抽象
两个乙炔(AC)和二氧化碳可以用于测量有效肺血流量(Q'eff)非侵入性。他们是安全的,在休息和运动过程中的成年人相当准确,但也出现在孩子们一直没有同时比较。采用映众四极杆质谱仪一百零六名健康儿童(男55例,女51例,年龄8-17岁)进行了研究。他们都经历了五次再呼吸演习在休息,然后单次测量后,自行车运动的9分钟再次进行。混合静脉CO2水平通过线性(L)或曲线(C)外推法计算出的任一。在静止时,变化为Q'eff的系数分别为AC 8%,L 20%,和C 16%(P <0.001)。平均静息值分别为:AC 3.2(95%置信区间(95%CI)3.1-3.4)L- 5.1(95%CI 4.6-5.4)和C 4.7(95%CI 4.3-5.1)长x分钟(-1)x m(-2), (p<0.001). Compared to Ac, only 14 and 17% of L and C values, respectively, were +/-0.5 L x min(-1) x m(-2), whilst 41 and 29%, respectively were more than +/-2 L x min(-1) x m(-2). During exercise, median values were: Ac 6.7 (95% CI 6.3-7.0); L 8.0 (95% CI 7.3-8.4); and C 7.2 (95% CI 6.5-7.9) L x min(-1) x m(-2). L was significantly greater than C (p<0.001), but C was similar to Ac (p=0.06). More than 50% of L and C values could not be calculated for various reasons, whereas all 106 Ac values could be calculated. Neither carbon dioxide method is sufficiently reliable to be used in children in a clinical setting. Acetylene was safe, reliable, accurate and preferred.