摘要
研究了2个8周的慢性阻塞性肺疾病(COPD)患者康复计划的影响。41名受试者(平均+/-SD) 644.5岁;秒用力呼气量(FEV1) 1.09+/-0.16 L;40.6+/-6.2%的预测被随机分配到有监督的跑步机训练,4天x周(-1)(S组;n=21)或每周4天,1小时步行3或4公里(-1),用计步器自我监测,每周访问以鼓励坚持(SM组;n = 20)。采用慢性呼吸系统疾病问卷(CRQ)和两项跑步机运动试验(增量运动(IT)和恒定运动(CT))对患者进行评估,并通过动脉血乳酸测定测定乳酸阈值以上或70%最大摄氧量(VO2, max)。估计S组和SM组的训练平均工作率分别为69+/-27 W和25+/-5 W。两种类型的训练在CRQ的四个维度上产生了相似的变化。S组患者术后VO2、max和持续时间显著增加(p<0.05), CT结束时乳酸积累、通气、CO2输出(VCO2)、心率(HR)和舒张压(DBP)降低。 They also adopted a deeper slower pattern of breathing during exercise. The SM group showed significant (p<0.05) increases in duration, lower HR and DBP at the end of CT. Significantly (p<0.05) different effects between S and SM programmes were changes in VO2, max 100+/-101 mL x min(-1) versus 5+/-101 mL x min(-1)), duration of the CT (8.1+/-4.4 min versus 3.9+/-4.7 min), VCO2 (-94+/-153 mL x min(-1) versus 48+/-252 mL x min(-1)), lactate accumulation (-1.3+/-2.2 mmol x L(-1) versus 0+/-1.2 mmol x L(-1) and respiratory rate at the end of CT (4.3+/-3.4 min(-1) versus -1+/-4.2 min(-1)). Supervised, intense training yields physiological improvements in severe chronic obstructive pulmonary disease patients not induced by self-monitored training. The self-monitored, less intense training, increases submaximal exercise endurance, although to a lesser degree.