From the authors:
We thank C. Thamrin and co-workers for their interest in our paper and their reflection, which continues the discussion on how to express bronchodilator responsiveness. This has been an important topic of debate for decades in the adult and the paediatric pulmonary field. In their letter, C. Thamrin and co-workers state that if a bronchodilator change is related to anthropometric factors or baseline lung function, these factors should be taken into account.
The worse the baseline lung function the more room for improvement, at least for the asthmatic patient. This has been recognised and translated in the guideline that the bronchodilator response as assessed with forced expiration is …