457.87 374.65 Tm (Ia )Tj EMC ET BT /T1_0 1 Tf 0.0144 Tc 8.1 0 0 8.1 466.49 374.65 Tm (gravite )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.2927 0 0 8.1 491.92 374.65 Tm (de )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 7.9307 0 0 8.1 502.51 374.65 Tm (Ia )Tj EMC ET BT /T1_0 1 Tf 0.0154 Tc 8.1 0 0 8.1 511.19 374.65 Tm (reponse )Tj 0.0179 Tc -24.898 -1.068 Td (astltmatique. )Tj 0.0469 Tc 5.881 0 Td (Nous )Tj 0.353 0.353 0.349 rg 0.0272 Tc 2.652 0 Td (avons )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0351 Tc 8.1 0 0 8.1 401.7347 365.9992 Tm (trouve )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0317 Tc 8.1 0 0 8.1 426.6341 365.9992 Tm (que, )Tj 0.0121 Tc 2.193 0 Td (accompli )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 12.8 0 0 12.8 478.43 366 Tm (a )Tj EMC ET BT /T1_0 1 Tf -0.0096 Tc 8.1 0 0 8.1 485.68 366 Tm (des )Tj 0.0067 Tc 1.786 0 Td (niveaux )Tj 0.0141 Tc 3.606 0 Td (de )Tj 0.012 Tc -27.074 -1.125 Td (ventilation )Tj 0.353 0.353 0.349 rg 0.0237 Tc 4.744 0 Td (peu )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0027 Tc 8.1 0 0 8.1 362.3008 356.8875 Tm (eleves )Tj EMC ET BT /T1_0 1 Tf 0.0029 Tc 8.1 0 0 8.1 384.8836 356.8875 Tm (l'exercice )Tj 0 Tc 4.028 0 Td (a )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0132 Tc 8.1 0 0 8.1 423.7474 356.8875 Tm (declenchc )Tj EMC ET BT /T1_0 1 Tf 0.0195 Tc 8.1 0 0 8.1 459.3469 356.8875 Tm (une )Tj 0.0169 Tc 1.777 0 Td (response )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0258 Tc 8.1 0 0 8.1 505.3468 356.8875 Tm (asthmati\255)Tj EMC ET BT /T1_0 1 Tf 0.0243 Tc 8.1 0 0 8.1 309.505 347.7588 Tm (que )Tj 0.0268 Tc 1.846 0 Td (nettement )Tj 0 Tc 4.447 0 Td (p)Tj 0.188 0.188 0.18 rg 0.583 0 Td (l)Tj 0.29 0.294 0.286 rg 0.0005 Tc 0.246 0 Td (us )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0259 Tc 8.1 0 0 8.1 376.7107 347.7588 Tm (attenuee )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.05 Tc 8.142 0 0 8.1 407.44 347.76 Tm (que )Tj 0.0442 Tc 8.1 0 0 8.1 422.32 347.76 Tm (dans )Tj -0.035 Tc 7.8836 0 0 8.1 441.05 347.76 Tm (le )Tj 0.353 0.353 0.349 rg 0.0244 Tc 8.1 0 0 8.1 448.24 347.76 Tm (cas )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.2927 0 0 8.1 461.2 347.76 Tm (de )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0164 Tc 8.1 0 0 8.1 471.78 347.76 Tm (I'HVI. )Tj EMC ET BT /T1_0 1 Tf 0.0259 Tc 8.1 0 0 8.1 496.7604 347.76 Tm (La )Tj 0.353 0.353 0.349 rg 0.042 Tc 1.299 0 Td (chute )Tj 0.29 0.294 0.286 rg 0.0164 Tc 2.607 0 Td (du )Tj 0.018 Tc -27.015 -1.125 Td (volume )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0144 Tc 8.1 0 0 8.1 336.3885 338.6475 Tm (expire )Tj EMC /Suspect <>BDC 0.353 0.353 0.349 rg 0.0007 Tc 2.844 0 Td (force )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0249 Tc 8.1 0 0 8.1 378.144 338.6475 Tm (en )Tj 0.0195 Tc 1.256 0 Td (une )Tj 0.353 0.353 0.349 rg 0.021 Tc 1.705 0 Td (seconde )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 8.5187 0 0 8.2 430.89 338.65 Tm (\(t. )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 8.2367 0 0 8.1 439.18 338.65 Tm (VEF )Tj 0.353 0.353 0.349 rg 0 Tc 4.8001 0 0 4.8001 456.32 337.21 Tm (1)Tj 0.527 0.3 Td (\) )Tj 0.29 0.294 0.286 rg 8.1 0 0 8.1 463.6 338.65 Tm (a )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0208 Tc 8.1 0 0 8.1 468.0064 338.65 Tm (pres )Tj EMC ET BT /T1_0 1 Tf 0.0019 Tc 8.1 0 0 8.1 483.2668 338.65 Tm (exercice )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0498 Tc 8.1 0 0 8.1 512.0704 338.65 Tm (etait )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0141 Tc 8.1 0 0 8.1 529.3639 338.65 Tm (de )Tj 0.05 Tc 8.772 0 0 8.1 310.26 329.53 Tm (15\2614% )Tj 0.048 Tc 8.1 0 0 8.1 339.85 329.53 Tm (par )Tj 0.0425 Tc 1.657 0 Td (rapport )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0 Tc 12.4 0 0 12.4 380.99 329.53 Tm (a )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.9351 0 0 8.1 387.31 329.53 Tm (27\2613% )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0387 Tc 8.1 0 0 8.1 417.04 329.53 Tm (apres )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.034 Tc 8.1 0 0 8.1 437.7193 329.53 Tm (HVl )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0386 Tc 8.1 0 0 8.1 454.948 329.53 Tm (\(p<0.0002\). )Tj EMC /Suspect <>BDC 0.042 Tc 5.458 0 Td (L'hyperno\267 )Tj EMC /Suspect <>BDC -0.035 Tc 6.1223 0 0 8.1 309.01 320.89 Tm ("ia )Tj EMC ET BT /T1_0 1 Tf 0.0185 Tc 8.1 0 0 8.1 318.64 320.89 Tm (qui )Tj 0.026 Tc 1.719 0 Td (accompagne )Tj 0.29 0.294 0.286 rg 0.0095 Tc 5.572 0 Td (l'exercice )Tj 0.0377 Tc 4.217 0 Td (pouvant )Tj 0.353 0.353 0.349 rg 0.0241 Tc 3.778 0 Td (servir )Tj 0.29 0.294 0.286 rg 0.0141 Tc 2.73 0 Td (de )Tj 0.0135 Tc 1.363 0 Td (declencheur, )Tj 0.0233 Tc 5.638 0 Td (nous )Tj 0.353 0.353 0.349 rg 0.0249 Tc -26.202 -1.127 Td (en )Tj 0.29 0.294 0.286 rg 0.0272 Tc 1.66 0 Td (avons )Tj 0.353 0.353 0.349 rg 0.0166 Tc 3.022 0 Td (conclu )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.142 0 0 8.1 374.32 311.76 Tm (que )Tj 0.353 0.353 0.349 rg 0 Tc 8.1 0 0 8.1 392.09 311.76 Tm (l)Tj 0.451 0.451 0.447 rg 0.294 0 Td (')Tj 0.353 0.353 0.349 rg 0.0019 Tc 0.178 0 Td (exercice )Tj -0.035 Tc 7.9278 0 0 8.1 428.09 311.76 Tm (lui)Tj 0.451 0.451 0.447 rg 0 Tc 8.1 0 0 8.1 436.71 311.76 Tm (-)Tj 0.29 0.294 0.286 rg -0.002 Tc 0.364 0 Td (mcme )Tj 0.353 0.353 0.349 rg 0.0386 Tc 3.075 0 Td (introduit )Tj 0.29 0.294 0.286 rg 0.05 Tc 8.2333 0 0 8.1 499.68 311.76 Tm (un )Tj 0.0286 Tc 8.1 0 0 8.1 513.51 311.76 Tm (facteur )Tj 0.353 0.353 0.349 rg 0.0249 Tc -25.188 -1.067 Td (supplementaire )Tj 0.0185 Tc 6.819 0 Td (qui )Tj -0.0003 Tc 1.779 0 Td (limite )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 7.2698 0 0 8.1 401.71 303.12 Tm (Ia )Tj EMC ET BT /T1_0 1 Tf 0.0154 Tc 8.1 0 0 8.1 411.35 303.12 Tm (reponse )Tj 0.29 0.294 0.286 rg -0.0127 Tc 3.614 0 Td (max.imum )Tj 0.353 0.353 0.349 rg 0.027 Tc 4.615 0 Td (constatee )Tj 0.29 0.294 0.286 rg 0.0147 Tc 4.393 0 Td (tors )Tj 0.0141 Tc 1.948 0 Td (de )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 8.1 0 0 8.1 309.5492 293.9994 Tm (I)Tj 0.451 0.451 0.447 rg 0.233 0 Td (')Tj 0.29 0.294 0.286 rg 0.0194 Tc 0.302 0 Td (HVI. )Tj EMC ET BT /T1_0 1 Tf 0.0419 Tc 8.1 0 0 8.1 335.9228 293.9994 Tm (Cette )Tj 0.0154 Tc 2.912 0 Td (reponse )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0259 Tc 8.1 0 0 8.1 390.6383 293.9994 Tm (attenuee )Tj EMC ET BT 0.353 0.353 0.349 rg /T1_0 1 Tf -0.035 Tc 8.0856 0 0 8.1 424.21 294 Tm (se )Tj ET BT /Suspect <>BDC 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0116 Tc 8.1 0 0 8.1 435.82 294 Tm (manifeste )Tj EMC /Suspect <>BDC 0.353 0.353 0.349 rg 0 Tc 12.8 0 0 12.8 472.67 294 Tm (a )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.02 Tc 8.1 0 0 8.1 481.84 294 Tm (des )Tj 0.0166 Tc 2.023 0 Td (niveaux )Tj 0.353 0.353 0.349 rg 0.0141 Tc 3.843 0 Td (de )Tj 0.0179 Tc -27.133 -1.125 Td (ventilation )Tj 0.0203 Tc 4.863 0 Td (bas )Tj 0.29 0.294 0.286 rg 0.0049 Tc 1.715 0 Td (mais )Tj 0.0183 Tc 2.243 0 Td (est )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf 0.0108 Tc 8.1 0 0 8.1 393.58 284.89 Tm (masquee )Tj EMC ET BT 0.29 0.294 0.286 rg /T1_0 1 Tf 0.0159 Tc 8.1 0 0 8.1 425.6884 284.89 Tm (lorsquc )Tj 0.353 0.353 0.349 rg -0.0053 Tc 3.377 0 Td (ces )Tj 0.29 0.294 0.286 rg 0.0067 Tc 1.609 0 Td (niveaux )Tj -0.035 Tc 7.9626 0 0 8.1 494.77 284.89 Tm (sonL )Tj ET BT /Suspect <>BDC 0.353 0.353 0.349 rg /T1_0 1 Tf -0.0097 Tc 8.1 0 0 8.1 512.08 284.89 Tm (cleves. )Tj EMC ET endstream endobj 36 0 obj <>/Filter/JBIG2Decode/Height 1752/ImageMask true/Length 27348/Name/X/Subtype/Image/Type/XObject/Width 1240>>stream =7 kuȆq Jut]Ggt5ISH3<]رCIh%LR?_}$H6Yetf8qUx{9!dAw}}HSp*hNc!r˄j`FiX՟` ѡS'5udF/HGco{Em9n oFMG3dlNYjUb ~PƾS꫄slS-6ER|K3AZPQud-7" 2/ot_NXHEVn-@\Q 3 Bp6ZG5/ [$̦-nu$*7"<+^!*$L6\E=S0ZU9Sf O\G}lGPׄt"pLDy3WB_BL~ޔՐZ׭ħI!-2M_4)0N6]skE7,JxLV[]{w8~;D8%X K`}F~E86jfdyfoަT|g d¹:j- < j x5HQnvĎi)ܓ *pϡD-(wY;ӻPuX{ [_Uc L2f[߸ G1ؤq6t; ҥ!] \ $L{( M/DC!O}-sʯO'x~+<cJxWΆ'UN"d>(;4G~*V%:+WZq}\gB)iX`MB۸сl[-Θ,Bob 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