摘要
许多慢性阻塞性肺疾病(COPD)患者在日常生活活动中遇到问题,包括所谓的无支撑臂抬高(AE)。在本研究中,比较了13名COPD患者(1秒用力呼气量(FEV1)(平均(SD)) 38(13)%的预测)和13名年龄匹配的健康受试者对三种上臂抬高的代谢和呼吸反应模式的可能差异。每位受试者连续进行三种抬臂方式2分钟,其间休息3分钟。在基线期3分钟和整个测量期记录呼吸代谢和呼吸呼吸参数及心率(HR)。经过对COPD患者基线试验结果的显著提高进行调整后,我们发现,与年龄匹配的健康受试者相比,COPD患者的AE(手臂抬高包括恢复)对代谢和呼吸反应的要求更高。手臂抬高导致耗氧量增加(V'O2) (COPD 12%;健康者6%),二氧化碳消除V'CO2 (COPD 15%;健康者10%),分通气V'E (COPD 13%;健康的7%)和心率(COPD 2%;健康的5%)。 A pronounced difference was found in the pattern of metabolic and ventilatory response to arm elevation, i.e. there was an earlier but sluggish V'O2 onset in COPD patients, whereas the healthy subjects demonstrated a sudden peak approximately 30 s after arm elevations. Mutual comparison of the three different types of arm elevation demonstrated a comparable response pattern. Knowledge of the specific response to arm elevations in COPD patients seems essential for interpretation of arm elevation tests in upper extremity rehabilitation programmes.