抽象的
本报告的目的是记录医院环境中慢性阻塞性肺病(COPD)急性加剧中的初始抗生素的模式。根据录取医生,1996年1月期间的一家医院诊断,均急性加剧的所有急性加剧剧集。回顾性审查案例说明。放射线肺炎,支气管扩张和错误编码录取的病例被排除在外。记录症状,微生物培养和初始抗生素疗法。鉴定了一百五十九个患者发作;40被排除在一起,产生119个样品。19例案例不可用,留下100个(84%)发作的样品。八十人在入场时用抗生素治疗;阿莫西霉素是最常规定的,在46个(58%)发作中。在抗生素治疗组中,42例(53%)患者被给予双重治疗,最常见的是一种具有氨基吡啶或头孢菌素的大环内酯抗生素。 Intravenous treatment was used in 22 (28%) cases. The duration of intravenous treatment was >48 h in 12 (15%) cases. A total of 76 sputum samples were analysed from 55 patient episodes: 34 (45%) were culture positive. In 15 (27%) patient episodes, antibiotic therapy was changed or instituted on the basis of culture results. These data suggest that antibiotic treatment is not optimal, with overuse of antibiotics, especially intravenous and dual therapy.