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12.4799957 332.6399994 787.6799927 cm /Im3 Do Q q 18.2400055 0 0 12.4799957 478.5599976 787.6799927 cm /Im4 Do Q q 18.2400055 0 0 14.3999939 516.9600067 785.7599945 cm /Im5 Do Q q 12.4799957 0 0 30.7200012 0.4799957 679.1999969 cm /Im6 Do Q q 12.9600067 0 0 16.3200073 0 647.5200043 cm /Im7 Do Q q 12.9600067 0 0 15.3600006 0 617.7599945 cm /Im8 Do Q q 12.9600067 0 0 11.0399933 0 0 cm /Im9 Do Q BT 0.243 g /T1_0 1 Tf -0.0295 Tc 3 Tr 10.1 0 0 10.1 60.92 755.29 Tm (408 )Tj 0.05 Tc 9.9034 0 0 7.8001 248.12 755.76 Tm (F.P. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 8.8221 0 0 7.8001 270.68 755.76 Tm (PRIMIANO )Tj EMC ET BT 0.322 g /T1_0 1 Tf 0 Tc 7.8001 0 0 7.8001 321.56 755.76 Tm (E)Tj 0.184 g 0.673 0 Td (T )Tj 0.243 g 0.05 Tc 8.371 0 0 7.8001 336.47 755.76 Tm (AL)Tj 0.439 0.439 0.435 rg 0 Tc 7.8001 0 0 7.8001 349.28 755.76 Tm (. )Tj 0.243 g 0.0328 Tc 10.1 0 0 10.1 60.94 732.24 Tm (the )Tj -0.0171 Tc 1.854 0 Td (wall )Tj -0.0005 Tc 2.274 0 Td (in )Tj 0.0328 Tc 1.337 0 Td (the )Tj 0.0252 Tc 1.855 0 Td (upper )Tj 0.0108 Tc 2.937 0 Td (airways. )Tj 0.184 g 0.05 Tc 10.2656 0 0 10.1 204.87 732.24 Tm (The )Tj 0.243 g 0.0392 Tc 10.1 0 0 10.1 227.06 732.24 Tm (probe )Tj -0.032 Tc 2.984 0 Td (is )Tj 0.0167 Tc 1.186 0 Td (con\255)Tj 0.322 g 0.0246 Tc -20.63 -1.092 Td (st)Tj 0.184 g 0.0236 Tc 0.726 0 Td (ructed )Tj 0.243 g 0.0113 Tc 2.937 0 Td (from )Tj 0 Tc 2.282 0 Td (a )Tj 0.0028 Tc 0.804 0 Td (stainless-steel )Tj 0.0336 Tc (catheter )Tj -0.0144 Tc 9.554 0 Td (\(0.8 )Tj 0.0188 Tc 1.863 0 Td (mm )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0304 Tc 10.1 0 0 10.1 263.4099 721.2108 Tm (O.D.\) )Tj EMC ET BT 0.184 g /T1_0 1 Tf 0.0084 Tc 10.1 0 0 10.1 60.9352 710.1715 Tm (which )Tj -0.032 Tc 3.225 0 Td (is )Tj 0.243 g 0.0248 Tc 1.329 0 Td (constricted )Tj 0.05 Tc 10.7518 0 0 10.1 161.17 710.17 Tm (at )Tj 0.0118 Tc 10.1 0 0 10.1 177.04 710.17 Tm (its )Tj 0.0097 Tc 1.717 0 Td (tip. )Tj 0.05 Tc 10.2656 0 0 10.1 215.43 710.17 Tm (The )Tj 0.0404 Tc 10.1 0 0 10.1 239.42 710.17 Tm (catheter )Tj -0.032 Tc 4.137 0 Td (is )Tj 0.0251 Tc -21.863 -1.046 Td (connected )Tj 0.0333 Tc 4.523 0 Td (to )Tj 0.0328 Tc 1.093 0 Td (the )Tj 0.184 g 0.012 Tc 1.562 0 Td (inlet )Tj 0.243 g 0.05 Tc 11.1292 0 0 10.1 153.97 699.61 Tm (of )Tj 0 Tc 10.1 0 0 10.1 165.02 699.61 Tm (a )Tj 0.0008 Tc 0.768 0 Td (mass )Tj 0.0259 Tc 2.269 0 Td (spectrometer )Tj 0.0169 Tc 5.705 0 Td (\(Perkin\255)Tj 0.0159 Tc -19.099 -1.094 Td (Elmer, )Tj -0.025 Tc 3.488 0 Td (1100 )Tj 0.0222 Tc 2.501 0 Td (MGA\). )Tj 0.184 g 0.05 Tc 10.2656 0 0 10.1 157.35 688.56 Tm (The )Tj 0.243 g /T1_1 1 Tf 9.2738 0 0 9.2 180.41 688.56 Tm (low )Tj /T1_0 1 Tf 0.0212 Tc 10.1 0 0 10.1 201.14 688.56 Tm (pressure )Tj 0.0131 Tc 4.037 0 Td (within )Tj 0.009 Tc 3.278 0 Td (the )Tj 0.0279 Tc -21.251 -1.092 Td (catheter, )Tj 0.0117 Tc 4.325 0 Td (caused )Tj -0.035 Tc 10.0482 0 0 10.1 140.17 677.53 Tm (by )Tj 0.009 Tc 10.1 0 0 10.1 157.42 677.53 Tm (the )Tj 0.02 Tc 1.941 0 Td (constricted )Tj 0.322 g 0.0097 Tc 5.331 0 Td (tip, )Tj 0.243 g 0.0201 Tc 2.095 0 Td (prevents )Tj 0.028 Tc -18.974 -1.046 Td (condensation )Tj 0.05 Tc 10.2564 0 0 10.1 120.86 666.97 Tm (on )Tj 0.0215 Tc 10.1 0 0 10.1 136.24 666.97 Tm (internal )Tj 0.0113 Tc 3.653 0 Td (surfaces )Tj 0.05 Tc 11.1292 0 0 10.1 211.09 666.97 Tm (of )Tj 0.0328 Tc 10.1 0 0 10.1 224.14 666.97 Tm (the )Tj 0.0336 Tc 1.655 0 Td (catheter )Tj 0.05 Tc 10.7518 0 0 10.1 279.25 666.97 Tm (at )Tj 0.0282 Tc 10.1 0 0 10.1 60.46 655.92 Tm (temperatures )Tj 0.036 Tc 5.98 0 Td (above )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 10.1 0 0 10.1 151.5822 655.92 Tm (0)Tj 0.439 0.439 0.435 rg 0.519 0 Td (\260)Tj 0.243 g -0.035 Tc 10.0535 0 0 10.1 160.7 655.92 Tm (C. )Tj EMC ET BT /T1_0 1 Tf 0.0288 Tc 10.1 0 0 10.1 175.14 655.92 Tm (Eliminating )Tj 0.0324 Tc 5.509 0 Td (condensation )Tj 0.0444 Tc -16.871 -1.092 Td (and )Tj 0.0341 Tc 2.043 0 Td (evaporation )Tj /T1_2 1 Tf 0.0459 Tc 9.8 0 0 9.8 137.09 644.89 Tm (in )Tj /T1_0 1 Tf 0.0328 Tc 10.1 0 0 10.1 150.22 644.89 Tm (the )Tj 0.0336 Tc 1.75 0 Td (catheter )Tj 0.05 Tc 10.3398 0 0 10.1 206.77 644.89 Tm (and )Tj 0.0325 Tc 10.1 0 0 10.1 227.5 644.89 Tm (mass )Tj 0.0259 Tc 2.554 0 Td (spectro\255)Tj 0.015 Tc -19.093 -1.046 Td (meter )Tj 0.0471 Tc 2.655 0 Td (in )Tj 0.322 g 0 Tc 1.194 0 Td (t)Tj 0.184 g -0.0108 Tc 0.334 0 Td (his )Tj 0.243 g 0.0014 Tc 1.473 0 Td (way )Tj 0.184 g 0.0142 Tc 2.037 0 Td (improves )Tj 0.243 g 0.0328 Tc 4.188 0 Td (the )Tj 0.0162 Tc 1.604 0 Td (step-response )Tj 0.0114 Tc 6 0 Td (time )Tj 0.05 Tc 11.1292 0 0 10.1 278.77 634.33 Tm (of )Tj 0.0328 Tc 10.1 0 0 10.1 60.46 623.29 Tm (the )Tj 0.0167 Tc 1.521 0 Td (mass )Tj 0.322 g 0.0216 Tc 2.364 0 Td (spectrometer )Tj 0.243 g 0.0015 Tc 5.706 0 Td (for )Tj 0.0288 Tc 1.483 0 Td (water )Tj 0.0273 Tc 2.565 0 Td (vapour. )Tj 0.0135 Tc 3.517 0 Td (Also, )Tj 0 Tc 2.511 0 Td (a )Tj 0.184 g 0.0157 Tc 0.761 0 Td (lead\255)Tj 0.243 g 0.0288 Tc -20.484 -1.094 Td (compensating )Tj -0.0116 Tc 6.225 0 Td (filter )Tj 0.0094 Tc 2.291 0 Td (was )Tj 0.0188 Tc 1.94 0 Td (applied )Tj 0.0333 Tc 3.477 0 Td (to )Tj 0.0328 Tc 1.236 0 Td (the )Tj 0.0288 Tc 1.664 0 Td (water )Tj 0.0447 Tc 2.708 0 Td (vapour )Tj 0.0031 Tc -19.497 -1.046 Td (signal )Tj 0.0333 Tc 3.149 0 Td (to )Tj 0.184 g 0.0259 Tc 1.467 0 Td (improve )Tj 0.243 g 0.0328 Tc 4.141 0 Td (the )Tj 0.184 g 0.0301 Tc 1.941 0 Td (dynamic )Tj 0.0069 Tc 4.286 0 Td (response. )Tj 0.243 g 0.0179 Tc 4.553 0 Td (Conse\255)Tj 0.0264 Tc -19.58 -1.092 Td (quently, )Tj 0.0328 Tc 3.715 0 Td (the )Tj 0.0227 Tc 1.512 0 Td (90% )Tj 0.0162 Tc 2.231 0 Td (step-response )Tj 0.0114 Tc 5.905 0 Td (time )Tj 0.184 g 0.0252 Tc 2.082 0 Td (for )Tj 0.243 g 0.0288 Tc 1.483 0 Td (water )Tj 0.0447 Tc 2.613 0 Td (vapour )Tj -0.032 Tc -19.539 -1.093 Td (is )Tj 0.0231 Tc 0.949 0 Td (approximately )Tj -0.0277 Tc 6.372 0 Td (250 )Tj -0.016 Tc 1.762 0 Td (msec. )Tj 0.184 g 0.0396 Tc 2.607 0 Td (The )Tj 0.243 g 0.0162 Tc 1.944 0 Td (step-response )Tj 0.0252 Tc 5.944 0 Td (for )Tj 0.0271 Tc 1.522 0 Td (dry )Tj 0.0067 Tc -21.1 -1.094 Td (gas )Tj -0.032 Tc 1.712 0 Td (is )Tj 0.184 g -0.019 Tc 0.95 0 Td (less )Tj 0.243 g 0.0294 Tc 1.86 0 Td (than )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 9.8926 0 0 10.1 128.3 568.56 Tm (100 )Tj EMC ET BT /T1_0 1 Tf -0.0041 Tc 10.1 0 0 10.1 145.9 568.56 Tm (msec. )Tj 0.0289 Tc -7.56 -1.046 Td (Local )Tj 0.0067 Tc 3.134 0 Td (gas )Tj 0.0444 Tc 2.043 0 Td (and )Tj 0.0194 Tc 2.281 0 Td (airway )Tj -0.0012 Tc 3.526 0 Td (wall )Tj 0.0282 Tc 2.47 0 Td (temperatures )Tj 0.004 Tc 6.132 0 Td (were )Tj 0.0173 Tc -20.532 -1.092 Td (measured )Tj 0.0076 Tc 4.47 0 Td (by )Tj 0.0231 Tc 1.423 0 Td (micro-bead )Tj 0.026 Tc 5.228 0 Td (thermistors )Tj 0.184 g 0.0437 Tc 5.18 0 Td (mounted )Tj 0.243 g 0.05 Tc 10.2564 0 0 10.1 266.78 546.97 Tm (on )Tj 0 Tc 10.1 0 0 10.1 282.14 546.97 Tm (a )Tj 0.0273 Tc -22.04 -1.094 Td (protective )Tj 0.0148 Tc 4.693 0 Td (cage )Tj 0.05 Tc 10.7518 0 0 10.1 131.41 535.92 Tm (at )Tj 0.009 Tc 10.1 0 0 10.1 144.94 535.92 Tm (the )Tj 0.0207 Tc 1.853 0 Td (tip )Tj 0.05 Tc 11.1292 0 0 10.1 179.89 535.92 Tm (of )Tj 0.009 Tc 10.1 0 0 10.1 194.38 535.92 Tm (the )Tj 0.0289 Tc 1.762 0 Td (probe. )Tj 0.184 g 0.05 Tc 10.2656 0 0 10.1 244.71 535.92 Tm (The )Tj 0.243 g 0.0198 Tc 10.1 0 0 10.1 266.74 535.92 Tm (step\255)Tj 0.184 g 0.0165 Tc -20.47 -1.046 Td (response )Tj 0.243 g 0.05 Tc 11.1292 0 0 10.1 99.73 525.36 Tm (of )Tj 0.184 g 0.009 Tc 10.1 0 0 10.1 111.82 525.36 Tm (the )Tj 0.243 g 0.0298 Tc 1.616 0 Td (thermistor )Tj 0.0252 Tc 4.649 0 Td (for )Tj 0.0067 Tc 1.57 0 Td (gas )Tj 0.0318 Tc 1.718 0 Td (temperature )Tj -0.032 Tc 5.364 0 Td (is )Tj 0.184 g -0.019 Tc 0.997 0 Td (less )Tj 0.322 g 0.0453 Tc -21.047 -1.092 Td (than )Tj 0.184 g -0.035 Tc 9.8926 0 0 10.1 82.7 514.33 Tm (120 )Tj 0.243 g -0.0013 Tc 10.1 0 0 10.1 99.34 514.33 Tm (msec )Tj 0.184 g -0.0005 Tc 2.323 0 Td (in )Tj 0.243 g 0.0004 Tc 1.04 0 Td (still )Tj 0.0198 Tc 1.762 0 Td (air; )Tj 0.322 g 0.05 Tc 10.215 0 0 10.1 168.46 514.33 Tm (that )Tj 0.243 g 11.1292 0 0 10.1 188.05 514.33 Tm (of )Tj 0.0328 Tc 10.1 0 0 10.1 199.66 514.33 Tm (the )Tj -0.0012 Tc 1.522 0 Td (wall )Tj 0.0318 Tc 2.043 0 Td (temperature )Tj 0.184 g 0.0298 Tc -17.394 -1.094 Td (thermistor )Tj 0.243 g -0.035 Tc 9.3682 0 0 10.1 108.88 503.28 Tm (is )Tj 0.184 g -0.019 Tc 10.1 0 0 10.1 119.91 503.28 Tm (less )Tj 0.243 g 0.0294 Tc 1.908 0 Td (than )Tj ET BT /Suspect <>BDC 0.184 g /T1_0 1 Tf -0.035 Tc 9.8926 0 0 10.1 163.34 503.28 Tm (100 )Tj EMC ET BT 0.243 g /T1_0 1 Tf -0.0013 Tc 10.1 0 0 10.1 182.38 503.28 Tm (msec )Tj 0.184 g -0.0005 Tc 2.465 0 Td (in )Tj 0.243 g 0.0206 Tc 1.243 0 Td (water. )Tj 0.184 g 0.0316 Tc 3.034 0 Td (Temper\255)Tj 0.243 g 0.05 Tc 10.1056 0 0 10.1 59.42 492.72 Tm (ature )Tj 0.0444 Tc 10.1 0 0 10.1 84.38 492.72 Tm (and )Tj 0.0407 Tc 1.815 0 Td (water )Tj 0.0447 Tc 2.613 0 Td (vapour )Tj 0.0188 Tc 3.267 0 Td (steady-state )Tj 0.0276 Tc 5.184 0 Td (calibrations )Tj 0.004 Tc 5.237 0 Td (were )Tj 0.0144 Tc -20.588 -1.092 Td (established )Tj 0.0138 Tc 4.952 0 Td (relative )Tj 0.0333 Tc 3.468 0 Td (to )Tj 0 Tc 1.133 0 Td (a )Tj 0.0293 Tc 0.76 0 Td (dew-point )Tj 0.184 g 0.0273 Tc 4.619 0 Td (hygrometer )Tj 0.243 g 0.0279 Tc 5.169 0 Td (\(Gen\255)Tj 0.0148 Tc -20.102 -1.093 Td (eral )Tj 0.0271 Tc 1.953 0 Td (Eastern, )Tj 0.0276 Tc 3.803 0 Td (Model )Tj -0.035 Tc 10.0023 0 0 10.1 149.41 470.65 Tm (1100 )Tj 0.0153 Tc 10.1 0 0 10.1 171.82 470.65 Tm (AP\). )Tj 0.184 g 0.05 Tc 10.2656 0 0 10.1 69.03 459.61 Tm (The )Tj 0.243 g 0.0242 Tc 10.1 0 0 10.1 90.23 459.61 Tm (rate )Tj 0.05 Tc 11.1292 0 0 10.1 109.81 459.61 Tm (of )Tj 0.0275 Tc 10.1 0 0 10.1 122.3 459.61 Tm (change )Tj 0.05 Tc 11.1292 0 0 10.1 156.37 459.61 Tm (of )Tj 0.184 g 0.0306 Tc 10.1 0 0 10.1 168.87 459.61 Tm (lung )Tj 0.243 g 0.01 Tc 2.241 0 Td (volume )Tj -0.0144 Tc 3.47 0 Td (was )Tj 0.0232 Tc 1.939 0 Td (evaluated )Tj 0.0293 Tc -18.534 -1.046 Td (continuously )Tj 0.0076 Tc 5.714 0 Td (by )Tj 0.0135 Tc 1.272 0 Td (differentiating )Tj 0 Tc 6.131 0 Td (a )Tj 0.0126 Tc 0.709 0 Td (signal )Tj 0.0321 Tc 2.665 0 Td (corresponding )Tj 0.05 Tc 10.4772 0 0 10.1 59.49 438 Tm (to )Tj 0.0275 Tc 10.1 0 0 10.1 70.46 438 Tm (change )Tj 0.05 Tc 10.5727 0 0 10.1 103.1 438 Tm (of )Tj 0.0306 Tc 10.1 0 0 10.1 114.15 438 Tm (lung )Tj 0.0063 Tc 2.098 0 Td (volume. )Tj 0.0313 Tc 3.605 0 Td (This )Tj 0.0031 Tc 2.086 0 Td (signal )Tj 0.0094 Tc 2.722 0 Td (was )Tj 0.0343 Tc 1.845 0 Td (obtained )Tj 0.086 g 0 Tc 3.947 0 Td (i)Tj 0.184 g 0.245 0 Td (n )Tj 0.243 g 0.0183 Tc -21.969 -1.092 Td (some )Tj 0.0124 Tc 2.804 0 Td (subjects )Tj 0.0076 Tc 3.959 0 Td (by )Tj 0.0166 Tc 1.708 0 Td (variable )Tj 0.184 g 0.0228 Tc 3.986 0 Td (inductance )Tj 0.243 g 0.0252 Tc 5.234 0 Td (transducers )Tj 0.016 Tc -17.689 -1.093 Td (\(Respitrace\) )Tj 0.05 Tc 10.3398 0 0 10.1 114.61 415.93 Tm (and )Tj -0.035 Tc 9.9195 0 0 10.1 134.8 415.93 Tm (in )Tj 0.0385 Tc 10.1 0 0 10.1 146.3 415.93 Tm (others )Tj -0.035 Tc 10.0482 0 0 10.1 177.13 415.93 Tm (by )Tj 0.0241 Tc 10.1 0 0 10.1 191.02 415.93 Tm (mercury )Tj 0.0365 Tc 3.838 0 Td (strain )Tj 0.0087 Tc 2.809 0 Td (gauges )Tj 0.0348 Tc -19.726 -1.093 Td (\(Parks )Tj -0.0154 Tc 3.095 0 Td (Elec. )Tj 0.0245 Tc 2.376 0 Td (Lab., )Tj 0.184 g 0.0276 Tc 2.52 0 Td (Model )Tj 0.243 g -0.0186 Tc 3.041 0 Td (270\) )Tj 0.0129 Tc 2.147 0 Td (placed )Tj 0.05 Tc 10.2564 0 0 10.1 222.14 404.89 Tm (on )Tj 0.0328 Tc 10.1 0 0 10.1 236.62 404.89 Tm (the )Tj 0.0392 Tc 1.617 0 Td (rib )Tj 0.0148 Tc 1.464 0 Td (cage )Tj 0.05 Tc 10.3398 0 0 10.1 58.93 393.84 Tm (and )Tj 0.0265 Tc 10.1 0 0 10.1 77.66 393.84 Tm (abdomen. )Tj 0.0249 Tc 4.472 0 Td (Both )Tj 0.05 Tc 11.1292 0 0 10.1 145.81 393.84 Tm (of )Tj 0.0104 Tc 10.1 0 0 10.1 157.42 393.84 Tm (these )Tj 0.0138 Tc 2.376 0 Td (techniques, )Tj 0.0243 Tc 4.935 0 Td (calibrated )Tj 0.0076 Tc 4.478 0 Td (by )Tj 0.0271 Tc -21.531 -1.092 Td (having )Tj 0.0328 Tc 3.136 0 Td (the )Tj 0.0238 Tc 1.556 0 Td (subject )Tj 0.0266 Tc 3.294 0 Td (breathe )Tj 0.0341 Tc 3.362 0 Td (either )Tj 0.0418 Tc 2.712 0 Td (into )Tj 0 Tc 1.994 0 Td (a )Tj 0.0298 Tc 0.756 0 Td (spirometer )Tj 0.05 Tc 10.5727 0 0 10.1 277.34 382.81 Tm (or )Tj 0.0365 Tc 10.1 0 0 10.1 59.02 372.25 Tm (through )Tj 0 Tc 3.889 0 Td (a )Tj 0.0292 Tc 0.962 0 Td (pneumotachometer, )Tj 0.004 Tc 8.932 0 Td (were )Tj 0.05 Tc 11.1292 0 0 10.1 222.61 372.25 Tm (of )Tj 0.039 Tc 10.1 0 0 10.1 236.06 372.25 Tm (comparable )Tj 0.0138 Tc -17.537 -1.093 Td (accuracy. )Tj 0.184 g 0.0396 Tc 0.951 -1.094 Td (The )Tj 0.243 g 0.0339 Tc 1.95 0 Td (instrument )Tj 0.0165 Tc 4.902 0 Td (response )Tj 0.0064 Tc 3.944 0 Td (times )Tj 0.0015 Tc 2.51 0 Td (for )Tj -0.0177 Tc 1.522 0 Td (all )Tj 0.025 Tc 1.283 0 Td (continuously )Tj 0.184 g 0.0173 Tc -17.053 -1.093 Td (measured )Tj 0.243 g 0.0134 Tc 4.515 0 Td (variables )Tj 0.004 Tc 4.278 0 Td (were )Tj -0.0051 Tc 2.458 0 Td (sufficiently )Tj 0.0199 Tc 5.041 0 Td (fast )Tj 0.0333 Tc 2.1 0 Td (to )Tj 0.0317 Tc 1.382 0 Td (permit )Tj 0.0154 Tc -19.773 -1.092 Td (resolution )Tj 0.05 Tc 11.1292 0 0 10.1 105.97 328.09 Tm (of )Tj 0.0359 Tc 10.1 0 0 10.1 119.44 328.09 Tm (intra-breath )Tj 0.0163 Tc 5.51 0 Td (events )Tj /T1_2 1 Tf 0.05 Tc 9.9508 0 0 9.9 206.2 328.09 Tm ([I )Tj 0.184 g /T1_0 1 Tf -0.0184 Tc 10.1 0 0 10.1 214.95 328.09 Tm (l]. )Tj 0.0389 Tc 1.383 0 Td (Furthermore, )Tj 0.243 g 0.009 Tc -16.822 -1.046 Td (the )Tj 0.0127 Tc 1.902 0 Td (wave-shapes )Tj 0.0238 Tc 5.932 0 Td (observed )Tj 0.0406 Tc 4.42 0 Td (during )Tj 0.035 Tc 3.477 0 Td (most )Tj 0.184 g 0.0345 Tc 2.759 0 Td (breathing )Tj 0.243 g 0.0238 Tc -18.538 -1.093 Td (manoeuvres )Tj 0.0171 Tc 5.799 0 Td (had )Tj 0.0316 Tc 2.221 0 Td (substantial )Tj 0.0181 Tc 5.339 0 Td (periods )Tj 0.05 Tc 11.6856 0 0 10.1 231.25 306.49 Tm (of )Tj 0.0089 Tc 10.1 0 0 10.1 247.67 306.49 Tm (relatively )Tj 0.0365 Tc -18.734 -1.094 Td (constant )Tj 0.0012 Tc 4.095 0 Td (values, )Tj 0.0392 Tc 3.267 0 Td (so )Tj 0.05 Tc 10.215 0 0 10.1 146.86 295.44 Tm (that )Tj 0.0185 Tc 10.1 0 0 10.1 168.94 295.44 Tm (transients )Tj 0.05 Tc 10.7518 0 0 10.1 213.97 295.44 Tm (at )Tj 0.0328 Tc 10.1 0 0 10.1 227.02 295.44 Tm (the )Tj 0.0184 Tc 1.761 0 Td (beginning )Tj 0.0444 Tc -18.45 -1.092 Td (and )Tj 0.025 Tc 2.043 0 Td (end )Tj 0.05 Tc 10.5727 0 0 10.1 99.74 284.41 Tm (of )Tj 0.0328 Tc 10.1 0 0 10.1 113.26 284.41 Tm (the )Tj 0.0203 Tc 1.762 0 Td (phases )Tj 0.05 Tc 10.5727 0 0 10.1 164.06 284.41 Tm (of )Tj 0 Tc 10.1 0 0 10.1 177.5 284.41 Tm (a )Tj 0.035 Tc 1.009 0 Td (breath )Tj 0.0322 Tc 3.126 0 Td (could )Tj 0.0171 Tc 2.862 0 Td (be )Tj 0.0039 Tc 1.414 0 Td (easily )Tj 0.184 g 0.019 Tc -20.197 -1.047 Td (discriminated )Tj 0.243 g 0.0444 Tc 6.036 0 Td (and )Tj 0.0183 Tc 1.901 0 Td (analysed )Tj 0.0289 Tc 3.992 0 Td (appropriately. )Tj /T1_3 1 Tf 0.0174 Tc -11.912 -2.708 Td (Experiments )Tj /T1_0 1 Tf 0.0454 Tc 0.941 -1.663 Td (Water )Tj 0.0447 Tc 3.423 0 Td (vapour )Tj 0.028 Tc 3.853 0 Td (partial )Tj 0.0144 Tc 3.612 0 Td (pressure )Tj -0.0144 Tc 4.274 0 Td (was )Tj 0.184 g 0.0241 Tc 2.375 0 Td (measured )Tj 0.243 g 0.0228 Tc -18.547 -1.046 Td (simultaneously )Tj 0.0115 Tc 6.571 0 Td (with )Tj 0.0305 Tc 2.083 0 Td (gas )Tj 0.184 g 0.0444 Tc 1.615 0 Td (and )Tj 0.243 g 0.0146 Tc 1.815 0 Td (wall )Tj 0.0282 Tc 1.995 0 Td (temperatures )Tj 0.0406 Tc 5.695 0 Td (during )Tj 0.0244 Tc -19.762 -1.093 Td (three )Tj 0.0345 Tc 2.664 0 Td (breathing )Tj 0.0384 Tc 4.563 0 Td (patterns )Tj 0.0167 Tc 3.978 0 Td (\(quiet, )Tj 0.0205 Tc 3.242 0 Td (tidal )Tj 0.0097 Tc 2.424 0 Td (volume; )Tj 0.0118 Tc 3.888 0 Td (fast, )Tj 0.0169 Tc -20.771 -1.093 Td (shallow )Tj 0.0224 Tc 3.96 0 Td (panting; )Tj 0.0065 Tc 4.166 0 Td (slow, )Tj 0.184 g 0.0157 Tc 2.904 0 Td (large )Tj 0.243 g -0.0014 Tc 2.811 0 Td (volume\). )Tj 0.184 g 0.05 Tc 10.4358 0 0 10.1 242.35 197.05 Tm (For )Tj 0.243 g 0.0192 Tc 10.1 0 0 10.1 265.42 197.05 Tm (most )Tj 0.0093 Tc -20.543 -1.093 Td (subjects, )Tj 0.0328 Tc 3.861 0 Td (the )Tj 0.0357 Tc 1.512 0 Td (fast )Tj 0.0258 Tc 1.809 0 Td (inspiration )Tj 0.003 Tc 4.847 0 Td (lasted )Tj 0.0463 Tc 2.613 0 Td (0.4-0.6 )Tj -0.035 Tc 9.5089 0 0 10.1 239.87 186.01 Tm (s; )Tj 0.184 g 0.0328 Tc 10.1 0 0 10.1 249.1 186.01 Tm (the )Tj 0.243 g 0.0261 Tc 1.513 0 Td (quiet )Tj 0.0306 Tc -20.481 -1.047 Td (inspiration )Tj 0.184 g -0.035 Tc 9.9586 0 0 10 108.61 175.44 Tm (1.2)Tj 0.322 g 0 Tc 10 0 0 10 119.88 175.44 Tm (-)Tj 0.184 g -0.035 Tc 9.9586 0 0 10 126.85 175.44 Tm (1.5 )Tj 0.322 g 9.5089 0 0 10.1 141.95 175.44 Tm (s; )Tj 0.243 g 0.0328 Tc 10.1 0 0 10.1 152.14 175.44 Tm (the )Tj -0.0031 Tc 1.604 0 Td (slow )Tj 0.0258 Tc 2.24 0 Td (inspiration )Tj 0.05 Tc 10.8621 0 0 10 240.41 175.44 Tm (2-5 )Tj -0.035 Tc 9.9525 0 0 10.1 259.54 175.44 Tm (s. )Tj 0.05 Tc 10.2656 0 0 10.1 269.19 175.44 Tm (The )Tj 0.0292 Tc 10.1 0 0 10.1 57.49 164.41 Tm (estimated )Tj 0.015 Tc 4.706 0 Td (average )Tj 0.184 g -0.0135 Tc 3.849 0 Td (fiows)Tj 0.322 g 0 Tc 2.229 0 Td (, )Tj 0.243 g 0.0345 Tc 0.861 0 Td (as )Tj 0.05 Tc 10.2654 0 0 10.1 190.46 164.41 Tm (an )Tj 0.0341 Tc 10.1 0 0 10.1 207.26 164.41 Tm (approximatiop )Tj 0.322 g 0.0333 Tc 6.947 0 Td (to )Tj 0.243 g 0.0354 Tc -21.766 -1.093 Td (minute )Tj 0.0215 Tc 3.659 0 Td (ventilation, )Tj -0.0119 Tc 5.561 0 Td (were )Tj 0.184 g -0.035 Tc 9.9195 0 0 10.1 177.52 153.37 Tm (in )Tj 0.243 g 0.0328 Tc 10.1 0 0 10.1 192.94 153.37 Tm (the )Tj 0.0156 Tc 2.045 0 Td (range )Tj 0.05 Tc 11.1292 0 0 10.1 243.73 153.37 Tm (of )Tj ET BT /Suspect <>BDC 0.184 g /T1_0 1 Tf -0.035 Tc 9.6688 0 0 10.1 260.79 153.37 Tm (10)Tj 0.439 0.439 0.435 rg 0 Tc 10.1 0 0 10.1 270.12 153.37 Tm (-)Tj 0.243 g -0.035 Tc 9.8266 0 0 10.1 276.37 153.37 Tm (30 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 10.5026 0 0 10.1 57.42 142.8 Tm (I\267 )Tj EMC ET BT /T1_0 1 Tf 0.0331 Tc 10.1 0 0 10.1 65.26 142.8 Tm (min )Tj ET BT /Suspect <>BDC 0.439 0.439 0.435 rg /T1_2 1 Tf 0 Tc 5.9001 0 0 5.9001 82.99 142.8 Tm (-)Tj 0.243 g 0.05 Tc 11.3219 0 0 5.9001 89.07 142.8 Tm (l. )Tj EMC ET BT 0.184 g /T1_0 1 Tf 10.2656 0 0 10.1 99.75 142.8 Tm (The )Tj 0.243 g 0.021 Tc 10.1 0 0 10.1 121.42 142.8 Tm (measurements )Tj 0.004 Tc 6.417 0 Td (were )Tj 0.0193 Tc 2.424 0 Td (repeated )Tj 0.05 Tc 10.7518 0 0 10.1 251.41 142.8 Tm (at )Tj 0.0244 Tc 10.1 0 0 10.1 264.46 142.8 Tm (three )Tj 0.184 g 0.0264 Tc -20.49 -1.093 Td (locations )Tj 0.243 g 0.001 Tc 4.227 0 Td (\(in )Tj 0.0328 Tc 1.578 0 Td (the )Tj 0.0271 Tc 1.762 0 Td (pharynx, )Tj 0.184 g -0.0005 Tc 4.172 0 Td (in )Tj 0.243 g 0.0328 Tc 1.242 0 Td (the )Tj 0.05 Tc 10.1253 0 0 10.1 205.9 131.76 Tm (mouth )Tj 10.7518 0 0 10.1 237.97 131.76 Tm (at )Tj 0.0328 Tc 10.1 0 0 10.1 251.02 131.76 Tm (the )Tj 0.184 g 0.0083 Tc 1.704 0 Td (lips, )Tj 0.243 g 0.0444 Tc -20.864 -1.093 Td (and )Tj 0.184 g 0.0471 Tc 1.95 0 Td (in )Tj 0.243 g 0.0328 Tc 1.242 0 Td (the )Tj 0.0083 Tc 1.712 0 Td (nose )Tj 0.05 Tc 10.7518 0 0 10.1 129.97 120.72 Tm (at )Tj 0.184 g 0.0328 Tc 10.1 0 0 10.1 142.54 120.72 Tm (the )Tj 0.243 g 0.0257 Tc 1.664 0 Td (nares\) )Tj 0.049 Tc 2.937 0 Td (for )Tj 0.0328 Tc 1.672 0 Td (the )Tj 0.0373 Tc 1.651 0 Td (same )Tj 0.184 g 0.0321 Tc 2.535 0 Td (patterns. )Tj 0.0226 Tc -18.827 -1.093 Td (Respired )Tj 0.243 g 0.0067 Tc 3.988 0 Td (gas )Tj 0.0221 Tc 1.718 0 Td (moved )Tj 0.0246 Tc 3.128 0 Td (either )Tj 0.0365 Tc 2.765 0 Td (through )Tj 0.0328 Tc 3.659 0 Td (the )Tj 0.0083 Tc 1.617 0 Td (nose )Tj 0.0115 Tc 2.186 0 Td (with )Tj 0.0328 Tc 2.185 0 Td (the )Tj 0.0398 Tc -21.291 -1.093 Td (mouth )Tj 0.0069 Tc 3.224 0 Td (closed )Tj 0.05 Tc 10.5727 0 0 10.1 121.34 98.64 Tm (or )Tj 0.0444 Tc 10.1 0 0 10.1 135.34 98.64 Tm (through )Tj 0.184 g 0.0328 Tc 3.897 0 Td (the )Tj 0.0398 Tc 1.758 0 Td (mouth )Tj 0.0115 Tc 3.233 0 Td (with )Tj 0.243 g 0.0328 Tc 2.328 0 Td (the )Tj 0.184 g 0.0241 Tc 1.759 0 Td (nose )Tj 0.243 g 0.0094 Tc -20.671 -1.046 Td (blocked. )Tj 0.05 Tc 10.2656 0 0 10.1 97.83 88.08 Tm (The )Tj 0.0249 Tc 10.1 0 0 10.1 119.38 88.08 Tm (studies )Tj 0.0198 Tc 3.34 0 Td (were )Tj 0.0193 Tc 2.471 0 Td (repeated )Tj 0.184 g 0.0252 Tc 4.03 0 Td (for )Tj 0.243 g 0.0358 Tc 1.72 0 Td (two )Tj 0.016 Tc 2.032 0 Td (sets )Tj 0.05 Tc 11.1292 0 0 10.1 276.85 88.08 Tm (of )Tj 0.0196 Tc 10.1 0 0 10.1 57.52 76.57 Tm (inhaled )Tj 0.0305 Tc 3.326 0 Td (gas )Tj 0.184 g 0.0186 Tc 1.718 0 Td (temperatures: )Tj 0.036 Tc 6.028 0 Td (ambient )Tj 0.243 g 0.05 Tc 10.2772 0 0 10.1 206.76 76.57 Tm (\(22\2612\260C\) )Tj 0.0444 Tc 10.1 0 0 10.1 252.38 76.57 Tm (and )Tj 0.05 Tc 10.1377 0 0 10.1 271.19 76.57 Tm (hot )Tj 0 Tc 10.1 0 0 10.1 311.88 732.24 Tm (\( )Tj -0.0342 Tc 0.341 0 Td (48 )Tj 0.322 g /T1_2 1 Tf 0 Tc 12.8 0 0 12.8 326.74 732.24 Tm (\261 )Tj ET BT /Suspect <>BDC 0.243 g /T1_0 1 Tf 10.1 0 0 10.1 334.98 732.24 Tm (2)Tj 0.439 0.439 0.435 rg 0.467 0 Td (\260)Tj 0.243 g -0.0196 Tc 0.432 0 Td (C\). )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 10.2656 0 0 10.1 359.43 732.24 Tm (The )Tj 0.0117 Tc 10.1 0 0 10.1 380.08 732.24 Tm (inhaled )Tj 0.0288 Tc 3.381 0 Td (water )Tj 0.0447 Tc 2.708 0 Td (vapour )Tj 0.028 Tc 3.331 0 Td (pressure )Tj 0.0152 Tc 3.846 0 Td (varied )Tj -0.0005 Tc -20.014 -1.092 Td (in )Tj 0.0328 Tc 1.147 0 Td (the )Tj 0.0156 Tc 1.664 0 Td (range )Tj 0.05 Tc 11.1292 0 0 10.1 366.61 721.21 Tm (of )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0036 Tc 10.1 0 0 10.1 378.62 721.21 Tm (0.4)Tj 0.694 g 0 Tc 1.234 0 Td (-)Tj 0.243 g -0.035 Tc 9.8991 0 0 10.1 398.32 721.21 Tm (l.O )Tj EMC /Suspect <>BDC 0.0113 Tc 10.1 0 0 10.1 413.74 721.21 Tm (kPa)Tj 0.086 g 0 Tc 1.645 0 Td (. )Tj EMC /Suspect <>BDC 0.243 g 0.0421 Tc -10.721 -1.093 Td (Under )Tj EMC ET BT /T1_0 1 Tf 0.036 Tc 10.1 0 0 10.1 355.0994 710.1707 Tm (ambient )Tj 0.0308 Tc 3.992 0 Td (conditions )Tj 0.0328 Tc 5.093 0 Td (the )Tj 0.0238 Tc 1.937 0 Td (subject )Tj 0.0329 Tc 3.627 0 Td (breathed )Tj 0.0113 Tc -18.927 -1.046 Td (from )Tj 0.009 Tc 2.575 0 Td (the )Tj 0.0282 Tc 1.75 0 Td (atmosphere )Tj -0.0005 Tc 5.372 0 Td (in )Tj 0.0328 Tc 1.337 0 Td (the )Tj 0.0279 Tc 1.807 0 Td (room. )Tj 0.05 Tc 10.2656 0 0 10.1 472.23 699.61 Tm (The )Tj 10.1176 0 0 10.1 494.42 699.61 Tm (probe )Tj -0.0144 Tc 10.1 0 0 10.1 524.63 699.61 Tm (was )Tj 0.0123 Tc -21.06 -1.094 Td (inserted )Tj 0.0365 Tc 3.903 0 Td (through )Tj 0.0328 Tc 3.945 0 Td (the )Tj 0.05 Tc 10.1253 0 0 10.1 410.38 688.56 Tm (mouth )Tj 10.4772 0 0 10.1 444.45 688.56 Tm (to )Tj 0.0328 Tc 10.1 0 0 10.1 459.82 688.56 Tm (the )Tj 0.0271 Tc 1.952 0 Td (pharynx. )Tj 0.184 g 0.0396 Tc 4.361 0 Td (The )Tj 0.243 g 0.0246 Tc -20.951 -1.092 Td (thermistor )Tj 0.05 Tc 10.7518 0 0 10.1 358.93 677.53 Tm (at )Tj 0.0328 Tc 10.1 0 0 10.1 370.54 677.53 Tm (the )Tj 0.0445 Tc 1.568 0 Td (tip )Tj 0.05 Tc 10.5727 0 0 10.1 401.18 677.53 Tm (of )Tj 0.0118 Tc 10.1 0 0 10.1 412.72 677.53 Tm (its )Tj 0.022 Tc 1.293 0 Td (protective )Tj 0.0307 Tc 4.503 0 Td (cage )Tj -0.0144 Tc 2.243 0 Td (was )Tj 0.0034 Tc 1.904 0 Td (placed )Tj 0.0294 Tc -19.972 -1.046 Td (against )Tj -0.0148 Tc 3.382 0 Td (the )Tj 0.0162 Tc 1.568 0 Td (mucosal )Tj 0.0226 Tc 3.743 0 Td (surface )Tj 0.05 Tc 10.7518 0 0 10.1 432.85 666.97 Tm (at )Tj 0.009 Tc 10.1 0 0 10.1 444.94 666.97 Tm (the )Tj 0.0399 Tc 1.619 0 Td (back )Tj 0.05 Tc 11.1292 0 0 10.1 485.17 666.97 Tm (of )Tj 0.322 g 0.0328 Tc 10.1 0 0 10.1 497.26 666.97 Tm (the )Tj 0.243 g 0.05 Tc 10.2419 0 0 10.1 513.57 666.97 Tm (throat )Tj 0.0333 Tc 10.1 0 0 10.1 311.98 655.92 Tm (to )Tj 0.0164 Tc 1.378 0 Td (measure )Tj -0.0012 Tc 3.993 0 Td (wall )Tj 0.0235 Tc 2.28 0 Td (temperature. )Tj 0.184 g 0.05 Tc 10.2805 0 0 10.1 449.23 655.92 Tm (Most )Tj 0.243 g 0.0191 Tc 10.1 0 0 10.1 476.98 655.92 Tm (subjects )Tj 0.0203 Tc 3.901 0 Td (could )Tj 0.0209 Tc -20.297 -1.046 Td (suppress )Tj 0.322 g 0.0302 Tc 3.861 0 Td (their )Tj 0.243 g 0.0225 Tc 2.179 0 Td (gag )Tj -0.0095 Tc 1.719 0 Td (reflex )Tj 0.0252 Tc 2.556 0 Td (for )Tj 0 Tc 1.522 0 Td (a )Tj 0.0009 Tc 0.709 0 Td (sufficient )Tj 0.0114 Tc 4.099 0 Td (time )Tj 0.0333 Tc 2.139 0 Td (to )Tj 0.0317 Tc 1.097 0 Td (permit )Tj 0.021 Tc -19.869 -1.092 Td (measurements )Tj 0.05 Tc 10.7518 0 0 10.1 375.25 634.33 Tm (at )Tj 0.0109 Tc 10.1 0 0 10.1 387.34 634.33 Tm (this )Tj 0.026 Tc 1.847 0 Td (location. )Tj 0.0462 Tc 4.04 0 Td (Then, )Tj 0.0341 Tc 2.85 0 Td (either )Tj 0.0328 Tc 2.86 0 Td (the )Tj 0.0083 Tc 1.664 0 Td (nose )Tj 0.0094 Tc -20.768 -1.093 Td (was )Tj 0.0162 Tc 1.998 0 Td (blocked, )Tj 0.0171 Tc 3.944 0 Td (using )Tj 0.0075 Tc 2.613 0 Td (nose-clips, )Tj 0.0444 Tc 4.791 0 Td (and )Tj 0.05 Tc 10.2999 0 0 10.1 466.54 623.29 Tm (mouth )Tj 0.0345 Tc 10.1 0 0 10.1 499.21 623.29 Tm (breathing )Tj 0.014 Tc -18.594 -1.094 Td (ensued, )Tj 0.05 Tc 10.5727 0 0 10.1 346.46 612.24 Tm (or )Tj 0.0328 Tc 10.1 0 0 10.1 359.5 612.24 Tm (the )Tj 0.0398 Tc 1.616 0 Td (mouth )Tj 0.0331 Tc 3.09 0 Td (was )Tj 0.0164 Tc 1.892 0 Td (closed )Tj 0.05 Tc 10.3398 0 0 10.1 456.37 612.24 Tm (and )Tj 0.184 g 0.0241 Tc 10.1 0 0 10.1 476.15 612.24 Tm (nose )Tj 0.243 g 0.0345 Tc 2.283 0 Td (breathing )Tj 0.0216 Tc -18.593 -1.046 Td (occurred. )Tj 0.05 Tc 10.2656 0 0 10.1 353.19 601.68 Tm (The )Tj 0.0238 Tc 10.1 0 0 10.1 372.34 601.68 Tm (subject )Tj -0.0144 Tc 3.197 0 Td (was )Tj 0.184 g 0.0288 Tc 1.799 0 Td (instructed )Tj 0.243 g 0.05 Tc 10.4772 0 0 10.1 467.97 601.68 Tm (to )Tj 0.0383 Tc 10.1 0 0 10.1 479.42 601.68 Tm (adjust )Tj 0.0328 Tc 2.859 0 Td (the )Tj 0.04 Tc 1.522 0 Td (rate )Tj 0.0444 Tc -21.015 -1.092 Td (and )Tj 0.0294 Tc 1.853 0 Td (depth )Tj 0.05 Tc 11.1292 0 0 10.1 357.49 590.65 Tm (of )Tj 0.0286 Tc 10.1 0 0 10.1 369.61 590.65 Tm (breathing )Tj 0.0333 Tc 4.322 0 Td (to )Tj 0.0432 Tc 1.145 0 Td (produce )Tj 0.0491 Tc 3.743 0 Td (one )Tj 0.05 Tc 11.1292 0 0 10.1 481.33 590.65 Tm (of )Tj 0.0328 Tc 10.1 0 0 10.1 493.9 590.65 Tm (the )Tj 0.0118 Tc 1.56 0 Td (desired )Tj 0.0321 Tc -19.616 -1.093 Td (patterns, )Tj /T1_3 1 Tf 0 Tc 3.977 0 Td (i)Tj 0.086 g 0.336 0 Td (.)Tj 0.243 g 0.0105 Tc 0.191 0 Td (e., )Tj /T1_0 1 Tf 0.0184 Tc 1.282 0 Td (quiet, )Tj 0.0199 Tc 2.708 0 Td (fast )Tj 0.05 Tc 10.5727 0 0 10.1 416.06 579.61 Tm (or )Tj -0.0054 Tc 10.1 0 0 10.1 428.5 579.61 Tm (slow. )Tj 0.184 g 0.05 Tc 10.2656 0 0 10.1 453.51 579.61 Tm (The )Tj 0.243 g 10.1176 0 0 10.1 473.78 579.61 Tm (probe )Tj 0.0094 Tc 10.1 0 0 10.1 502.07 579.61 Tm (was )Tj 0.0136 Tc 1.948 0 Td (then )Tj 0.0247 Tc -20.815 -1.046 Td (withdrawn )Tj 0.0113 Tc 4.838 0 Td (from )Tj 0.0328 Tc 2.385 0 Td (the )Tj 0.05 Tc 10.1253 0 0 10.1 400.78 569.05 Tm (mouth )Tj 0.0444 Tc 10.1 0 0 10.1 432.38 569.05 Tm (and )Tj 0.0224 Tc 1.913 0 Td (placed )Tj 0.05 Tc 11.3843 0 0 10.1 482.76 569.05 Tm (at )Tj 0.0328 Tc 10.1 0 0 10.1 494.86 569.05 Tm (the )Tj 0.0194 Tc 1.608 0 Td (airway )Tj 0.0164 Tc -19.77 -1.094 Td (opening, )Tj 0.0246 Tc 3.896 0 Td (either )Tj 0.05 Tc 10.7518 0 0 10.1 377.65 558 Tm (at )Tj 0.0328 Tc 10.1 0 0 10.1 388.78 558 Tm (the )Tj -0.0165 Tc 1.609 0 Td (lips )Tj 0.05 Tc 10.5727 0 0 10.1 422.3 558 Tm (or )Tj 0.0233 Tc 10.1 0 0 10.1 434.39 558 Tm (nares, )Tj 0.0431 Tc 2.804 0 Td (with )Tj 0.0328 Tc 2.185 0 Td (the )Tj 0.0445 Tc 1.568 0 Td (tip )Tj 0.05 Tc 11.6856 0 0 10.1 514.93 558 Tm (of )Tj 0.0328 Tc 10.1 0 0 10.1 527.02 558 Tm (the )Tj 0.0148 Tc -21.394 -1.092 Td (cage )Tj 0.0235 Tc 2.289 0 Td (touching )Tj 0.184 g 0.009 Tc 4.087 0 Td (the )Tj 0.243 g 0.05 Tc 10.1123 0 0 10.1 391.66 546.97 Tm (most )Tj 0.0291 Tc 10.1 0 0 10.1 416.66 546.97 Tm (proximal )Tj 0.0057 Tc 4.218 0 Td (accessible )Tj 0.032 Tc 4.475 0 Td (mucosal )Tj 0.004 Tc -19.117 -1.094 Td (surface. )Tj 0.184 g 0.05 Tc 10.2656 0 0 10.1 346.95 535.92 Tm (The )Tj 0.243 g 0.0214 Tc 10.1 0 0 10.1 367.06 535.92 Tm (same )Tj 0.0345 Tc 2.486 0 Td (breathing )Tj 0.0452 Tc 4.373 0 Td (patterns )Tj 0.004 Tc 3.847 0 Td (were )Tj 0.0272 Tc 2.281 0 Td (repeated. )Tj 0.184 g 0.012 Tc -17.541 -1.046 Td (Before )Tj 0.243 g 0.05 Tc 10.3398 0 0 10.1 352.69 525.36 Tm (and )Tj 0.0406 Tc 10.1 0 0 10.1 372.38 525.36 Tm (during )Tj 0.0328 Tc 3.192 0 Td (the )Tj 0.0312 Tc 1.62 0 Td (positioning )Tj 0.05 Tc 11.6856 0 0 10.1 473.17 525.36 Tm (of )Tj 0.0328 Tc 10.1 0 0 10.1 486.22 525.36 Tm (the )Tj 0.05 Tc 10.1176 0 0 10.1 503.06 525.36 Tm (probe )Tj 10.1194 0 0 10.1 531.74 525.36 Tm (at )Tj 0.0328 Tc 10.1 0 0 10.1 311.5 514.33 Tm (the )Tj 0.0194 Tc 1.75 0 Td (airway )Tj 0.0291 Tc 3.327 0 Td (opening )Tj 0.05 Tc 10.5727 0 0 10.1 402.14 514.33 Tm (or )Tj -0.0005 Tc 10.1 0 0 10.1 416.56 514.33 Tm (in )Tj 0.184 g 0.0328 Tc 1.337 0 Td (the )Tj 0.243 g 0.0339 Tc 1.81 0 Td (pharynx, )Tj 0.322 g 0.0328 Tc 4.321 0 Td (the )Tj 0.243 g 0.0159 Tc 1.794 0 Td (subject )Tj 0.0329 Tc -19.66 -1.094 Td (breathed )Tj 0.036 Tc 4.076 0 Td (ambient )Tj 0.0493 Tc 3.85 0 Td (air)Tj 0.086 g 0 Tc 1.177 0 Td (. )Tj 0.243 g 0.0354 Tc 0.637 0 Td (As )Tj 0.0441 Tc 1.604 0 Td (soon )Tj 0.05 Tc 10.4714 0 0 10.1 450.61 503.28 Tm (as )Tj 0.0328 Tc 10.1 0 0 10.1 464.62 503.28 Tm (the )Tj 0.05 Tc 10.1176 0 0 10.1 481.94 503.28 Tm (probe )Tj 0.0094 Tc 10.1 0 0 10.1 511.19 503.28 Tm (was )Tj -0.035 Tc 9.9195 0 0 10.1 531.76 503.28 Tm (in )Tj 0.184 g 0.0189 Tc 10.1 0 0 10.1 311.54 492.72 Tm (position, )Tj 0.243 g 0.0328 Tc 4.178 0 Td (the )Tj 0.0159 Tc 1.842 0 Td (subject )Tj 0.0437 Tc 3.422 0 Td (started )Tj 0.05 Tc 10.4772 0 0 10.1 442.05 492.72 Tm (to )Tj 0.0425 Tc 10.1 0 0 10.1 456.49 492.72 Tm (breathe )Tj 0.184 g 0.0328 Tc 3.751 0 Td (the )Tj 0.243 g 0.0162 Tc 1.798 0 Td (condi\255)Tj 0.0238 Tc -19.905 -1.092 Td (tioned )Tj 0.0493 Tc 2.844 0 Td (air )Tj 0.05 Tc 10.7518 0 0 10.1 354.13 481.69 Tm (at )Tj 0 Tc 10.1 0 0 10.1 364.7 481.69 Tm (a )Tj -0.0048 Tc 0.761 0 Td (given )Tj 0.0269 Tc 2.479 0 Td (rate, )Tj /T1_3 1 Tf -0.0085 Tc 2.181 0 Td (viz., )Tj /T1_0 1 Tf 0.0338 Tc 1.858 0 Td (normal, )Tj 0.0127 Tc 3.551 0 Td (slow )Tj 0.05 Tc 10.5727 0 0 10.1 496.22 481.69 Tm (or )Tj 0.0118 Tc 10.1 0 0 10.1 508.21 481.69 Tm (fast. )Tj 0.05 Tc 10.1228 0 0 10.1 528.94 481.69 Tm (At )Tj 0.0444 Tc 10.1 0 0 10.1 310.94 470.65 Tm (any )Tj 0.0253 Tc 1.901 0 Td (one )Tj 0.05 Tc 11.1292 0 0 10.1 348.85 470.65 Tm (of )Tj 0.0104 Tc 10.1 0 0 10.1 361.42 470.65 Tm (these )Tj 0.0198 Tc 2.472 0 Td (rates, )Tj 0.05 Tc 10.7542 0 0 10.1 412.69 470.65 Tm (an )Tj 10.1643 0 0 10.1 427.1 470.65 Tm (apparent )Tj 0.0364 Tc 10.1 0 0 10.1 468.82 470.65 Tm (steady )Tj 0.0362 Tc 3.089 0 Td (state )Tj 0.0094 Tc 2.342 0 Td (was )Tj 0.0132 Tc -21.006 -1.046 Td (reached )Tj 0.0445 Tc 3.508 0 Td (after )Tj 0 Tc 2.281 0 Td (a )Tj -0.035 Tc 9.9503 0 0 10.1 378.13 460.09 Tm (few )Tj 0.0356 Tc 10.1 0 0 10.1 396.49 460.09 Tm (breaths )Tj 0.184 g 0.0345 Tc 3.411 0 Td (as )Tj 0.086 g 0 Tc 1.19 0 Td (i)Tj 0.184 g 0.0264 Tc 0.292 0 Td (ndicated )Tj 0.243 g 0.0076 Tc 3.947 0 Td (by )Tj 0.0328 Tc 1.375 0 Td (the )Tj 0.0288 Tc 1.617 0 Td (water )Tj 0.0447 Tc -20.294 -1.093 Td (vapour )Tj 0.0444 Tc 3.366 0 Td (and )Tj 0.0318 Tc 2.004 0 Td (temperature )Tj 0.322 g 0.0137 Tc 5.453 0 Td (signa)Tj 0.184 g 0 Tc 2.191 0 Td (l)Tj 0.322 g 0.0041 Tc 0.233 0 Td (s. )Tj 0.184 g 0.0371 Tc 1.1 0 Td (In )Tj 0.243 g 0.0328 Tc 1.288 0 Td (the )Tj 0.0269 Tc 1.699 0 Td (steady )Tj 0.0265 Tc 3.042 0 Td (state, )Tj 0.184 g 0.05 Tc 10.377 0 0 10.1 310.94 438 Tm (data )Tj 0.243 g 0.004 Tc 10.1 0 0 10.1 335.03 438 Tm (were )Tj 0.0301 Tc 2.518 0 Td (taken )Tj 0.0015 Tc 2.843 0 Td (for )Tj 0.184 g -0.035 Tc 9.6688 0 0 10.1 407.67 438 Tm (15 )Tj 0.243 g 0.05 Tc 10.4772 0 0 10.1 422.37 438 Tm (to )Tj -0.035 Tc 9.8266 0 0 10.1 436.69 438 Tm (30 )Tj 9.9525 0 0 10.1 451.54 438 Tm (s. )Tj 0.184 g 0.034 Tc 10.1 0 0 10.1 463.59 438 Tm (Then )Tj 0.0328 Tc 2.763 0 Td (the )Tj 0.243 g 0.0159 Tc 1.794 0 Td (subject )Tj 0.0329 Tc -19.66 -1.092 Td (breathed )Tj 0.05 Tc 10.7518 0 0 10.1 350.77 426.97 Tm (at )Tj 0.049 Tc 10.1 0 0 10.1 361.82 426.97 Tm (another )Tj -0.0309 Tc 3.563 0 Td (fixed )Tj 0.184 g 0.0242 Tc 2.291 0 Td (rate )Tj 0.243 g 0.0295 Tc 1.854 0 Td (until )Tj 0 Tc 2.224 0 Td (a )Tj 0.0246 Tc 0.769 0 Td (new )Tj 0.0174 Tc 1.983 0 Td (steady )Tj 0.322 g 0.0362 Tc 2.947 0 Td (state )Tj 0.243 g 0.0094 Tc -20.66 -1.093 Td (was )Tj 0.0077 Tc 1.892 0 Td (achieved. )Tj 0.014 Tc 4.285 0 Td (Again, )Tj 0.05 Tc 10.377 0 0 10.1 405.02 415.93 Tm (data )Tj 0.004 Tc 10.1 0 0 10.1 427.19 415.93 Tm (were )Tj 0.0301 Tc 2.328 0 Td (taken )Tj 0.0252 Tc 2.7 0 Td (for )Tj -0.035 Tc 9.1317 0 0 10.1 495.04 415.93 Tm (15 )Tj 0.05 Tc 10.4772 0 0 10.1 507.33 415.93 Tm (to )Tj -0.0126 Tc 10.1 0 0 10.1 519.72 415.93 Tm (30 )Tj -0.035 Tc 9.9525 0 0 10.1 533.14 415.93 Tm (s. )Tj 0.0313 Tc 10.1 0 0 10.1 310.47 404.89 Tm (This )Tj 0.0169 Tc 2.53 0 Td (process )Tj 0.0094 Tc 3.751 0 Td (was )Tj 0.0193 Tc 2.234 0 Td (repeated )Tj 0.0252 Tc 4.22 0 Td (for )Tj 0.0328 Tc 1.957 0 Td (the )Tj 0.0397 Tc 1.949 0 Td (third )Tj 0.0114 Tc 2.756 0 Td (time )Tj 0.05 Tc 10.7518 0 0 10.1 531.25 404.89 Tm (at )Tj 0.0411 Tc 10.1 0 0 10.1 310.94 394.33 Tm (another )Tj 0.0286 Tc 3.623 0 Td (breathing )Tj 0.184 g 0.0151 Tc 4.37 0 Td (rate. )Tj 0.243 g 0.05 Tc 11.0881 0 0 10.1 320.59 383.28 Tm (For )Tj 0.0328 Tc 10.1 0 0 10.1 341.74 383.28 Tm (the )Tj 0.0124 Tc 1.794 0 Td (subjects )Tj 0.0333 Tc 3.814 0 Td (to )Tj 0.019 Tc 1.325 0 Td (inhale )Tj 0.0305 Tc 3.041 0 Td (gas )Tj 0.05 Tc 10.6555 0 0 10.1 461.19 383.28 Tm (in )Tj 0 Tc 10.1 0 0 10.1 474.62 383.28 Tm (a )Tj 0.184 g 0.05 Tc 10.2211 0 0 10.1 484.79 383.28 Tm (non)Tj 0.322 g 10.3131 0 0 10.1 501 383.28 Tm (-am)Tj 0.184 g 0.014 Tc 10.1 0 0 10.1 518.41 383.28 Tm (bient )Tj 0.243 g 0.0304 Tc -20.589 -1.092 Td (condition, )Tj 0.0294 Tc 4.57 0 Td (they )Tj 0.004 Tc 2.092 0 Td (were )Tj -0.007 Tc 2.224 0 Td (fitted )Tj -0.0044 Tc 2.481 0 Td (with )Tj 0 Tc 2.082 0 Td (a )Tj 0.184 g 0.0149 Tc 0.768 0 Td (modified )Tj 0.243 g 0 Tc 3.984 0 Td (d)Tj 0.086 g 0.572 0 Td (i)Tj 0.243 g 0.0212 Tc 0.279 0 Td (sposable )Tj 0.0048 Tc -19.006 -1.093 Td (oxygen )Tj 0.0114 Tc 3.335 0 Td (mask )Tj 0.0176 Tc 2.52 0 Td (having )Tj 0 Tc 3.128 0 Td (a )Tj 0.0187 Tc 0.82 0 Td (plastic )Tj 0.0444 Tc 3.039 0 Td (hood. )Tj 0 Tc 2.803 0 Td (A )Tj 0.322 g -0.0172 Tc 1.034 0 Td (suffici)Tj 0.184 g 0.05 Tc 10.3365 0 0 10.1 504.37 361.21 Tm (ent )Tj -0.0151 Tc 10.1 0 0 10.1 520.69 361.21 Tm (flow )Tj 0.243 g 0.05 Tc 11.1292 0 0 10.1 310.93 350.16 Tm (of )Tj 0.0305 Tc 10.1 0 0 10.1 326.79 350.16 Tm (gas )Tj -0.0144 Tc 2.147 0 Td (was )Tj 0.0223 Tc 2.268 0 Td (supplied )Tj 0.05 Tc 10.4772 0 0 10.1 415.17 350.16 Tm (to )Tj 0.009 Tc 10.1 0 0 10.1 431.98 350.16 Tm (the )Tj 0.0272 Tc 2.044 0 Td (mask )Tj 0.184 g 0.05 Tc 10.4772 0 0 10.1 482.85 350.16 Tm (to )Tj 0.243 g 0.0241 Tc 10.1 0 0 10.1 499.09 350.16 Tm (ensure )Tj 0 Tc 3.47 0 Td (a )Tj 0.0324 Tc -22.147 -1.045 Td (continuous )Tj 0.0396 Tc 5.094 0 Td (washout )Tj 0.05 Tc 11.1292 0 0 10.1 402.13 339.61 Tm (of )Tj 0.006 Tc 10.1 0 0 10.1 415.1 339.61 Tm (all )Tj 0.0188 Tc 1.425 0 Td (expired )Tj 0.0162 Tc 3.519 0 Td (gas. )Tj 0.184 g 0.05 Tc 10.5804 0 0 10.1 486.19 339.61 Tm (Hot )Tj 0.243 g 0.0493 Tc 10.1 0 0 10.1 507.26 339.61 Tm (air )Tj 0.0094 Tc 1.577 0 Td (was )Tj 0.184 g 0.0267 Tc -21.003 -1.094 Td (produced )Tj 0.243 g 0.0052 Tc 4.465 0 Td (using )Tj 0 Tc 2.699 0 Td (a )Tj 0.046 Tc 0.95 0 Td (common )Tj 0.0252 Tc 4.286 0 Td (hairdryer. )Tj 0.05 Tc 10.5434 0 0 10.1 483.73 328.56 Tm (Gas )Tj 0.0134 Tc 10.1 0 0 10.1 506.86 328.56 Tm (temper\255)Tj 0.05 Tc 10.1056 0 0 10.1 310.46 317.53 Tm (ature )Tj 0.184 g -0.0005 Tc 10.1 0 0 10.1 337.84 317.53 Tm (in )Tj 0.243 g 0.009 Tc 1.384 0 Td (the )Tj 0.0114 Tc 1.806 0 Td (mask )Tj 0.0331 Tc 2.71 0 Td (was )Tj 0.0337 Tc 2.138 0 Td (monitored )Tj 0.0273 Tc 4.944 0 Td (with )Tj 0.05 Tc 11.243 0 0 10.1 492.84 317.53 Tm (an )Tj 0.0111 Tc 10.1 0 0 10.1 508.69 317.53 Tm (electric )Tj 0.0216 Tc -19.571 -1.093 Td (telethermometer )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.016 Tc 10.1 0 0 10.1 383.8843 306.4907 Tm (\(Omega )Tj EMC ET BT 0.184 g /T1_0 1 Tf 0.0104 Tc 10.1 0 0 10.1 421.3856 306.4907 Tm (Eng., )Tj 0.243 g 0.0395 Tc 2.52 0 Td (Model )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0155 Tc 10.1 0 0 10.1 478.4304 306.4907 Tm (5800\). )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 10.2656 0 0 10.1 320.07 295.44 Tm (The )Tj 0.0049 Tc 10.1 0 0 10.1 341.17 295.44 Tm (following )Tj 0.0194 Tc 4.334 0 Td (variables )Tj 0.004 Tc 4.183 0 Td (were )Tj 0.184 g 0.0303 Tc 2.329 0 Td (recorded )Tj 0.243 g 0.05 Tc 10.2564 0 0 10.1 492.38 295.44 Tm (on )Tj 0 Tc 10.1 0 0 10.1 507.74 295.44 Tm (a )Tj 0.0205 Tc 0.851 0 Td (strip\255)Tj 0.0407 Tc -20.384 -1.045 Td (chart )Tj 0.027 Tc 2.718 0 Td (recorder )Tj 0.0228 Tc 4.029 0 Td (\(Brush, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0223 Tc 10.1 0 0 10.1 415.5472 284.8855 Tm (660\): )Tj EMC ET BT 0.184 g /T1_0 1 Tf 0.0241 Tc 10.1 0 0 10.1 442.0597 284.8855 Tm (mucosal )Tj 0.243 g -0.0012 Tc 4.041 0 Td (wall )Tj 0.0134 Tc 2.328 0 Td (temper\255)Tj 0.0384 Tc -19.398 -1.094 Td (ature )Tj 0.013 Tc 2.422 0 Td (\(Tw\), )Tj 0.0305 Tc 2.569 0 Td (gas )Tj 0.0366 Tc 1.67 0 Td (temperature )Tj 0.0204 Tc 5.36 0 Td (\(T\), )Tj 0.0288 Tc 1.912 0 Td (water )Tj 0.05 Tc 10.1706 0 0 10.1 477.58 273.84 Tm (vapour )Tj 0.028 Tc 10.1 0 0 10.1 511.22 273.84 Tm (partial )Tj 0.0212 Tc -19.865 -1.092 Td (pressure )Tj -0.035 Tc 9.776 0 0 10.1 349.32 262.81 Tm (\(PH)Tj 0 Tc 6.5001 0 0 6.5001 364.76 260.41 Tm (2)Tj 0.05 Tc 9.9191 0 0 9.5 368.54 262.81 Tm (0\), )Tj 0.184 g 0.04 Tc 10.1 0 0 10.1 383.99 262.81 Tm (rate )Tj 0.243 g 0.05 Tc 11.1292 0 0 10.1 404.05 262.81 Tm (of )Tj 0.0275 Tc 10.1 0 0 10.1 416.54 262.81 Tm (change )Tj 0.05 Tc 11.1292 0 0 10.1 450.13 262.81 Tm (of )Tj 0.184 g 0.0306 Tc 10.1 0 0 10.1 462.63 262.81 Tm (lung )Tj 0.243 g 0.0195 Tc 2.241 0 Td (volume )Tj ET BT /Suspect <>BDC /T1_2 1 Tf 0.0412 Tc 9.2 0 0 9.2 520.16 262.81 Tm (\(VL\) )Tj EMC ET BT /T1_0 1 Tf 0.0444 Tc 10.1 0 0 10.1 310.46 251.76 Tm (and )Tj 0.028 Tc 1.913 0 Td (partial )Tj 0.0212 Tc 3.089 0 Td (pressure )Tj 0.05 Tc 11.1292 0 0 10.1 399.25 251.76 Tm (of )Tj 0.184 g 0.0495 Tc 10.1 0 0 10.1 411.26 251.76 Tm (carbon )Tj 0.0248 Tc 3.279 0 Td (dioxide )Tj ET BT /Suspect <>BDC 0.243 g /T1_0 1 Tf 0.05 Tc 10.514 0 0 10.1 479.4 251.76 Tm (\(Pco)Tj /T1_2 1 Tf 0 Tc 6.2 0 0 6.2 500.11 249.37 Tm (2)Tj 0.05 Tc 8.369 0 0 6.2 504.33 251.76 Tm (\). )Tj EMC ET BT /T1_0 1 Tf 0.0354 Tc 10.1 0 0 10.1 513.58 251.76 Tm (As )Tj 0.05 Tc 10.2654 0 0 10.1 528.38 251.76 Tm (an )Tj 0.0227 Tc 10.1 0 0 10.1 310.48 241.21 Tm (indication )Tj 0.05 Tc 11.6856 0 0 10.1 358.45 241.21 Tm (of )Tj 0.0177 Tc 10.1 0 0 10.1 373.45 241.21 Tm (body )Tj 0.0357 Tc 2.603 0 Td (core )Tj 0.0321 Tc 2.384 0 Td (temperature, )Tj 0.0328 Tc 5.988 0 Td (the )Tj 0.024 Tc 1.794 0 Td (subject's )Tj 0.0208 Tc -19.01 -1.094 Td (sublingual )Tj 0.0318 Tc 4.907 0 Td (temperature )Tj -0.0144 Tc 5.704 0 Td (was )Tj 0.0301 Tc 2.138 0 Td (taken )Tj 0.0273 Tc 2.9 0 Td (with )Tj 0 Tc 2.415 0 Td (a )Tj 0.0241 Tc 1.053 0 Td (mercury )Tj 0.0317 Tc -19.105 -1.092 Td (thermometer )Tj 0.05 Tc 10.7518 0 0 10.1 373.33 219.13 Tm (at )Tj 0.0328 Tc 10.1 0 0 10.1 389.74 219.13 Tm (the )Tj 0.0184 Tc 2.142 0 Td (beginning )Tj 0.0444 Tc 4.932 0 Td (and )Tj 0.025 Tc 2.375 0 Td (end )Tj 0.05 Tc 11.1292 0 0 10.1 508.69 219.13 Tm (of )Tj 0.009 Tc 10.1 0 0 10.1 526.06 219.13 Tm (the )Tj 0.0172 Tc -21.395 -1.093 Td (experiment. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0221 Tc 10.1 0 0 10.1 362.8743 208.0907 Tm (Using )Tj EMC ET BT /T1_0 1 Tf 0.0328 Tc 10.1 0 0 10.1 390.6998 208.0907 Tm (the )Tj 0.004 Tc 1.616 0 Td (values )Tj 0.05 Tc 11.1292 0 0 10.1 435.73 208.09 Tm (of )Tj 0.0059 Tc 10.1 0 0 10.1 447.27 208.09 Tm (local )Tj 0.0067 Tc 2.281 0 Td (gas )Tj 0.0318 Tc 1.67 0 Td (temperature )Tj 0.05 Tc 10.3398 0 0 10.1 309.97 197.52 Tm (and )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0259 Tc 10.1 0 0 10.1 329.73 197.52 Tm (Water )Tj EMC ET BT /T1_0 1 Tf 0.0447 Tc 10.1 0 0 10.1 357.101 197.52 Tm (vapour )Tj 0.0359 Tc 3.331 0 Td (partial )Tj 0.0212 Tc 3.137 0 Td (pressure )Tj 0.05 Tc 10.7518 0 0 10.1 460.69 197.52 Tm (at )Tj 0.0397 Tc 10.1 0 0 10.1 472.82 197.52 Tm (peak )Tj -0.0254 Tc 2.363 0 Td (flows )Tj -0.0005 Tc 2.522 0 Td (in )Tj 0 Tc 1.139 0 Td (a )Tj 0.0429 Tc -22.136 -1.092 Td (breath, )Tj -0.02 Tc 3.325 0 Td (we )Tj 0.0226 Tc 1.464 0 Td (calculated )Tj 0.009 Tc 4.665 0 Td (the )Tj 0.184 g 0.0059 Tc 1.609 0 Td (local )Tj 0.0138 Tc 2.337 0 Td (relative )Tj 0.243 g 0.0232 Tc 3.469 0 Td (humidity. )Tj /T1_4 1 Tf 0.0185 Tc 9.4 0 0 9.4 408.91 161.52 Tm (Results )Tj 0.322 g /T1_3 1 Tf 0.0017 Tc 10.1 0 0 10.1 310.36 146.65 Tm (Characterization )Tj 0.243 g 0.05 Tc 12.4923 0 0 10.1 383.42 146.65 Tm (of )Tj 0.0109 Tc 10.1 0 0 10.1 395.4 146.65 Tm (the )Tj 0.0042 Tc 1.575 0 Td (data )Tj /T1_0 1 Tf 0.0093 Tc -9.034 -1.474 Td (Typical )Tj 0.0301 Tc 4.039 0 Td (dynamic )Tj 0.0225 Tc 4.524 0 Td (recordings )Tj 0.05 Tc 11.1292 0 0 10.1 460.21 131.76 Tm (of )Tj 0.0328 Tc 10.1 0 0 10.1 478.54 131.76 Tm (the )Tj 0.0194 Tc 2.186 0 Td (variables )Tj 0.0173 Tc -18.867 -1.093 Td (measured )Tj 0.0192 Tc 4.455 0 Td (simultaneously )Tj 0.184 g -0.035 Tc 9.9195 0 0 10.1 423.76 120.72 Tm (in )Tj 0.243 g 0.0328 Tc 10.1 0 0 10.1 436.3 120.72 Tm (the )Tj 0.0322 Tc 1.759 0 Td (nares )Tj -0.0264 Tc 2.65 0 Td (\(fig. )Tj 0 Tc 2.163 0 Td (1 )Tj 0.184 g -0.0036 Tc 0.46 0 Td (A\) )Tj 0.243 g 0.0444 Tc 1.513 0 Td (and )Tj 0.322 g -0.0005 Tc -21.051 -1.046 Td (in )Tj 0.243 g 0.0328 Tc 1.384 0 Td (the )Tj 0.0337 Tc 1.857 0 Td (pharynx )Tj -0.0264 Tc 4.026 0 Td (\(fig. )Tj /T1_5 1 Tf 0 Tc 9.4 0 0 9.4 406.82 110.16 Tm (1 )Tj 0.184 g /T1_0 1 Tf -0.035 Tc 9.6774 0 0 10.1 411.32 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g 0 Tc 0.809 0 Td (r)Tj 0.29 g -0.0067 Tc 0.329 0 Td (way )Tj 0.0158 Tc -20.621 -1.082 Td (opening )Tj 0.0235 Tc 3.82 0 Td (than )Tj 0.044 Tc 2.298 0 Td (at )Tj 0.227 g 0.0029 Tc 1.325 0 Td (the )Tj 0.29 g 0.0219 Tc 1.698 0 Td (pharynx. )Tj 0.0274 Tc 4.184 0 Td (After )Tj 0.0266 Tc 2.675 0 Td (accounting )Tj 0.0192 Tc 5.081 0 Td (for )Tj 0.0055 Tc -21.074 -1.083 Td (time )Tj 0.227 g -0.0004 Tc 2.11 0 Td (delays )Tj 0.29 g 0.0404 Tc 2.871 0 Td (among )Tj -0.0033 Tc 3.196 0 Td (signa)Tj 0.145 g 0 Tc 2.17 0 Td (l)Tj 0.29 g 0.23 0 Td (s)Tj 0.388 0.388 0.384 rg 0.422 0 Td (, )Tj 0.29 g 0.0317 Tc 0.524 0 Td (correspond)Tj 0.145 g 0 Tc 4.755 0 Td (i)Tj 0.29 g -0.0085 Tc 0.289 0 Td (ng )Tj 0.0346 Tc 1.31 0 Td (landmarks )Tj 0.0257 Tc -17.93 -1.081 Td (during )Tj 0 Tc 3.341 0 Td (a )Tj 0.0298 Tc 1.093 0 Td (breath )Tj 0.0229 Tc 3.236 0 Td (can )Tj 0.0069 Tc 2.023 0 Td (easi)Tj 0.145 g 0 Tc 1.602 0 Td (l)Tj 0.29 g 0.243 0 Td (y )Tj -0.035 Tc 10.1515 0 0 10.2 168.01 162.49 Tm (be )Tj 0.0053 Tc 10.2 0 0 10.2 183.28 162.49 Tm (identified )Tj 0.0192 Tc 4.515 0 Td (for )Tj 0.0244 Tc 1.741 0 Td (each )Tj 0.0471 Tc -20.415 -1.035 Td (var)Tj 0.145 g 0 Tc 1.359 0 Td (i)Tj 0.29 g -0.0049 Tc 0.28 0 Td (able. )Tj 0.227 g 0.05 Tc 10.4937 0 0 10.2 77.67 151.93 Tm (Th)Tj 0.388 0.388 0.384 rg 0 Tc 10.2 0 0 10.2 89.65 151.93 Tm [(e )-9(s)]TJ 0.29 g 0.0148 Tc 1.091 0 Td (teady-state )Tj 0.0204 Tc 4.707 0 Td (wave)Tj 0.388 0.388 0.384 rg 0 Tc 2.154 0 Td (-)Tj 0.29 g 0.0275 Tc 0.28 0 Td (shapes )Tj 0.0313 Tc 3.016 0 Td (are )Tj 0.0146 Tc 1.505 0 Td (established )Tj 0.0079 Tc -17.731 -1.082 Td (within )Tj 0.0046 Tc 2.964 0 Td (two )Tj 0.0253 Tc 1.835 0 Td (to )Tj -0.035 Tc 10.1418 0 0 10.2 99.25 140.89 Tm (five )Tj 0.0227 Tc 10.2 0 0 10.2 117.13 140.89 Tm [(breaths )-11(afte)]TJ 0.145 g 0 Tc 4.939 0 Td (r )Tj 0.29 g 0.65 0 Td (a )Tj 0.0217 Tc 0.753 0 Td (change )Tj -0.0079 Tc 3.249 0 Td (in )Tj 0.0237 Tc 1.138 0 Td (breathing )Tj 0.0266 Tc -18.399 -1.082 Td (pattern. )Tj 0.0317 Tc 3.895 0 Td (The )Tj 0.227 g 0 Tc 2.212 0 Td (T )Tj 0.29 g 0.05 Tc 10.3398 0 0 10.2 114.61 129.85 Tm (and )Tj 0.227 g -0.035 Tc 9.3838 0 0 10.2 137.24 129.85 Tm (PH)Tj 0 Tc 6.4001 0 0 6.4001 149.24 127.44 Tm (2)Tj 8.5 0 0 8.5 153.51 129.85 Tm (0 )Tj 0.29 g 0.0045 Tc 10.2 0 0 10.2 165.46 129.85 Tm (signals )Tj 0.0334 Tc 3.495 0 Td (had )Tj 0.227 g 0.0084 Tc 2.156 0 Td (distinctive )Tj 0.0159 Tc -18.062 -1.083 Td (reproducible )Tj 0.29 g 0.0171 Tc 5.591 0 Td (characteristics )Tj 0.05 Tc 10.2564 0 0 10.2 160.7 118.8 Tm (on )Tj 0.0214 Tc 10.2 0 0 10.2 175.6 118.8 Tm (inspiration )Tj 0.037 Tc 4.939 0 Td (and )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0024 Tc 10.2 0 0 10.2 245.6434 118.8 Tm (expi\255)Tj EMC ET BT 0.227 g /T1_0 1 Tf 0.0329 Tc 10.2 0 0 10.2 38.8588 108.2532 Tm (ration)Tj 0.388 0.388 0.384 rg 0 Tc 2.569 0 Td (. )Tj 0.29 g 0.05 Tc 10.2656 0 0 10.2 69.99 108.25 Tm (The )Tj 0.0029 Tc 10.2 0 0 10.2 90.23 108.25 Tm (wave-shapes )Tj 0 Tc 5.497 0 Td (a)Tj 0.145 g 0.526 0 Td (r)Tj 0.29 g 0.32 0 Td (e )Tj 0.0205 Tc 0.797 0 Td (similar )Tj 0.227 g 0.0102 Tc 3.213 0 Td (regardless )Tj 0.05 Tc 11.1292 0 0 10.2 241.33 108.25 Tm (of )Tj 0.29 g 0.0029 Tc 10.2 0 0 10.2 253.9 108.25 Tm (the )Tj 0.013 Tc -21.135 -1.083 Td (inspired )Tj 0.0437 Tc 3.622 0 Td (air )Tj 0.0257 Tc 1.412 0 Td (condition, )Tj 0.0256 Tc 4.576 0 Td (pathway )Tj 0.0107 Tc 3.902 0 Td (travelled )Tj 0.05 Tc 10.5727 0 0 10.2 215.9 97.2 Tm (or )Tj 0.0155 Tc 10.2 0 0 10.2 227.98 97.2 Tm (measure\255)Tj 0.026 Tc -18.541 -1.082 Td (ment )Tj 0.227 g 0.0097 Tc 2.44 0 Td (location. )Tj 0.0168 Tc 3.999 0 Td (Given )Tj 0.29 g 0.0029 Tc 2.925 0 Td (the )Tj 0.227 g 0.0163 Tc 1.648 0 Td (reproducibility )Tj 0.29 g 0.05 Tc 11.1292 0 0 10.2 218.29 86.16 Tm (of )Tj 10.2 0 0 10.2 230.86 86.16 Tm (the )Tj 0.227 g 0.0447 Tc 1.639 0 Td (data )Tj 0.29 g 0.0192 Tc -20.472 -1.082 Td (for )Tj 0.0087 Tc 1.553 0 Td (each )Tj 0.0237 Tc 2.271 0 Td (breathing )Tj 0.227 g 0.04 Tc 4.283 0 Td (pattern, )Tj 0.29 g -0.0311 Tc 3.668 0 Td (we )Tj 0.0245 Tc 1.45 0 Td (chose )Tj 0.05 Tc 10.4772 0 0 10.2 201.57 75.12 Tm (to )Tj 0.0232 Tc 10.2 0 0 10.2 213.98 75.12 Tm (quantify )Tj 0.0029 Tc 3.914 0 Td (the )Tj -0.0267 Tc 3.813 64.236 Td (wave)Tj 0.388 0.388 0.384 rg 0 Tc 2.06 0 Td (-)Tj 0.29 g 0.0087 Tc 0.327 0 Td (shapes )Tj -0.0022 Tc 3.309 0 Td (by )Tj 0.227 g 0.0137 Tc 1.55 0 Td (their )Tj 0.29 g -0.0011 Tc 2.447 0 Td (values )Tj 0.0257 Tc 3.098 0 Td (during )Tj 0.0265 Tc 3.349 0 Td (the )Tj 0.0322 Tc 1.779 0 Td (expiratory )Tj 0 Tc -17.964 -1.036 Td (p)Tj 0.145 g 0.554 0 Td (l)Tj 0.29 g 0.0292 Tc 0.234 0 Td (ateau )Tj 0.037 Tc 2.776 0 Td (and )Tj 0.0265 Tc 2.078 0 Td (the )Tj 0.0141 Tc 1.732 0 Td (extrem)Tj 0.388 0.388 0.384 rg 0 Tc 2.871 0 Td (e )Tj 0.29 g 0.0083 Tc 0.903 0 Td (values )Tj 0.227 g 0.0445 Tc 3.051 0 Td (during )Tj 0.29 g 0.0224 Tc 3.343 0 Td (inspiration. )Tj 0.0317 Tc -17.554 -1.081 Td (The )Tj 0.0332 Tc 2.034 0 Td (peak )Tj -0.035 Tc 10.1707 0 0 10.2 337.81 708.73 Tm (flow )Tj 0.0147 Tc 10.2 0 0 10.2 360.36 708.73 Tm (\(or )Tj 0.227 g 0.0348 Tc 1.658 0 Td (rate )Tj 0.29 g 0.05 Tc 11.1292 0 0 10.2 397.81 708.73 Tm (of )Tj 0.227 g 0.0088 Tc 10.2 0 0 10.2 411.27 708.73 Tm (lung )Tj 0.29 g 0.0135 Tc 2.219 0 Td (volume )Tj 0.0175 Tc 3.522 0 Td (change\) )Tj 0.0192 Tc 3.717 0 Td (for )Tj 0.0087 Tc -21.129 -1.083 Td (each )Tj 0.0335 Tc 2.46 0 Td (phase )Tj 0.05 Tc 11.1292 0 0 10.2 347.89 697.68 Tm (of )Tj 0.0029 Tc 10.2 0 0 10.2 362.86 697.68 Tm (the )Tj 0.227 g 0.0298 Tc 1.885 0 Td (breath )Tj 0.29 g -0.0218 Tc 3.245 0 Td (was )Tj 0.227 g 0.0013 Tc 2.166 0 Td (used )Tj 0.29 g 0.0261 Tc 2.484 0 Td (as )Tj 0 Tc 1.459 0 Td (a )Tj 0.227 g 0.0094 Tc 1.138 0 Td (relative )Tj 0.29 g 0.0108 Tc -19.248 -1.035 Td (measure )Tj 0.05 Tc 10.5727 0 0 10.2 333.98 687.12 Tm (of )Tj 0.0202 Tc 10.2 0 0 10.2 348.86 687.12 Tm (air )Tj 0.227 g -0.021 Tc 1.693 0 Td (flow )Tj 0.29 g 0.0192 Tc 2.447 0 Td (for )Tj 0.028 Tc 1.836 0 Td (comparison )Tj 0.05 Tc 11.6856 0 0 10.2 466.45 687.12 Tm (of )Tj 10.5072 0 0 10.2 481.9 687.12 Tm (var)Tj 0.145 g 0 Tc 10.2 0 0 10.2 496.24 687.12 Tm (i)Tj 0.29 g 0.0074 Tc 0.28 0 Td (ables )Tj 0.0286 Tc -20.282 -1.081 Td (among )Tj 0.0237 Tc 3.211 0 Td (breathing )Tj 0.0217 Tc 4.33 0 Td (patterns. )Tj 0.05 Tc 10.2656 0 0 10.2 301.83 665.53 Tm (The )Tj 0.0464 Tc 10.2 0 0 10.2 324.86 665.53 Tm (cha)Tj 0.145 g 0 Tc 1.468 0 Td (r)Tj 0.29 g 0.0141 Tc 0.368 0 Td (acteristic )Tj 0.0083 Tc 4.337 0 Td (values )Tj 0.05 Tc 11.1292 0 0 10.2 420.37 665.53 Tm (of )Tj 0.0029 Tc 10.2 0 0 10.2 436.3 665.53 Tm (the )Tj 0.0384 Tc 1.882 0 Td (variab)Tj 0.145 g -0.035 Tc 10.0336 0 0 10.2 483.28 665.53 Tm (le)Tj 0.29 g 0 Tc 10.2 0 0 10.2 489.94 665.53 Tm (s )Tj -0.0024 Tc 1.048 0 Td (were )Tj 0.0176 Tc -20.421 -1.083 Td (plotted )Tj -0.0101 Tc 3.432 0 Td (with )Tj 0.0071 Tc 2.259 0 Td (respect )Tj 0.0253 Tc 3.34 0 Td (to )Tj -0.035 Tc 10.1707 0 0 10.2 397.33 654.48 Tm (flow )Tj 0.227 g 0.0351 Tc 10.2 0 0 10.2 419.9 654.48 Tm (during )Tj 0.29 g 0.0261 Tc 3.249 0 Td (inspiration )Tj 0.05 Tc 10.7542 0 0 10.2 503.89 654.48 Tm (an)Tj 0.145 g 0 Tc 10.2 0 0 10.2 514.94 654.48 Tm (d )Tj 0.29 g 0.019 Tc -21.883 -1.082 Td (expiration. )Tj 0.227 g 0.0289 Tc 5.086 0 Td (Inspiratory )Tj 0.29 g 0.037 Tc 5.174 0 Td (and )Tj 0.0218 Tc 2.07 0 Td (expiratory )Tj -0.035 Tc 10.1053 0 0 10.2 467.5 643.44 Tm (va)Tj 0.145 g 0 Tc 10.2 0 0 10.2 477.51 643.44 Tm (l)Tj 0.29 g -0.0069 Tc 0.291 0 Td (ues )Tj 0.05 Tc 11.6856 0 0 10.2 499.09 643.44 Tm (of )Tj 0.227 g 0 Tc 10.2 0 0 10.2 513.51 643.44 Tm (T )Tj 0.29 g 0.037 Tc -21.742 -1.034 Td (and )Tj -0.035 Tc 9.7748 0 0 10.2 312.92 632.89 Tm (PH)Tj 0 Tc 6.9001 0 0 6.9001 324.92 630.48 Tm (2)Tj 10.2 0 0 10.2 328.7 632.89 Tm (o )Tj 0.05 Tc 10.7518 0 0 10.2 339.25 632.89 Tm (at )Tj 0.0265 Tc 10.2 0 0 10.2 352.3 632.89 Tm (the )Tj 0.0139 Tc 1.733 0 Td (airway )Tj 0.0117 Tc 3.247 0 Td (openings )Tj 0.037 Tc 4.188 0 Td (and )Tj 0 Tc 2.035 0 Td (p)Tj 0.145 g 0.05 Tc 10.6764 0 0 10.2 472.3 632.89 Tm (ha)Tj 0.29 g 0.0166 Tc 10.2 0 0 10.2 482.87 632.89 Tm (rynx )Tj 0.227 g 0.05 Tc 10.2757 0 0 10.2 506.78 632.89 Tm (are )Tj 0.29 g 0.0242 Tc 10.2 0 0 10.2 291.7 621.85 Tm (shown )Tj -0.0079 Tc 2.971 0 Td (in )Tj -0.0108 Tc 1.079 0 Td (figures )Tj 0.227 g 0.0204 Tc 3.017 0 Td (2A )Tj 0.29 g 0.037 Tc 1.502 0 Td (and )Tj -0.035 Tc 9.9272 0 0 10.2 397.86 621.85 Tm (2B )Tj 0.0427 Tc 10.2 0 0 10.2 411.73 621.85 Tm (for )Tj 0.0304 Tc 1.507 0 Td (ambient )Tj 0.0437 Tc 3.671 0 Td (air )Tj 0.0296 Tc 1.47 0 Td (breathing )Tj -0.0022 Tc -18.353 -1.083 Td (by )Tj 0 Tc 1.213 0 Td (a )Tj 0.0025 Tc 0.808 0 Td (typical )Tj 0.0182 Tc 3.013 0 Td (normal )Tj 0.0007 Tc 3.234 0 Td (subject. )Tj 0.145 g 0.05 Tc 10.4937 0 0 10.2 410.79 610.8 Tm (Th)Tj 0.29 g 0 Tc 10.2 0 0 10.2 423.25 610.8 Tm (e )Tj 0.0083 Tc 0.621 0 Td (values )Tj 0.05 Tc 11.9795 0 0 10.2 458.76 610.8 Tm (ofT )Tj 10.3398 0 0 10.2 479.41 610.8 Tm (and )Tj 0.227 g -0.035 Tc 10.1658 0 0 10.2 497.71 610.8 Tm (PH)Tj /T1_1 1 Tf 0 Tc 6.2 0 0 6.2 510.67 608.41 Tm (2)Tj /T1_0 1 Tf 10.2 0 0 10.2 514.46 610.8 Tm (o )Tj 0.29 g 0.0128 Tc -21.78 -1.035 Td (tende)Tj 0.145 g 0 Tc 2.204 0 Td (d )Tj 0.29 g 0.0253 Tc 0.949 0 Td (to )Tj 0.0216 Tc 1.176 0 Td (vary )Tj 0.0212 Tc 2.213 0 Td (with )Tj 0.227 g 0.0205 Tc 2.158 0 Td (inspiratory )Tj -0.035 Tc 10.1707 0 0 10.2 431.41 600.24 Tm (flow )Tj 0.29 g -0.0079 Tc 10.2 0 0 10.2 453.04 600.24 Tm (in )Tj 0.0265 Tc 1.182 0 Td (the )Tj 0.227 g 0.0359 Tc 1.651 0 Td (pharynx)Tj 0.388 0.388 0.384 rg 0 Tc 3.512 0 Td (, )Tj 0.29 g 0.0487 Tc -22.101 -1.081 Td (but )Tj 0.0217 Tc 1.691 0 Td (this )Tj 0.0216 Tc 1.788 0 Td (variation )Tj 0.0017 Tc 4.095 0 Td (was )Tj 0.0079 Tc 1.835 0 Td (within )Tj 0 Tc 3.053 0 Td (I )Tj 0.502 g 0.417 0 Td (\260)Tj 0.29 g 0.332 0 Td (C )Tj 0.037 Tc 1.036 0 Td (and )Tj 0.145 g 0 Tc 2.026 0 Td (I )Tj 0.29 g 0.664 0 Td (k)Tj 0.145 g 0.562 0 Td (P)Tj 0.29 g 0.56 0 Td (a )Tj 0.0266 Tc 0.8 0 Td (over )Tj 0.0265 Tc 2.22 0 Td (the )Tj 0.01 Tc -21.081 -1.082 Td (range )Tj 0.05 Tc 11.1292 0 0 10.2 319.57 578.17 Tm (of )Tj 0.0113 Tc 10.2 0 0 10.2 332.05 578.17 Tm (experimental )Tj -0.0306 Tc 5.741 0 Td (flows )Tj 0.037 Tc 2.542 0 Td (and )Tj -0.035 Tc 10.1489 0 0 10.2 436.24 578.17 Tm (is )Tj 0.0387 Tc 10.2 0 0 10.2 446.38 578.17 Tm (more )Tj 0.0231 Tc 2.532 0 Td (evident )Tj 0.227 g 0.0192 Tc 3.482 0 Td (for )Tj 0.29 g 0.0391 Tc -21.174 -1.083 Td (in)Tj 0.388 0.388 0.384 rg 0 Tc 0.794 0 Td (s)Tj 0.227 g 0.0213 Tc 0.439 0 Td (piration )Tj 0.29 g 0.05 Tc 11.1292 0 0 10.2 341.65 567.12 Tm (of )Tj 0.0225 Tc 10.2 0 0 10.2 353.66 567.12 Tm (ambient )Tj 0.0437 Tc 3.718 0 Td (air )Tj 0.0392 Tc 1.514 0 Td (than )Tj 0.05 Tc 10.4873 0 0 10.2 429.59 567.12 Tm (hot )Tj 0 Tc 10.2 0 0 10.2 447.26 567.12 Tm (a)Tj 0.145 g -0.0219 Tc 0.52 0 Td (ir. )Tj 0.227 g 0.05 Tc 10.4358 0 0 10.2 466.03 567.12 Tm (For )Tj 0.29 g 0.0265 Tc 10.2 0 0 10.2 485.26 567.12 Tm (the )Tj 0.227 g -0.0053 Tc 1.591 0 Td (flow )Tj 0.29 g 0.01 Tc -20.508 -1.035 Td (range )Tj 0.0173 Tc 3.093 0 Td (studied)Tj 0.388 0.388 0.384 rg 0 Tc (, )Tj 0.29 g 4.051 0 Td (a)Tj 0.145 g 0.526 0 Td (n )Tj 0.29 g 0.0098 Tc 1.309 0 Td (average )Tj 0.0128 Tc 4.008 0 Td (taken )Tj 0.0109 Tc 3.098 0 Td (over )Tj -0.0224 Tc 2.635 0 Td (all )Tj 0.227 g -0.035 Tc 10.1707 0 0 10.2 501.97 556.56 Tm (flow )Tj 0.29 g 0.0207 Tc 10.2 0 0 10.2 291.74 545.53 Tm (conditions )Tj -0.035 Tc 9.3682 0 0 10.2 340.72 545.53 Tm (is )Tj 0.0206 Tc 10.2 0 0 10.2 350.78 545.53 Tm (adequate. )Tj 0.145 g 0 Tc 4.377 0 Td (T)Tj 0.29 g -0.0102 Tc 0.761 0 Td (hus)Tj 0.388 0.388 0.384 rg 0 Tc 1.397 0 Td (, )Tj 0.29 g -0.035 Tc 9.8086 0 0 10.2 424.31 545.53 Tm (we )Tj 0.0177 Tc 10.2 0 0 10.2 439.58 545.53 Tm (averaged )Tj 0.0029 Tc 4.243 0 Td (the )Tj 0.0332 Tc 1.651 0 Td (peak )Tj -0.0011 Tc -20.333 -1.083 Td (values)Tj 0.388 0.388 0.384 rg 0 Tc 2.575 0 Td (, )Tj 0.29 g 0.0116 Tc 0.675 0 Td (using )Tj 0 Tc 2.633 0 Td (t)Tj 0.145 g 0.33 0 Td (h)Tj 0.29 g -0.0211 Tc 0.565 0 Td (ree )Tj 0.0253 Tc 1.646 0 Td (to )Tj -0.035 Tc 9.8147 0 0 10.2 391.09 534.48 Tm (five )Tj 0.0227 Tc 10.2 0 0 10.2 410.41 534.48 Tm (breaths)Tj 0.388 0.388 0.384 rg 0 Tc 3.042 0 Td (, )Tj 0.29 g 0.05 Tc 11.6856 0 0 10.2 448.21 534.48 Tm (of )Tj 0.0244 Tc 10.2 0 0 10.2 461.65 534.48 Tm (each )Tj 0.0187 Tc 2.362 0 Td (variable )Tj 0.0185 Tc -19.012 -1.082 Td (measured )Tj 0.05 Tc 10.7518 0 0 10.2 336.37 523.44 Tm (at )Tj 0 Tc 10.2 0 0 10.2 349.34 523.44 Tm (a )Tj 0.0256 Tc 0.906 0 Td (particular )Tj 0.0199 Tc 4.46 0 Td (location )Tj 0.0427 Tc 3.763 0 Td (for )Tj 0.0214 Tc 1.697 0 Td (inspiration )Tj 0 Tc 4.986 0 Td (o)Tj 0.145 g 0.574 0 Td (r )Tj 0.29 g 0.0228 Tc -22.033 -1.034 Td (expiration )Tj 0.0445 Tc 4.621 0 Td (thro)Tj 0.145 g 0 Tc 1.743 0 Td (u)Tj 0.29 g 0.0029 Tc 0.556 0 Td (gh )Tj 0.0199 Tc 1.363 0 Td (either )Tj 0.0386 Tc 2.692 0 Td (no)Tj 0.388 0.388 0.384 rg -0.035 Tc 9.9515 0 0 10.2 414.58 512.89 Tm (se )Tj 0.29 g 0.05 Tc 10.5727 0 0 10.2 426.14 512.89 Tm (or )Tj 0.033 Tc 10.2 0 0 10.2 438.7 512.89 Tm (mouth. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0059 Tc 4.8001 0 0 4.8001 290.88 417.37 Tm (UJ )Tj EMC /Suspect <>BDC -0.0327 Tc 7.3001 0 0 7.3001 290.81 412.09 Tm (cr )Tj EMC /Suspect <>BDC -0.035 Tc 3.8762 0 0 6.3001 291.27 406.81 Tm (:::> )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 5.28 0 0 8.16 290.89 397.69 Tm <007E0020>Tj EMC /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 9.912 0 0 7.3001 291.26 393.37 Tm (cr_ )Tj EMC /Suspect <>BDC 9.3654 0 0 6.8001 290.85 387.12 Tm (Wu )Tj EMC /Suspect <>BDC 5.7089 0 0 4.8001 291.3 382.81 Tm (O..o )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 4.8 0 0 3.36 291.36 378 Tm <007E>Tj 0.388 0.388 0.384 rg 6.24 0 0 3.36 299.05 378 Tm <007E0020>Tj EMC /Suspect <>BDC 0.29 g /T1_0 1 Tf -0.0059 Tc 4.8001 0 0 4.8001 290.88 372.72 Tm (UJ)Tj 0.388 0.388 0.384 rg 0.05 Tc 7.529 0 0 4.8001 299.47 372.72 Tm (I-)Tj EMC /Suspect <>BDC 0.29 g -0.035 Tc 6.1944 0 0 10.8 291.23 367.44 Tm (.... )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 5.2077 0 0 3.7001 291.27 359.76 Tm (\(/\) )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 4.8 0 0 4.32 291.36 354 Tm <007E0020>Tj EMC /Suspect <>BDC 5.28 0 0 3.84 291.36 348.72 Tm <007E0020>Tj EMC /Suspect <>BDC /T1_0 1 Tf 0.037 Tc 4.2 0 0 4.2 292.32 249.85 Tm (UJ )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg -0.035 Tc 7.1223 0 0 7.6 292.25 244.57 Tm (a: )Tj EMC /Suspect <>BDC /T1_1 1 Tf 4.7354 0 0 5.9001 292.2 239.76 Tm (::> )Tj EMC /Suspect <>BDC 0.29 g /T1_0 1 Tf 0.05 Tc 4.5667 0 0 3.6 291.82 235.93 Tm (>BDC 4.6871 0 0 3.6 292.27 231.61 Tm (\(/\) )Tj EMC /Suspect <>BDC -0.0059 Tc 4.8001 0 0 4.8001 292.32 226.33 Tm (UJ )Tj EMC /Suspect <>BDC -0.035 Tc 7.1223 0 0 7.6 292.25 221.52 Tm (a: )Tj EMC /Suspect <>BDC -0.0092 Tc 5 0 0 5 292.27 216.73 Tm (0.. )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg /T1_1 1 Tf -0.035 Tc 10.4919 0 0 11.6 292.37 210.97 Tm (_,_ )Tj EMC /Suspect <>BDC 0.29 g /C0_0 1 Tf 0 Tc 6.72 0 0 6.72 292.33 200.41 Tm <007E007E0020>Tj EMC /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 5.6312 0 0 10.2 292.21 197.05 Tm (.... )Tj EMC /Suspect <>BDC 0.227 g /T1_1 1 Tf 6.783 0 0 10.5 300.78 197.05 Tm (.,. )Tj EMC /Suspect <>BDC 0.29 g /T1_0 1 Tf 6.6519 0 0 7.9001 292.26 190.8 Tm (o:)Tj 0.388 0.388 0.384 rg 0 Tc 7.9001 0 0 7.9001 300.39 190.8 Tm (\255)Tj EMC /Suspect <>BDC 0.05 Tc 4.6238 0 0 4.1 292.78 186.97 Tm (<\( )Tj EMC /Suspect <>BDC 0.29 g -0.0092 Tc 5 0 0 5 292.27 182.16 Tm (0.. )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg 0.0352 Tc 6.4001 0 0 6.4001 303.3 182.16 Tm (o., )Tj EMC /Suspect <>BDC 0.29 g /T1_1 1 Tf -0.035 Tc 4.1262 0 0 5.4001 303.73 176.89 Tm (:z: )Tj EMC ET BT /T1_1 1 Tf 0.0451 Tc 6.4001 0 0 6.4001 292.26 173.05 Tm (a:o.. )Tj ET BT /Suspect <>BDC 0.388 0.388 0.384 rg /T1_0 1 Tf 0 Tc 5.4001 0 0 5.4001 292.27 167.76 Tm (0 )Tj EMC /Suspect <>BDC 0.29 g 0.0388 Tc 5 0 0 5 292.27 163.44 Tm (0.. )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 5.28 0 0 7.68 292.33 154.33 Tm <007E0020>Tj EMC /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 5.9598 0 0 5.1 292.26 144.73 Tm (0: )Tj EMC /Suspect <>BDC /T1_1 1 Tf -0.0006 Tc 4.5001 0 0 4.5001 292.22 139.93 Tm (UJ )Tj EMC /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 6.1944 0 0 10.2 292.19 135.61 Tm (.... )Tj EMC /Suspect <>BDC 0.05 Tc 4.6238 0 0 4.1 292.78 131.76 Tm (<\( )Tj EMC /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 5.597 0 0 6.4001 292.73 125.52 Tm (3: )Tj EMC /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 8.5283 0 0 7.9001 312.86 430.81 Tm (36 )Tj EMC /Suspect <>BDC 9.0021 0 0 7.9001 312.38 417.84 Tm (34 )Tj EMC /Suspect <>BDC 8.5283 0 0 7.9001 312.86 405.84 Tm (32 )Tj EMC /Suspect <>BDC 9.4759 0 0 7.9001 312.37 392.89 Tm (30 )Tj EMC /Suspect <>BDC 8.845 0 0 7.9001 312.43 380.41 Tm (28 )Tj EMC ET BT /T1_0 1 Tf 8.845 0 0 7.9001 312.43 367.9278 Tm (26 )Tj 7.9139 0 0 7.9001 312.91 355.44 Tm (24 )Tj ET BT /Suspect <>BDC /C0_0 1 Tf 0 Tc 3.36 0 0 5.76 359.05 487.44 Tm <007E>Tj 0.388 0.388 0.384 rg 4.08 0 0 5.76 363.36 487.44 Tm <00580050>Tj 0.502 g 1.44 0 0 5.76 372.49 487.44 Tm <0049>Tj 0.388 0.388 0.384 rg 4.32 0 0 5.76 374.89 487.44 Tm <00520041>Tj 0.502 g 1.998 0 Td <0054>Tj 0.388 0.388 0.384 rg 3.12 0 0 5.76 388.8 487.44 Tm <0049004F>Tj 0.29 g 3.84 0 0 5.76 396 487.44 Tm <004E0020>Tj EMC ET BT /T1_1 1 Tf 6.5001 0 0 6.5001 405.56 487.44 Tm (} )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 6.5001 0 0 6.5001 358.8633 481.6874 Tm (I)Tj 0.388 0.388 0.384 rg 0.0306 Tc 0.302 0 Td (NSP)Tj 0.502 g 0 Tc 2.135 0 Td (I)Tj 0.388 0.388 0.384 rg 0.374 0 Td (R)Tj 0.29 g 0.689 0 Td (A)Tj 0.388 0.388 0.384 rg 0.05 Tc 6.5797 0 0 6.5001 385.88 481.69 Tm (TIO)Tj 0.29 g 0 Tc 6.5001 0 0 6.5001 397.78 481.69 Tm (N )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg -0.0171 Tc 3.175 0 Td (NOSE )Tj EMC /Suspect <>BDC 0 Tc 3.471 0 Td (B)Tj 0.29 g 0.663 0 Td (R)Tj 0.388 0.388 0.384 rg 0.0459 Tc 0.738 0 Td (EAT)Tj 0.29 g 0.05 Tc 6.7707 0 0 6.5001 463.52 481.69 Tm (HIN)Tj 0.388 0.388 0.384 rg 0 Tc 6.5001 0 0 6.5001 476.06 481.69 Tm (G )Tj EMC /Suspect <>BDC 0.145 g -19.495 -2.363 Td (\225 )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg 1.469 0 Td (E)Tj 0.29 g 0.614 0 Td (X)Tj 0.388 0.388 0.384 rg 0.715 0 Td (P)Tj 0.29 g -0.0014 Tc 0.734 0 Td (IRATION )Tj EMC ET BT 0.388 0.388 0.384 rg /T1_1 1 Tf 0 Tc 6.5001 0 0 6.5001 405.5599 466.3303 Tm (} )Tj ET BT /Suspect <>BDC 0.29 g /T1_1 1 Tf 6.5001 0 0 6.5001 417.4616 466.3303 Tm (M)Tj 0.388 0.388 0.384 rg 0.82 0 Td (O)Tj 0.29 g 0.729 0 Td (U)Tj 0.388 0.388 0.384 rg 0.0104 Tc 0.682 0 Td (TH )Tj EMC /Suspect <>BDC 0 Tc 2.052 0 Td (B)Tj 0.29 g 0.737 0 Td (R)Tj 0.388 0.388 0.384 rg 0.0371 Tc 0.665 0 Td (EA)Tj 0.29 g 0.0144 Tc 1.346 0 Td (THI)Tj 0.388 0.388 0.384 rg -0.035 Tc 6.4382 0 0 6.5001 474.58 466.33 Tm (NG )Tj EMC ET BT /T1_0 1 Tf 0 Tc 6.9001 0 0 6.9001 349.38 460.56 Tm (o )Tj ET BT /Suspect <>BDC 0.227 g /T1_1 1 Tf 0.0158 Tc 6.5001 0 0 6.5001 358.86 460.56 Tm (IN)Tj 0.388 0.388 0.384 rg 0 Tc 1.123 0 Td (S)Tj 0.29 g 0.654 0 Td (P)Tj 0.502 g 0.66 0 Td (I)Tj 0.388 0.388 0.384 rg 0.374 0 Td (R)Tj 0.29 g 0.763 0 Td (A)Tj 0.388 0.388 0.384 rg -0.0131 Tc 0.583 0 Td (TIO)Tj 0.29 g 0 Tc 1.683 0 Td (N )Tj EMC /Suspect <>BDC -9.208 -2.731 Td (A)Tj 0.388 0.388 0.384 rg 0.783 0 Td (I)Tj 0.29 g 0.0195 Tc 0.448 0 Td (RWAY )Tj EMC /Suspect <>BDC 0.0256 Tc 3.849 0 Td (OPEN)Tj 0.388 0.388 0.384 rg 0 Tc 3.088 0 Td (I)Tj 0.29 g -0.035 Tc 6.4382 0 0 6.5001 392.98 442.81 Tm (NG )Tj EMC /Suspect <>BDC 0.05 Tc 6.7845 0 0 6.5001 461.13 442.81 Tm (PHARYNX )Tj EMC /Suspect <>BDC 0.227 g 0 Tc 34.4001 0 0 34.4001 342.27 424.09 Tm (. )Tj EMC ET BT 0.145 g /T1_0 1 Tf -0.035 Tc 6.8183 0 0 15.3 354.58 424.09 Tm (.. )Tj 0.227 g 7.9547 0 0 15.3 366.56 424.09 Tm (.. )Tj ET BT /Suspect <>BDC 0.145 g /T1_1 1 Tf 0 Tc 11.2 0 0 11.2 363.67 416.89 Tm (\225 )Tj EMC /Suspect <>BDC 0.227 g /T1_0 1 Tf 12.3 0 0 12.3 343.48 411.12 Tm (\225 )Tj EMC /Suspect <>BDC 0.145 g /T1_1 1 Tf 11.2 0 0 11.2 371.83 412.56 Tm (\225 )Tj EMC /Suspect <>BDC 34.4001 0 0 34.4001 453.15 431.28 Tm (. )Tj EMC ET BT 0.227 g /T1_1 1 Tf -0.035 Tc 7.2157 0 0 16 466.85 431.28 Tm (.. )Tj ET BT /Suspect <>BDC 0.145 g /T1_1 1 Tf 0 Tc 34.4001 0 0 34.4001 479.55 431.28 Tm (. )Tj EMC /Suspect <>BDC 0.227 g 11.2 0 0 11.2 467.35 423.12 Tm (\225 )Tj EMC /Suspect <>BDC 0.145 g 1.029 0 Td (\225 )Tj EMC /Suspect <>BDC /T1_0 1 Tf 12.3 0 0 12.3 486.52 423.12 Tm (\225 )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg 4.4001 0 0 4.4001 468.92 380.41 Tm (0 )Tj EMC /Suspect <>BDC 0.29 g 1.418 -1.42 Td (0 )Tj EMC ET BT 0.502 g /T1_0 1 Tf 4.4001 0 0 4.4001 493.3978 377.0527 Tm (0 )Tj 0.29 g 0.05 Tc 8.845 0 0 7.9001 312.91 342.97 Tm (22 )Tj ET BT /Suspect <>BDC /C0_0 1 Tf 0 Tc 7.04 0 0 5.76 312.96 331.44 Tm <00320030007E>Tj 0.145 g 9.9429 0 0 5.76 334.08 331.44 Tm <007E007E007E007E007E007E007E0020>Tj EMC /Suspect <>BDC 0.29 g /T1_1 1 Tf 6.8001 0 0 6.8001 324.4 323.76 Tm (0 )Tj EMC ET BT 0.502 g /T1_1 1 Tf 6.8001 0 0 6.8001 334.8586 323.76 Tm (. )Tj 0.29 g 0.443 0 Td (2 )Tj 0.388 0.388 0.384 rg 1.604 0 Td (.)Tj 0.29 g 0.165 0 Td (4 )Tj 0.502 g 1.671 0 Td (.)Tj 0.29 g 0.299 0 Td (6 )Tj ET BT /Suspect <>BDC 0.502 g /T1_1 1 Tf 6.8001 0 0 6.8001 372.7895 323.76 Tm (.)Tj 0.29 g 0.359 0 Td (B )Tj EMC /Suspect <>BDC 0.227 g 1.687 0 Td (I )Tj EMC /Suspect <>BDC 0.29 g 0.44 0 Td (0 )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg 1.532 0 Td (1)Tj 0.502 g 0.288 0 Td (.)Tj 0.29 g 0.372 0 Td (2 )Tj EMC /Suspect <>BDC /T1_0 1 Tf 7.1 0 0 7.1 431.93 323.76 Tm (0 )Tj EMC ET BT 0.227 g /T1_0 1 Tf 7.1 0 0 7.1 445.3987 323.76 Tm (2 )Tj 0.388 0.388 0.384 rg 1.539 0 Td (.)Tj 0.29 g 0.152 0 Td (4 )Tj 0.388 0.388 0.384 rg 1.403 0 Td (.)Tj 0.29 g 0.346 0 Td (6 )Tj ET BT /Suspect <>BDC 0.388 0.388 0.384 rg /T1_0 1 Tf 7.1 0 0 7.1 480.3236 323.76 Tm (.)Tj 0.227 g 0.287 0 Td (B )Tj EMC /Suspect <>BDC 0.29 g -0.0147 Tc 1.593 0 Td (1.0 )Tj EMC ET BT /T1_0 1 Tf -0.035 Tc 6.9277 0 0 7.1 507.12 323.76 Tm (1.2 )Tj 0.388 0.388 0.384 rg 0 Tc 6.8001 0 0 6.8001 315.76 218.65 Tm (6 )Tj 0.29 g 6.4001 0 0 6.4001 316.3 194.16 Tm (4 )Tj 6.5001 0 0 6.5001 316.28 170.65 Tm (2 )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 7.1 0 0 7.1 316.25 147.61 Tm (0 )Tj EMC /Suspect <>BDC 0.946 -1.082 Td (0 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 6.5652 0 0 6.5001 375.68 309.84 Tm (FLOW )Tj EMC /Suspect <>BDC 8.3128 0 0 6.5001 399.69 309.84 Tm (\(liters )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg /T1_3 1 Tf 0 Tc 6.8001 0 0 6.8001 424.21 309.84 Tm (I )Tj EMC ET BT 0.29 g /T1_1 1 Tf 0.05 Tc 7.1348 0 0 6.5001 429.54 309.84 Tm (sec\) )Tj ET BT /Suspect <>BDC 0.145 g /T1_1 1 Tf 0 Tc 6.5001 0 0 6.5001 350.32 285.37 Tm (' )Tj EMC /Suspect <>BDC 0.29 g 1.318 0 Td (E)Tj 0.388 0.388 0.384 rg 0.0005 Tc 0.614 0 Td (XP)Tj 0.227 g 0.0072 Tc 1.375 0 Td (IRA)Tj 0.388 0.388 0.384 rg 0.0238 Tc 1.72 0 Td (TIO)Tj 0.29 g 0 Tc 1.757 0 Td (N )Tj EMC ET BT 0.388 0.388 0.384 rg /T1_1 1 Tf 6.5001 0 0 6.5001 405.5607 285.37 Tm (} )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 6.4513 0 0 6.5001 416.02 285.37 Tm (NOSE )Tj EMC /Suspect <>BDC -0.0014 Tc 6.5001 0 0 6.5001 437.62 285.37 Tm (BREATHI)Tj 0.29 g 0 Tc 4.505 0 Td (N)Tj 0.388 0.388 0.384 rg 0.671 0 Td (G )Tj EMC /Suspect <>BDC 0.0254 Tc -17.366 -0.886 Td (INSPIRATIO)Tj 0.29 g 0 Tc 5.988 0 Td (N )Tj EMC /Suspect <>BDC 24.7001 0 0 24.7001 349.26 263.76 Tm (: )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg /C0_0 1 Tf 4 0 0 11.04 359.05 263.76 Tm <007E003A003A003B007E003A>Tj 0.29 g 4.8 0 0 11.04 382.08 263.76 Tm <003A>Tj 0.388 0.388 0.384 rg 3.84 0 0 11.04 386.4 263.76 Tm <007E007E007E004E0020>Tj EMC ET BT /T1_1 1 Tf 24.7001 0 0 24.7001 405.91 263.76 Tm (} )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 6.2788 0 0 6.5001 415.07 263.76 Tm (MOU)Tj 0.502 g 0 Tc 6.5001 0 0 6.5001 429.56 263.76 Tm (T)Tj 0.388 0.388 0.384 rg 0.648 0 Td (H )Tj EMC /Suspect <>BDC -0.0112 Tc 1.331 0 Td (BRE)Tj 0.29 g 0 Tc 2.165 0 Td (A)Tj 0.388 0.388 0.384 rg -0.035 Tc 6.3559 0 0 6.5001 460.28 263.76 Tm (TH)Tj 0.227 g 0 Tc 6.5001 0 0 6.5001 469.74 263.76 Tm (I)Tj 0.388 0.388 0.384 rg -0.035 Tc 5.7605 0 0 6.5001 471.71 263.76 Tm (NG )Tj EMC /Suspect <>BDC 0.29 g 0.05 Tc 6.5283 0 0 6.5001 337.93 244.09 Tm (AIRWAY )Tj EMC /Suspect <>BDC 0.0256 Tc 6.5001 0 0 6.5001 369.99 244.09 Tm (OPEN)Tj 0.388 0.388 0.384 rg 0 Tc 3.014 0 Td (I)Tj 0.227 g -0.035 Tc 6.4382 0 0 6.5001 392.5 244.09 Tm (NG )Tj EMC /Suspect <>BDC 0.29 g 0.0379 Tc 6.5001 0 0 6.5001 456.81 244.57 Tm (PHARYNX )Tj EMC ET BT 0.773 g /T1_0 1 Tf -0.035 Tc 15.1622 0 0 18.6 334.38 218.65 Tm (----)Tj 0.698 g /T1_1 1 Tf 5.1541 0 0 11 354.58 218.65 Tm (.. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0046 Tc 15.4 0 0 15.4 359.34 218.65 Tm (--\267-----)Tj EMC /Suspect <>BDC 0.227 g /T1_1 1 Tf 0 Tc 11.2 0 0 11.2 367.99 198.49 Tm (\225 )Tj EMC /Suspect <>BDC 0.145 g 13.1 0 0 13.1 364.12 193.21 Tm (\225 )Tj EMC /Suspect <>BDC 0.29 g /T1_2 1 Tf 5.6 0 0 5.6 366.2 167.29 Tm (b )Tj EMC /Suspect <>BDC 0.502 g 4.4001 0 0 4.4001 339.29 160.57 Tm (0 )Tj EMC /Suspect <>BDC 0.29 g /T1_0 1 Tf 4.7 0 0 4.7 348.43 160.57 Tm (0 )Tj EMC /Suspect <>BDC 0.6 g /T1_1 1 Tf 4.9001 0 0 4.9001 356.17 157.69 Tm (A )Tj EMC /Suspect <>BDC 0.698 g 3.8001 0 0 3.8001 368.6 158.16 Tm (0 )Tj EMC ET BT 0.388 0.388 0.384 rg /T1_1 1 Tf 6.3001 0 0 6.3001 336.91 139.93 Tm (2 )Tj 0.6 g /T1_0 1 Tf 6.4001 0 0 6.4001 347.87 140.41 Tm (.)Tj 0.29 g 0.166 0 Td (4 )Tj 6.8001 0 0 6.8001 360.88 139.93 Tm (6 )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 6.5001 0 0 6.5001 372.34 139.93 Tm (B )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg /T1_2 1 Tf 4.4001 0 0 4.4001 376.73 167.29 Tm (0 )Tj EMC /Suspect <>BDC 0.145 g /T1_1 1 Tf 8.5 0 0 8.5 452.53 210.01 Tm (' )Tj EMC /Suspect <>BDC 0.227 g 0.05 Tc 8.53 0 0 8.5 462.61 210.01 Tm ('\225 )Tj EMC /Suspect <>BDC 0.145 g /T1_3 1 Tf 16.9658 0 0 8.5 475.87 210.01 Tm (I. )Tj EMC /Suspect <>BDC 0.698 g /T1_0 1 Tf 0 Tc 4.4001 0 0 4.4001 472.76 170.65 Tm (0 )Tj EMC /Suspect <>BDC 0.502 g 5.4001 0 0 5.4001 477.06 190.33 Tm (6 )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg 2.222 0 Td (6 )Tj EMC /Suspect <>BDC 4.4001 0 0 4.4001 489.56 181.21 Tm (0 )Tj EMC /Suspect <>BDC 0.145 g /T1_1 1 Tf 6.5001 0 0 6.5001 383.34 140.41 Tm (I )Tj EMC /Suspect <>BDC 0.29 g /T1_0 1 Tf 7.1 0 0 7.1 386.81 140.41 Tm (0 )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg /T1_1 1 Tf 6.5001 0 0 6.5001 395.34 140.41 Tm (I )Tj EMC ET BT 0.29 g /T1_0 1 Tf 7.1 0 0 7.1 399.8 140.41 Tm (2 )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 6.5001 0 0 6.5001 430.96 140.41 Tm (0 )Tj EMC ET BT 0.773 g /T1_1 1 Tf 6.5001 0 0 6.5001 440.9507 140.41 Tm (.)Tj 0.29 g 0.388 0 Td [(2 )-943(4 )]TJ 0.502 g 3.452 0 Td (.)Tj 0.29 g 0.237 0 Td (6 )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 6.5001 0 0 6.5001 479.3792 140.41 Tm (B )Tj EMC /Suspect <>BDC 0.227 g -0.035 Tc 6.2371 0 0 6.5001 490.84 140.41 Tm (1.0 )Tj EMC /Suspect <>BDC 0.388 0.388 0.384 rg 0 Tc 6.5001 0 0 6.5001 502.38 140.41 Tm (I )Tj EMC ET BT 0.29 g /T1_1 1 Tf 6.5001 0 0 6.5001 506.3516 140.41 Tm (2 )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.0108 Tc 6.5001 0 0 6.5001 376.6486 125.9993 Tm (FLOW )Tj EMC /Suspect <>BDC 0.05 Tc 8.3605 0 0 6.5001 397.71 126 Tm (!liters/sec\) )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.2 0 0 8.2 291.33 111.12 Tm (F)Tj 0.388 0.388 0.384 rg 0.58 0 Td (i)Tj 0.29 g -0.0329 Tc 0.234 0 Td (g. )Tj 0 Tc 1.056 0 Td (2)Tj 0.388 0.388 0.384 rg 0.512 0 Td (. )Tj 0.29 g 0.0196 Tc 1.301 0 Td (Inspiratory )Tj 0.045 Tc 4.856 0 Td (and )Tj 0.0208 Tc 1.813 0 Td (expiratory )Tj 0.227 g 0 Tc 4.568 0 Td (T )Tj 0.29 g 0.05 Tc 8.4599 0 0 8.2 420.87 111.12 Tm (and )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 7.8198 0 0 8.2 435.81 111.12 Tm (PH)Tj 0.388 0.388 0.384 rg /T1_1 1 Tf 0 Tc 5.3001 0 0 5.3001 445.88 109.2 Tm (2)Tj 0.29 g /T1_0 1 Tf 8.2 0 0 8.2 448.72 111.12 Tm (o )Tj EMC ET BT /T1_2 1 Tf -0.035 Tc 8.0907 0 0 8.7 455.95 111.12 Tm (versu)Tj 0.388 0.388 0.384 rg 0 Tc 8.7 0 0 8.7 472.35 111.12 Tm (s )Tj ET BT /Suspect <>BDC 0.29 g /T1_0 1 Tf 0.0182 Tc 8.2 0 0 8.2 477.61 111.12 Tm (peak )Tj EMC ET BT /T1_0 1 Tf -0.0317 Tc 8.2 0 0 8.2 495.2728 111.12 Tm (flow )Tj 0.05 Tc 8.222 0 0 8.2 512.08 111.12 Tm (at )Tj 0.0449 Tc 8.2 0 0 8.2 290.86 102 Tm (th)Tj 0.388 0.388 0.384 rg 0 Tc 0.811 0 Td (e )Tj 0.29 g 0.821 0 Td (a)Tj 0.145 g 0.47 0 Td (i)Tj 0.29 g 0.017 Tc 0.3 0 Td (rway )Tj 0.0228 Tc 2.391 0 Td (opening )Tj 0.045 Tc 3.688 0 Td (and )Tj 0 Tc 1.943 0 Td (p)Tj 0.145 g 0.524 0 Td (h)Tj 0.29 g 0.0191 Tc 0.518 0 Td (arynx )Tj 0.05 Tc 8.9033 0 0 8.2 407.43 102 Tm (of )Tj 0 Tc 8.2 0 0 8.2 417.52 102 Tm (a )Tj 0.02 Tc 0.828 0 Td (normal )Tj 0 Tc 3.323 0 Td (s)Tj 0.145 g 0.424 0 Td (u)Tj 0.29 g 0.0003 Tc 0.528 0 Td (bject )Tj 0.03 Tc 2.272 0 Td (during )Tj -0.0047 Tc 3.111 0 Td (nose )Tj 0.227 g 0.045 Tc -25.94 -1.054 Td (and )Tj 0.29 g 0.0358 Tc 1.822 0 Td (mouth )Tj 0.0271 Tc 2.989 0 Td (breathing )Tj 0.05 Tc 8.9033 0 0 8.2 364.71 93.36 Tm (of )Tj 0.0315 Tc 8.2 0 0 8.2 373.84 93.36 Tm (ambient )Tj 0.0091 Tc 3.629 0 Td (air: )Tj 0 Tc 1.648 0 Td (A)Tj 0.502 g 0.8 0 Td (. )Tj ET BT /Suspect <>BDC 0.29 g /T1_0 1 Tf 0.05 Tc 8.4933 0 0 8.2 427.12 93.36 Tm (Gas )Tj EMC ET BT /T1_0 1 Tf 0.0151 Tc 8.2 0 0 8.2 443.02 93.36 Tm (temperature; )Tj 0.145 g -0.035 Tc 7.2609 0 0 8.2 488.61 93.36 Tm (B. )Tj 0.227 g 0.0358 Tc 8.2 0 0 8.2 497.73 93.36 Tm (Water )Tj 0.29 g 0.013 Tc -25.228 -1.111 Td (vap)Tj 0.388 0.388 0.384 rg 0 Tc 1.515 0 Td (o)Tj 0.29 g 0.0456 Tc 0.537 0 Td (ur )Tj 0.0253 Tc 1.172 0 Td (partial )Tj 0.0104 Tc 2.985 0 Td (pre)Tj 0.388 0.388 0.384 rg 0 Tc 1.272 0 Td (s)Tj 0.29 g 0.0193 Tc 0.41 0 Td (sure )Tj 0.0104 Tc 1.993 0 Td (\(equilib)Tj 0.388 0.388 0.384 rg -0.0243 Tc 3.172 0 Td (ri)Tj 0.29 g 0.0114 Tc 0.645 0 Td (um )Tj 0.032 Tc 1.579 0 Td (water )Tj 0.0313 Tc 2.574 0 Td (vapour )Tj 0.0106 Tc 3.165 0 Td (pressure )Tj 0.05 Tc 8.8544 0 0 8.2 492.87 84.25 Tm (at )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 8.275 0 0 8.5 501.98 84.25 Tm (37)Tj 0.388 0.388 0.384 rg 0 Tc 8.5 0 0 8.5 509.63 84.25 Tm (\225)Tj 0.29 g 0.401 0 Td (c )Tj EMC ET BT /T1_0 1 Tf 0.0267 Tc 8.2 0 0 8.2 290.28 75.6 Tm (shown )Tj 0.0047 Tc 3.118 0 Td (by )Tj 0.227 g 0.0058 Tc 1.343 0 Td (the )Tj 0.29 g 0.0205 Tc 1.573 0 Td (dashed )Tj 0.227 g -0.0061 Tc 3.279 0 Td (line)Tj 0.388 0.388 0.384 rg 0 Tc 1.466 0 Td (\))Tj 0.29 g 0.337 0 Td (. )Tj ET endstream endobj 16 0 obj <>stream Hd͊zy8 >sRhF^#y QG#Oç==o/ϧ;c_mӷKv|~_oo~y>}~W=|z>{O݇q~?>Ï?o+~ߒ~;%zΏx߽w;>lp?(O?{wٸ^ PZUuTGu^5P5FjFDMԤU PjVjUmFmک]uPuNNE]E5|| _#_k55|| _#_k55|| _#_k55|| 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EMC /Suspect <>BDC 8.8221 0 0 7.6 270.2 754.8 Tm (PRIMIANO )Tj EMC ET BT 0.239 g /T1_0 1 Tf 8.4 0 0 7.6 321.07 754.8 Tm (ET )Tj 8.371 0 0 7.6 335.99 754.8 Tm (AL)Tj 0.447 0.447 0.443 rg 0 Tc 7.6 0 0 7.6 348.8 754.8 Tm (. )Tj ET BT /Suspect <>BDC 0.239 g /T1_0 1 Tf 0.0229 Tc 10.4 0 0 10.4 71.03 730.8 Tm (Under )Tj EMC ET BT /T1_0 1 Tf 0.0118 Tc 10.4 0 0 10.4 102.6148 730.8 Tm (ambient )Tj 0.0084 Tc 3.693 0 Td (conditions, )Tj -0.0088 Tc 4.991 0 Td (the )Tj 0.0055 Tc 1.609 0 Td (changes )Tj -0.0224 Tc 3.693 0 Td (in )Tj 0 Tc 1.2 0 Td (T )Tj 0.0456 Tc 1.06 0 Td (and )Tj ET BT /Suspect <>BDC 0.176 g /T1_0 1 Tf -0.035 Tc 9.3838 0 0 10.4 60.92 720.24 Tm (PH)Tj 0 Tc 6.9001 0 0 6.9001 72.92 717.36 Tm (2)Tj 10.4 0 0 10.4 76.7 720.24 Tm (o )Tj EMC ET BT 0.239 g /T1_0 1 Tf -0.0146 Tc 10.4 0 0 10.4 87.3704 720.24 Tm (between )Tj 0.0082 Tc 3.729 0 Td (inspiration )Tj 0.0225 Tc 4.798 0 Td (and )Tj 0.0137 Tc 1.938 0 Td (expiration )Tj 0.0191 Tc 4.615 0 Td (are )Tj -0.035 Tc 9.9195 0 0 10.4 262 720.24 Tm (in )Tj 0.176 g 0.0143 Tc 10.4 0 0 10.4 274.53 720.24 Tm (the )Tj 0.239 g 0.0013 Tc -20.596 -1.061 Td (same )Tj 0.0074 Tc 2.589 0 Td (direction )Tj -0.0022 Tc 4.211 0 Td (because )Tj -0.0088 Tc 3.735 0 Td (the )Tj -0.0102 Tc 1.759 0 Td (processes )Tj 0.05 Tc 11.1292 0 0 10.4 233.17 709.21 Tm (of )Tj 0.0008 Tc 10.4 0 0 10.4 248.15 709.21 Tm (heat )Tj 0.0225 Tc 2.252 0 Td (and )Tj 0.176 g 0.012 Tc -20.298 -1.062 Td (water )Tj 0.239 g -0.002 Tc 2.713 0 Td (exchange )Tj 0.0191 Tc 4.2 0 Td (are )Tj 0.0104 Tc 1.708 0 Td (analogous, )Tj /T1_1 1 Tf -0.0171 Tc 4.89 0 Td (i.e., )Tj /T1_0 1 Tf -0.0088 Tc 1.948 0 Td (the )Tj -0.0137 Tc 1.7 0 Td (energy )Tj 0.0225 Tc 3.138 0 Td (and )Tj 0.012 Tc -20.298 -1.015 Td (water )Tj 0.0088 Tc 2.54 0 Td (balance )Tj 0.0142 Tc 3.312 0 Td (equations )Tj 0.0225 Tc 4.2 0 Td (and )Tj 0.0224 Tc 1.812 0 Td (boundary )Tj 0.0166 Tc 4.143 0 Td (conditions )Tj 0.0191 Tc 4.568 0 Td (are )Tj 0.0036 Tc -20.588 -1.062 Td (similar )Tj 0.0074 Tc 3.095 0 Td (for )Tj 0.176 g 0 Tc 1.526 0 Td (T )Tj 0.329 g 0.921 0 Td (a)Tj 0.176 g 0.0187 Tc 0.517 0 Td (nd )Tj ET BT /Suspect <>BDC /T1_2 1 Tf 0.05 Tc 7.8745 0 0 7.7 137.58 676.56 Tm (PH)Tj /T1_0 1 Tf 0 Tc 6.4001 0 0 6.4001 149.72 674.17 Tm (2)Tj /T1_2 1 Tf 7.7 0 0 7.7 153.51 676.56 Tm (0 )Tj EMC ET BT 0.239 g /T1_0 1 Tf -0.035 Tc 9.4074 0 0 10.4 162.01 676.56 Tm ([3\). )Tj 0.176 g 0.0135 Tc 10.4 0 0 10.4 177.99 676.56 Tm (This )Tj 0.239 g 0.0041 Tc 2.134 0 Td (provides )Tj 0 Tc 3.772 0 Td (a )Tj -0.0119 Tc 0.786 0 Td (check )Tj 0.0074 Tc 2.629 0 Td (for )Tj -0.0026 Tc -20.629 -1.061 Td (consistency )Tj 0.05 Tc 11.1292 0 0 10.4 113.17 665.53 Tm (of )Tj 0.0143 Tc 10.4 0 0 10.4 127.17 665.53 Tm (the )Tj 0.0118 Tc 1.702 0 Td (independent )Tj 0.0054 Tc 5.453 0 Td (measurements )Tj 0.0075 Tc 6.267 0 Td (from )Tj 0.0143 Tc -19.838 -1.015 Td (the )Tj 0.0086 Tc 1.8 0 Td (transducers. )Tj 0.176 g -0.0052 Tc 5.537 0 Td (Results )Tj 0.239 g 0.0074 Tc 3.455 0 Td (for )Tj 0.0327 Tc 1.811 0 Td (hot )Tj 0.0098 Tc 1.883 0 Td (air )Tj 0.0142 Tc 1.673 0 Td (breathing )Tj 0.0191 Tc 4.419 0 Td (are )Tj -0.0003 Tc -20.588 -1.063 Td (shown )Tj -0.035 Tc 9.9195 0 0 10.4 92.08 643.92 Tm (in )Tj -0.0272 Tc 10.4 0 0 10.4 103.56 643.92 Tm (figures )Tj -0.035 Tc 10.0166 0 0 10.4 135.24 643.92 Tm (3A )Tj 0.0225 Tc 10.4 0 0 10.4 151.57 643.92 Tm (and )Tj -0.035 Tc 10.2666 0 0 10.4 171.24 643.92 Tm (3B. )Tj 0.0394 Tc 10.4 0 0 10.4 188.55 643.92 Tm (The )Tj 0.176 g -0.0038 Tc 2.038 0 Td (results )Tj 0.239 g -0.0174 Tc 2.945 0 Td (differ )Tj -0.0079 Tc 2.537 0 Td (from )Tj 0.0041 Tc -19.838 -1.061 Td (those )Tj 0.0244 Tc 2.347 0 Td (during )Tj 0.0195 Tc 2.907 0 Td (ambient )Tj 0.0329 Tc 3.554 0 Td (air )Tj 0.0142 Tc 1.35 0 Td (breathing )Tj -0.0224 Tc 4.098 0 Td (in )Tj 0.329 g 0.0402 Tc 1.021 0 Td (that )Tj 0.239 g 0.0143 Tc 1.846 0 Td (the )Tj 0.0055 Tc 1.47 0 Td (changes )Tj -0.0224 Tc -18.599 -1.015 Td (in )Tj 0.176 g 0 Tc 1.292 0 Td (T )Tj 0.239 g 0.0456 Tc 1.198 0 Td (and )Tj ET BT /Suspect <>BDC 0.176 g /T1_2 1 Tf -0.035 Tc 8.7472 0 0 9 108.28 622.33 Tm (PH)Tj /T1_0 1 Tf 0 Tc 6.2 0 0 6.2 120.93 619.92 Tm (2)Tj 10.4 0 0 10.4 124.7 622.33 Tm (o )Tj EMC ET BT 0.239 g /T1_0 1 Tf 0.0358 Tc 10.4 0 0 10.4 136.2232 622.33 Tm (on )Tj 0.0174 Tc 1.57 0 Td (inspiration )Tj 0.05 Tc 11.1292 0 0 10.4 204.37 622.33 Tm (of )Tj 0.176 g 10.4873 0 0 10.4 218.87 622.33 Tm (hot )Tj 0.239 g 0.0329 Tc 10.4 0 0 10.4 238.93 622.33 Tm (air )Tj 0.176 g 0.0244 Tc 1.663 0 Td (do )Tj 0.239 g 0.05 Tc 10.4827 0 0 10.4 273.11 622.33 Tm (not )Tj 0.0129 Tc 10.4 0 0 10.4 59.9 611.29 Tm (correspond. )Tj -0.0019 Tc 5.36 0 Td (With )Tj -0.0088 Tc 2.539 0 Td (the )Tj 0.176 g -0.0269 Tc 1.71 0 Td (ho)Tj 0.329 g 0 Tc 1.06 0 Td (t )Tj 0.239 g 0.004 Tc 0.733 0 Td (inspired )Tj 0.0001 Tc 3.737 0 Td (air, )Tj 0.0143 Tc 1.854 0 Td (the )Tj 0.0194 Tc 1.708 0 Td (transfer )Tj -0.0102 Tc -18.641 -1.062 Td (processes )Tj 0.05 Tc 11.1292 0 0 10.4 102.13 600.24 Tm (of )Tj 0.0316 Tc 10.4 0 0 10.4 113.27 600.24 Tm (heat )Tj 0.0225 Tc 1.975 0 Td (and )Tj 0.012 Tc 1.763 0 Td (water )Tj 0.0422 Tc 2.483 0 Td (are )Tj -0.0224 Tc 1.525 0 Td (in )Tj 0.0137 Tc 1.014 0 Td (opposite )Tj 0.002 Tc 3.692 0 Td (directions. )Tj 0.0154 Tc -16.616 -1.015 Td (Complete )Tj 0.0487 Tc 4.662 0 Td (data )Tj 0.0014 Tc 2.441 0 Td (sets )Tj -0.0301 Tc 2.229 0 Td (were )Tj 0.0192 Tc 2.53 0 Td (obtained )Tj 0.0075 Tc 4.29 0 Td (from )Tj 0.0208 Tc 2.686 0 Td (three )Tj 0.007 Tc -19.752 -1.061 Td (normal )Tj -0.0012 Tc 3.31 0 Td (subjects )Tj 0.0456 Tc 3.558 0 Td (and )Tj -0.0079 Tc 1.937 0 Td (from )Tj 0.0075 Tc 2.4 0 Td (four )Tj 0.05 Tc 11.1325 0 0 10.4 198.6 578.65 Tm (CF )Tj 0.176 g 0.0085 Tc 10.4 0 0 10.4 216.5 578.65 Tm (patients. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.002 Tc 10.4 0 0 10.4 257.2056 578.65 Tm (Incom\255)Tj EMC ET BT 0.239 g /T1_0 1 Tf -0.0097 Tc 10.4 0 0 10.4 60.5 567.6052 Tm (plete )Tj 0.0487 Tc 2.342 0 Td (data )Tj -0.014 Tc 2.303 0 Td (sets )Tj -0.0147 Tc 1.906 0 Td (were )Tj -0.0042 Tc 2.345 0 Td (caused )Tj -0.035 Tc 10.0218 0 0 10.4 186.73 567.61 Tm (by: )Tj -0.0143 Tc 10.4 0 0 10.4 204.36 567.61 Tm (\(a\) )Tj 0.0143 Tc 1.578 0 Td (the )Tj 0.0014 Tc 1.748 0 Td (inability )Tj 0.05 Tc 10.5727 0 0 10.4 278.78 567.61 Tm (of )Tj -0.0023 Tc 10.4 0 0 10.4 59.85 556.56 Tm (some )Tj -0.0012 Tc 2.354 0 Td (subjects )Tj 0.01 Tc 3.473 0 Td (to )Tj 0.329 g 1.062 0 Td (to)Tj 0.176 g 0.0122 Tc 0.825 0 Td (lerate )Tj 0.239 g 0.0143 Tc 2.498 0 Td (the )Tj 0.0217 Tc 1.482 0 Td (probe )Tj 0.0238 Tc 2.574 0 Td (in )Tj 0.0143 Tc 1.021 0 Td (the )Tj 0.0165 Tc 1.516 0 Td (oropharynx; )Tj 0.0034 Tc -16.802 -1.015 Td (\(b\) )Tj 0.0215 Tc 1.659 0 Td (saturation )Tj 0.05 Tc 11.1292 0 0 10.4 125.65 546 Tm (of )Tj -0.0088 Tc 10.4 0 0 10.4 139.65 546 Tm (the )Tj 0.329 g 0.0158 Tc 1.708 0 Td (thermistor )Tj 0.176 g -0.0079 Tc 4.745 0 Td (from )Tj 0.239 g 0 Tc 2.447 0 Td (a )Tj 0.021 Tc 0.924 0 Td (coating )Tj 0.05 Tc 10.5727 0 0 10.4 278.78 546 Tm (of )Tj -0.004 Tc 10.4 0 0 10.4 59.98 534.97 Tm (mucus; )Tj -0.035 Tc 10.352 0 0 10.4 93.48 534.97 Tm (\(c\) )Tj -0.0053 Tc 10.4 0 0 10.4 108.02 534.97 Tm (plugging )Tj 0.05 Tc 11.1292 0 0 10.4 147.73 534.97 Tm (of )Tj -0.0088 Tc 10.4 0 0 10.4 160.29 534.97 Tm (the )Tj 0.028 Tc 1.569 0 Td (tip )Tj 0.05 Tc 11.1292 0 0 10.4 191.41 534.97 Tm (of )Tj 0.0143 Tc 10.4 0 0 10.4 203.49 534.97 Tm (the )Tj 0.0043 Tc 1.62 0 Td (probe. )Tj /T1_2 1 Tf 0.05 Tc 7.5528 0 0 6.2 82.06 417.37 Tm (46 )Tj 0 Tc 6.2 0 0 6.2 61.92 404.41 Tm (w )Tj 0.05 Tc 7.5528 0 0 6.2 82.06 404.89 Tm (44)Tj 0.553 g 0 Tc 6.2 0 0 6.2 92.59 404.89 Tm (-)Tj ET BT /Suspect <>BDC 0.239 g /T1_0 1 Tf 0.05 Tc 5.9598 0 0 5.1 61.86 399.61 Tm (0: )Tj EMC /Suspect <>BDC 0.329 g /T1_2 1 Tf -0.035 Tc 3.8228 0 0 5.9001 61.82 394.81 Tm (:::> )Tj EMC ET BT 0.239 g /T1_2 1 Tf 0.05 Tc 6.7136 0 0 6.2 83.02 393.37 Tm (42)Tj 0.553 g 0 Tc 6.2 0 0 6.2 92.59 393.37 Tm (-)Tj ET BT /Suspect <>BDC 0.176 g /T1_0 1 Tf 0.05 Tc 5.9143 0 0 5.1 61.24 390.49 Tm (1-)Tj EMC /Suspect <>BDC 0.239 g -0.035 Tc 5.4456 0 0 5.8001 61.9 386.65 Tm (>BDC /T1_2 1 Tf 0.05 Tc 8.8286 0 0 6.4001 61.84 382.33 Tm (o:_ )Tj EMC /Suspect <>BDC 0.176 g 7.9724 0 0 6.2 82.05 381.37 Tm (40)Tj 0.447 0.447 0.443 rg 0 Tc 6.2 0 0 6.2 92.59 381.37 Tm (-)Tj EMC ET BT 0.239 g /T1_0 1 Tf 0.05 Tc 10.6032 0 0 7.6 61.42 377.05 Tm (wo )Tj 0.176 g 10.6983 0 0 6.4001 61.33 373.21 Tm (a.. )Tj ET BT /Suspect <>BDC 0.239 g /T1_2 1 Tf 7.6067 0 0 6.2 81.99 368.89 Tm (38 )Tj EMC /Suspect <>BDC /T1_0 1 Tf 12.3624 0 0 9.3 61.61 367.93 Tm (:s-)Tj EMC /Suspect <>BDC 9.0785 0 0 5.1 61.43 363.61 Tm (wl-)Tj EMC /Suspect <>BDC 5.9143 0 0 5.1 61.24 358.33 Tm (1-)Tj EMC /Suspect <>BDC /T1_2 1 Tf 7.6067 0 0 6.2 81.99 357.84 Tm (36 )Tj EMC /Suspect <>BDC -0.035 Tc 10.9747 0 0 11.9 61.29 345.37 Tm ("' )Tj EMC /Suspect <>BDC /T1_0 1 Tf 5.4456 0 0 5.8001 61.9 345.84 Tm (>BDC /T1_2 1 Tf 0.05 Tc 7.6067 0 0 6.2 81.99 345.84 Tm (34 )Tj EMC /Suspect <>BDC 0.329 g -0.035 Tc 3.5837 0 0 4.9001 61.87 341.05 Tm ( )Tj EMC /Suspect <>BDC 0.239 g 0.05 Tc 7.1841 0 0 6.2 82.47 333.84 Tm (32 )Tj EMC /Suspect <>BDC 8.0293 0 0 6.2 81.5 322.33 Tm (30 )Tj EMC /Suspect <>BDC 0.329 g 0 Tc 6.2 0 0 6.2 92.57 314.65 Tm (0 )Tj EMC ET BT /T1_2 1 Tf 6.4001 0 0 6.4001 59.04 245.05 Tm (w )Tj ET BT /Suspect <>BDC 0.176 g /T1_2 1 Tf 6 0 0 6 123.29 472.56 Tm (' )Tj EMC /Suspect <>BDC 0.329 g 0.05 Tc 6.0195 0 0 6 131.38 472.56 Tm (EXPIRATION )Tj EMC ET BT /T1_2 1 Tf 0 Tc 6 0 0 6 176.6 472.56 Tm (} )Tj ET BT /Suspect <>BDC /T1_2 1 Tf 0.0321 Tc 6 0 0 6 187.55 472.56 Tm (NOSE )Tj EMC /Suspect <>BDC 0.0362 Tc 3.52 0 Td (BREATHING )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 3.36 0 0 4.8 122.88 467.28 Tm <007E0020>Tj EMC /Suspect <>BDC 0.239 g /T1_2 1 Tf 0.0393 Tc 6 0 0 6 131.36 467.28 Tm (INSPIRATION )Tj EMC /Suspect <>BDC 0 Tc -1.348 -2.078 Td (\225 )Tj EMC /Suspect <>BDC 0.329 g 0.0274 Tc 1.352 0 Td (EXPIRA)Tj 0.447 0.447 0.443 rg 0 Tc 3.777 0 Td (T)Tj 0.329 g 0.0194 Tc 0.7 0 Td (ION )Tj EMC ET BT /T1_2 1 Tf 0 Tc 6 0 0 6 176.606 454.812 Tm (} )Tj ET BT /Suspect <>BDC 0.239 g /T1_2 1 Tf -0.0047 Tc 6 0 0 6 186.596 454.812 Tm (MOUTH )Tj EMC /Suspect <>BDC 0.329 g 0.0262 Tc 4.32 0 Td (BREATHING )Tj EMC ET BT /T1_0 1 Tf 0 Tc 6.4001 0 0 6.4001 123.3 449.53 Tm (o )Tj ET BT /Suspect <>BDC 0.239 g /T1_2 1 Tf -0.0051 Tc 6 0 0 6 131.84 449.53 Tm (INS)Tj 0.447 0.447 0.443 rg 0 Tc 1.685 0 Td (P)Tj 0.329 g 0.0273 Tc 0.715 0 Td (IRATION )Tj EMC /Suspect <>BDC 0.239 g 0.05 Tc 6.4137 0 0 6 110.89 432.72 Tm (AIRWAY )Tj EMC /Suspect <>BDC 6.1979 0 0 6 142.48 432.72 Tm (OPENING )Tj EMC /Suspect <>BDC 6.3134 0 0 6 227.86 432.25 Tm (PHARYNX )Tj EMC /Suspect <>BDC 0.176 g 0 Tc 11.2 0 0 11.2 118.87 355.44 Tm (\225 )Tj EMC /Suspect <>BDC 13.1 0 0 13.1 122.68 348.72 Tm (\225 )Tj EMC /Suspect <>BDC 0.329 g 3.8001 0 0 3.8001 126.2 398.16 Tm (0 )Tj EMC /Suspect <>BDC 0.239 g /T1_0 1 Tf 12.3 0 0 12.3 145.24 364.09 Tm (\225 )Tj EMC /Suspect <>BDC 0.329 g /C0_0 1 Tf 3.36 0 0 3.36 155.53 420.72 Tm <007E0020>Tj EMC /Suspect <>BDC 0.553 g 2.88 0 0 3.84 156 415.44 Tm <007E0020>Tj EMC /Suspect <>BDC 0.329 g /T1_2 1 Tf 3.8001 0 0 3.8001 167.96 409.21 Tm (0 )Tj EMC /Suspect <>BDC 0.239 g 3.5001 0 0 3.5001 234.2 366 Tm (0 )Tj EMC ET BT 0.176 g /T1_2 1 Tf 4.6 0 0 4.6 234.66 359.28 Tm (' )Tj ET BT /Suspect <>BDC /T1_2 1 Tf 0.05 Tc 4.9548 0 0 4.6 241.93 359.28 Tm (Am )Tj EMC ET BT /T1_2 1 Tf 0 Tc 25.2001 0 0 25.2001 229.72 357.84 Tm (. )Tj ET BT /Suspect <>BDC 0.239 g /T1_3 1 Tf 4.8001 0 0 4.8001 224.12 349.69 Tm (b )Tj EMC /Suspect <>BDC 0.329 g /T1_2 1 Tf 2.094 0 Td (\225 )Tj EMC /Suspect <>BDC 0.239 g 2.8 0 Td (\225 )Tj EMC /Suspect <>BDC 0.329 g /T1_0 1 Tf 4.4001 0 0 4.4001 256.28 366.97 Tm (0 )Tj EMC /Suspect <>BDC /T1_2 1 Tf 6.2 0 0 6.2 105.07 315.12 Tm (2 )Tj EMC ET BT 0.239 g /T1_2 1 Tf 6.2 0 0 6.2 116.137 315.12 Tm [(4 )-1172(6 )-1090(B )]TJ ET BT /Suspect <>BDC 0.329 g /T1_2 1 Tf 6.2 0 0 6.2 151.477 315.12 Tm (1)Tj 0.702 g 0.239 0 Td (.)Tj 0.239 g 0.247 0 Td (0 )Tj EMC /Suspect <>BDC 1.377 0 Td (I )Tj EMC /Suspect <>BDC 0.561 0 Td (2 )Tj EMC /Suspect <>BDC 0.329 g -0.035 Tc 5.8473 0 0 6.2 175.49 315.12 Tm (1.4 )Tj EMC /Suspect <>BDC 0 Tc 6.2 0 0 6.2 193.85 315.12 Tm (0 )Tj EMC /Suspect <>BDC 0.239 g 1.939 0 Td (2 )Tj EMC ET BT /T1_2 1 Tf 6.2 0 0 6.2 216.9388 315.12 Tm [(4 )-1095(6 )]TJ 6.2 0 0 6.2 193.85 315.12 Tm 7.664 0 Td (8 )Tj ET BT /Suspect <>BDC 0.329 g /T1_2 1 Tf -0.0313 Tc 6.2 0 0 6.2 252.2788 315.12 Tm (1.0 )Tj EMC /Suspect <>BDC 0 Tc 1.94 0 Td (I )Tj EMC /Suspect <>BDC 0.239 g 0.561 0 Td (2 )Tj EMC /Suspect <>BDC 0.329 g -0.035 Tc 5.8473 0 0 6.2 275.33 315.12 Tm (1.4 )Tj EMC /Suspect <>BDC 0.239 g 0.05 Tc 6.0848 0 0 6 148.66 301.69 Tm (FLOW )Tj EMC /Suspect <>BDC 8.5201 0 0 6 172.17 301.69 Tm (\(lilers/ )Tj EMC ET BT /T1_2 1 Tf 6.6591 0 0 6 200.1 301.69 Tm (sec\) )Tj ET BT /Suspect <>BDC 0.176 g /T1_0 1 Tf 0 Tc 4.8001 0 0 4.8001 118.88 277.69 Tm (1 )Tj EMC /Suspect <>BDC 0.447 0.447 0.443 rg /T1_2 1 Tf 6 0 0 6 127.06 275.28 Tm (E)Tj 0.239 g 0.05 Tc 6.0119 0 0 6 131.52 275.28 Tm (XPIRA)Tj 0.447 0.447 0.443 rg 0 Tc 6 0 0 6 150.68 275.28 Tm (T)Tj 0.239 g 0.0194 Tc 0.7 0 Td (ION )Tj EMC ET BT 0.329 g /T1_2 1 Tf 0 Tc 6 0 0 6 170.36 275.28 Tm (} )Tj ET BT /Suspect <>BDC /T1_2 1 Tf 0.0321 Tc 6 0 0 6 181.31 275.28 Tm (NOSE )Tj EMC /Suspect <>BDC 0.0462 Tc 3.52 0 Td (BREATHING )Tj EMC /Suspect <>BDC 0.239 g 0.0349 Tc -12.565 -0.88 Td (INS)Tj 0.447 0.447 0.443 rg 0 Tc 1.765 0 Td (P)Tj 0.239 g 0.0406 Tc 0.715 0 Td (IRATION )Tj EMC /Suspect <>BDC 0.176 g 0 Tc 3.5001 0 0 3.5001 118.52 260.89 Tm (0 )Tj EMC /Suspect <>BDC 0.329 g 0.0345 Tc 6 0 0 6 127.06 258 Tm (EXPIRATION )Tj EMC ET BT /T1_2 1 Tf 0 Tc 6 0 0 6 170.362 258 Tm (} )Tj ET BT /Suspect <>BDC 0.239 g /T1_2 1 Tf -0.0047 Tc 6 0 0 6 180.832 258 Tm (MOUTH )Tj EMC /Suspect <>BDC 0.329 g 0.0362 Tc 4.32 0 Td (BREATHING )Tj EMC ET BT /T1_0 1 Tf 0 Tc 6.4001 0 0 6.4001 118.5 252.25 Tm (o )Tj ET BT /Suspect <>BDC /T1_2 1 Tf 0.05 Tc 6.1332 0 0 6 127.03 252.25 Tm (INSP)Tj 0.553 g 0 Tc 6 0 0 6 142.4 252.25 Tm (I)Tj 0.329 g 0.0187 Tc 0.483 0 Td (RATION )Tj EMC /Suspect <>BDC 0.239 g /C0_0 1 Tf 0 Tc 4.8 0 0 8.16 59.05 235.93 Tm <007E0020>Tj EMC /Suspect <>BDC /T1_2 1 Tf 0.05 Tc 6.1847 0 0 6 107.53 235.93 Tm (AIRWAY )Tj EMC /Suspect <>BDC 0.329 g 6.0995 0 0 6 138.16 235.93 Tm (OPENING )Tj EMC /Suspect <>BDC 0.239 g 0.001 Tc 6 0 0 6 227.87 235.93 Tm (PHARYNX )Tj EMC /Suspect <>BDC -0.035 Tc 10.9747 0 0 11.9 58.89 226.33 Tm ("' )Tj EMC /Suspect <>BDC 0 -0.363 TD ("' )Tj EMC ET BT /T1_0 1 Tf 0 Tc 6.5001 0 0 6.5001 59.03 223.44 Tm (w )Tj ET BT /Suspect <>BDC /C0_0 1 Tf 4.8 0 0 8.16 59.05 214.33 Tm <007E0020>Tj EMC ET BT /T1_0 1 Tf 6.9001 0 0 6.9001 80.08 214.33 Tm (6 )Tj 0.702 g 0.05 Tc 11.5582 0 0 6.9001 92.98 214.33 Tm (-----------------)Tj 0.239 g 7.4258 0 0 4.5001 59.37 206.16 Tm (.J )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 5.4456 0 0 5.8001 59.5 199.44 Tm (>BDC 0 Tc 5.8001 0 0 5.8001 68.09 199.44 Tm (-)Tj EMC /Suspect <>BDC 0.176 g /C0_0 1 Tf 4.8 0 0 7.68 59.05 192.25 Tm <007E0020>Tj EMC /Suspect <>BDC 0.239 g 1.9 0 Td <007E0020>Tj EMC ET BT /T1_2 1 Tf 6.2 0 0 6.2 79.66 192.25 Tm (4 )Tj ET BT /Suspect <>BDC 0.329 g /T1_0 1 Tf 0.05 Tc 5.9598 0 0 5.1 58.98 186.49 Tm (0: )Tj EMC /Suspect <>BDC 0.176 g 7.2092 0 0 5.1 68.5 186.49 Tm ("' )Tj EMC /Suspect <>BDC 0.329 g /T1_3 1 Tf 14.2738 0 0 8.5 58.94 182.65 Tm (;t-)Tj EMC ET BT 0.239 g /T1_0 1 Tf 0 Tc 5.4001 0 0 5.4001 70.51 176.41 Tm (o )Tj 0.0411 Tc 6.4001 0 0 6.4001 58.98 173.05 Tm (a: )Tj 0.05 Tc 7.5681 0 0 6.4001 72.32 173.05 Tm (.. )Tj ET BT /Suspect <>BDC /C0_0 1 Tf 0 Tc 5.28 0 0 7.2 59.05 165.85 Tm <007E0020>Tj EMC /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 7.9171 0 0 14.8 68.1 165.85 Tm (c: )Tj EMC ET BT /T1_2 1 Tf 0 Tc 6.2 0 0 6.2 80.11 165.85 Tm (2 )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.035 Tc 9.2774 0 0 21.7001 59.27 158.65 Tm (.. )Tj EMC ET BT /T1_2 1 Tf 0 Tc 6.7 0 0 6.7 58.94 153.85 Tm (> )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 10.6083 0 0 14.1 112.15 200.89 Tm (\225\225 )Tj EMC /Suspect <>BDC 0.176 g 0.05 Tc 15.0206 0 0 12.3 130.8 203.76 Tm (\225\225\225 )Tj EMC /Suspect <>BDC 0.553 g 0 Tc 4.4001 0 0 4.4001 119 168.25 Tm (0 )Tj EMC /Suspect <>BDC 0.329 g 4.7 0 0 4.7 139.15 155.29 Tm (0 )Tj EMC /Suspect <>BDC 7 0 0 7 147.77 155.29 Tm (Q )Tj EMC /Suspect <>BDC 0.239 g 4.7 0 0 4.7 160.27 155.29 Tm (0 )Tj EMC /Suspect <>BDC /C0_0 1 Tf 10.0267 0 0 5.76 79.68 145.69 Tm <006F007E007E007E007E007E007E007E004D0020>Tj EMC /Suspect <>BDC 0.447 0.447 0.443 rg /T1_0 1 Tf 6.5001 0 0 6.5001 86.33 138.97 Tm (0 )Tj EMC ET BT 0.239 g /T1_0 1 Tf 6.5001 0 0 6.5001 99.3172 138.97 Tm (2 )Tj 0.329 g 1.537 0 Td (.)Tj 0.176 g 0.089 0 Td (4 )Tj 0.239 g 6.4001 0 0 6.4001 122.32 138.97 Tm [(6 )-1050(6 )]TJ ET BT /Suspect <>BDC 0.329 g /T1_2 1 Tf -0.035 Tc 5.8473 0 0 6.2 144.29 138.97 Tm (1.0 )Tj EMC /Suspect <>BDC /T1_0 1 Tf 6.0618 0 0 6.4001 155.31 138.97 Tm (1.2 )Tj EMC /Suspect <>BDC 0.239 g /T1_2 1 Tf 0.05 Tc 6.7017 0 0 6.2 166.83 138.97 Tm (14 )Tj EMC /Suspect <>BDC 0.553 g /C0_0 1 Tf 0 Tc 3.36 0 0 5.28 205.93 213.85 Tm <002D>Tj 0.447 0.447 0.443 rg 1.429 0 Td <002D002D>Tj 0.553 g 2.88 0 0 5.28 218.89 213.85 Tm <002D>Tj 0.239 g 3.36 0 0 5.28 223.68 213.85 Tm <007E>Tj 0.447 0.447 0.443 rg 3.6 0 0 5.28 228 213.85 Tm <002D002D>Tj 0.176 g 2.88 0 0 5.28 234.73 213.85 Tm <002E>Tj 0.447 0.447 0.443 rg 3.36 0 0 5.28 236.65 213.85 Tm <002D>Tj 0.239 g 0.997 0 Td <002E002D002E00B7>Tj 0.553 g 4.432 0 Td <002D>Tj 0.239 g 1.426 0 Td <007E0020>Tj EMC /Suspect <>BDC 0.553 g /T1_0 1 Tf 0.05 Tc 10.8643 0 0 9.2 264.35 213.85 Tm (----)Tj EMC /Suspect <>BDC 0.447 0.447 0.443 rg /T1_2 1 Tf 0 Tc 13.8 0 0 13.8 229.25 197.52 Tm (" )Tj EMC /Suspect <>BDC 0.553 g 3.8001 0 0 3.8001 249.56 180.25 Tm (0 )Tj EMC /Suspect <>BDC 0.239 g /T1_0 1 Tf 6.4001 0 0 6.4001 199.62 138.97 Tm (0 )Tj EMC ET BT 0.329 g /T1_0 1 Tf 0.05 Tc 6.9713 0 0 6.4001 210.1 138.97 Tm (.2 )Tj -0.0324 Tc 6.4001 0 0 6.4001 221.15 138.97 Tm (.4 )Tj 0.553 g 0 Tc 1.65 0 Td (.)Tj 0.239 g 0.308 0 Td [(6 )-1120(8 )]TJ ET BT /Suspect <>BDC /T1_0 1 Tf -0.0268 Tc 6.4001 0 0 6.4001 256.581 138.97 Tm (1.0 )Tj EMC /Suspect <>BDC 0 Tc 1.753 0 Td (I )Tj EMC ET BT /T1_0 1 Tf 6.4001 0 0 6.4001 270.6804 138.97 Tm (2 )Tj ET BT /Suspect <>BDC 0.329 g /T1_2 1 Tf -0.035 Tc 5.4574 0 0 6.2 279.67 138.97 Tm (1.4 )Tj EMC /Suspect <>BDC 0.239 g /T1_0 1 Tf 0.05 Tc 5.9598 0 0 5.1 58.98 145.21 Tm (0: )Tj EMC /Suspect <>BDC 0 Tc 6.2 0 0 6.2 59.03 140.89 Tm (w )Tj EMC /Suspect <>BDC 0.329 g 0.05 Tc 5.9143 0 0 5.1 58.84 136.09 Tm (1-)Tj EMC /Suspect <>BDC 0.239 g /T1_2 1 Tf -0.035 Tc 10.3082 0 0 21.7001 58.76 132.25 Tm (.. )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 4.32 0 0 4.8 59.53 126.48 Tm <007E0020>Tj EMC /Suspect <>BDC /T1_2 1 Tf 0.0108 Tc 6 0 0 6 143.38 126.96 Tm (FLOW )Tj EMC /Suspect <>BDC 0.329 g 0.05 Tc 7.4285 0 0 6 163.55 126.96 Tm (\(liters )Tj EMC /Suspect <>BDC 0.239 g /T1_3 1 Tf 0 Tc 5.9001 0 0 5.9001 185.66 126.96 Tm (I )Tj EMC ET BT 0.329 g /T1_2 1 Tf 0.05 Tc 6.4213 0 0 6 190.51 126.96 Tm (sec\) )Tj 0.239 g /T1_0 1 Tf -0.0146 Tc 8.2 0 0 8.2 58.53 111.12 Tm (Fig. )Tj -0.0107 Tc 1.866 0 Td (3. )Tj 0.0313 Tc 1.76 0 Td (Inspiratory )Tj 0.045 Tc 4.915 0 Td (and )Tj 0.0273 Tc 1.755 0 Td (expiratory )Tj 0 Tc 4.568 0 Td (T )Tj 0.045 Tc 0.935 0 Td (and )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 7.4288 0 0 8.2 203.01 111.12 Tm (PH)Tj 0 Tc 5.2 0 0 5.2 212.61 109.2 Tm (2)Tj 8.2 0 0 8.2 215.92 111.12 Tm (o )Tj EMC ET BT /T1_1 1 Tf -0.035 Tc 8.5023 0 0 8.7 222.67 111.12 Tm (versus )Tj /T1_0 1 Tf 0.0182 Tc 8.2 0 0 8.2 244.81 111.12 Tm (peak )Tj 0.329 g -0.0317 Tc 2.212 0 Td (flow )Tj 0.239 g 0.05 Tc 8.222 0 0 8.2 279.76 111.12 Tm (at )Tj 0.0058 Tc 8.2 0 0 8.2 58.54 102 Tm (the )Tj 0.0089 Tc 1.456 0 Td (airway )Tj 0.045 Tc 2.985 0 Td (and )Tj 0.0311 Tc 1.826 0 Td (pharynx )Tj 0.05 Tc 9.4598 0 0 8.2 140.07 102 Tm (of )Tj 0 Tc 8.2 0 0 8.2 149.2 102 Tm (a )Tj 0.02 Tc 0.77 0 Td (normal )Tj 0.0205 Tc 3.148 0 Td (subject )Tj 0.03 Tc 3.166 0 Td (during )Tj 0.0148 Tc 2.994 0 Td (nose )Tj 0.045 Tc 2.099 0 Td (and )Tj 0.0358 Tc 1.822 0 Td (mouth )Tj 0.0198 Tc -25.05 -1.054 Td (breathing )Tj 0.05 Tc 8.9033 0 0 8.2 93.04 93.36 Tm (of )Tj 0.0366 Tc 8.2 0 0 8.2 102.71 93.36 Tm (hot )Tj 0.0091 Tc 1.689 0 Td (air: )Tj -0.0296 Tc 1.706 0 Td (A. )Tj 0.05 Tc 8.4933 0 0 8.2 141.04 93.36 Tm (Gas )Tj 0.0204 Tc 8.2 0 0 8.2 157.42 93.36 Tm (temperature; )Tj -0.035 Tc 7.2609 0 0 8.2 203.97 93.36 Tm (B. )Tj 0.0212 Tc 8.2 0 0 8.2 213.57 93.36 Tm (Water )Tj 0.0313 Tc 2.87 0 Td (vapour )Tj 0.0253 Tc 3.282 0 Td (partial )Tj 0.176 g 0.0106 Tc -25.112 -1.111 Td (pressure )Tj 0.239 g 0.016 Tc 3.674 0 Td (\(equilibrium )Tj 0.0173 Tc 5.513 0 Td (water )Tj 0.043 Tc (vapour )Tj 0.019 Tc 5.856 0 Td (pressure )Tj 0.05 Tc 8.8544 0 0 8.2 212.07 84.25 Tm (at )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0039 Tc 8.2 0 0 8.2 221.19 84.25 Tm (37"C )Tj EMC ET BT /T1_0 1 Tf 0.0121 Tc 8.2 0 0 8.2 240.3616 84.25 Tm (shown )Tj 0.0047 Tc 3.001 0 Td (by )Tj 0.0351 Tc 1.343 0 Td (the )Tj 0.0088 Tc -26.583 -1.113 Td (dashed )Tj -0.0149 Tc 3.221 0 Td (line\). )Tj /T1_1 1 Tf 0.0094 Tc 9.8 0 0 9.8 311.62 731.29 Tm (Inspiring )Tj 0.0201 Tc 4.098 0 Td (ambient )Tj 0.0092 Tc 3.673 0 Td (air )Tj /T1_0 1 Tf 0.0097 Tc 10.4 0 0 10.4 321.07 716.41 Tm (Flow-averaged )Tj -0.0125 Tc 6.873 0 Td (gas )Tj 0.0225 Tc 2.075 0 Td (and )Tj 0.0074 Tc 2.27 0 Td (mucosal )Tj 0.0149 Tc 4.245 0 Td (temperatures, )Tj 0.012 Tc -16.383 -1.015 Td (water )Tj 0.0274 Tc 2.63 0 Td (vapour )Tj 0.176 g 0.015 Tc 3.281 0 Td (partial )Tj 0.239 g -0.0021 Tc 3.046 0 Td (pressure, )Tj 0.0456 Tc 3.957 0 Td (and )Tj 0.0184 Tc 1.948 0 Td (relat)Tj 0.071 g 0 Tc 1.885 0 Td (i)Tj 0.239 g -0.0144 Tc 0.237 0 Td (ve )Tj 0.176 g 0.0126 Tc 1.293 0 Td (humidity )Tj 0.239 g -0.0147 Tc -18.277 -1.063 Td (were )Tj 0.0086 Tc 2.53 0 Td (obtained. )Tj 0.176 g -0.0085 Tc 4.437 0 Td (When )Tj 0.239 g 0.02 Tc 3.051 0 Td (breathing )Tj 0.0349 Tc 4.512 0 Td (ambient )Tj 0.0329 Tc 4.015 0 Td (air )Tj -0.035 Tc 10.3282 0 0 10.4 522.6 694.8 Tm (\(figs )Tj -0.013 Tc 10.4 0 0 10.4 311.48 683.76 Tm (4A, )Tj 0.176 g -0.008 Tc 1.892 0 Td (4B, )Tj -0.0087 Tc 1.846 0 Td (4C\), )Tj 0.239 g -0.0023 Tc 2.216 0 Td (there )Tj -0.0147 Tc 2.448 0 Td (were )Tj 0.0187 Tc 2.354 0 Td (no )Tj 0.0342 Tc 1.468 0 Td (outstanding )Tj -0.009 Tc 5.4 0 Td (differences )Tj -0.0069 Tc -17.62 -1.014 Td (between )Tj 0.0143 Tc 3.735 0 Td (the )Tj 0.0162 Tc 1.71 0 Td (normal )Tj 0.0456 Tc 3.313 0 Td (and )Tj 0.05 Tc 10.7486 0 0 10.4 423.25 673.21 Tm (CF )Tj 0.0023 Tc 10.4 0 0 10.4 441.45 673.21 Tm (subjects, )Tj 0.0183 Tc 3.937 0 Td (whether )Tj 0.0333 Tc 3.73 0 Td (data )Tj -0.0147 Tc -20.161 -1.062 Td (were )Tj 0.329 g 0.0157 Tc 2.213 0 Td (take)Tj 0.176 g 0 Tc 1.756 0 Td (n )Tj 0.239 g 0.05 Tc 10.7518 0 0 10.4 360.85 662.17 Tm (at )Tj 0.0143 Tc 10.4 0 0 10.4 372.45 662.17 Tm (the )Tj 0.0093 Tc 1.574 0 Td (pharynx )Tj 0.05 Tc 11.1292 0 0 10.4 426.61 662.17 Tm (or )Tj 0.0125 Tc 10.4 0 0 10.4 439.09 662.17 Tm (airway )Tj 0.0083 Tc 3.139 0 Td (opening, )Tj 0.0244 Tc 3.831 0 Td (during )Tj 0.0128 Tc -19.245 -1.062 Td (inspiration )Tj 0.05 Tc 10.5727 0 0 10.4 360.38 651.12 Tm (or )Tj 0.0104 Tc 10.4 0 0 10.4 372.37 651.12 Tm (expiration, )Tj 0.0282 Tc 4.715 0 Td (through )Tj 0.0373 Tc 3.554 0 Td (the )Tj 0.0212 Tc 1.571 0 Td (nose )Tj 0.05 Tc 10.5727 0 0 10.4 497.18 651.12 Tm (or )Tj 0.0216 Tc 10.4 0 0 10.4 509.26 651.12 Tm (mouth. )Tj -0.0037 Tc -19.022 -1.061 Td (These )Tj -0.0195 Tc 2.72 0 Td (figures, )Tj 0.176 g -0.0124 Tc 3.288 0 Td (however, )Tj 0.239 g 0.0137 Tc 3.962 0 Td (illustrate )Tj -0.009 Tc 3.968 0 Td (differences )Tj 0.0008 Tc 4.718 0 Td (between )Tj -0.0088 Tc -18.604 -1.015 Td (the )Tj 0.0118 Tc 1.61 0 Td (inspiratory )Tj 0.0456 Tc 4.844 0 Td (and )Tj 0.0178 Tc 1.892 0 Td (expiratory )Tj 0.0106 Tc 4.663 0 Td (gas )Tj 0.0217 Tc 1.707 0 Td (conditions )Tj 0.05 Tc 10.7518 0 0 10.4 514.45 629.53 Tm (at )Tj 0.0143 Tc 10.4 0 0 10.4 527.01 629.53 Tm (the )Tj 0.0032 Tc -20.731 -1.062 Td (airway )Tj 0.0129 Tc 3.186 0 Td (opening )Tj 0.0225 Tc 3.691 0 Td (and )Tj 0.0295 Tc 1.938 0 Td (at )Tj 0.0143 Tc 1.208 0 Td (the )Tj 0.0185 Tc 1.666 0 Td (pharynx. )Tj 0.0244 Tc 4.14 0 Td (\(Note )Tj 0.0402 Tc 2.824 0 Td (that )Tj 0.0143 Tc 2.077 0 Td (the )Tj -0.0048 Tc -20.722 -1.062 Td (vertical )Tj 0.0174 Tc 3.372 0 Td (bars )Tj 0.0131 Tc 2.108 0 Td (span )Tj 0.0143 Tc 2.273 0 Td (the )Tj 0.176 g 0.0222 Tc 1.617 0 Td (range )Tj 0.239 g 0.05 Tc 11.1292 0 0 10.4 436.69 607.44 Tm (of )Tj -0.0084 Tc 10.4 0 0 10.4 449.65 607.44 Tm (all )Tj 0.05 Tc 10.6431 0 0 10.4 463.58 607.44 Tm (data )Tj 0.0042 Tc 10.4 0 0 10.4 487.22 607.44 Tm (points\). )Tj 0.0394 Tc 3.451 0 Td (The )Tj 0.0069 Tc -20.36 -1.014 Td (sublingual )Tj 0.0126 Tc 4.581 0 Td (temperature )Tj 0.0101 Tc 5.263 0 Td (ranged )Tj 0.0075 Tc 3.174 0 Td (from )Tj 0.017 Tc 2.354 0 Td (36.5-36.8\260C )Tj 0.0074 Tc 5.4 0 Td (for )Tj 0.0143 Tc -20.761 -1.062 Td (the )Tj 0.176 g 0.0162 Tc 1.525 0 Td (normal )Tj 0.239 g -0.0012 Tc 3.217 0 Td (subjects )Tj 0.0456 Tc 3.465 0 Td (and )Tj -0.0079 Tc 1.799 0 Td (from )Tj -0.0172 Tc 2.262 0 Td (36.3)Tj 0.553 g 0 Tc 1.708 0 Td (-)Tj 0.239 g -0.0018 Tc 0.6 0 Td (36.9\260C )Tj 0.0074 Tc 3.046 0 Td (for )Tj -0.0088 Tc 1.532 0 Td (the )Tj 0.05 Tc 11.1325 0 0 10.4 525.96 585.85 Tm (CF )Tj -0.0034 Tc 10.4 0 0 10.4 311.37 574.8 Tm (subjects. )Tj 0.0222 Tc 0.982 -1.015 Td (At )Tj -0.0088 Tc 1.337 0 Td (the )Tj 0.0119 Tc 1.482 0 Td (pharynx, )Tj 0.0143 Tc 3.872 0 Td (the )Tj 0.0172 Tc 1.523 0 Td (temperature )Tj -0.0078 Tc 5.209 0 Td (difference )Tj -0.0069 Tc 4.257 0 Td (between )Tj 0.004 Tc -18.656 -1.061 Td (inspired )Tj 0.0225 Tc 3.921 0 Td (and )Tj -0.0037 Tc 2.169 0 Td (expired )Tj 0.0106 Tc 3.602 0 Td (gas )Tj -0.0037 Tc 1.985 0 Td (is )Tj 0.05 Tc 10.5607 0 0 10.4 446.29 553.21 Tm (about )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0098 Tc 10.4 0 0 10.4 478.04 553.21 Tm (4\260C )Tj EMC ET BT 0.176 g /T1_0 1 Tf 0.0074 Tc 10.4 0 0 10.4 501.48 553.21 Tm (for )Tj 0.0058 Tc 1.857 0 Td (nose )Tj 0.239 g 0.02 Tc -20.121 -1.062 Td (breathing )Tj 0.0225 Tc 4.373 0 Td (and )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0087 Tc 10.4 0 0 10.4 378.136 542.1652 Tm (7\260C )Tj EMC ET BT /T1_0 1 Tf 0.0074 Tc 10.4 0 0 10.4 399.248 542.1652 Tm (for )Tj 0.0434 Tc 1.671 0 Td (mouth )Tj 0.0156 Tc 3.234 0 Td (breathing. )Tj -0.0138 Tc 4.751 0 Td (Also, )Tj 0.0143 Tc 2.63 0 Td (the )Tj 0.0172 Tc -20.723 -1.015 Td (temperature )Tj 0.05 Tc 11.1292 0 0 10.4 370.45 531.61 Tm (of )Tj 0.004 Tc 10.4 0 0 10.4 386.79 531.61 Tm (inspired )Tj 0.0106 Tc 3.969 0 Td (gas )Tj 0.176 g 0.0095 Tc 2.077 0 Td (increased )Tj 0.239 g -0.0009 Tc 4.614 0 Td (only )Tj /T1_1 1 Tf -0.035 Tc 12.6 0 0 14.9 524.2 531.61 Tm (soc )Tj /T1_0 1 Tf 0.0205 Tc 10.4 0 0 10.4 311.49 520.56 Tm (through )Tj 0.0143 Tc 3.785 0 Td (the )Tj 0.0122 Tc 1.747 0 Td (oral )Tj 0.0174 Tc 2.181 0 Td (path, )Tj 0.05 Tc 10.531 0 0 10.4 418.57 520.56 Tm (but )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0085 Tc 10.4 0 0 10.4 438.12 520.56 Tm (9\260C )Tj EMC ET BT /T1_0 1 Tf 0.0359 Tc 10.4 0 0 10.4 459.8144 520.56 Tm (through )Tj 0.0143 Tc 3.831 0 Td (the )Tj 0.0071 Tc 1.756 0 Td (nasal )Tj 0.0174 Tc -19.843 -1.107 Td (path. )Tj 0.024 Tc 2.532 0 Td (Furthermore, )Tj -0.0088 Tc 5.956 0 Td (the )Tj 0.004 Tc 1.608 0 Td (expired )Tj 0.0106 Tc 3.463 0 Td (gas )Tj 0.0172 Tc 1.806 0 Td (temperature )Tj ET BT /Suspect <>BDC /C0_0 1 Tf 0 Tc 4.16 0 0 7.68 527.53 509.05 Tm <007E006F00720020>Tj EMC ET BT /T1_0 1 Tf -0.0096 Tc 10.4 0 0 10.4 311.51 498.49 Tm (nose )Tj 0.0142 Tc 2.171 0 Td (breathing )Tj -0.035 Tc 9.3682 0 0 10.4 377.68 498.49 Tm (is )Tj -0.0327 Tc 10.4 0 0 10.4 386.79 498.49 Tm (less )Tj 0.0274 Tc 1.76 0 Td (than )Tj 0.0288 Tc 2.127 0 Td (body )Tj 0.0218 Tc 2.396 0 Td (temperature )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0003 Tc 10.4 0 0 10.4 507.2428 498.49 Tm (\(sublin\255)Tj EMC ET BT /T1_0 1 Tf -0.0019 Tc 10.4 0 0 10.4 311.4316 487.4452 Tm (gual\) )Tj -0.0212 Tc 2.548 0 Td (by )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0421 Tc 10.4 0 0 10.4 354.1756 487.4452 Tm (I-2\260C, )Tj EMC ET BT /T1_0 1 Tf 0.0014 Tc 10.4 0 0 10.4 386.8732 487.4452 Tm (whereas )Tj 0.0074 Tc 3.774 0 Td (for )Tj 0.0318 Tc 1.671 0 Td (mouth )Tj 0.176 g 0.02 Tc 3.234 0 Td (breathing )Tj 0.239 g 0.016 Tc 4.375 0 Td (it )Tj -0.035 Tc 9.3682 0 0 10.4 533.68 487.44 Tm (is )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 10.4223 0 0 10.4 310.98 476.89 Tm (2-3\260C )Tj EMC ET BT /T1_0 1 Tf -0.0293 Tc 10.4 0 0 10.4 345.99 476.89 Tm (less. )Tj 0.05 Tc 10.762 0 0 10.4 371.47 476.89 Tm (For )Tj 0.0263 Tc 10.4 0 0 10.4 395.53 476.89 Tm (both )Tj 0.0096 Tc 2.615 0 Td (subject )Tj 0.0225 Tc 3.652 0 Td (groups, )Tj 0.0143 Tc 3.883 0 Td (the )Tj -0.0177 Tc 2.033 0 Td (wall )Tj 0.0172 Tc -20.263 -1.062 Td (temperature )Tj 0.0004 Tc 5.355 0 Td (varied )Tj -0.0138 Tc 2.909 0 Td (negligibly )Tj 0.05 Tc 10.7518 0 0 10.4 442.45 465.84 Tm (at )Tj 0.0143 Tc 10.4 0 0 10.4 455.01 465.84 Tm (the )Tj 0.017 Tc 1.666 0 Td (pharynx )Tj 0.0244 Tc 3.773 0 Td (during )Tj 0.0143 Tc -19.239 -1.061 Td (the )Tj 0.176 g 0.02 Tc 1.85 0 Td (breathing )Tj 0.239 g -0.0241 Tc 4.466 0 Td (cycle. )Tj 0.176 g 0.0163 Tc 2.862 0 Td (The )Tj 0.239 g -0.0331 Tc 2.223 0 Td (wall )Tj 0.0218 Tc 2.306 0 Td (temperature )Tj 0.05 Tc 10.7518 0 0 10.4 512.05 454.81 Tm (at )Tj 0.0143 Tc 10.4 0 0 10.4 527.01 454.81 Tm (the )Tj 0.0247 Tc -20.764 -1.062 Td (pharynx )Tj -0.035 Tc 10.1489 0 0 10.4 350.8 443.76 Tm (is )Tj -0.0111 Tc 10.4 0 0 10.4 361.83 443.76 Tm (lower )Tj 0.176 g 0.0274 Tc 2.637 0 Td (than )Tj 0.239 g 0.0143 Tc 2.262 0 Td (the )Tj -0.0081 Tc 1.656 0 Td (local )Tj 0.0106 Tc 2.354 0 Td (gas )Tj 0.0218 Tc 1.76 0 Td (temperature )Tj 0.0358 Tc 5.393 0 Td (on )Tj 0.0104 Tc -20.955 -1.014 Td (expiration. )Tj 0.05 Tc 10.4358 0 0 10.4 360.91 433.21 Tm (For )Tj -0.0096 Tc 10.4 0 0 10.4 380.15 433.21 Tm (nose )Tj 0.05 Tc 10.5727 0 0 10.4 402.14 433.21 Tm (or )Tj 0.0203 Tc 10.4 0 0 10.4 414.7 433.21 Tm (mouth )Tj 0.02 Tc 3.049 0 Td (breathing )Tj 0.0143 Tc 4.242 0 Td (the )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0058 Tc 10.4 0 0 10.4 506.844 433.21 Tm (temper\255)Tj EMC ET BT 0.176 g /T1_0 1 Tf 0.0345 Tc 10.4 0 0 10.4 310.9288 422.1652 Tm (ature )Tj 0.239 g -0.0078 Tc 2.493 0 Td (difference )Tj -0.0146 Tc 4.395 0 Td (between )Tj 0.004 Tc 3.637 0 Td (inspired )Tj 0.0456 Tc 3.644 0 Td (and )Tj -0.0037 Tc 1.938 0 Td (expired )Tj -0.0125 Tc 3.417 0 Td (gas )Tj 0.05 Tc 10.7518 0 0 10.4 531.73 422.16 Tm (at )Tj 0.0143 Tc 10.4 0 0 10.4 311.49 411.12 Tm (the )Tj 0.0032 Tc 1.838 0 Td (airway )Tj 0.0129 Tc 3.37 0 Td (opening )Tj -0.035 Tc 10.1489 0 0 10.4 406 411.12 Tm (is )Tj 0.0362 Tc 10.4 0 0 10.4 418.93 411.12 Tm (about )Tj ET BT /Suspect <>BDC 0.176 g /T1_0 1 Tf 0.0125 Tc 10.4 0 0 10.4 451.6068 411.12 Tm (I0)Tj 0.447 0.447 0.443 rg 0 Tc 0.872 0 Td (-)Tj 0.239 g -0.0301 Tc 0.623 0 Td (11\260C. )Tj EMC ET BT 0.176 g /T1_0 1 Tf 0.0394 Tc 10.4 0 0 10.4 496.2228 411.12 Tm (The )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 10.4 0 0 10.4 519.3004 411.12 Tm (H)Tj 6.4001 0 0 6.4001 527.96 408.72 Tm (2)Tj 10.5 0 0 10.5 532.21 411.12 Tm (0 )Tj EMC ET BT 0.239 g /T1_0 1 Tf 0.015 Tc 10.4 0 0 10.4 311.54 400.09 Tm (partial )Tj 0.0069 Tc 3.138 0 Td (pressure )Tj -0.0071 Tc 3.814 0 Td (shows )Tj -0.0136 Tc 2.959 0 Td (differences )Tj 0.0175 Tc 4.8 0 Td (corresponding )Tj 0.01 Tc 6.422 0 Td (to )Tj 0.176 g 0.0041 Tc -21.138 -1.062 Td (those )Tj 0.239 g 0.05 Tc 11.1292 0 0 10.4 337.33 389.05 Tm (of )Tj 0.0143 Tc 10.4 0 0 10.4 349.41 389.05 Tm (the )Tj 0.0106 Tc 1.563 0 Td (gas )Tj 0.0139 Tc 1.667 0 Td (temperature. )Tj 0.0369 Tc -5.956 -1.062 Td (During )Tj 0.0099 Tc 3.319 0 Td (inspiration, )Tj -0.0088 Tc 5.083 0 Td (the )Tj 0.176 g 0.001 Tc 1.617 0 Td (relative )Tj 0.239 g 0.0192 Tc 3.323 0 Td (humidity )Tj 0.0287 Tc 4.097 0 Td (\(RH\), )Tj 0.05 Tc 11.3843 0 0 10.4 531.24 378 Tm (at )Tj 0.0143 Tc 10.4 0 0 10.4 311.49 366.97 Tm (the )Tj 0.0324 Tc 1.666 0 Td (pharynx )Tj -0.035 Tc 9.3682 0 0 10.4 370.48 366.97 Tm (is )Tj 0.0071 Tc 10.4 0 0 10.4 382.07 366.97 Tm (higher )Tj 0 Tc 3.082 0 Td (\( )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0476 Tc 10.4 0 0 10.4 418.9276 366.97 Tm (--95%\) )Tj EMC ET BT 0.176 g /T1_0 1 Tf 0.0074 Tc 10.4 0 0 10.4 456.3676 366.97 Tm (for )Tj 0.239 g -0.0096 Tc 1.764 0 Td (nose )Tj 0.0142 Tc 2.356 0 Td (breathing )Tj 0.0274 Tc -18.05 -1.062 Td (than )Tj 0.0074 Tc 2.068 0 Td (for )Tj 0.0318 Tc 1.487 0 Td (mouth )Tj 0.0142 Tc 3.003 0 Td (breathing )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 11.4959 0 0 10.4 422.74 355.93 Tm (\("' )Tj EMC ET BT /T1_0 1 Tf 0.0247 Tc 10.4 0 0 10.4 436.21 355.93 Tm (75%\) )Tj 0.0135 Tc 2.494 0 Td (This )Tj -0.035 Tc 9.3682 0 0 10.4 484.24 355.93 Tm (is )Tj 0.176 g -0.0153 Tc 10.4 0 0 10.4 493.43 355.93 Tm (reflected )Tj 0.239 g 0.0238 Tc 3.638 0 Td (in )Tj 0.0263 Tc -21.129 -1.015 Td (both )Tj 0.0143 Tc 2.119 0 Td (the )Tj 0.176 g 0 Tc 1.471 0 Td (T )Tj 0.239 g 0.0225 Tc 0.921 0 Td (and )Tj 0.176 g /T1_2 1 Tf -0.0187 Tc 9 0 0 9 376.6 345.37 Tm (PH)Tj /T1_0 1 Tf 0 Tc 6.9001 0 0 6.9001 388.76 342.97 Tm (2)Tj 10.4 0 0 10.4 392.54 345.37 Tm (o )Tj 0.239 g 0.05 Tc 11.1292 0 0 10.4 400.69 345.37 Tm (of )Tj 0.329 g 0.0143 Tc 10.4 0 0 10.4 412.29 345.37 Tm (the )Tj 0.239 g 0.0006 Tc 1.471 0 Td (gas. )Tj 0.176 g 0.0369 Tc 1.85 0 Td (During )Tj 0.239 g 0.0137 Tc 3.225 0 Td (expiration )Tj -0.0088 Tc 4.485 0 Td (the )Tj 0.176 g 0.0451 Tc -20.725 -1.062 Td (RH )Tj 0.239 g -0.0016 Tc 1.849 0 Td (values )Tj 0.0422 Tc 2.853 0 Td (are )Tj 0.0124 Tc 1.615 0 Td (approximately )Tj 0.0373 Tc 6.285 0 Td (the )Tj 0.0167 Tc 1.604 0 Td (same )Tj 0.0074 Tc 2.449 0 Td (for )Tj -0.0096 Tc 1.58 0 Td (nose )Tj 0.0456 Tc 2.16 0 Td (and )Tj 0.0318 Tc -20.438 -1.062 Td (mouth )Tj 0.176 g 0.02 Tc 3.141 0 Td (breathing )Tj 0.239 g 0.05 Tc 10.7518 0 0 10.4 388.69 323.28 Tm (at )Tj 0.0263 Tc 10.4 0 0 10.4 401.29 323.28 Tm (both )Tj 0.0143 Tc 2.304 0 Td (the )Tj 0.0247 Tc 1.666 0 Td (pharynx )Tj 0 Tc 3.863 0 Td (\( )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 10.8457 0 0 10.4 486.99 323.28 Tm ("'95%\) )Tj EMC ET BT /T1_0 1 Tf 0.0456 Tc 10.4 0 0 10.4 523.57 323.28 Tm (and )Tj 0.0143 Tc -20.392 -1.061 Td (the )Tj 0.0032 Tc 1.562 0 Td (airway )Tj 0.0129 Tc 3.093 0 Td (opening )Tj 0 Tc 3.598 0 Td (\( )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0288 Tc 10.4 0 0 10.4 402.1292 312.2456 Tm (--90%\). )Tj EMC ET BT /T1_1 1 Tf 0.0155 Tc 9.8 0 0 9.8 311.14 287.28 Tm (Inspiring )Tj 0.05 Tc 9.8808 0 0 9.8 351.31 287.28 Tm (hot )Tj 0.176 g 0.0092 Tc 9.8 0 0 9.8 368.1 287.28 Tm (air )Tj /T1_0 1 Tf 0.0059 Tc 10.4 0 0 10.4 321.55 272.41 Tm (Flow-averaged )Tj 0.239 g 0.0333 Tc 6.272 0 Td (data )Tj 0.176 g 0.0305 Tc 2.029 0 Td (for )Tj 0.239 g 0.0143 Tc 1.486 0 Td (the )Tj 0.0167 Tc 1.465 0 Td (same )Tj 0.0054 Tc 2.308 0 Td (subjects )Tj 0.0142 Tc 3.523 0 Td (breathing )Tj 0.176 g 0.0327 Tc -18.094 -1.016 Td (hot )Tj 0.239 g 0.0329 Tc 1.744 0 Td (air )Tj 0.0191 Tc 1.431 0 Td (are )Tj -0.0003 Tc 1.658 0 Td (shown )Tj 0.176 g -0.0224 Tc 3.006 0 Td (in )Tj 0.239 g -0.0195 Tc 1.151 0 Td (figures )Tj -0.0313 Tc 3.086 0 Td (SA, )Tj -0.035 Tc 10.0657 0 0 10.4 455.86 261.84 Tm (5B )Tj 0.0225 Tc 10.4 0 0 10.4 471.25 261.84 Tm (and )Tj -0.035 Tc 10.2455 0 0 10.4 491.38 261.84 Tm (5C. )Tj 0.05 Tc 10.762 0 0 10.4 509.71 261.84 Tm (For )Tj -0.0084 Tc 10.4 0 0 10.4 529.33 261.84 Tm (all )Tj 0.0023 Tc -21.004 -1.062 Td (subjects, )Tj -0.0037 Tc 4.019 0 Td (expired )Tj 0.0106 Tc 3.51 0 Td (gas )Tj 0.176 g -0.0132 Tc 1.854 0 Td (was )Tj -0.004 Tc 2.124 0 Td (usually )Tj 0.239 g -0.002 Tc 3.414 0 Td (within )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 10.4 0 0 10.4 499.586 250.7952 Tm (l)Tj 0.447 0.447 0.443 rg 0.366 0 Td (-)Tj 0.239 g -0.0115 Tc 0.56 0 Td (2\260C )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 11.1292 0 0 10.4 530.77 250.8 Tm (of )Tj 0.176 g 0.0135 Tc 10.4 0 0 10.4 311.05 239.76 Tm (body )Tj 0.239 g 0.0172 Tc 2.812 0 Td (temperature )Tj 0.0074 Tc 5.714 0 Td (for )Tj 0.0263 Tc 1.997 0 Td (both )Tj 0.016 Tc 2.632 0 Td (pathways )Tj -0.0006 Tc 4.649 0 Td (and )Tj 0.0263 Tc 2.273 0 Td (both )Tj 0.0126 Tc -20.08 -1.061 Td (measurement )Tj 0.176 g -0.0011 Tc 5.947 0 Td (locations. )Tj 0.239 g 0.0001 Tc 4.385 0 Td (Typically, )Tj 0.0143 Tc 4.575 0 Td (the )Tj -0.0023 Tc 1.71 0 Td (wall )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0058 Tc 10.4 0 0 10.4 506.8508 228.7256 Tm (temper\255)Tj EMC ET BT /T1_0 1 Tf 0.0345 Tc 10.4 0 0 10.4 310.9356 217.6808 Tm (ature )Tj 0.05 Tc 10.7518 0 0 10.4 336.37 217.69 Tm (at )Tj -0.0088 Tc 10.4 0 0 10.4 348.45 217.69 Tm (the )Tj 0.017 Tc 1.574 0 Td (pharynx )Tj -0.0031 Tc 3.726 0 Td (averages )Tj 0.0478 Tc 3.831 0 Td (about )Tj ET BT /Suspect <>BDC 0.176 g /T1_0 1 Tf 0 Tc 10.4 0 0 10.4 473.1876 217.69 Tm (l)Tj 0.329 g 0.05 Tc 10.9091 0 0 10.4 476.51 217.69 Tm (-2\260C )Tj EMC ET BT 0.239 g /T1_0 1 Tf -0.0327 Tc 10.4 0 0 10.4 501.99 217.69 Tm (less )Tj 0.0274 Tc 1.76 0 Td (than )Tj 0.0143 Tc -20.123 -1.015 Td (the )Tj 0.176 g -0.0081 Tc 1.84 0 Td (local )Tj 0.239 g -0.0037 Tc 2.49 0 Td (expired )Tj -0.0125 Tc 3.556 0 Td (gas )Tj 0.0139 Tc 1.898 0 Td (temperature. )Tj 0.176 g -0.035 Tc 9.9514 0 0 10.4 473.24 207.13 Tm (By )Tj 0.239 g 0.0143 Tc 10.4 0 0 10.4 491.01 207.13 Tm (the )Tj 0.0038 Tc 1.792 0 Td (end )Tj 0.05 Tc 11.1292 0 0 10.4 530.77 207.13 Tm (of )Tj 0.176 g 0.0141 Tc 10.4 0 0 10.4 310.95 196.09 Tm (inspiration, )Tj 0.239 g -0.0088 Tc 5.498 0 Td (the )Tj -0.0023 Tc 1.94 0 Td (wall )Tj 0.0218 Tc 2.49 0 Td (temperature )Tj 0.05 Tc 10.7518 0 0 10.4 473.65 196.09 Tm (at )Tj 0.0143 Tc 10.4 0 0 10.4 490.05 196.09 Tm (the )Tj 0.0125 Tc 1.977 0 Td (airway )Tj 0.0016 Tc -19.199 -1.062 Td (openings )Tj -0.0037 Tc 3.924 0 Td (is )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 10.4078 0 0 10.4 361.4 185.05 Tm (4-8\260C )Tj EMC ET BT /T1_0 1 Tf -0.0173 Tc 10.4 0 0 10.4 390.63 185.05 Tm (less )Tj 0.176 g 0.0274 Tc 1.76 0 Td (than )Tj 0.239 g 0.004 Tc 2.117 0 Td (inspired )Tj -0.0125 Tc 3.6 0 Td (gas )Tj 0.0139 Tc 1.621 0 Td (temperature. )Tj ET BT /Suspect <>BDC 0.176 g /T1_0 1 Tf 0.0002 Tc 10.4 0 0 10.4 310.9348 174.0052 Tm (On )Tj EMC ET BT 0.239 g /T1_0 1 Tf 0.0036 Tc 10.4 0 0 10.4 326.2852 174.0052 Tm (average, )Tj -0.0047 Tc 3.654 0 Td (these )Tj -0.0331 Tc 2.263 0 Td (wall )Tj 0.018 Tc 1.937 0 Td (temperatures )Tj 0.176 g 0.0191 Tc 5.577 0 Td (are )Tj 0.239 g -0.0021 Tc 1.533 0 Td (higher )Tj 0.05 Tc 11.0464 0 0 10.4 510.6 174.01 Tm (forCF )Tj -0.0012 Tc 10.4 0 0 10.4 310.89 162.97 Tm (subjects )Tj 0.0428 Tc 3.473 0 Td (than )Tj 0.0074 Tc 2.068 0 Td (for )Tj 0.0162 Tc 1.487 0 Td (normal )Tj -0.0034 Tc 3.171 0 Td (subjects. )Tj 0.05 Tc 10.583 0 0 10.4 455.98 162.97 Tm (At )Tj -0.0088 Tc 10.4 0 0 10.4 469.89 162.97 Tm (the )Tj 0.0119 Tc 1.482 0 Td (pharynx, )Tj 0.0106 Tc 3.866 0 Td (gas )Tj 0.004 Tc -20.631 -1.015 Td (inspired )Tj 0.176 g 0.0205 Tc 3.606 0 Td (through )Tj 0.0143 Tc 3.6 0 Td (the )Tj 0.239 g 0.0058 Tc 1.571 0 Td (nose )Tj -0.0132 Tc 2.169 0 Td (was )Tj 0.016 Tc 1.837 0 Td (cooled )Tj -0.0056 Tc 3.041 0 Td (several )Tj 0.176 g 0.0007 Tc 3.097 0 Td (degrees )Tj 0.239 g -0.0081 Tc -18.913 -1.062 Td (below )Tj 0.176 g 0.0135 Tc 2.723 0 Td (body )Tj 0.239 g 0.0172 Tc 2.35 0 Td (temperature )Tj 0.176 g -0.0224 Tc 5.256 0 Td (in )Tj 0.239 g 0.0263 Tc 1.117 0 Td (both )Tj 0.0014 Tc 2.154 0 Td (sets )Tj 0.05 Tc 11.1292 0 0 10.4 471.25 141.37 Tm (of )Tj -0.0034 Tc 10.4 0 0 10.4 483.21 141.37 Tm (subjects. )Tj 0.0382 Tc 3.789 0 Td (Gas )Tj 0.0166 Tc -20.401 -1.062 Td (entering )Tj 0.0143 Tc 3.654 0 Td (the )Tj 0.0032 Tc 1.469 0 Td (airway )Tj 0.0129 Tc 3.001 0 Td (opening )Tj 0.0191 Tc 3.515 0 Td (may )Tj -0.0082 Tc 2.023 0 Td (differ )Tj -0.0079 Tc 2.444 0 Td (from )Tj -0.0088 Tc 2.27 0 Td (the )Tj 0.176 g 0.0328 Tc 1.471 0 Td (input )Tj 0.239 g 0.0096 Tc -19.852 -1.062 Td (source )Tj 0.05 Tc 11.6856 0 0 10.4 341.17 119.28 Tm (of )Tj -0.0088 Tc 10.4 0 0 10.4 353.73 119.28 Tm (the )Tj 0.05 Tc 10.4873 0 0 10.4 369.11 119.28 Tm (hot )Tj 0.0329 Tc 10.4 0 0 10.4 386.77 119.28 Tm (air )Tj -0.0022 Tc 1.442 0 Td (because )Tj 0.05 Tc 11.1292 0 0 10.4 437.65 119.28 Tm (of )Tj 0.0251 Tc 10.4 0 0 10.4 449.73 119.28 Tm (tubing )Tj 0.176 g -0.0139 Tc 2.948 0 Td (losses, )Tj -0.0022 Tc 2.868 0 Td (mixing )Tj 0.239 g 0.05 Tc 10.5727 0 0 10.4 310.94 108.25 Tm (of )Tj 0.0106 Tc 10.4 0 0 10.4 321.99 108.25 Tm (inspired )Tj -0.0125 Tc 3.554 0 Td (gas )Tj -0.0059 Tc 1.577 0 Td (with )Tj 0.176 g 0.0099 Tc 2.031 0 Td (residual )Tj 0.239 g -0.0125 Tc 3.5 0 Td (gas )Tj -0.0224 Tc 1.569 0 Td (in )Tj 0.0373 Tc 1.021 0 Td (the )Tj -0.0219 Tc 1.561 0 Td (face )Tj ET BT /Suspect <>BDC 0.176 g /C0_0 1 Tf 0 Tc 4.896 0 0 7.68 495.85 108.25 Tm <006D0061007E006B002C0020>Tj EMC ET BT 0.239 g /T1_0 1 Tf 0.0456 Tc 10.4 0 0 10.4 523.57 108.25 Tm (and )Tj 0.0373 Tc -20.492 -1.016 Td (an )Tj 0.176 g 0.0237 Tc 1.294 0 Td (inadequate )Tj 0.239 g -0.0166 Tc 4.794 0 Td (seal )Tj 0.05 Tc 10.5727 0 0 10.4 392.54 97.68 Tm (of )Tj 0.0143 Tc 10.4 0 0 10.4 404.13 97.68 Tm (the )Tj 0.0062 Tc 1.524 0 Td (mask )Tj 0.0074 Tc 2.437 0 Td (for )Tj 0.0131 Tc 1.474 0 Td (some )Tj 0.0167 Tc 2.358 0 Td (expenments. )Tj 0.0277 Tc -15.779 -1.062 Td (During )Tj 0.0137 Tc 3.179 0 Td (expiration )Tj 0.0143 Tc 4.438 0 Td (the )Tj ET BT /Suspect <>BDC 0.176 g /T1_0 1 Tf -0.035 Tc 9.7748 0 0 10.4 416.12 86.64 Tm (PH)Tj /T1_2 1 Tf 0 Tc 6.2 0 0 6.2 428.59 84.25 Tm (2)Tj /T1_0 1 Tf 10.4 0 0 10.4 432.38 86.64 Tm (o )Tj EMC ET BT 0.239 g /T1_0 1 Tf 0.05 Tc 10.7518 0 0 10.4 440.53 86.64 Tm (at )Tj 0.0143 Tc 10.4 0 0 10.4 451.65 86.64 Tm (the )Tj 0.017 Tc 1.528 0 Td (pharynx )Tj -0.035 Tc 10.3253 0 0 10.4 505.32 86.64 Tm (\(fig. )Tj 10.3241 0 0 10.4 524.98 86.64 Tm (5B\) )Tj 10.1489 0 0 10.4 310.96 75.6 Tm (is )Tj 0.176 g -0.0327 Tc 10.4 0 0 10.4 320.55 75.6 Tm (less )Tj 0.239 g 0.0274 Tc 1.76 0 Td (than )Tj 0.0143 Tc 2.169 0 Td (the )Tj 0.0215 Tc 1.604 0 Td (saturation )Tj 0.0029 Tc 4.536 0 Td (value )Tj 0.05 Tc 11.3843 0 0 10.4 450.6 75.6 Tm (at )Tj 0.0135 Tc 10.4 0 0 10.4 462.73 75.6 Tm (body )Tj 0.0218 Tc 2.396 0 Td (temperature )Tj ET endstream endobj 27 0 obj <>stream Hd͊zy8 >sRhF^#y QG#Oç==o/ϧ;c_mӷKv|~_oo~y>}~W=|z>{O݇q~?>Ï?o+~ߒ~;%zΏx߽w;>lp?(O?{wٸ^ PZUuTGu^5P5FjFDMԤU PjVjUmFmک]uPuNNE]E5|| _#_k55|| _#_k55|| _#_k55|| _#_k5Z||-_+_kZ||-_+_kZ||-_+_kZ||-_+_ku:||_'_uu:||_'_uu:||_'_uu:||_'_uz||=_/_z||=_/_z||=_/_z||=_/_ || ߀o77 || ߀o77 || ߀o77 || ߀o77 KG#(~? ?G#(~? ?G#(~? ?G#(~? 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EMC /Suspect <>BDC 0.498 g 9.1 0 0 9.1 193.81 683.29 Tm (')Tj 0.176 g 0.512 0 Td (I )Tj EMC /Suspect <>BDC /T1_0 1 Tf 14.2 0 0 14.2 98.65 678.97 Tm (\225 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 7.5001 0 0 7.5001 175.96 679.92 Tm (I )Tj EMC /Suspect <>BDC 0.655 g /T1_0 1 Tf 3.9001 0 0 3.9001 215.97 684.24 Tm (o )Tj EMC /Suspect <>BDC 0.725 0.725 0.722 rg /T1_1 1 Tf 1.459 0 Td (I )Tj EMC /Suspect <>BDC 0.345 g 6.3001 0 0 6.3001 238.96 682.8 Tm (')Tj 0.176 g 0.9 0 Td (I )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 8.8 0 0 8.8 46.47 674.65 Tm (0 )Tj EMC /Suspect <>BDC 0.498 g /T1_1 1 Tf 4.5001 0 0 4.5001 100.2 678 Tm (I )Tj EMC ET BT 0.655 g /T1_1 1 Tf 10.1 0 0 10.1 123.71 674.17 Tm (' )Tj ET BT /Suspect <>BDC 0.114 g /T1_1 1 Tf 13.1 0 0 13.1 197.08 677.05 Tm (\225 )Tj EMC /Suspect <>BDC 1.759 -0.037 Td (\225 )Tj EMC /Suspect <>BDC 0.176 g 14 0 0 14 243.14 676.56 Tm (\225 )Tj EMC /Suspect <>BDC 0.345 g 0.05 Tc 13.5021 0 0 11.1 198.35 669.36 Tm (I' )Tj EMC /Suspect <>BDC 0.655 g 0 Tc 3.6 0 0 3.6 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Tm (I )Tj EMC /Suspect <>BDC 0.176 g 7.5001 0 0 7.5001 186.04 605.53 Tm (I )Tj EMC /Suspect <>BDC 0.345 g /T1_0 1 Tf 0.05 Tc 7.4484 0 0 7.3001 62.36 590.65 Tm (20 )Tj EMC /Suspect <>BDC 0.263 g /T1_1 1 Tf 0 Tc 6.3001 0 0 6.3001 72.86 573.85 Tm (\225)Tj 0.435 g 0.05 Tc 6.6995 0 0 6.3001 77.18 573.85 Tm (\225G)Tj 0.263 g -0.035 Tc 6.2865 0 0 6.3001 84.97 573.85 Tm (AS )Tj EMC ET BT 0.345 g /T1_1 1 Tf 0.027 Tc 6.3001 0 0 6.3001 97.33 573.85 Tm (\(EXP\) )Tj ET BT /Suspect <>BDC 0.114 g /T1_1 1 Tf 0 Tc 6.3001 0 0 6.3001 122.7824 573.85 Tm (\225)Tj 0.345 g 0.0209 Tc 0.914 0 Td (\225WALL )Tj EMC /Suspect <>BDC 0.263 g -0.0145 Tc 3.503 0 Td (\(INSP\) )Tj EMC /Suspect <>BDC 0.05 Tc 7.4759 0 0 6.3001 177.02 573.85 Tm ("'GAS )Tj EMC /Suspect <>BDC 0.345 g 0.0312 Tc 6.3001 0 0 6.3001 201.01 573.85 Tm (\(INSP\) )Tj EMC /Suspect <>BDC 0.176 g 0 Tc 4.116 0 Td (\225)Tj 0.345 g -0.035 Tc 6.1979 0 0 6.3001 231.75 573.85 Tm (\225GAS )Tj EMC /Suspect <>BDC -0.0088 Tc 6.3001 0 0 6.3001 248.05 573.85 Tm 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/T1_0 1 Tf 0.05 Tc 22.1966 0 0 15.4 77.02 460.56 Tm (--)Tj 0 Tc 15.4 0 0 15.4 102.54 460.56 Tm (-)Tj 0.05 Tc 22.1966 0 0 15.4 126.46 460.56 Tm [(--)-315(--)]TJ 22.8902 0 0 12 174.45 461.53 Tm (--)Tj 0.572 g 23.5839 0 0 15.4 221 460.56 Tm (--)Tj 0.498 g 1.079 0 Td (--)Tj ET BT /Suspect <>BDC 0.263 g /T1_1 1 Tf 4.7342 0 0 3.7001 51.76 462 Tm (\(/\) )Tj EMC ET BT /T1_0 1 Tf 0 Tc 6.9001 0 0 6.9001 65.2 459.61 Tm (6 )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 22.4 0 0 22.4 196.85 451.93 Tm (r )Tj EMC /Suspect <>BDC 6.3001 0 0 6.3001 51.84 457.21 Tm (w )Tj EMC /Suspect <>BDC 15.7 0 0 15.7 172.54 451.93 Tm (+ )Tj EMC /Suspect <>BDC /C0_0 1 Tf 4.32 0 0 9.12 221.29 450 Tm <007E0020>Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf 3.9001 0 0 3.9001 246.62 457.69 Tm (I )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 0.05 Tc 5.9598 0 0 5.1 51.78 452.89 Tm (0: )Tj EMC /Suspect <>BDC 0.114 g /T1_1 1 Tf 0 Tc 14 0 0 14 245.06 450 Tm (\225 )Tj EMC /Suspect <>BDC 0.263 g 0.05 Tc 5.8029 0 0 3.7001 51.26 449.53 Tm (\(L )Tj EMC /Suspect <>BDC 0.176 g 0 Tc 15.2 0 0 15.2 76.55 441.84 Tm (+ )Tj EMC /Suspect <>BDC 0.263 g 15.4 0 0 15.4 100.55 440.41 Tm (+ )Tj EMC /Suspect <>BDC /T1_0 1 Tf 28.4 0 0 28.4 125.3 437.53 Tm (\225 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 15.5 0 0 15.5 149.03 442.33 Tm (+ )Tj EMC /Suspect <>BDC 0.572 g 4.6 0 0 4.6 246.6 449.53 Tm (I )Tj EMC ET BT 0.435 g /T1_1 1 Tf 11 0 0 11 205.3 440.41 Tm (' )Tj ET BT /Suspect <>BDC 0.263 g /T1_0 1 Tf 15.3 0 0 15.3 51.68 437.53 Tm (a )Tj EMC ET BT /T1_0 1 Tf 6.9001 0 0 6.9001 65.73 436.09 Tm (4 )Tj ET BT /Suspect <>BDC /T1_5 1 Tf 10.8 0 0 10.8 179.48 433.69 Tm (t )Tj EMC /Suspect <>BDC 0.176 g /T1_4 1 Tf 8.4 0 0 8.4 203.43 438.97 Tm (T )Tj EMC /Suspect <>BDC 0.263 g /C0_0 1 Tf 4.8 0 0 5.28 51.85 431.76 Tm <007E0020>Tj EMC /Suspect <>BDC /T1_0 1 Tf -0.0056 Tc 4.7 0 0 4.7 51.79 427.44 Tm (0:: )Tj EMC /Suspect <>BDC 0.435 g /T1_1 1 Tf 0 Tc 4.5001 0 0 4.5001 229.32 426 Tm (I )Tj EMC /Suspect <>BDC 5.227 0 Td (I )Tj EMC /Suspect <>BDC 0.263 g 0.05 Tc 5.148 0 0 3.7001 51.76 424.09 Tm (<\( )Tj EMC /Suspect <>BDC 0.176 g /T1_4 1 Tf 0 Tc 8.4 0 0 8.4 227.43 419.28 Tm (T )Tj EMC /Suspect <>BDC 0.263 g 2.857 0 Td (T )Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf 0.0075 Tc 6.6 0 0 6.6 51.71 419.28 Tm (n. )Tj EMC /Suspect <>BDC 0.263 g -0.035 Tc 7.3991 0 0 9.6 51.34 408.25 Tm (ffi )Tj EMC /Suspect <>BDC /T1_0 1 Tf 0 Tc 6.9001 0 0 6.9001 65.72 412.09 Tm (2 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0.0364 Tc 10 0 0 10 51.31 400.09 Tm (ti )Tj EMC ET BT 0.435 g /T1_1 1 Tf 0 Tc 9.2 0 0 9.2 84.84 401.53 Tm (' )Tj ET BT /Suspect <>BDC 0.498 g /T1_1 1 Tf 6.3001 0 0 6.3001 109.27 402.97 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 29.3 0 0 29.3 131.14 389.05 Tm (')Tj 0.345 g 0.281 0 Td (\267 )Tj EMC /Suspect <>BDC 4.5001 0 0 4.5001 157.8 400.56 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 6.6 0 0 6.6 165.9 400.56 Tm (I )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 0.05 Tc 22.8739 0 0 14.4 83.73 394.81 Tm ('; )Tj EMC /Suspect <>BDC 0.176 g /T1_4 1 Tf 0 Tc 19.8 0 0 19.8 107.82 393.37 Tm (u )Tj EMC /Suspect <>BDC 0.263 g /T1_1 1 Tf 11.6 0 0 11.6 186.44 395.28 Tm (; )Tj EMC /Suspect <>BDC /C0_0 1 Tf 3.84 0 0 10.08 211.21 391.44 Tm <007E0020>Tj EMC /Suspect <>BDC /T1_1 1 Tf 14.5 0 0 14.5 235.44 391.93 Tm (+ )Tj EMC ET BT 0.435 g /T1_1 1 Tf 15.6 0 0 15.6 259.48 390.49 Tm (' )Tj ET BT /Suspect <>BDC 0.176 g /T1_0 1 Tf -0.0016 Tc 6.5001 0 0 6.5001 51.77 394.81 Tm (3: )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0 Tc 22 0 0 22 138.91 383.28 Tm (' )Tj EMC /Suspect <>BDC /T1_4 1 Tf 0.05 Tc 12.3533 0 0 9.9 156.35 391.93 Tm (T' )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0 Tc 18.7001 0 0 18.7001 257.95 388.09 Tm (\225 )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 6.8001 0 0 6.8001 66.17 387.61 Tm (0 )Tj EMC /Suspect <>BDC 0.114 g /T1_1 1 Tf 6.3001 0 0 6.3001 72.38 369.84 Tm (\225)Tj 0.435 g 0.838 0 Td (\225)Tj 0.263 g -0.035 Tc 6.2268 0 0 6.3001 81.51 369.84 Tm (GAS )Tj EMC /Suspect <>BDC 0.05 Tc 6.6035 0 0 6.3001 97.81 369.84 Tm (\(EXP\) )Tj EMC /Suspect <>BDC 0.176 g 0 Tc 6.3001 0 0 6.3001 125.66 369.84 Tm (\225)Tj 0.345 g -0.0226 Tc 0.686 0 Td (=GAS )Tj EMC /Suspect <>BDC 0.263 g 0.0464 Tc 3.046 0 Td (\(INSP\) )Tj EMC /Suspect <>BDC 0.114 g 0 Tc 4.802 0 Td (\225)Tj 0.263 g 0.838 0 Td (\225 )Tj EMC ET BT 0.345 g /T1_1 1 Tf -0.035 Tc 5.9873 0 0 6.3001 189.51 369.84 Tm (GAS )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 6.3449 0 0 6.3001 206.29 369.84 Tm (\(INPUT\) )Tj EMC /Suspect <>BDC 6.5653 0 0 6.3001 40.24 338.65 Tm (SITE )Tj EMC /Suspect <>BDC 0.263 g -0.0263 Tc 6.3001 0 0 6.3001 95.05 338.16 Tm (AIRWAY )Tj EMC /Suspect <>BDC 0.345 g -0.035 Tc 6.1523 0 0 6.3001 122.32 338.16 Tm (OPENING )Tj EMC /Suspect <>BDC 0.001 Tc 6.3001 0 0 6.3001 203.38 337.69 Tm (PHARYNX )Tj EMC /Suspect <>BDC 0.435 g 0.05 Tc 7.8689 0 0 6.3001 39.66 328.56 Tm (PAn)Tj 0.263 g 0 Tc 6.3001 0 0 6.3001 55.08 328.56 Tm (l )Tj EMC /Suspect <>BDC 0.345 g 0.0309 Tc 4.797 0 Td (NA)Tj 0.498 g 0.05 Tc 6.3719 0 0 6.3001 94 328.56 Tm (SAL )Tj EMC /Suspect <>BDC 0.263 g 0.0166 Tc 6.3001 0 0 6.3001 137.19 328.09 Tm (ORAL )Tj EMC /Suspect <>BDC 0.345 g 0.0119 Tc 7.535 0 Td (NASAL )Tj EMC /Suspect <>BDC -0.035 Tc 6.1203 0 0 6.3001 235.12 328.09 Tm (ORAL )Tj EMC /Suspect <>BDC 0.435 g 6.0529 0 0 6.3001 39.27 318.97 Tm (GROUP )Tj EMC /Suspect <>BDC 0.263 g 0 Tc 6.3001 0 0 6.3001 74.74 318.97 Tm (N)Tj 0.435 g -0.035 Tc 6.0161 0 0 6.3001 78.64 318.97 Tm (OR)Tj 0.263 g 0 Tc 6.3001 0 0 6.3001 87.7 318.97 Tm (M )Tj EMC /Suspect <>BDC 0.345 g -0.035 Tc 6.0475 0 0 6.3001 105.51 318.97 Tm (CF )Tj EMC /Suspect <>BDC 6.2863 0 0 6.3001 125.14 318.49 Tm (NORM )Tj EMC /Suspect <>BDC 0.263 g -0.0097 Tc 6.3001 0 0 6.3001 153.99 318.49 Tm (CF )Tj EMC /Suspect <>BDC -0.035 Tc 5.9555 0 0 6.3001 174.11 318.49 Tm (NORM )Tj EMC /Suspect <>BDC -0.0097 Tc 6.3001 0 0 6.3001 202.95 318 Tm (CF )Tj EMC /Suspect <>BDC 0.345 g -0.035 Tc 5.9555 0 0 6.3001 222.59 318 Tm (NORM )Tj EMC /Suspect <>BDC 0.263 g 0.05 Tc 6.3767 0 0 6.3001 250.95 318 Tm (CF )Tj EMC /Suspect <>BDC 0.498 g 0 Tc 4.5001 0 0 4.5001 126.6 312.25 Tm (I )Tj EMC /Suspect <>BDC 0.263 g -0.035 Tc 6.1047 0 0 11.6 173.6 308.89 Tm (... )Tj EMC /Suspect <>BDC /T1_0 1 Tf 9.9585 0 0 20.6 180.32 308.89 Tm (,. )Tj EMC /Suspect <>BDC 0.176 g 18.0736 0 0 32 197.38 310.33 Tm (... )Tj EMC /Suspect <>BDC 0.263 g /T1_1 1 Tf 9.2774 0 0 19.2001 221.99 309.37 Tm (.. )Tj EMC /Suspect <>BDC 0.176 g 0 Tc 23.8 0 0 23.8 245.93 296.41 Tm (' )Tj EMC /Suspect <>BDC /T1_0 1 Tf 15.1 0 0 15.1 125.04 304.09 Tm (\225 )Tj EMC ET BT 0.435 g /T1_1 1 Tf 18.4 0 0 18.4 76.78 304.09 Tm (. )Tj ET BT /Suspect <>BDC 0.572 g /T1_1 1 Tf 3.6 0 0 3.6 102.14 304.09 Tm (I )Tj EMC /Suspect <>BDC 5.9001 0 0 5.9001 126.56 302.65 Tm (I )Tj EMC /Suspect <>BDC 4.9001 0 0 4.9001 151.07 305.05 Tm (I )Tj EMC ET BT 0.498 g /T1_0 1 Tf 5.2 0 0 5.2 199.15 306 Tm (o )Tj ET BT /Suspect <>BDC 0.572 g /T1_1 1 Tf 4.9001 0 0 4.9001 206.27 306 Tm (I )Tj EMC /Suspect <>BDC 0.345 g 20.5 0 0 20.5 253.83 291.12 Tm (I )Tj EMC /Suspect <>BDC 0.176 g /T1_0 1 Tf 14.2 0 0 14.2 75.61 296.41 Tm (\225 )Tj EMC /Suspect <>BDC 14.1 0 0 14.1 100.57 296.41 Tm (\225 )Tj EMC /Suspect <>BDC 15.1 0 0 15.1 149.52 297.37 Tm (\225 )Tj EMC /Suspect <>BDC 0.263 g /T1_1 1 Tf 7.2 0 0 7.2 77.08 293.53 Tm (I )Tj EMC /Suspect <>BDC 0.498 g 4.5001 0 0 4.5001 102.12 296.41 Tm (I )Tj EMC /Suspect <>BDC 10.88 -0.107 Td (I )Tj EMC /Suspect <>BDC 0.345 g 9.1 0 0 9.1 230.15 290.16 Tm (I )Tj EMC ET BT 0.263 g /T1_0 1 Tf -0.035 Tc 9.1867 0 0 10.3 60.38 290.16 Tm (eo )Tj ET BT /Suspect <>BDC /C0_0 1 Tf 0 Tc 5.76 0 0 10.56 44.17 278.16 Tm <007E0020>Tj EMC /Suspect <>BDC 0.176 g /T1_1 1 Tf 13.8 0 0 13.8 228.77 279.12 Tm (" )Tj EMC /Suspect <>BDC /T1_0 1 Tf 12.2 0 0 12.2 252.73 282 Tm (" )Tj EMC ET BT 0.435 g /T1_1 1 Tf 3.6 0 0 3.6 229.86 282 Tm (l )Tj ET BT /Suspect <>BDC 0.263 g /T1_1 1 Tf 7.2 0 0 7.2 254.2 280.56 Tm (I )Tj EMC /Suspect <>BDC /C0_0 1 Tf 4.8 0 0 3.84 44.65 272.41 Tm <007E0020>Tj EMC /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 7.9089 0 0 4.8001 44.14 268.09 Tm (f-)Tj EMC /Suspect <>BDC /T1_0 1 Tf 8.426 0 0 7.6 59.9 265.69 Tm (60 )Tj EMC /Suspect <>BDC 0 Tc 8.1 0 0 8.1 44.56 261.37 Tm (0 )Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf 18.2001 0 0 18.2001 156.46 249.85 Tm (I )Tj EMC /Suspect <>BDC 0.263 g /T1_5 1 Tf 8.8 0 0 8.8 44.46 254.16 Tm (i )Tj EMC /Suspect <>BDC /T1_1 1 Tf 8.4 0 0 8.4 83.77 248.89 Tm (I )Tj EMC /Suspect <>BDC 0.345 g 12.1 0 0 12.1 132.15 247.93 Tm (I )Tj EMC ET BT 0.435 g /T1_1 1 Tf 32.5 0 0 32.5 212.13 223.93 Tm (j )Tj ET BT /Suspect <>BDC 0.263 g /T1_1 1 Tf -0.035 Tc 4.374 0 0 7.2 44.57 248.89 Tm (=> )Tj EMC /Suspect <>BDC 0 Tc 8.4 0 0 8.4 107.77 247.44 Tm (I )Tj EMC /Suspect <>BDC /T1_0 1 Tf -0.0017 Tc 5.4001 0 0 5.4001 44.51 245.05 Tm (:J: )Tj EMC /Suspect <>BDC 0.05 Tc 8.8142 0 0 7.6 59.96 241.21 Tm (40 )Tj EMC ET BT 0.176 g /T1_5 1 Tf 0 Tc 13 0 0 13 82.48 238.8 Tm (T )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 14 0 0 14 106.37 236.89 Tm (" )Tj EMC /Suspect <>BDC 16.5 0 0 16.5 131.3 234.97 Tm (" )Tj EMC /Suspect <>BDC 14.6 0 0 14.6 155.32 238.33 Tm (" )Tj EMC /Suspect <>BDC 0.263 g /T1_6 1 Tf 7.7 0 0 7.7 44.13 236.41 Tm (w )Tj EMC /Suspect <>BDC 0.176 g /T1_1 1 Tf 11.1 0 0 11.1 107.69 234.01 Tm (I )Tj EMC ET BT 0.345 g /T1_1 1 Tf 6.8001 0 0 6.8001 132.26 237.37 Tm (1 )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 24.1 0 0 24.1 156.29 217.21 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 0.282 0 Td (, )Tj EMC /Suspect <>BDC 0.263 g -0.035 Tc 5.2879 0 0 7.5001 44.54 230.16 Tm (i:!: )Tj EMC /Suspect <>BDC 0.176 g 0 Tc 9.1 0 0 9.1 90.47 230.16 Tm (I )Tj EMC /Suspect <>BDC 0.435 g 5.433 0.107 Td (I )Tj EMC /Suspect <>BDC 0.114 g 13 0 0 13 187.83 226.8 Tm (! )Tj EMC /Suspect <>BDC 0.176 g 8.5 0 0 8.5 236.41 230.65 Tm (I )Tj EMC /Suspect <>BDC 0.263 g 0.0364 Tc 10 0 0 10 44.11 222.97 Tm (ti )Tj EMC /Suspect <>BDC 0 Tc 15 0 0 15 89.05 222.01 Tm (\225 )Tj EMC /Suspect <>BDC 0.176 g /T1_0 1 Tf 14.1 0 0 14.1 138.49 223.44 Tm (\225 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 13.1 0 0 13.1 235.48 223.93 Tm (\225 )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 0.0474 Tc 5.1 0 0 5.1 44.54 218.65 Tm (..J )Tj EMC /Suspect <>BDC 0.05 Tc 7.9139 0 0 7.6 60.91 216.73 Tm (20 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0 Tc 11.1 0 0 11.1 90.41 216.73 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 27.5 0 0 27.5 113.88 199.93 Tm (' )Tj EMC /Suspect <>BDC 0.263 g 13 0 0 13 139.32 215.76 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 3.803 0.075 Td (I )Tj EMC /Suspect <>BDC 3.655 -0.037 Td (I )Tj EMC ET BT /T1_1 1 Tf 24.7001 0 0 24.7001 259.36 203.76 Tm (' )Tj ET BT /Suspect <>BDC 0.263 g /T1_6 1 Tf 7.7 0 0 7.7 44.13 214.8 Tm (w )Tj EMC /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 6.5558 0 0 5.1 44.09 210.49 Tm (0: )Tj EMC /Suspect <>BDC 0 Tc 6.4001 0 0 6.4001 64.74 193.69 Tm (0 )Tj EMC /Suspect <>BDC 0.176 g /T1_1 1 Tf 6.3001 0 0 6.3001 70.94 174.49 Tm (\225 )Tj EMC /Suspect <>BDC 0.263 g 0.0028 Tc 0.914 0 Td (=GAS )Tj EMC ET BT /T1_1 1 Tf 0.05 Tc 6.6364 0 0 6.3001 97.8 174.49 Tm (\(EX )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 6.5204 0 0 6.3001 110.25 174.49 Tm (PI )Tj EMC /Suspect <>BDC 0.176 g 0 Tc 6.3001 0 0 6.3001 124.24 174.49 Tm (")Tj 0.435 g 0.05 Tc 7.7667 0 0 6.3001 129.87 174.49 Tm (:G)Tj 0.263 g -0.035 Tc 5.9167 0 0 6.3001 138.25 174.49 Tm (AS )Tj EMC /Suspect <>BDC 0.05 Tc 6.5695 0 0 6.3001 149.65 174.49 Tm (\(INS )Tj EMC /Suspect <>BDC 0.345 g 6.5204 0 0 6.3001 164.01 174.49 Tm (PI )Tj EMC /Suspect <>BDC 0.114 g 0 Tc 6.3001 0 0 6.3001 180.38 174.49 Tm (\225 )Tj EMC /Suspect <>BDC 0.345 g 0.762 0 Td (\225 )Tj EMC ET BT /T1_1 1 Tf -0.035 Tc 6.2268 0 0 6.3001 189.99 174.49 Tm (GAS )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 6.833 0 0 6.3001 205.8 174.49 Tm (\(INPUT\) )Tj EMC ET BT /T1_0 1 Tf -0.0077 Tc 8.4 0 0 8.4 38.36 153.85 Tm (Fig. )Tj 0.263 g -0.035 Tc 8.2321 0 0 8.4 53.73 153.85 Tm (4. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0196 Tc 8.4 0 0 8.4 68.63 153.85 Tm (Upper )Tj EMC ET BT /T1_0 1 Tf 0.0072 Tc 8.4 0 0 8.4 93.0404 153.85 Tm (airway )Tj -0.0037 Tc 3.151 0 Td (humidification )Tj -0.018 Tc 6.279 0 Td (in )Tj 0.0175 Tc 1.15 0 Td (normal )Tj 0.0269 Tc 3.306 0 Td (and )Tj 0.05 Tc 8.8292 0 0 8.4 225.51 153.85 Tm (CF )Tj 0.001 Tc 8.4 0 0 8.4 239.4 153.85 Tm (subjects )Tj 0.0081 Tc -23.927 -1.029 Td (breathing )Tj 0.0085 Tc 4.389 0 Td (ambient )Tj 0.345 g 0.0219 Tc 3.829 0 Td (air )Tj -0.0318 Tc 1.664 0 Td (th)Tj 0.176 g 0.0311 Tc 0.744 0 Td (rough )Tj 0.263 g 0.0197 Tc 3.027 0 Td (the )Tj 0 Tc 1.83 0 Td (nose )Tj 0.345 g 0.0269 Tc 2.335 0 Td (and )Tj 0.263 g 0.0229 Tc 2.064 0 Td (mouth. )Tj -0.006 Tc 3.476 0 Td (\(Symbols )Tj -0.0004 Tc -23.361 -1.086 Td (represent )Tj 0.0043 Tc 3.999 0 Td (mean )Tj 0.176 g -0.0179 Tc 2.514 0 Td (values )Tj 0.263 g 0.0269 Tc 2.793 0 Td (and )Tj -0.0023 Tc 1.893 0 Td (vertical )Tj 0.0196 Tc 3.318 0 Td (bars )Tj 0.345 g 0.0263 Tc 1.985 0 Td (span )Tj 0.263 g 0.0197 Tc 2.24 0 Td (the )Tj 0.0025 Tc 1.601 0 Td (range )Tj 0.345 g 0.05 Tc 8.9033 0 0 8.4 230.8 136.09 Tm (of )Tj ET BT /Suspect <>BDC 0.263 g /T1_0 1 Tf -0.035 Tc 6.8637 0 0 8.4 240.41 136.09 Tm (aU )Tj EMC ET BT /T1_0 1 Tf 0.0391 Tc 8.4 0 0 8.4 250.96 136.09 Tm (data )Tj -0.0104 Tc -25.304 -1.087 Td (points\): )Tj -0.035 Tc 8.2476 0 0 8.4 70.55 126.96 Tm (A. )Tj 0.0112 Tc 8.4 0 0 8.4 85.37 126.96 Tm (Temperature: )Tj 0.345 g -0.0098 Tc 6.286 0 Td (local )Tj 0.263 g -0.0015 Tc 2.743 0 Td (gas )Tj 0.345 g 0.049 Tc 2.113 0 Td (on )Tj 0.263 g 0.0143 Tc 1.83 0 Td (inspiration )Tj 0.0269 Tc 5.199 0 Td (and )Tj 0.049 Tc 2.286 0 Td (on )Tj 0.0063 Tc -26.115 -1.029 Td (expiration, )Tj 0.0045 Tc 4.745 0 Td (local )Tj 0.0072 Tc 2.285 0 Td (airway )Tj 0.0093 Tc 3.081 0 Td (surface )Tj 0.345 g -0.0046 Tc 3.202 0 Td (\(wall\) )Tj 0.05 Tc 8.4599 0 0 8.4 172.23 118.32 Tm (and )Tj 0.263 g 0.0079 Tc 8.4 0 0 8.4 188.09 118.32 Tm (inhaled )Tj -0.0015 Tc 3.371 0 Td (gas )Tj 0.345 g -0.001 Tc 1.654 0 Td (\(input\); )Tj 0.176 g -0.035 Tc 7.8194 0 0 8.4 259.17 118.32 Tm (B. )Tj 0.263 g 0.0205 Tc 8.4 0 0 8.4 37.89 109.2 Tm (Water )Tj 0.0288 Tc 2.973 0 Td (vapour )Tj 0.0146 Tc 3.375 0 Td (partial )Tj -0.0069 Tc 3.143 0 Td (pressure: )Tj -0.024 Tc 4.105 0 Td (local )Tj -0.0015 Tc 2.343 0 Td (gas )Tj -0.0082 Tc 1.827 0 Td (on )Tj 0.0143 Tc 1.487 0 Td (inspiration )Tj 0.0269 Tc 4.913 0 Td (and )Tj 0.345 g -0.0082 Tc 2 0 Td (on )Tj 0.263 g 0.012 Tc -26.23 -1.027 Td (expiration, )Tj 0.05 Tc 8.4599 0 0 8.4 79.11 100.57 Tm (and )Tj -0.0016 Tc 8.4 0 0 8.4 96.89 100.57 Tm (inhaled )Tj -0.0015 Tc 3.486 0 Td (gas )Tj 0.0029 Tc 1.882 0 Td (\(input\). )Tj 0.0042 Tc 3.663 0 Td (Equilibrium )Tj 0.176 g 0 Tc 5.433 0 Td (w)Tj 0.345 g 0.0384 Tc 0.677 0 Td (ater )Tj 0.263 g 0.0288 Tc 2.121 0 Td (vapour )Tj -0.001 Tc -24.282 -1.087 Td (pressure )Tj 0.0339 Tc 3.875 0 Td (at )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 8.275 0 0 8.4 81.98 91.44 Tm (37)Tj 0.435 g -0.0067 Tc 8.4 0 0 8.4 89.6 91.44 Tm ("C )Tj EMC ET BT 0.263 g /T1_0 1 Tf 0.0017 Tc 8.4 0 0 8.4 103.1324 91.44 Tm (indicated )Tj -0.019 Tc 4.238 0 Td (by )Tj 0.0197 Tc 1.539 0 Td (the )Tj 0.0139 Tc 1.83 0 Td (horizontal )Tj 0.345 g -0.0254 Tc 4.736 0 Td (line; )Tj 0.263 g 0 Tc 2.226 0 Td (C)Tj 0.435 g 0.733 0 Td (. )Tj 0.263 g 0.0068 Tc 0.758 0 Td (Relative )Tj 0.0076 Tc -23.825 -1.086 Td (humidity )Tj 0.345 g 0.05 Tc 8.4649 0 0 8.4 72.38 82.32 Tm (\(at )Tj 0.263 g -0.0015 Tc 8.4 0 0 8.4 85.85 82.32 Tm (gas )Tj 0.0091 Tc 1.835 0 Td (temperature\))Tj 0.435 g 0 Tc 5.235 0 Td (: )Tj 0.263 g -0.0098 Tc 0.702 0 Td (local )Tj -0.0015 Tc 2.4 0 Td (gas )Tj 0.049 Tc 1.827 0 Td (on )Tj 0.0086 Tc 1.544 0 Td (inspiration )Tj 0.0269 Tc 4.856 0 Td (and )Tj 0.049 Tc 2 0 Td (on )Tj 0.012 Tc -26.173 -1.029 Td (expiration, )Tj 0.0269 Tc 4.744 0 Td (and )Tj -0.0016 Tc 1.887 0 Td (inhaled )Tj -0.0015 Tc 3.257 0 Td (gas )Tj 0.345 g 0.0029 Tc 1.654 0 Td (\(input\). )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 6.5653 0 0 6.3001 292.72 729.36 Tm (SITE )Tj EMC /Suspect <>BDC 0.0042 Tc 6.3001 0 0 6.3001 347.05 727.92 Tm (AIRWAY )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 4.08 0 0 6.72 374.4 727.92 Tm <004F0050007E007E0049004E>Tj 0.498 g 1.44 0 0 6.72 396.96 727.92 Tm <003A003A003A>Tj 0.345 g 3.84 0 0 6.72 398.89 727.92 Tm <0047>Tj 0.572 g 1.44 0 0 6.72 401.29 727.92 Tm <0027>Tj 0.725 0.725 0.722 rg 8.88 0 0 6.72 402.73 727.92 Tm <002D002D>Tj 0.572 g 7.2 0 0 6.72 420.49 727.92 Tm <002C002D002D002D>Tj 0.435 g 1.7455 0 0 6.72 449.29 727.92 Tm <002D0027002D0050002D0027002D0027004800220022>Tj 0.263 g 4.32 0 0 6.72 464.65 727.92 Tm <0041>Tj 0.435 g 1.2 0 0 6.72 468.49 727.92 Tm <003A002100660052>Tj 0.572 g <002E002E0021002E>Tj 0.345 g 1.824 0 0 6.72 473.77 727.92 Tm <00590021002E0021004E>Tj 0.572 g 1.6 0 0 6.72 482.89 727.92 Tm <002E003A0021>Tj 0.345 g 3.84 0 0 6.72 483.36 727.92 Tm <0058>Tj 0.655 g 9.6 0 0 6.72 487.68 727.92 Tm <002D002D002D>Tj 0.498 g 2.64 0 0 6.72 516.48 727.92 Tm <002D002E0020>Tj EMC /Suspect <>BDC 0.263 g /T1_1 1 Tf 0.0129 Tc 6.3001 0 0 6.3001 292.18 719.76 Tm (PATH )Tj EMC ET BT 0.345 g /T1_1 1 Tf 0.031 Tc 6.3001 0 0 6.3001 338.2589 719.76 Tm (NASAL )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.0088 Tc 6.3001 0 0 6.3001 389.6677 719.76 Tm (ORAL )Tj EMC ET BT 0.263 g /T1_1 1 Tf 0.0119 Tc 6.3001 0 0 6.3001 437.139 719.76 Tm (NASAL )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 6.2696 0 0 6.3001 488.07 719.76 Tm (ORA)Tj 0.435 g 0 Tc 6.3001 0 0 6.3001 500.99 719.76 Tm (L )Tj EMC /Suspect <>BDC 0.345 g -0.035 Tc 6.1905 0 0 6.3001 291.75 710.65 Tm (GROUP )Tj EMC ET BT 0.263 g /T1_0 1 Tf 0.05 Tc 7.8864 0 0 7.6 312.45 681.85 Tm (46 )Tj ET BT /Suspect <>BDC 0.435 g /T1_1 1 Tf 0 Tc 18 0 0 18 295.99 670.33 Tm (-)Tj EMC /Suspect <>BDC 0.345 g 6.1 0 0 6.1 296.53 669.36 Tm (u )Tj EMC /Suspect <>BDC 0.435 g /T1_0 1 Tf -0.035 Tc 6.3221 0 0 7.1 296.43 662.65 Tm (!... )Tj EMC /Suspect <>BDC 0 Tc 8 0 0 8 297.11 655.92 Tm (w )Tj EMC ET BT 0.263 g /T1_0 1 Tf 0.05 Tc 7.4225 0 0 7.3001 312.45 657.36 Tm (42 )Tj ET BT /Suspect <>BDC 0.345 g /T1_0 1 Tf 0.0465 Tc 4 0 0 4 296.6 652.09 Tm (Q:. )Tj EMC /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 4.8114 0 0 7.2 297.04 646.8 Tm (=> )Tj EMC /Suspect <>BDC 0.05 Tc 7.9089 0 0 4.8001 296.62 642.97 Tm (f-)Tj EMC /Suspect <>BDC 5.148 0 0 3.7001 297.04 639.12 Tm (<\( )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 7.5807 0 0 7.3001 313.35 633.36 Tm (38 )Tj EMC /Suspect <>BDC -0.0056 Tc 4.7 0 0 4.7 297.07 633.85 Tm (0:: )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0 Tc 6.2 0 0 6.2 297.12 630 Tm (w )Tj EMC /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 6.7445 0 0 7.3001 297.11 625.68 Tm (n. )Tj EMC /Suspect <>BDC /T1_1 1 Tf 4.8147 0 0 6.2 296.99 620.41 Tm (::E )Tj EMC /Suspect <>BDC 0.345 g /T1_0 1 Tf 0 Tc 8 0 0 8 297.11 616.56 Tm (w )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 7.1899 0 0 4.8001 297.1 611.76 Tm (f-)Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 7.5807 0 0 7.3001 312.87 608.41 Tm (34 )Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf 6.3601 0 0 6.3001 292.24 530.17 Tm (SITE )Tj EMC /Suspect <>BDC 0.263 g 0.0129 Tc 6.3001 0 0 6.3001 291.7 520.56 Tm (PATH )Tj EMC /Suspect <>BDC -0.035 Tc 6.1905 0 0 6.3001 291.27 511.44 Tm (GROUP )Tj EMC /Suspect <>BDC 0.345 g /C0_0 1 Tf 0 Tc 5.28 0 0 6.72 301.93 489.84 Tm <007E0020>Tj EMC /Suspect <>BDC 0.263 g 5.76 0 0 5.76 301.93 483.12 Tm <007E0020>Tj EMC ET BT /T1_0 1 Tf 6.4001 0 0 6.4001 316.21 482.65 Tm (8 )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 6.7 0 0 6.7 301.92 475.93 Tm (w )Tj EMC /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 7.1223 0 0 7.4001 302.33 472.09 Tm (a: )Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf 4.374 0 0 7.2 302.33 466.81 Tm (=> )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 0.05 Tc 4.6871 0 0 3.6 302.35 464.41 Tm (\(/\) )Tj EMC /Suspect <>BDC /T1_1 1 Tf 4.7342 0 0 3.7001 302.32 460.56 Tm (\(/\) )Tj EMC /Suspect <>BDC 0 Tc 6.7 0 0 6.7 302.4 455.76 Tm (w )Tj EMC /Suspect <>BDC 0.345 g /T1_0 1 Tf -0.035 Tc 7.1223 0 0 7.4001 302.33 451.93 Tm (a: )Tj EMC /Suspect <>BDC 6.7445 0 0 7.3001 302.39 448.09 Tm (n. )Tj EMC ET BT 0.263 g /T1_0 1 Tf 0 Tc 6.8001 0 0 6.8001 315.76 458.65 Tm (6 )Tj ET BT /Suspect <>BDC 0.435 g /T1_0 1 Tf 0.05 Tc 5.5791 0 0 5.1 302.29 440.89 Tm (..J )Tj EMC /Suspect <>BDC 0.263 g /T1_1 1 Tf 5.148 0 0 3.7001 302.32 438 Tm (<\( )Tj EMC ET BT /T1_0 1 Tf 0 Tc 6.9001 0 0 6.9001 316.29 435.61 Tm (4 )Tj ET BT /Suspect <>BDC 0.345 g /T1_1 1 Tf -0.035 Tc 6.5777 0 0 8.1 302.27 430.33 Tm (i= )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 7.1223 0 0 7.4001 302.33 426 Tm (a: )Tj EMC /Suspect <>BDC 0.05 Tc 4.6238 0 0 4.1 302.86 422.65 Tm (<\( )Tj EMC /Suspect <>BDC 0.345 g 4.7998 0 0 4 302.35 418.81 Tm (Q. )Tj EMC /Suspect <>BDC -0.035 Tc 6.4611 0 0 10.6 302.33 406.81 Tm (f5 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0 Tc 6.7 0 0 6.7 316.27 411.12 Tm (2 )Tj EMC /Suspect <>BDC 0.0364 Tc 10 0 0 10 302.35 399.12 Tm (ti )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf -0.0016 Tc 6.5001 0 0 6.5001 302.81 393.84 Tm (3: )Tj EMC /Suspect <>BDC 0 Tc 7.1 0 0 7.1 315.77 387.12 Tm (0 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 6.4757 0 0 6.3001 292.72 335.76 Tm (SI)Tj 0.435 g 0.0324 Tc 6.3001 0 0 6.3001 299.96 335.76 Tm (TE )Tj EMC /Suspect <>BDC 0.263 g -0.035 Tc 6.2746 0 0 6.3001 293.14 326.16 Tm (PAT)Tj 0.435 g 0 Tc 6.3001 0 0 6.3001 304.65 326.16 Tm (H )Tj EMC /Suspect <>BDC -0.035 Tc 6.0529 0 0 6.3001 291.75 316.56 Tm (GROUP )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 0.05 Tc 8.0403 0 0 7.6 312.34 288.25 Tm (80 )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 5.76 0 0 7.68 297.61 277.69 Tm <007E0020>Tj EMC /Suspect <>BDC 4.8 0 0 3.36 297.61 271.93 Tm <007E0020>Tj EMC /Suspect <>BDC /T1_1 1 Tf 0.05 Tc 7.9089 0 0 4.8001 297.58 267.12 Tm (f-)Tj EMC /Suspect <>BDC /T1_0 1 Tf 7.9579 0 0 7.6 312.86 263.76 Tm (60 )Tj EMC /Suspect <>BDC 0 Tc 7.8001 0 0 7.8001 297.52 261.37 Tm (0 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 6.8001 0 0 6.8001 297.7 255.61 Tm (j )Tj EMC /Suspect <>BDC -0.035 Tc 4.374 0 0 7.2 298.01 248.89 Tm (=> )Tj EMC /Suspect <>BDC /T1_0 1 Tf -0.0017 Tc 5.4001 0 0 5.4001 297.95 245.05 Tm (:J: )Tj EMC /Suspect <>BDC 0.05 Tc 8.3503 0 0 7.6 312.45 240.73 Tm (40 )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 5.28 0 0 7.2 297.61 234.01 Tm <007E0020>Tj EMC /Suspect <>BDC 5.28 0 0 9.6 297.61 223.93 Tm <007E0020>Tj EMC /Suspect <>BDC 0.176 g /T1_0 1 Tf 0.0474 Tc 5.1 0 0 5.1 297.98 219.61 Tm (..J )Tj EMC /Suspect <>BDC 0.263 g 0.05 Tc 8.3795 0 0 7.6 312.43 216.25 Tm (20 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 5.3111 0 0 4.8001 297.46 215.29 Tm (IU )Tj EMC /Suspect <>BDC /T1_0 1 Tf 5.9598 0 0 5.1 298.02 210.97 Tm (0: )Tj EMC /Suspect <>BDC 0 Tc 6.8001 0 0 6.8001 316.73 192.73 Tm (0 )Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf -0.035 Tc 6.1209 0 0 6.3001 326.75 710.65 Tm (NORM )Tj EMC /Suspect <>BDC 0.263 g -0.0097 Tc 6.3001 0 0 6.3001 357.51 710.65 Tm (CF )Tj EMC /Suspect <>BDC -0.035 Tc 6.2863 0 0 6.3001 378.1 710.65 Tm (NORM )Tj EMC /Suspect <>BDC 0.345 g 6.0475 0 0 6.3001 406.47 710.65 Tm (CF )Tj EMC /Suspect <>BDC 0.263 g 5.9555 0 0 6.3001 426.11 710.65 Tm (NORM )Tj EMC /Suspect <>BDC 0.345 g -0.0097 Tc 6.3001 0 0 6.3001 455.43 710.65 Tm (CF )Tj EMC /Suspect <>BDC 0.263 g -0.035 Tc 6.1209 0 0 6.3001 475.07 710.65 Tm (NORM )Tj EMC /Suspect <>BDC 0.345 g 6.0475 0 0 6.3001 504.39 710.65 Tm (CF )Tj EMC /Suspect <>BDC /C0_0 1 Tf 0 Tc 5.28 0 0 24.96 324 682.33 Tm <007E00740020>Tj EMC /Suspect <>BDC 0.435 g /T1_1 1 Tf 10.7 0 0 10.7 352.03 695.29 Tm (I )Tj EMC /Suspect <>BDC 0.345 g 8.1 0 0 8.1 377.54 696.73 Tm (I )Tj EMC /Suspect <>BDC 0.263 g 8.5 0 0 8.5 401.53 691.92 Tm (I )Tj EMC /Suspect <>BDC 0.176 g /T1_0 1 Tf 12.2 0 0 12.2 351.16 688.56 Tm (\225 )Tj EMC /Suspect <>BDC /T1_1 1 Tf 12 0 0 12 376.61 690 Tm (\225 )Tj EMC /Suspect <>BDC 0.345 g 0.0178 Tc 13 0 0 13 351.96 679.92 Tm (II )Tj EMC /Suspect <>BDC 0.263 g 0 Tc 9.7 0 0 9.7 377.49 684.24 Tm (I )Tj EMC /Suspect <>BDC 7.5001 0 0 7.5001 400.13 685.68 Tm (! )Tj EMC /Suspect <>BDC 0.176 g 14 0 0 14 356.45 667.44 Tm (" )Tj EMC /Suspect <>BDC 0.114 g 14.3 0 0 14.3 406.16 669.85 Tm (I )Tj EMC /Suspect <>BDC 0.435 g 9.8 0 0 9.8 357.81 666 Tm (I )Tj EMC /Suspect <>BDC 0.345 g 21.5 0 0 21.5 382.44 654 Tm (I )Tj EMC ET BT 0.263 g /T1_5 1 Tf 12.9 0 0 12.9 405.04 654.97 Tm (T )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 17.4564 0 0 32.4001 337.01 632.89 Tm (,, )Tj EMC /Suspect <>BDC /T1_0 1 Tf 0 Tc 14.2 0 0 14.2 342.97 620.89 Tm (\225 )Tj EMC /Suspect <>BDC 0.498 g /T1_1 1 Tf 7.5001 0 0 7.5001 343.96 617.05 Tm (I )Tj EMC /Suspect <>BDC 0.263 g /T1_4 1 Tf 20.5 0 0 20.5 381.2 634.8 Tm (1 )Tj EMC /Suspect <>BDC 0.176 g /T1_1 1 Tf 13.6 0 0 13.6 362.66 634.33 Tm (+ )Tj EMC /Suspect <>BDC 0.435 g 9.1 0 0 9.1 368.87 628.09 Tm (I )Tj EMC /Suspect <>BDC 0.263 g 13 0 0 13 387.96 625.21 Tm (I)Tj 0.498 g 0.407 0 Td (. )Tj EMC /Suspect <>BDC 0.176 g 13.1 0 0 13.1 367.48 620.89 Tm (\225 )Tj EMC /Suspect <>BDC 0.263 g 13 0 0 13 369.24 613.68 Tm (I )Tj EMC /Suspect <>BDC /T1_5 1 Tf 0.0335 Tc 15.1 0 0 15.1 387.09 613.21 Tm (jt )Tj EMC /Suspect <>BDC 0.435 g /T1_1 1 Tf 0 Tc 6.5001 0 0 6.5001 426.06 698.17 Tm (I )Tj EMC /Suspect <>BDC 0.176 g /T1_0 1 Tf 14.2 0 0 14.2 424.57 690.97 Tm (\225 )Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf 9.1 0 0 9.1 425.99 685.21 Tm (I )Tj EMC /Suspect <>BDC 0.655 g 4.8001 0 0 4.8001 412.67 644.41 Tm (I )Tj EMC /Suspect <>BDC 0.114 g 13 0 0 13 411.16 637.21 Tm (\225 )Tj EMC ET BT 0.572 g /T1_1 1 Tf 11.9 0 0 11.9 412.65 631.44 Tm (' )Tj ET BT /Suspect <>BDC 0.435 g /T1_1 1 Tf 6.5001 0 0 6.5001 417.9 630 Tm (I )Tj EMC /Suspect <>BDC 0.176 g /T1_0 1 Tf 15.1 0 0 15.1 416.4 622.8 Tm (\225 )Tj EMC /Suspect <>BDC 0.263 g 14.2 0 0 14.2 440.89 620.89 Tm (\225 )Tj EMC ET BT 0.345 g /T1_1 1 Tf 10.1 0 0 10.1 417.95 618 Tm (' )Tj ET BT /Suspect <>BDC 0.176 g /T1_0 1 Tf 19.3 0 0 19.3 435.05 615.61 Tm (\225)Tj 0.435 g 0.373 0 Td (\225 )Tj EMC /Suspect <>BDC 0.263 g 13.3 0 0 13.3 429.48 610.33 Tm (T)Tj 0.572 g 0.542 0 Td (l )Tj EMC /Suspect <>BDC 0.435 g /T1_1 1 Tf 6.6 0 0 6.6 451.02 693.36 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 13.1 0 0 13.1 449.56 686.17 Tm (\225 )Tj EMC /Suspect <>BDC 0.263 g 9.7 0 0 9.7 450.93 680.89 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 14 0 0 14 465.38 620.89 Tm (\225 )Tj EMC /Suspect <>BDC 0.435 g /T1_0 1 Tf 7.8001 0 0 7.8001 462.2 616.56 Tm (J)Tj 0.176 g 0.613 0 Td (l )Tj EMC /Suspect <>BDC 0.263 g /T1_5 1 Tf -0.035 Tc 12.1039 0 0 18 453.93 602.17 Tm (+r )Tj EMC /Suspect <>BDC 0.176 g /T1_1 1 Tf 0 Tc 9.1 0 0 9.1 475.43 695.76 Tm (I )Tj EMC /Suspect <>BDC /T1_0 1 Tf 12.3 0 0 12.3 474.04 690 Tm (\225 )Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf 9.1 0 0 9.1 475.43 684.73 Tm (I )Tj EMC /Suspect <>BDC 0.435 g 6.5001 0 0 6.5001 499.98 697.21 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 14 0 0 14 498.98 690 Tm (\225 )Tj EMC /Suspect <>BDC 0.345 g 10.7 0 0 10.7 499.87 684.24 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 14.3 0 0 14.3 479.6 626.17 Tm (I )Tj EMC ET BT 0.345 g /T1_1 1 Tf 14.3 0 0 14.3 491.1401 626.17 Tm [(. )-331(' )]TJ ET BT /Suspect <>BDC 0.435 g /T1_1 1 Tf 3.9001 0 0 3.9001 516.38 626.17 Tm (I )Tj EMC /Suspect <>BDC 0.263 g 27.6 0 0 27.6 478.03 610.8 Tm (r )Tj EMC /Suspect <>BDC -0.035 Tc 13.6228 0 0 21.2001 484.58 610.8 Tm (+' )Tj EMC /Suspect <>BDC /T1_5 1 Tf 17.2143 0 0 25.8 502.22 610.8 Tm (rp )Tj EMC /Suspect <>BDC 0.114 g /T1_1 1 Tf 0 Tc 6.3001 0 0 6.3001 325.34 567.12 Tm (\225 )Tj EMC /Suspect <>BDC 0.435 g -0.035 Tc 5.9471 0 0 6.3001 330.63 567.12 Tm (=G)Tj 0.263 g 6.2865 0 0 6.3001 338.41 567.12 Tm (AS )Tj EMC /Suspect <>BDC 0.0343 Tc 6.3001 0 0 6.3001 348.85 567.12 Tm (\(IN )Tj EMC /Suspect <>BDC 0.345 g 0.05 Tc 7.1532 0 0 6.3001 358.4 567.12 Tm (PUll )Tj EMC /Suspect <>BDC 0.263 g 6.4272 0 0 6.3001 379.1 567.12 Tm (\225=GAS )Tj EMC /Suspect <>BDC 0.345 g 6.3343 0 0 6.3001 402.61 567.12 Tm (\(INSPl )Tj EMC /Suspect <>BDC 0.114 g /T1_4 1 Tf 0 Tc 7.3001 0 0 7.3001 428.55 567.12 Tm (a)Tj 0.435 g 0.579 0 Td (: )Tj EMC ET BT 0.176 g /T1_1 1 Tf -0.0124 Tc 6.3001 0 0 6.3001 437.26 567.12 Tm (WAL)Tj 0.345 g 0 Tc 2.268 0 Td (L )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.0294 Tc 6.3001 0 0 6.3001 457.3258 567.12 Tm (\(INS )Tj EMC /Suspect <>BDC 0.05 Tc 7.022 0 0 6.3001 470.72 567.12 Tm (PI )Tj EMC /Suspect <>BDC 0.263 g /T1_6 1 Tf 0 Tc 13.2 0 0 13.2 483.99 567.12 Tm (\225)Tj 0.435 g 0.396 0 Td (= )Tj EMC ET BT 0.345 g /T1_1 1 Tf -0.035 Tc 6.2268 0 0 6.3001 493.35 567.12 Tm (GAS )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.027 Tc 6.3001 0 0 6.3001 508.21 567.12 Tm (\(EXP\) )Tj EMC /Suspect <>BDC 0.263 g -0.0111 Tc -25.809 -5.865 Td (AIRWAY )Tj EMC /Suspect <>BDC 0.345 g -0.035 Tc 6.2621 0 0 6.3001 372.39 530.17 Tm (OPENING )Tj EMC /Suspect <>BDC 0.0137 Tc 6.3001 0 0 6.3001 452.02 530.17 Tm (PHARYNX )Tj EMC ET BT 0.263 g /T1_1 1 Tf 0.0119 Tc 6.3001 0 0 6.3001 336.8227 520.0898 Tm (NASAL )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.0088 Tc 6.3001 0 0 6.3001 387.7527 520.0898 Tm (ORAL )Tj EMC ET BT /T1_1 1 Tf -0.0071 Tc 6.3001 0 0 6.3001 434.26 520.0898 Tm (NASAL )Tj ET BT /Suspect <>BDC 0.345 g /T1_1 1 Tf -0.0088 Tc 6.3001 0 0 6.3001 483.2685 519.611 Tm (ORAL )Tj EMC /Suspect <>BDC 0.263 g -0.035 Tc 6.1209 0 0 6.3001 325.79 511.44 Tm (NORM )Tj EMC /Suspect <>BDC -0.0097 Tc 6.3001 0 0 6.3001 356.07 511.44 Tm (CF )Tj EMC /Suspect <>BDC -0.035 Tc 5.9555 0 0 6.3001 376.19 510.97 Tm (NORM )Tj EMC /Suspect <>BDC -0.0097 Tc 6.3001 0 0 6.3001 403.59 510.97 Tm (CF )Tj EMC /Suspect <>BDC -0.035 Tc 5.9555 0 0 6.3001 423.71 510.97 Tm (NORM )Tj EMC /Suspect <>BDC 6.0475 0 0 6.3001 452.07 510.97 Tm (CF )Tj EMC /Suspect <>BDC 0.176 g 6.1209 0 0 6.3001 471.23 510.49 Tm (NORM )Tj EMC /Suspect <>BDC 0.345 g -0.0097 Tc 6.3001 0 0 6.3001 499.11 510.49 Tm (CF )Tj EMC ET BT 0.435 g /T1_0 1 Tf 0 Tc 12.4 0 0 12.4 326.25 460.09 Tm (-)Tj 0.263 g 0.89 0 Td (-)Tj 0.435 g 0.05 Tc 22.8902 0 0 12 352.05 460.56 Tm (--)Tj 0.655 g 23.5839 0 0 18.2001 375.08 459.12 Tm (--)Tj 0.572 g 24.9712 0 0 15.4 399.54 459.61 Tm (--)Tj ET BT /Suspect <>BDC 0.345 g /T1_1 1 Tf 27.6111 0 0 5.2 469.24 461.53 Tm (,-)Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 23.4736 0 0 18.2001 422.84 454.81 Tm (r-)Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf -0.0322 Tc 11.1 0 0 11.1 447.54 459.61 Tm (.----)Tj EMC /Suspect <>BDC 0.572 g 0.05 Tc 17.9132 0 0 8.9 493.96 460.56 Tm (,--)Tj EMC /Suspect <>BDC 0.263 g 0 Tc 15.6 0 0 15.6 326.14 448.56 Tm (+ )Tj EMC /Suspect <>BDC 15.4 0 0 15.4 375.59 448.09 Tm (+ )Tj EMC /Suspect <>BDC 0.176 g 11.1 0 0 11.1 446.7 452.41 Tm (+ )Tj EMC /Suspect <>BDC 0.263 g -0.035 Tc 7.7182 0 0 8.5 470.3 453.84 Tm ('!' )Tj EMC /Suspect <>BDC 0.176 g /T1_0 1 Tf 0 Tc 14.2 0 0 14.2 494.65 452.41 Tm (\225 )Tj EMC ET BT 0.435 g /T1_1 1 Tf 11 0 0 11 495.7 447.12 Tm (' )Tj ET BT /Suspect <>BDC 0.345 g /T1_0 1 Tf 14.1 0 0 14.1 351.77 442.81 Tm (+ )Tj EMC /Suspect <>BDC 0.263 g /T1_1 1 Tf 22.4 0 0 22.4 398.53 440.41 Tm (\225 )Tj EMC /Suspect <>BDC 0.498 g 4.9001 0 0 4.9001 430.91 449.05 Tm (I )Tj EMC /Suspect <>BDC 0.345 g 8.5 0 0 8.5 400.09 438.97 Tm (I )Tj EMC ET BT 0.263 g /T1_1 1 Tf -0.035 Tc 9.2417 0 0 19.3 429.37 445.69 Tm (,. )Tj ET BT /Suspect <>BDC 0.498 g /T1_1 1 Tf 0 Tc 6.3001 0 0 6.3001 454.87 439.44 Tm (I )Tj EMC ET BT 0.263 g /T1_4 1 Tf 11.6 0 0 11.6 453.48 430.33 Tm (T )Tj ET BT /Suspect <>BDC 0.345 g /T1_1 1 Tf 7.2 0 0 7.2 478.84 423.61 Tm (I )Tj EMC /Suspect <>BDC 0.263 g 0.05 Tc 9.2635 0 0 7.8001 477.37 416.89 Tm (!' )Tj EMC /Suspect <>BDC 0.435 g 0 Tc 6.3001 0 0 6.3001 501.91 413.05 Tm (I )Tj EMC /Suspect <>BDC 0.263 g 28 0 0 28 381.64 395.76 Tm (\225 )Tj EMC /Suspect <>BDC 19.5 0 0 19.5 460.75 392.89 Tm (f )Tj EMC /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 8.1734 0 0 8.8 500.85 405.84 Tm (!' )Tj EMC /Suspect <>BDC /T1_1 1 Tf 14.8582 0 0 16 333.41 390.97 Tm ('+ )Tj EMC /Suspect <>BDC 0.345 g 0 Tc 5.5001 0 0 5.5001 358.89 401.05 Tm (I )Tj EMC /Suspect <>BDC 6.3001 0 0 6.3001 366.55 400.56 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 14.4 0 0 14.4 405.84 395.28 Tm (+ )Tj EMC /Suspect <>BDC 0.263 g /T1_5 1 Tf 12.4 0 0 12.4 413.5 395.28 Tm (l )Tj EMC /Suspect <>BDC /T1_3 1 Tf 9.8 0 0 9.8 508.9 398.16 Tm (L )Tj EMC /Suspect <>BDC 0.176 g /T1_1 1 Tf 15.6 0 0 15.6 357.39 392.89 Tm (" )Tj EMC ET BT /T1_1 1 Tf 29.7001 0 0 29.7001 364.96 392.89 Tm (. )Tj 0.572 g 12.7 0 0 12.7 383.18 395.28 Tm (. )Tj ET BT /Suspect <>BDC 0.345 g /T1_1 1 Tf 12.7 0 0 12.7 389.5554 395.28 Tm (+ )Tj EMC ET BT /T1_1 1 Tf 10.9 0 0 10.9 437.49 395.76 Tm (; )Tj ET BT /Suspect <>BDC 0.263 g /T1_0 1 Tf 17.9 0 0 17.9 485.07 387.12 Tm (' )Tj EMC /Suspect <>BDC 0.498 g /T1_1 1 Tf 4.8001 0 0 4.8001 358.91 392.89 Tm (I )Tj EMC /Suspect <>BDC 0.435 g 1.7 0 Td (I )Tj EMC ET BT 0.345 g /T1_0 1 Tf 8.8 0 0 8.8 414.62 390 Tm (' )Tj ET BT /Suspect <>BDC 0.263 g /T1_1 1 Tf 6.3001 0 0 6.3001 509.59 393.37 Tm (I )Tj EMC /Suspect <>BDC 0.176 g -29.627 -3.657 Td (\225)Tj 0.345 g 0.05 Tc 6.3296 0 0 6.3001 328.22 370.33 Tm (\225GAS )Tj EMC /Suspect <>BDC 0.263 g 6.7728 0 0 6.3001 348.36 370.33 Tm (\(EXP\) )Tj EMC /Suspect <>BDC 0 Tc 6.3001 0 0 6.3001 376.32 370.33 Tm (Y)Tj 0.435 g 0.05 Tc 7.5369 0 0 6.3001 380.52 370.33 Tm (\225G)Tj 0.263 g 6.4615 0 0 6.3001 389.77 370.33 Tm (AS\(INSP\) )Tj EMC /Suspect <>BDC 0.114 g 0 Tc 6.3001 0 0 6.3001 430.46 370.33 Tm (\225)Tj 0.263 g 0.05 Tc 6.3296 0 0 6.3001 435.26 370.33 Tm (\225GAS )Tj EMC /Suspect <>BDC 0.345 g 6.4669 0 0 6.3001 455.41 370.33 Tm (\(INPUT\) )Tj EMC /Suspect <>BDC 0.263 g -0.0263 Tc 6.3001 0 0 6.3001 346.57 335.76 Tm (AIRWAY )Tj EMC /Suspect <>BDC 0.345 g -0.035 Tc 6.0424 0 0 6.3001 373.36 335.76 Tm (OPENING )Tj EMC /Suspect <>BDC 0.263 g -0.0244 Tc 6.3001 0 0 6.3001 453.46 335.28 Tm (PHARYNX )Tj EMC ET BT /T1_1 1 Tf 0.031 Tc 6.3001 0 0 6.3001 337.2988 326.1575 Tm (NASAL )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.0088 Tc 6.3001 0 0 6.3001 388.7076 326.1575 Tm (ORAL )Tj EMC ET BT /T1_1 1 Tf -0.0071 Tc 6.3001 0 0 6.3001 435.2149 326.1575 Tm (NASAL )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.0342 Tc 6.3001 0 0 6.3001 484.2234 325.6849 Tm (ORAL )Tj EMC /Suspect <>BDC -0.035 Tc 6.1209 0 0 6.3001 326.75 316.56 Tm (NORM )Tj EMC /Suspect <>BDC /T1_0 1 Tf -0.0347 Tc 7 0 0 7 357.05 317.05 Tm (CF )Tj EMC /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 6.2863 0 0 6.3001 376.18 317.05 Tm (NORM )Tj EMC /Suspect <>BDC /T1_0 1 Tf 6.59 0 0 7 405.05 317.05 Tm (CF )Tj EMC /Suspect <>BDC /T1_1 1 Tf 5.9555 0 0 6.3001 424.19 316.56 Tm (NORM )Tj EMC /Suspect <>BDC 6.0475 0 0 6.3001 453.03 316.56 Tm (CF )Tj EMC ET BT 0.345 g /T1_1 1 Tf 5.9555 0 0 6.3001 472.19 316.56 Tm (NORM )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0347 Tc 7 0 0 7 500.09 316.09 Tm (CF )Tj EMC /Suspect <>BDC 0.263 g /T1_1 1 Tf 0 Tc 26.2001 0 0 26.2001 423.91 300.25 Tm (\225)Tj 0.655 g 0.3 0 Td (\267 )Tj EMC /Suspect <>BDC 0.263 g /T1_7 1 Tf -0.035 Tc 5.2783 0 0 9.6 448.26 305.53 Tm (.L )Tj EMC /Suspect <>BDC 0.176 g /T1_1 1 Tf 8.2465 0 0 18.4 472.1 307.44 Tm (.. )Tj EMC /Suspect <>BDC /T1_0 1 Tf 0 Tc 14.1 0 0 14.1 496.09 303.12 Tm (\225 )Tj EMC /Suspect <>BDC 0.572 g 12.2 0 0 12.2 329.62 298.33 Tm (' )Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf 12 0 0 12 353.91 294 Tm (I )Tj EMC /Suspect <>BDC 0.572 g 6.3001 0 0 6.3001 378.55 300.72 Tm (I )Tj EMC ET BT /T1_5 1 Tf 12.3 0 0 12.3 425.6 297.84 Tm (')Tj 0.345 g 0.476 0 Td (T )Tj ET BT /Suspect <>BDC 0.572 g /T1_1 1 Tf 11.3 0 0 11.3 449.62 296.41 Tm (' )Tj EMC /Suspect <>BDC 0.435 g 6.3001 0 0 6.3001 473.59 303.12 Tm (I )Tj EMC /Suspect <>BDC 0.498 g 10.1 0 0 10.1 497 298.33 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 14 0 0 14 328.1 296.41 Tm (\225 )Tj EMC /Suspect <>BDC 0.572 g 4.6 0 0 4.6 329.16 294.97 Tm (I )Tj EMC /Suspect <>BDC 0.176 g -0.035 Tc 9.2774 0 0 19.2001 377.03 295.93 Tm (.. )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf 0 Tc 14.2 0 0 14.2 353.05 286.81 Tm (\225 )Tj EMC /Suspect <>BDC 0.572 g /T1_1 1 Tf 3.9001 0 0 3.9001 378.62 292.56 Tm (I )Tj EMC /Suspect <>BDC 0.345 g 12.1 0 0 12.1 402.39 286.81 Tm (I )Tj EMC /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 6.7776 0 0 12.8 454.42 285.84 Tm (... )Tj EMC /Suspect <>BDC 0.572 g /T1_1 1 Tf 0 Tc 8.8 0 0 8.8 354 282.49 Tm (I )Tj EMC /Suspect <>BDC 0.176 g /T1_0 1 Tf 15.1 0 0 15.1 401.04 279.61 Tm (\225 )Tj EMC ET BT 0.572 g /T1_1 1 Tf 15.6 0 0 15.6 455.8 273.37 Tm (' )Tj ET BT /Suspect <>BDC 0.263 g /T1_1 1 Tf 15.9 0 0 15.9 402.28 270.49 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 19.2001 0 0 19.2001 479.47 254.65 Tm (I )Tj EMC /Suspect <>BDC 13.8 0 0 13.8 478.37 243.13 Tm (" )Tj EMC /Suspect <>BDC 0.498 g 18.5 0 0 18.5 502.53 238.8 Tm (I )Tj EMC /Suspect <>BDC 0.263 g 17.9 0 0 17.9 479.5 235.93 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 13.8 0 0 13.8 501.89 227.29 Tm (" )Tj EMC /Suspect <>BDC 0.435 g 9.4 0 0 9.4 384.22 217.69 Tm (I )Tj EMC /Suspect <>BDC 0.176 g 18.5 0 0 18.5 502.53 218.65 Tm (I )Tj EMC /Suspect <>BDC 14.6 0 0 14.6 382.84 206.65 Tm (" )Tj EMC /Suspect <>BDC 0.345 g 6.3001 0 0 6.3001 384.31 207.61 Tm (I )Tj EMC /Suspect <>BDC 0.572 g 3.9001 0 0 3.9001 408.38 210.49 Tm (I )Tj EMC /Suspect <>BDC 0.176 g /T1_0 1 Tf -0.035 Tc 12.3044 0 0 13.3 334.33 198.97 Tm ("+ )Tj EMC /Suspect <>BDC 0.263 g /T1_1 1 Tf 0 Tc 4.9001 0 0 4.9001 360.35 203.76 Tm (I )Tj EMC /Suspect <>BDC 0.435 g 7.8001 0 0 7.8001 366.99 203.76 Tm (I )Tj EMC /Suspect <>BDC 0.263 g /T1_4 1 Tf -0.035 Tc 10.9835 0 0 14.4 406.92 199.44 Tm (r+ )Tj EMC /Suspect <>BDC 0.345 g /T1_1 1 Tf 0 Tc 6.6 0 0 6.6 462.54 203.76 Tm (I )Tj EMC /Suspect <>BDC 0.435 g 6.3001 0 0 6.3001 509.73 204.25 Tm (t )Tj EMC /Suspect <>BDC 0.263 g /T1_0 1 Tf -0.035 Tc 12.9518 0 0 20 358.29 201.37 Tm (.,., )Tj EMC /Suspect <>BDC 0.176 g /T1_1 1 Tf 0 Tc 22 0 0 22 389.95 187.44 Tm (' )Tj EMC /Suspect <>BDC 0.263 g /C0_0 1 Tf 3.84 0 0 7.2 438.24 198.49 Tm <007E0020>Tj EMC /Suspect <>BDC 0.176 g /T1_1 1 Tf 21.5 0 0 21.5 461.42 193.21 Tm (\225 )Tj EMC /Suspect <>BDC 13.1 0 0 13.1 485.08 198.49 Tm (\225 )Tj EMC /Suspect <>BDC 12 0 0 12 508.61 197.52 Tm (\225 )Tj EMC /Suspect <>BDC 0.05 Tc 13.9471 0 0 6.3001 323.63 175.44 Tm (.. )Tj EMC ET BT 0.345 g /T1_1 1 Tf -0.0086 Tc 6.3001 0 0 6.3001 333.02 175.44 Tm (GAS )Tj ET BT /Suspect <>BDC 0.263 g /T1_1 1 Tf 0.05 Tc 6.5638 0 0 6.3001 350.29 175.44 Tm (\(EXPI )Tj EMC /Suspect <>BDC 0.176 g 0 Tc 6.3001 0 0 6.3001 376.22 175.44 Tm (\225)Tj 0.435 g 0.05 Tc 7.5369 0 0 6.3001 381.48 175.44 Tm (\225G)Tj 0.263 g -0.035 Tc 6.2865 0 0 6.3001 389.77 175.44 Tm (AS )Tj EMC /Suspect <>BDC 0.0464 Tc 6.3001 0 0 6.3001 401.17 175.44 Tm (\(INSP\) )Tj EMC /Suspect <>BDC /T1_4 1 Tf 0.05 Tc 10.6012 0 0 6.2 429.96 175.44 Tm (e. )Tj EMC ET BT /T1_1 1 Tf -0.035 Tc 5.9873 0 0 6.3001 439.59 175.44 Tm (GAS )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.042 Tc 6.3001 0 0 6.3001 456.37 175.44 Tm (\(INPUT\) )Tj EMC ET BT /T1_0 1 Tf -0.0077 Tc 8.4 0 0 8.4 290.84 154.33 Tm (Fig. )Tj /T1_6 1 Tf -0.035 Tc 8.2535 0 0 8.5 307.12 154.33 Tm (5. )Tj /T1_0 1 Tf 0.0339 Tc 8.4 0 0 8.4 321.11 154.33 Tm (Upper )Tj -0.0042 Tc 3.02 0 Td (airway )Tj 0.0007 Tc 3.094 0 Td (humidification )Tj -0.018 Tc 6.279 0 Td (in )Tj 0.0061 Tc 1.15 0 Td (normal )Tj 0.0269 Tc 3.249 0 Td (and )Tj 0.05 Tc 8.8292 0 0 8.4 477.51 154.33 Tm (CF )Tj 0.001 Tc 8.4 0 0 8.4 491.4 154.33 Tm (subjects )Tj 0.0081 Tc -23.87 -1.086 Td (breathing )Tj 0.0492 Tc 4.112 0 Td (hot )Tj 0.0219 Tc 1.649 0 Td (air )Tj 0.0154 Tc 1.436 0 Td (through )Tj 0.0197 Tc 3.486 0 Td (the )Tj 0 Tc 1.544 0 Td (nose )Tj 0.0269 Tc 2.106 0 Td (and )Tj 0.0229 Tc 1.779 0 Td (mouth. )Tj -0.0141 Tc 3.248 0 Td (\(Symbols )Tj -0.0004 Tc 4.068 0 Td (represent )Tj -0.0148 Tc -23.43 -1.086 Td (mean )Tj -0.0064 Tc 2.4 0 Td (values )Tj 0.0269 Tc 2.736 0 Td (and )Tj -0.0023 Tc 1.721 0 Td (vertical )Tj 0.0196 Tc 3.261 0 Td (bars )Tj 0.0073 Tc 1.927 0 Td (span )Tj 0.0197 Tc 2.126 0 Td (the )Tj -0.0118 Tc 1.544 0 Td (range )Tj 0.0074 Tc 2.448 0 Td (for )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 7.2926 0 0 8.4 454.97 136.09 Tm (aU )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.5145 0 0 8.4 465.04 136.09 Tm (data )Tj 0.0017 Tc 8.4 0 0 8.4 482.41 136.09 Tm (points\). )Tj -0.035 Tc 8.2476 0 0 8.4 510.23 136.09 Tm (A. )Tj 0.0112 Tc 8.4 0 0 8.4 290.33 127.44 Tm (Temperature: )Tj -0.0098 Tc 6.057 0 Td (local )Tj -0.0015 Tc 2.4 0 Td (gas )Tj 0.049 Tc 1.827 0 Td (on )Tj 0.345 g 0.0143 Tc 1.544 0 Td (inspiration )Tj 0.263 g 0.0269 Tc 4.913 0 Td (and )Tj -0.0082 Tc 2.057 0 Td (on )Tj 0.345 g 0.012 Tc 1.485 0 Td (expiration, )Tj 0.263 g -0.0098 Tc 4.974 0 Td (local )Tj 0.345 g 0.0072 Tc -25.258 -1.086 Td (airway )Tj 0.0093 Tc 3.138 0 Td (surface )Tj -0.0074 Tc 3.317 0 Td (\(wall\), )Tj 0.0269 Tc 3.031 0 Td (and )Tj 0.263 g 0.0079 Tc 1.944 0 Td (inhaled )Tj 0.0271 Tc 3.371 0 Td (gas )Tj 0.345 g 0.0072 Tc 1.768 0 Td (\(input\); )Tj 0.263 g -0.035 Tc 7.8194 0 0 8.4 458.85 118.32 Tm (B. )Tj 0.0062 Tc 8.4 0 0 8.4 469.89 118.32 Tm (Water )Tj 0.0173 Tc 2.915 0 Td (vapour )Tj 0.0241 Tc -24.339 -1.029 Td (partial )Tj 0.0003 Tc 3.143 0 Td (pressure: )Tj 0.345 g -0.0098 Tc 4.105 0 Td (local )Tj 0.263 g -0.0015 Tc 2.343 0 Td (gas )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0311 Tc 8.4 0 0 8.4 385.3608 109.6764 Tm (oil )Tj EMC ET BT /T1_0 1 Tf 0.0086 Tc 8.4 0 0 8.4 397.8516 109.6764 Tm (inspiration )Tj 0.05 Tc 8.4599 0 0 8.4 438.15 109.68 Tm (and )Tj 0.345 g 0.049 Tc 8.4 0 0 8.4 454.96 109.68 Tm (on )Tj 0.263 g 0.0093 Tc 1.427 0 Td (expiration )Tj 0.05 Tc 8.4599 0 0 8.4 505.35 109.68 Tm (and )Tj -0.0016 Tc 8.4 0 0 8.4 290.33 100.57 Tm (inhaled )Tj -0.0015 Tc 3.429 0 Td (gas )Tj 0.0111 Tc 1.768 0 Td (\(input\). )Tj 0.0042 Tc 3.549 0 Td (Equilibrium )Tj 0.018 Tc 5.319 0 Td (water )Tj 0.0288 Tc 2.742 0 Td (vapour )Tj 0.0053 Tc 3.318 0 Td (pressu)Tj 0.114 g 0 Tc 2.626 0 Td (r)Tj 0.263 g 0.276 0 Td (e )Tj 0.05 Tc 8.8544 0 0 8.4 490.95 100.57 Tm (at )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 7.7578 0 0 8.4 501.99 100.57 Tm (37)Tj 0.435 g -0.0067 Tc 8.4 0 0 8.4 509.6 100.57 Tm ("C )Tj EMC ET BT 0.263 g /T1_0 1 Tf 0.0017 Tc 8.4 0 0 8.4 290.3264 91.4392 Tm (indicated )Tj -0.019 Tc 4.295 0 Td (by )Tj 0.0197 Tc 1.539 0 Td (the )Tj 0.0076 Tc 1.83 0 Td (horizontal )Tj -0.0111 Tc 4.679 0 Td (line; )Tj -0.035 Tc 8.378 0 0 8.4 413.19 91.44 Tm (C. )Tj -0.0013 Tc 8.4 0 0 8.4 425.72 91.44 Tm (Relative )Tj -0.0006 Tc 3.889 0 Td (humidity )Tj 0.0258 Tc 4.161 0 Td (\(at )Tj -0.0015 Tc 1.661 0 Td (gas )Tj 0.0043 Tc -25.823 -1.029 Td (temperature\): )Tj 0.176 g -0.024 Tc 6.108 0 Td (local )Tj 0.263 g -0.0015 Tc 2.457 0 Td (gas )Tj -0.0082 Tc 1.885 0 Td (on )Tj 0.0086 Tc 1.601 0 Td (inspiration )Tj 0.0269 Tc 4.913 0 Td (and )Tj 0.049 Tc 2.114 0 Td (on )Tj 0.012 Tc 1.542 0 Td (expiration, )Tj 0.345 g 0.0269 Tc 4.973 0 Td (and )Tj 0.263 g -0.0016 Tc -25.599 -1.086 Td (inhaled )Tj -0.0015 Tc 3.314 0 Td (gas )Tj 0.345 g 0.0029 Tc 1.654 0 Td (\(input\). )Tj ET endstream endobj 42 0 obj <>stream Hd͊zy8 >sRhF^#y 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-0.035 Tc 9.9195 0 0 10.2 218.8 728.89 Tm (in )Tj 0.0226 Tc 10.2 0 0 10.2 231.37 728.89 Tm (both )Tj 0.263 g 0.0111 Tc 2.338 0 Td (subject )Tj 0.0091 Tc -19.336 -1.082 Td (groups. )Tj ET BT /Suspect <>BDC 0.192 g /T1_0 1 Tf 0.0238 Tc 10.2 0 0 10.2 93.976 717.8536 Tm (On )Tj EMC ET BT 0.263 g /T1_0 1 Tf 0.0214 Tc 10.2 0 0 10.2 111.2752 717.8536 Tm (inspiration )Tj 0.0232 Tc 4.947 0 Td (through )Tj 0.0029 Tc 3.765 0 Td (the )Tj 0.0179 Tc 1.648 0 Td (nose )Tj 0.05 Tc 10.5727 0 0 10.2 240.38 717.85 Tm (or )Tj 0.192 g 0.033 Tc 10.2 0 0 10.2 253.9 717.85 Tm (mouth, )Tj 0.263 g 0.0265 Tc -19.2 -1.083 Td (the )Tj 0.192 g /T1_1 1 Tf 0.05 Tc 8.2169 0 0 8 75.17 706.8 Tm (PH)Tj /T1_0 1 Tf 0 Tc 6.8001 0 0 6.8001 87.32 704.41 Tm (2)Tj 10.2 0 0 10.2 91.1 706.8 Tm (o )Tj 0.263 g 0.05 Tc 10.5727 0 0 10.2 101.18 706.8 Tm (of )Tj 0.0202 Tc 10.2 0 0 10.2 113.78 706.8 Tm (pharyngeal )Tj 0.0002 Tc 5.025 0 Td (gas )Tj -0.035 Tc 9.3682 0 0 10.2 183.28 706.8 Tm (is )Tj 0.0115 Tc 10.2 0 0 10.2 193.35 706.8 Tm (lower )Tj 0.192 g -0.0079 Tc 2.73 0 Td (in )Tj 0.05 Tc 11.1325 0 0 10.2 233.16 706.8 Tm (CF )Tj 0.263 g 0.0145 Tc 10.2 0 0 10.2 250.9 706.8 Tm (subjects )Tj 0.0235 Tc -18.906 -1.035 Td (than )Tj 0.0391 Tc 2.488 0 Td (in )Tj 0.192 g 0.0182 Tc 1.513 0 Td (normal )Tj 0.263 g -0.0009 Tc 3.611 0 Td (subjects. )Tj 0.024 Tc 4.19 0 Td (\(Although )Tj 0.0029 Tc 4.998 0 Td (the )Tj 0.0167 Tc 1.929 0 Td (trend )Tj -0.035 Tc 10.1489 0 0 10.2 278.32 696.24 Tm (is )Tj 0.0344 Tc 10.2 0 0 10.2 57.5 685.21 Tm (apparent, )Tj 0.0029 Tc 4.384 0 Td (the )Tj 0.192 g 0.0301 Tc 1.601 0 Td (number )Tj 0.263 g 0.05 Tc 11.1292 0 0 10.2 154.45 685.21 Tm (of )Tj 0.0447 Tc 10.2 0 0 10.2 166.94 685.21 Tm (data )Tj 0.0308 Tc 2.176 0 Td (points )Tj -0.035 Tc 9.3682 0 0 10.2 219.28 685.21 Tm (is )Tj 0.05 Tc 10.4827 0 0 10.2 228.95 685.21 Tm (not )Tj -0.0085 Tc 10.2 0 0 10.2 246.58 685.21 Tm (sufficient )Tj 0.0253 Tc -18.482 -1.082 Td (to )Tj 0.0068 Tc 1.45 0 Td (establish )Tj 0.0115 Tc 4.232 0 Td (statistical )Tj -0.0014 Tc 4.565 0 Td (significance.\) )Tj -0.0228 Tc 6.035 0 Td (As )Tj 0.0242 Tc 1.729 0 Td (shown )Tj -0.0079 Tc 3.394 0 Td (in )Tj -0.0105 Tc -21.462 -1.035 Td (figure )Tj -0.035 Tc 10.1796 0 0 10.2 85.73 663.61 Tm (SC, )Tj 0.0029 Tc 10.2 0 0 10.2 104.62 663.61 Tm (the )Tj 0.0232 Tc 1.64 0 Td (groups )Tj 0.0115 Tc 3.245 0 Td (exhibit )Tj -0.0085 Tc 3.257 0 Td (no )Tj 0.0341 Tc 1.404 0 Td (great )Tj 0.192 g -0.0052 Tc 2.493 0 Td (differences )Tj -0.0079 Tc 4.802 0 Td (in )Tj 0.263 g 0.0029 Tc -21.406 -1.083 Td (the )Tj 0.192 g 0.05 Tc 10.6986 0 0 10.2 73.87 652.56 Tm (RH )Tj 0.263 g 11.1292 0 0 10.2 91.57 652.56 Tm (of )Tj 0.0138 Tc 10.2 0 0 10.2 103.09 652.56 Tm (expired )Tj 0.0002 Tc 3.343 0 Td (gas )Tj 0.044 Tc 1.599 0 Td (at )Tj 0.0383 Tc 1.093 0 Td (both )Tj 0.0138 Tc 2.209 0 Td (measurement )Tj 0.0217 Tc 5.734 0 Td (locations )Tj 0.05 Tc 10.5727 0 0 10.2 57.5 641.53 Tm [(or )-38(of )]TJ 0.0002 Tc 10.2 0 0 10.2 82.95 641.53 Tm (gas )Tj -0.0079 Tc 1.742 0 Td (in )Tj 0.0265 Tc 1.182 0 Td (the )Tj 0.0202 Tc 1.651 0 Td (pharynx )Tj 0.0257 Tc 3.8 0 Td (during )Tj 0.0214 Tc 3.155 0 Td (inspiration )Tj 0.0311 Tc 4.9 0 Td (through )Tj 0.0265 Tc -18.918 -1.035 Td (the )Tj 0.0236 Tc 1.553 0 Td (mouth. )Tj 0.192 g 0.0187 Tc 3.338 0 Td (But )Tj 0.263 g 0.0192 Tc 1.735 0 Td (for )Tj 0.192 g 0.0458 Tc 1.563 0 Td (hot )Tj 0.263 g 0.0202 Tc 1.685 0 Td (air )Tj 0.0063 Tc 1.414 0 Td (inspired )Tj 0.0389 Tc 3.582 0 Td (through )Tj 0.0265 Tc 3.671 0 Td (the )Tj -0.002 Tc 1.554 0 Td (nose, )Tj 0.0265 Tc -20.095 -1.083 Td (the )Tj 0.192 g 0.05 Tc 10.6986 0 0 10.2 73.39 619.92 Tm (RH )Tj 0.263 g 10.7518 0 0 10.2 91.57 619.92 Tm (at )Tj 0.0265 Tc 10.2 0 0 10.2 102.22 619.92 Tm (the )Tj 0.0202 Tc 1.557 0 Td (pharynx )Tj -0.035 Tc 10.1489 0 0 10.2 155.44 619.92 Tm (is )Tj 0.0078 Tc 10.2 0 0 10.2 165.11 619.92 Tm (higher )Tj -0.0079 Tc 2.817 0 Td (in )Tj 0.192 g 0.0182 Tc 1.089 0 Td (normal )Tj 0.263 g 0.05 Tc 10.2803 0 0 10.2 238.05 619.92 Tm (than )Tj -0.0079 Tc 10.2 0 0 10.2 260.08 619.92 Tm (in )Tj 0.05 Tc 10.7486 0 0 10.2 270.61 619.92 Tm (CF )Tj 0.005 Tc 10.2 0 0 10.2 56.98 608.89 Tm (subjects. )Tj 0.192 g -0.0276 Tc 10.6 0 0 10.6 148.75 580.09 Tm (Discussion )Tj 0.263 g /T1_2 1 Tf -0.0138 Tc 9.9 0 0 9.9 57.2 562.8 Tm (Flow )Tj 0.0302 Tc 2.362 0 Td (and )Tj 0.192 g 0.0045 Tc 1.843 0 Td (duration )Tj /T1_0 1 Tf 0.0069 Tc 10.2 0 0 10.2 67.16 545.53 Tm (When )Tj 0.0227 Tc 2.773 0 Td (instantaneous )Tj 0.263 g -0.035 Tc 10.1707 0 0 10.2 156.85 545.53 Tm (flow )Tj 0.0382 Tc 10.2 0 0 10.2 178.44 545.53 Tm (\(or )Tj 0.0002 Tc 1.509 0 Td (gas )Tj -0.0019 Tc 1.654 0 Td (velocity\) )Tj 0.0311 Tc 3.859 0 Td (through )Tj 0.0029 Tc -18.918 -1.083 Td (the )Tj 0.0173 Tc 1.639 0 Td (airways )Tj 0.009 Tc 3.578 0 Td (is )Tj 0.0047 Tc 1.082 0 Td (increased, )Tj 0.0029 Tc 4.571 0 Td (the )Tj 0.0348 Tc 1.648 0 Td (rate )Tj 0.05 Tc 11.1292 0 0 10.2 205.33 534.48 Tm (of )Tj 0.0231 Tc 10.2 0 0 10.2 217.91 534.48 Tm (water )Tj 0.037 Tc 2.721 0 Td (and )Tj 0.192 g 0.0274 Tc 2.032 0 Td (heat )Tj 0.263 g 0.0216 Tc -20.519 -1.082 Td (transfer )Tj 0.0038 Tc 3.862 0 Td (between )Tj 0.0265 Tc 3.997 0 Td (the )Tj 0.0002 Tc 1.923 0 Td (gas )Tj 0.037 Tc 1.975 0 Td (and )Tj 0.0106 Tc 2.22 0 Td (mucosal )Tj 0.0098 Tc 4.035 0 Td (surface )Tj 0.192 g -0.035 Tc 10.1489 0 0 10.2 277.36 523.44 Tm (is )Tj 0.263 g 0.0067 Tc 10.2 0 0 10.2 56.53 512.89 Tm (expected )Tj 0.0253 Tc 3.962 0 Td (to )Tj 0.0031 Tc 1.171 0 Td (increase. )Tj ET BT /Suspect <>BDC 0.192 g /T1_0 1 Tf 0.0316 Tc 10.2 0 0 10.2 148.7074 512.89 Tm (Over )Tj EMC ET BT 0.263 g /T1_0 1 Tf 0.0265 Tc 10.2 0 0 10.2 173.7484 512.89 Tm (the )Tj 0.0218 Tc 1.601 0 Td (range )Tj 0.05 Tc 11.1292 0 0 10.2 216.85 512.89 Tm (of )Tj 0.0156 Tc 10.2 0 0 10.2 228.85 512.89 Tm (experimental )Tj 0.0207 Tc -16.893 -1.083 Td (conditions )Tj 0.0153 Tc 4.658 0 Td (examined, )Tj 0.192 g -0.0003 Tc 4.669 0 Td (however)Tj 0.349 g 0 Tc 3.468 0 Td (, )Tj 0.263 g 0.0029 Tc 0.625 0 Td (the )Tj -0.0088 Tc 1.544 0 Td (effects )Tj 0.05 Tc 11.6856 0 0 10.2 238.93 501.84 Tm (of )Tj -0.035 Tc 10.1707 0 0 10.2 251.41 501.84 Tm (flow )Tj 0.05 Tc 10.2564 0 0 10.2 273.02 501.84 Tm (on )Tj 0.0237 Tc 10.2 0 0 10.2 56.55 490.81 Tm (gas )Tj 0.0269 Tc 1.654 0 Td (temperature )Tj 0.192 g -0.0168 Tc 5.355 0 Td (\(T\) )Tj 0.263 g 0.037 Tc 1.602 0 Td (and )Tj 0.192 g 0 Tc 1.84 0 Td (H)Tj 6.8001 0 0 6.8001 171.8 488.89 Tm (2)Tj 10.2 0 0 10.2 175.57 490.81 Tm (0 )Tj 0.263 g 0.0314 Tc 1.048 0 Td (partial )Tj 0.192 g 0.0163 Tc 3.059 0 Td (pressure )Tj 0.263 g -0.035 Tc 10.0914 0 0 10.2 255.24 490.81 Tm (\(PH)Tj 0 Tc 6.8001 0 0 6.8001 271.16 488.41 Tm (2)Tj 0.0345 Tc 10.2 0 0 10.2 274.94 490.81 Tm (o\) )Tj 0.0313 Tc -21.412 -1.035 Td (are )Tj -0.035 Tc 10.1035 0 0 10.2 73.35 480.25 Tm (less )Tj 0.04 Tc 10.2 0 0 10.2 91.12 480.25 Tm (important )Tj 0.0392 Tc 4.571 0 Td (than )Tj 0.0029 Tc 2.259 0 Td (the )Tj 0.0249 Tc 1.592 0 Td (condition )Tj 0.05 Tc 10.5727 0 0 10.2 221.18 480.25 Tm (of )Tj 0.0265 Tc 10.2 0 0 10.2 233.26 480.25 Tm (the )Tj 0.013 Tc 1.641 0 Td (inspired )Tj -0.0048 Tc -18.966 -1.082 Td (gas. )Tj 0.192 g 0.0037 Tc 1.976 0 Td (Typically, )Tj 0.263 g 0.0265 Tc 4.572 0 Td (the )Tj 0.192 g 0.0488 Tc 1.698 0 Td (peak )Tj 0.263 g -0.035 Tc 10.1707 0 0 10.2 165.01 469.21 Tm (flow )Tj 0.0218 Tc 10.2 0 0 10.2 187.19 469.21 Tm (range )Tj 0.0427 Tc 2.673 0 Td (for )Tj 0.05 Tc 10.5338 0 0 10.2 231.26 469.21 Tm (our )Tj 0.0078 Tc 10.2 0 0 10.2 250.42 469.21 Tm (subjects )Tj 0.0007 Tc -19 -1.083 Td (varied )Tj -0.0022 Tc 2.921 0 Td (by )Tj 0 Tc 1.354 0 Td (a )Tj 0.0198 Tc 0.799 0 Td (factor )Tj 0.05 Tc 11.1292 0 0 10.2 136.69 458.16 Tm (of )Tj 0.0192 Tc 10.2 0 0 10.2 149.26 458.16 Tm (three )Tj 0.05 Tc 10.5727 0 0 10.2 174.14 458.16 Tm (or )Tj 0.0103 Tc 10.2 0 0 10.2 186.61 458.16 Tm (four, )Tj 0.0232 Tc 2.354 0 Td (corresponding )Tj 0.0253 Tc 6.361 0 Td (to )Tj 0.05 Tc 10.2654 0 0 10.2 56.06 447.12 Tm (an )Tj 0.0098 Tc 10.2 0 0 10.2 73.34 447.12 Tm (average )Tj -0.035 Tc 10.1707 0 0 10.2 112.21 447.12 Tm (flow )Tj 0.0382 Tc 10.2 0 0 10.2 136.68 447.12 Tm (\(or )Tj 0.014 Tc 1.939 0 Td (ventilation\) )Tj 0.05 Tc 11.1292 0 0 10.2 211.57 447.12 Tm (of )Tj 10.5607 0 0 10.2 226.45 447.12 Tm (about )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0346 Tc 10.2 0 0 10.2 258.85 447.12 Tm (10-30 )Tj EMC /Suspect <>BDC 0.192 g 0.0337 Tc -19.825 -1.035 Td (/\267rnin)Tj 0.349 g 0 Tc 2.435 0 Td (-)Tj /T1_1 1 Tf 6.2 0 0 6.2 87.64 439.93 Tm (1)Tj 0.715 -0.544 Td (\225 )Tj EMC ET BT 0.192 g /T1_0 1 Tf 0.05 Tc 10.5034 0 0 10.2 97.37 436.56 Tm (In )Tj 0.263 g 0.0061 Tc 10.2 0 0 10.2 110.86 436.56 Tm (this )Tj 0.0158 Tc 1.835 0 Td (ventilation )Tj 0.192 g 0.0051 Tc 4.848 0 Td (range, )Tj 0.263 g -0.035 Tc 9.7302 0 0 10.2 208.28 436.56 Tm (McFADDEN )Tj /T1_2 1 Tf 0.05 Tc 10.923 0 0 9.9 261.98 436.56 Tm (eta/. )Tj /T1_0 1 Tf -0.035 Tc 9.5041 0 0 10.2 55.93 425.53 Tm ([8] )Tj 0.0237 Tc 10.2 0 0 10.2 69.97 425.53 Tm (found )Tj 0.05 Tc 10.215 0 0 10.2 99.34 425.53 Tm (that )Tj 0.0265 Tc 10.2 0 0 10.2 119.98 425.53 Tm (the )Tj 0.0269 Tc 1.647 0 Td (temperature )Tj 0.044 Tc 5.404 0 Td (at )Tj 0.0265 Tc 1.137 0 Td (the )Tj 0.0098 Tc 1.64 0 Td (glottis )Tj 0.016 Tc 2.917 0 Td (changes )Tj -0.035 Tc 10.0482 0 0 10.2 56.65 414.49 Tm (by )Tj 0.05 Tc 10.3614 0 0 10.2 72.85 414.49 Tm (about )Tj 0 Tc 10.2 0 0 10.2 105.05 414.49 Tm (I )Tj 0.349 g 0.0473 Tc 0.417 0 Td (\260C)Tj 0.192 g 0 Tc 1.123 0 Td (. )Tj 0.05 Tc 10.4937 0 0 10.2 129.51 414.49 Tm (Th)Tj 0.067 g 0 Tc 10.2 0 0 10.2 142 414.49 Tm (i)Tj 0.263 g 0.229 0 Td (s )Tj -0.035 Tc 9.3682 0 0 10.2 155.44 414.49 Tm (is )Tj 0 Tc 10.2 0 0 10.2 167.9 414.49 Tm (a )Tj -0.0006 Tc 1.185 0 Td (relatively )Tj 0.0067 Tc 4.411 0 Td (small )Tj 0.0217 Tc 2.827 0 Td (change )Tj 0.025 Tc -19.388 -1.083 Td (compared )Tj 0.0253 Tc 4.431 0 Td (to )Tj 0.0265 Tc 1.129 0 Td (the )Tj 0.192 g -0.0052 Tc 1.545 0 Td (differences )Tj 0.263 g 0.028 Tc 4.671 0 Td (produced )Tj -0.0022 Tc 4.234 0 Td (by )Tj 0.0265 Tc 1.268 0 Td (the )Tj 0.192 g 0.0183 Tc 1.498 0 Td (different )Tj 0.0063 Tc -18.775 -1.081 Td (inspired )Tj 0.263 g -0.0079 Tc 3.67 0 Td (gases )Tj 0.05 Tc 11.1292 0 0 10.2 118.93 392.41 Tm (of )Tj 10.5338 0 0 10.2 130.94 392.41 Tm (our )Tj 0.0267 Tc 10.2 0 0 10.2 148.69 392.41 Tm (exper)Tj 0.067 g 0 Tc 2.309 0 Td (i)Tj 0.263 g 0.0007 Tc 0.288 0 Td (ments. )Tj 0.0296 Tc -10.684 -1.036 Td (Furthermore, )Tj -0.0079 Tc 6.302 0 Td (in )Tj 0.0201 Tc 1.453 0 Td (studies )Tj 0.05 Tc 11.1292 0 0 10.2 181.81 381.84 Tm (of )Tj 0.0219 Tc 10.2 0 0 10.2 197.77 381.84 Tm (bronchoconstriction )Tj 0.0351 Tc -13.94 -1.081 Td (during )Tj 0.0439 Tc 3.247 0 Td (dry )Tj 0.0202 Tc 1.976 0 Td (air )Tj 0.0194 Tc 1.658 0 Td (breathing, )Tj -0.035 Tc 8.4063 0 0 10.2 174.19 370.81 Tm (ESHENBACHER )Tj 0.05 Tc 10.3398 0 0 10.2 237.97 370.81 Tm (and )Tj -0.035 Tc 9.0377 0 0 10.2 259.52 370.81 Tm (SHEP\255)Tj 8.2965 0 0 8.5 56.12 359.76 Tm (PARD )Tj 0.192 g 9.7536 0 0 10.2 81.84 359.76 Tm ([12] )Tj 0.263 g 0.0237 Tc 10.2 0 0 10.2 101.65 359.76 Tm (found )Tj 0.0045 Tc 2.868 0 Td (significant )Tj 0.016 Tc 4.663 0 Td (changes )Tj -0.0079 Tc 3.72 0 Td (in )Tj 0.0139 Tc 1.222 0 Td (airway )Tj 0.192 g -0.0186 Tc 3.256 0 Td (resis\255)Tj 0.263 g 0.0153 Tc -20.189 -1.082 Td (tance )Tj 0.192 g 0.0014 Tc 3.059 0 Td (mainly )Tj 0.0171 Tc 3.672 0 Td (when )Tj 0.263 g 0.0029 Tc 3.152 0 Td (the )Tj 0.0158 Tc 2.118 0 Td (ventilation )Tj -0.0059 Tc 5.309 0 Td (exceeds )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 9.8266 0 0 10.2 273.97 348.72 Tm (30 )Tj EMC /Suspect <>BDC 0.192 g /T1_3 1 Tf 0 Tc 10.4 0 0 10.4 55.51 338.16 Tm (I )Tj EMC /Suspect <>BDC 0.067 g /T1_0 1 Tf 10.2 0 0 10.2 59.79 338.16 Tm (\267)Tj 0.263 g 0.0488 Tc 0.301 0 Td (min )Tj EMC /Suspect <>BDC 0.349 g 0 Tc 1.778 0 Td (-)Tj 6.5001 0 0 6.5001 87.14 341.53 Tm (1)Tj 0.609 -0.518 Td (\225 )Tj EMC ET BT 0.263 g /T1_0 1 Tf 0.0068 Tc 10.2 0 0 10.2 96.77 338.16 Tm (Since )Tj 0.0061 Tc 2.605 0 Td (this )Tj 0.0136 Tc 1.835 0 Td (value )Tj -0.035 Tc 10.1489 0 0 10.2 168.4 338.16 Tm (is )Tj 0.0478 Tc 10.2 0 0 10.2 177.98 338.16 Tm (about )Tj 0.0029 Tc 2.831 0 Td (the )Tj 0.192 g 0.0311 Tc 1.602 0 Td (upper )Tj 0.0149 Tc 2.768 0 Td (limit )Tj 0.263 g 0.05 Tc 11.1292 0 0 10.2 274.45 338.16 Tm (of )Tj 0.0098 Tc 10.2 0 0 10.2 55.58 327.12 Tm (average )Tj 0.192 g -0.035 Tc 10.1707 0 0 10.2 91.57 327.12 Tm (flow )Tj 0.263 g 9.9195 0 0 10.2 113.2 327.12 Tm (in )Tj 0.05 Tc 10.5338 0 0 10.2 124.22 327.12 Tm (our )Tj 0.0152 Tc 10.2 0 0 10.2 142.42 327.12 Tm (studies, )Tj -0.0202 Tc 3.488 0 Td (it )Tj 0.192 g -0.035 Tc 10.1489 0 0 10.2 187.12 327.12 Tm (is )Tj 0.263 g 0.0455 Tc 10.2 0 0 10.2 197.27 327.12 Tm (not )Tj 0.0214 Tc 1.742 0 Td (unreasonable )Tj 0.0253 Tc 5.88 0 Td (to )Tj 0.0098 Tc -21.515 -1.081 Td (expect )Tj 0.0351 Tc 3.115 0 Td (that )Tj 0.0265 Tc 2.118 0 Td (the )Tj -0.0175 Tc 1.732 0 Td (effect )Tj 0.05 Tc 11.1292 0 0 10.2 153.49 316.09 Tm (of )Tj -0.035 Tc 10.1707 0 0 10.2 166.93 316.09 Tm (flow )Tj 9.3682 0 0 10.2 190 316.09 Tm (is )Tj 0.192 g -0.0006 Tc 10.2 0 0 10.2 201.11 316.09 Tm (relatively )Tj 0.263 g 0.0025 Tc 4.223 0 Td (small. )Tj 0.192 g 0.05 Tc 10.5034 0 0 10.2 274.01 316.09 Tm (In )Tj 0.263 g 0.0037 Tc 10.2 0 0 10.2 55.59 305.05 Tm (general, )Tj 0.192 g 0.0154 Tc 3.537 0 Td (however)Tj 0.349 g 0 Tc 3.515 0 Td (, )Tj 0.263 g 0.0061 Tc 0.296 0 Td (this )Tj 0.192 g -0.035 Tc 10.1489 0 0 10.2 148.24 305.05 Tm (is )Tj 0.263 g 0.0455 Tc 10.2 0 0 10.2 157.91 305.05 Tm (not )Tj 0.0087 Tc 1.693 0 Td (true. )Tj 0.192 g 0.0111 Tc 2.163 0 Td (With )Tj 0.263 g 0.0172 Tc 2.356 0 Td (higher )Tj 0.0098 Tc 2.909 0 Td (average )Tj -0.0306 Tc -19.154 -1.083 Td (flows )Tj 0.05 Tc 10.3922 0 0 10.2 84.36 294 Tm (\(or )Tj 0.0156 Tc 10.2 0 0 10.2 104.62 294 Tm (ventilation\), )Tj 0.0029 Tc 5.835 0 Td (the )Tj -0.0081 Tc 1.921 0 Td (effect )Tj 0.05 Tc 11.6856 0 0 10.2 213.49 294 Tm (of )Tj 0.192 g -0.035 Tc 10.1707 0 0 10.2 229.81 294 Tm (flow )Tj 0.263 g 0.009 Tc 10.2 0 0 10.2 254.8 294 Tm (is )Tj 0.0455 Tc 1.419 0 Td (not )Tj 0.192 g -0.0094 Tc -20.941 -1.035 Td (negligible )Tj 0.263 g 0.037 Tc 4.274 0 Td (and )Tj 0.0126 Tc 1.937 0 Td (must )Tj 0.0078 Tc 2.356 0 Td (be )Tj 0.0363 Tc 1.315 0 Td (taken )Tj 0.0364 Tc 2.629 0 Td (into )Tj 0.0264 Tc 1.975 0 Td (account. )Tj 0.0434 Tc -13.545 -1.081 Td (Another )Tj 0.0292 Tc 3.803 0 Td (factor )Tj 0.05 Tc 10.215 0 0 10.2 132.46 272.41 Tm (that )Tj 0.0128 Tc 10.2 0 0 10.2 152.62 272.41 Tm (may )Tj 0.0158 Tc 2.072 0 Td (have )Tj 0.192 g 0.0064 Tc 2.259 0 Td (reduced )Tj 0.263 g 0.0265 Tc 3.575 0 Td (the )Tj -0.0081 Tc 1.544 0 Td (effect )Tj 0.05 Tc 11.1292 0 0 10.2 274.45 272.41 Tm (of )Tj -0.035 Tc 10.1707 0 0 10.2 55.57 261.37 Tm (flow )Tj 10.1489 0 0 10.2 75.76 261.37 Tm (is )Tj 0.05 Tc 10.2 0 0 10.2 84.46 261.37 Tm (the )Tj -0.0006 Tc 1.554 0 Td (relatively )Tj 0.036 Tc 4.034 0 Td (short )Tj 0.0432 Tc 2.357 0 Td (duration )Tj 0.05 Tc 11.1292 0 0 10.2 204.85 261.37 Tm (of )Tj 0.0296 Tc 10.2 0 0 10.2 216.01 261.37 Tm (breathing )Tj 0.05 Tc 11.1292 0 0 10.2 259.09 261.37 Tm (of )Tj 0.0265 Tc 10.2 0 0 10.2 270.22 261.37 Tm (the )Tj 0.0251 Tc -21.082 -1.082 Td (test )Tj 0.0002 Tc 1.781 0 Td (gas )Tj -0.0079 Tc 1.648 0 Td (in )Tj 0.05 Tc 10.5338 0 0 10.2 101.66 250.33 Tm (our )Tj 0.192 g 0.0242 Tc 10.2 0 0 10.2 120.02 250.33 Tm (protocol. )Tj 0.263 g -0.0228 Tc 4.137 0 Td (As )Tj 0.192 g 0.0287 Tc 1.46 0 Td (reported )Tj 0.263 g -0.0022 Tc 3.861 0 Td (by )Tj 0.192 g 0 Tc 1.308 0 Td (T )Tj ET BT /Suspect <>BDC 0.263 g /T1_0 1 Tf -0.035 Tc 8.1141 0 0 10.2 236.63 250.33 Tm (ABKA )Tj EMC ET BT /T1_2 1 Tf 0.0207 Tc 9.9 0 0 9.9 261.99 250.33 Tm (et )Tj -0.0242 Tc 1.118 0 Td (a/. )Tj 0.349 g /T1_0 1 Tf 0 Tc 10.2 0 0 10.2 55.43 239.29 Tm ([)Tj 0.192 g -0.035 Tc 9.555 0 0 10.2 59.19 239.29 Tm (13], )Tj 0.263 g 0.0286 Tc 10.2 0 0 10.2 75.75 239.29 Tm (gradual )Tj 0.0239 Tc 3.387 0 Td (changes )Tj 0.0112 Tc 3.631 0 Td (take )Tj 0.0052 Tc 1.98 0 Td (place )Tj 0.0109 Tc 2.388 0 Td (over )Tj 0.0148 Tc 2.078 0 Td (minutes )Tj -0.0042 Tc 3.52 0 Td (\(a )Tj 0.0144 Tc 1.045 0 Td (much )Tj 0.192 g 0.0195 Tc -20.054 -1.082 Td (longer )Tj 0.0365 Tc 2.964 0 Td (duration )Tj 0.263 g 0.0392 Tc 4.008 0 Td (than )Tj 0.0082 Tc 2.204 0 Td (allowed )Tj 0.0391 Tc 3.578 0 Td (in )Tj 0.0496 Tc 1.175 0 Td (our )Tj 0.0011 Tc 1.784 0 Td (studies\). )Tj 0.0005 Tc 3.83 0 Td (Never\255)Tj -0.0001 Tc -19.536 -1.035 Td (theless, )Tj 0.0078 Tc 3.294 0 Td (they )Tj 0.0237 Tc 2.062 0 Td (found )Tj 0.0386 Tc 2.833 0 Td (no )Tj 0.0092 Tc 1.305 0 Td (significant )Tj -0.0175 Tc 4.568 0 Td (effect )Tj 0.05 Tc 10.5727 0 0 10.2 224.06 217.69 Tm (of )Tj 10.2654 0 0 10.2 235.58 217.69 Tm (an )Tj 0.0123 Tc 10.2 0 0 10.2 249.04 217.69 Tm (increase )Tj 0.05 Tc 11.1292 0 0 10.2 55.09 206.65 Tm (of )Tj 0.0158 Tc 10.2 0 0 10.2 67.18 206.65 Tm (ventilation )Tj 0.05 Tc 10.2564 0 0 10.2 116.06 206.65 Tm (on )Tj 0.0265 Tc 10.2 0 0 10.2 131.02 206.65 Tm (the )Tj 0.0348 Tc 1.601 0 Td (rate )Tj 0.05 Tc 11.1292 0 0 10.2 166.93 206.65 Tm (of )Tj 0.0231 Tc 10.2 0 0 10.2 179.51 206.65 Tm (water )Tj 0.192 g -0.035 Tc 10.0013 0 0 10.2 206.34 206.65 Tm (Jos)Tj 0.349 g -0.002 Tc 10.2 0 0 10.2 218.26 206.65 Tm (s. )Tj 0.263 g /T1_2 1 Tf 0.0183 Tc 9.9 0 0 9.9 54.82 178.33 Tm (Inspired )Tj 0.0032 Tc 3.717 0 Td (air )Tj 0.0219 Tc 1.5 0 Td (effects )Tj 0.192 g /T1_0 1 Tf 0.0226 Tc 10.2 0 0 10.2 64.76 161.05 Tm (When )Tj 0.263 g 0.0304 Tc 3.006 0 Td (ambient )Tj 0.0437 Tc 3.906 0 Td (air )Tj -0.035 Tc 9.3682 0 0 10.2 152.56 161.05 Tm (is )Tj 0.192 g 0.0224 Tc 10.2 0 0 10.2 164.17 161.05 Tm (breathed, )Tj 0.263 g 0.0029 Tc 4.468 0 Td (the )Tj 0.0148 Tc 1.779 0 Td (extent )Tj 0.05 Tc 11.1292 0 0 10.2 259.09 161.05 Tm (of )Tj 0.0072 Tc 10.2 0 0 10.2 273.04 161.05 Tm (its )Tj 0.0218 Tc -21.414 -1.082 Td (conditioning )Tj 0.05 Tc 10.2564 0 0 10.2 112.22 150.01 Tm (on )Tj 0.0303 Tc 10.2 0 0 10.2 127.1 150.01 Tm (arrival )Tj 0.044 Tc 3.153 0 Td (at )Tj 0.0029 Tc 1.231 0 Td (the )Tj 0.0202 Tc 1.651 0 Td (pharynx )Tj -0.035 Tc 10.1489 0 0 10.2 227.44 150.01 Tm (is )Tj 0.0153 Tc 10.2 0 0 10.2 237.97 150.01 Tm (evident )Tj -0.0022 Tc 3.4 0 Td (by )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 10.2 0 0 10.2 289.276 150.01 Tm (\225 )Tj EMC ET BT /T1_0 1 Tf 0.0029 Tc 10.2 0 0 10.2 55.1758 138.9736 Tm (the )Tj 0.016 Tc 1.827 0 Td (changes )Tj 0.192 g -0.0079 Tc 4.002 0 Td (in )Tj 0 Tc 1.411 0 Td (T )Tj 0.263 g 0.05 Tc 10.3398 0 0 10.2 141.97 138.97 Tm (and )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 8.2169 0 0 8 164.93 138.97 Tm (PH)Tj 0 Tc 6.2 0 0 6.2 177.55 137.05 Tm (2)Tj 8 0 0 8 181.35 138.97 Tm (0 )Tj EMC ET BT /T1_0 1 Tf 0.0038 Tc 10.2 0 0 10.2 193.93 138.97 Tm (between )Tj 0.192 g 0.0265 Tc 3.997 0 Td (the )Tj 0.263 g 0.0139 Tc 1.922 0 Td (airway )Tj 0.0236 Tc -19.576 -1.035 Td (opening )Tj 0.192 g 0.05 Tc 10.3398 0 0 10.2 93.01 128.41 Tm (and )Tj 0.0029 Tc 10.2 0 0 10.2 114.22 128.41 Tm (the )Tj 0.0219 Tc 1.698 0 Td (pharynx. )Tj 0.263 g 0.0079 Tc 4.177 0 Td (These )Tj 0.0082 Tc 2.87 0 Td (changes )Tj 0.192 g 0.05 Tc 10.2757 0 0 10.2 241.34 128.41 Tm (are )Tj 0.263 g 0.0301 Tc 10.2 0 0 10.2 259.18 128.41 Tm (much )Tj 0.192 g 0.0172 Tc -20.054 -1.083 Td (larger )Tj 0.0192 Tc 2.916 0 Td (for )Tj 0.0172 Tc 1.751 0 Td (nasal )Tj 0.0296 Tc 2.684 0 Td (breathing )Tj 0.263 g 0.0235 Tc 4.515 0 Td (than )Tj 0.192 g 0.0192 Tc 2.344 0 Td (for )Tj 0.263 g 0.0225 Tc 1.742 0 Td (oral )Tj 0.192 g 0.0355 Tc 2.128 0 Td (breathing)Tj 0.349 g 0 Tc 4.073 0 Td (. )Tj 0.263 g -0.0036 Tc -22.146 -1.082 Td (Also, )Tj 0.0265 Tc 2.447 0 Td (the )Tj -0.0004 Tc 1.498 0 Td (differences )Tj 0.192 g 0.0038 Tc 4.717 0 Td (between )Tj 0.263 g 0.013 Tc 3.615 0 Td (inspired )Tj 0.037 Tc 3.575 0 Td (and )Tj 0.0059 Tc 1.834 0 Td (expired )Tj 0.0002 Tc 3.343 0 Td (gas )Tj 0.0269 Tc -21.028 -1.082 Td (temperature )Tj 0.037 Tc 5.498 0 Td (and )Tj 0.192 g 0 Tc 2.075 0 Td (H)Tj /T1_1 1 Tf 6.2 0 0 6.2 140.11 93.36 Tm (2)Tj /T1_0 1 Tf 10.2 0 0 10.2 143.89 95.28 Tm (0 )Tj 0.0236 Tc 1.283 0 Td (partial )Tj 0.0231 Tc 3.153 0 Td (pressure )Tj 0.0252 Tc 3.902 0 Td (measured )Tj 0.05 Tc 10.7518 0 0 10.2 274.45 95.28 Tm (at )Tj 0.263 g 0.0265 Tc 10.2 0 0 10.2 54.7 84.72 Tm (the )Tj 0.192 g 0.028 Tc 1.839 0 Td (pharynx )Tj 0.05 Tc 10.2757 0 0 10.2 113.66 84.72 Tm (are )Tj 0.263 g 0.0163 Tc 10.2 0 0 10.2 132.82 84.72 Tm (smaller )Tj 0.192 g 0.0192 Tc 3.579 0 Td (for )Tj 0.263 g 0.0172 Tc 1.798 0 Td (nasal )Tj 0.192 g 0.0194 Tc 2.684 0 Td (breathing. )Tj 0.263 g 0.0252 Tc 4.79 0 Td (This )Tj -0.0089 Tc -20.517 -1.082 Td (implies )Tj 0.05 Tc 10.215 0 0 10.2 87.34 73.68 Tm (that )Tj 0.0265 Tc 10.2 0 0 10.2 107.02 73.68 Tm (the )Tj 0.0348 Tc 1.554 0 Td (water )Tj 0.05 Tc 10.3398 0 0 10.2 149.17 73.68 Tm (and )Tj 0.0274 Tc 10.2 0 0 10.2 167.99 73.68 Tm (heat )Tj 0.349 g 0.0152 Tc 2.014 0 Td (exchange )Tj 0.192 g 0.0177 Tc 4.143 0 Td (loads )Tj 0.05 Tc 10.7226 0 0 10.2 255.74 73.68 Tm (on )Tj 0.263 g 0.0265 Tc 10.2 0 0 10.2 269.74 73.68 Tm (the )Tj -0.0083 Tc 3.852 64.236 Td (lungs )Tj 0.0313 Tc 2.87 0 Td (are )Tj 0.192 g -0.035 Tc 10.1035 0 0 10.2 358.47 728.89 Tm (less )Tj 0.263 g -0.0044 Tc 10.2 0 0 10.2 380.05 728.89 Tm (for )Tj 0.0172 Tc 1.892 0 Td (nasal )Tj 0.0261 Tc 2.815 0 Td (as )Tj 0.0385 Tc 1.553 0 Td (compared )Tj 0.0212 Tc 4.95 0 Td (with )Tj 0.0225 Tc 2.532 0 Td (oral )Tj 0.0142 Tc -20.695 -1.082 Td (breathing. )Tj 0.192 g 0.05 Tc 10.4358 0 0 10.2 319.15 706.8 Tm (For )Tj 0.263 g -0.0224 Tc 10.2 0 0 10.2 336.86 706.8 Tm (all )Tj 0.005 Tc 1.22 0 Td (subjects, )Tj 0.05 Tc 10.5338 0 0 10.2 387.74 706.8 Tm (our )Tj 0.192 g 10.377 0 0 10.2 404.54 706.8 Tm (data )Tj 0.263 g 0.0282 Tc 10.2 0 0 10.2 425.68 706.8 Tm (indicate )Tj 0.05 Tc 10.5068 0 0 10.2 462.21 706.8 Tm (that )Tj 0.0056 Tc 10.2 0 0 10.2 481.91 706.8 Tm (with )Tj 0 Tc 2.062 0 Td (a )Tj 0.0078 Tc 0.762 0 Td (higher )Tj 0.192 g 0.0147 Tc -19.819 -1.035 Td (inhaled )Tj 0.263 g 0.0437 Tc 3.339 0 Td (air )Tj 0.0188 Tc 1.467 0 Td (temperature, )Tj 0.0265 Tc 5.6 0 Td (the )Tj 0.019 Tc 1.544 0 Td (exhaled )Tj 0.0316 Tc 3.585 0 Td (temperature )Tj -0.035 Tc 9.9755 0 0 10.2 522.23 696.24 Tm (will )Tj 0.0078 Tc 10.2 0 0 10.2 308.65 685.21 Tm [(be )-51(higher )]TJ 0.0261 Tc 4.13 0 Td (as )Tj 0.192 g 0.022 Tc 1.185 0 Td (reported )Tj 0.263 g -0.035 Tc 10.0482 0 0 10.2 402.25 685.21 Tm (by )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 8.5992 0 0 10.2 415.18 685.21 Tm (ANDERSON )Tj EMC ET BT 0.349 g /T1_2 1 Tf 0.05 Tc 10.6747 0 0 9.9 463.58 685.21 Tm (eta/. )Tj 0.263 g /T1_0 1 Tf -0.035 Tc 9.8344 0 0 10.2 488.04 685.21 Tm (\(14]. )Tj 0.0409 Tc 10.2 0 0 10.2 508.71 685.21 Tm (This )Tj 0.192 g -0.035 Tc 10.1489 0 0 10.2 530.8 685.21 Tm (is )Tj 0.263 g 0.0157 Tc 10.2 0 0 10.2 308.06 674.17 Tm (caused )Tj -0.0022 Tc 3.117 0 Td (by )Tj 0.0029 Tc 1.362 0 Td (the )Tj 0.0205 Tc 1.507 0 Td (warming )Tj 0.05 Tc 11.1292 0 0 10.2 409.33 674.17 Tm (of )Tj 0.0265 Tc 10.2 0 0 10.2 420.94 674.17 Tm (the )Tj 0.0185 Tc 1.6 0 Td (mucosal )Tj 0.0177 Tc 3.753 0 Td (surface )Tj 0.192 g 0.0351 Tc 3.251 0 Td (during )Tj 0.263 g 0.0196 Tc -19.622 -1.035 Td (inhalation. )Tj 0.192 g -0.0007 Tc 4.897 0 Td (Relatively )Tj 0.263 g 0.0204 Tc 4.419 0 Td (dry )Tj 0.0147 Tc 1.743 0 Td (inhaled )Tj 0.05 Tc 10.5084 0 0 10.2 455.89 663.61 Tm (air )Tj 0.0202 Tc 10.2 0 0 10.2 471.27 663.61 Tm (leads )Tj 0.05 Tc 10.4772 0 0 10.2 496.29 663.61 Tm (to )Tj 0.0154 Tc 10.2 0 0 10.2 508.21 663.61 Tm (evapo\255)Tj 0.0329 Tc -19.567 -1.083 Td (ration )Tj 0.05 Tc 10.3398 0 0 10.2 339.73 652.56 Tm (and )Tj 0.0136 Tc 10.2 0 0 10.2 361.34 652.56 Tm (cooling )Tj 0.05 Tc 11.1292 0 0 10.2 398.29 652.56 Tm (of )Tj 0.0265 Tc 10.2 0 0 10.2 412.78 652.56 Tm (the )Tj 0.0185 Tc 1.835 0 Td (mucosal )Tj 0.0198 Tc 4.035 0 Td (surface, )Tj -0.0094 Tc 3.872 0 Td (which )Tj 0.0235 Tc -20.009 -1.081 Td (counters )Tj 0.0029 Tc 4.008 0 Td (the )Tj 0.001 Tc 1.682 0 Td (sensible )Tj 0.0274 Tc 3.636 0 Td (heat )Tj 0.0283 Tc 2.164 0 Td (transfer )Tj 0.0204 Tc 3.709 0 Td (from )Tj 0.05 Tc 2.456 0 Td (the )Tj 0.192 g 0.0147 Tc 1.735 0 Td (inhaled )Tj 0.263 g 0.0002 Tc -19.342 -1.035 Td (gas )Tj 0.0253 Tc 1.748 0 Td (to )Tj 0.0265 Tc 1.224 0 Td (the )Tj 0.349 g 0.0063 Tc 1.635 0 Td (surface. )Tj 0.263 g 0.0261 Tc 3.635 0 Td (Although )Tj 0.0265 Tc 4.424 0 Td (the )Tj 0.0316 Tc 1.694 0 Td (temperature )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 10.9991 0 0 10.2 511.1 630.97 Tm (qf )Tj EMC ET BT 0.192 g /T1_0 1 Tf 0.0265 Tc 10.2 0 0 10.2 524.14 630.97 Tm (the )Tj -0.0079 Tc -21.135 -1.083 Td (in)Tj 0.349 g -0.0057 Tc 0.794 0 Td (spi)Tj 0.192 g -0.0026 Tc 1.189 0 Td (red )Tj 0.263 g 0.05 Tc 10.8368 0 0 10.2 347.5 619.92 Tm (hot )Tj 0.0437 Tc 10.2 0 0 10.2 367.1 619.92 Tm (air )Tj 0.0017 Tc 1.656 0 Td (was )Tj 0.023 Tc 2.117 0 Td (more )Tj 0.0392 Tc 2.682 0 Td (than )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.01 Tc 10.2 0 0 10.2 458.0534 619.92 Tm (10\260C )Tj EMC ET BT /T1_0 1 Tf 0.018 Tc 10.2 0 0 10.2 484.706 619.92 Tm (above )Tj 0.0267 Tc 3.023 0 Td (body )Tj 0.0231 Tc -20.285 -1.081 Td (temperature, )Tj 0.0265 Tc 6.071 0 Td (the )Tj 0.0269 Tc 2.071 0 Td (temperature )Tj 0.05 Tc 11.6856 0 0 10.2 451.09 608.89 Tm (of )Tj 0.0265 Tc 10.2 0 0 10.2 468.46 608.89 Tm (the )Tj 0.0218 Tc 2.059 0 Td (subsequent )Tj 0.0059 Tc -17.785 -1.035 Td (expired )Tj 0.0437 Tc 3.389 0 Td (air )Tj 0.0017 Tc 1.468 0 Td (was )Tj 0.0305 Tc 1.921 0 Td (around )Tj 0.192 g 0.011 Tc 3.399 0 Td (body )Tj 0.263 g 0.0231 Tc 2.444 0 Td (temperature. )Tj -0.0228 Tc -11.624 -1.082 Td (As )Tj 0.012 Tc 1.497 0 Td (found )Tj -0.0022 Tc 2.835 0 Td (by )Tj 0.033 Tc 1.354 0 Td (other )Tj 0.0191 Tc 2.543 0 Td (investigators )Tj -0.0297 Tc 5.677 0 Td ([5, )Tj 0.192 g -0.035 Tc 9.3096 0 0 10.2 474.62 587.29 Tm (7])Tj 0.349 g 0 Tc 10.2 0 0 10.2 482.72 587.29 Tm (, )Tj 0.263 g 0.0029 Tc 0.625 0 Td (the )Tj 0.0059 Tc 1.591 0 Td (expired )Tj 0.0237 Tc -19.339 -1.083 Td (gas )Tj 0.0017 Tc 1.702 0 Td (was )Tj 0.0455 Tc 1.882 0 Td (not )Tj 0.0349 Tc 1.728 0 Td (saturated )Tj 0.192 g 0.0187 Tc 4.19 0 Td (\(based )Tj 0.263 g 0.05 Tc 10.2564 0 0 10.2 436.22 576.24 Tm (on )Tj 0.0265 Tc 10.2 0 0 10.2 451.18 576.24 Tm (the )Tj 0.0483 Tc 1.6 0 Td (vapour )Tj 0.0163 Tc 3.345 0 Td (pressure )Tj 0.05 Tc 11.1292 0 0 10.2 308.05 565.68 Tm (of )Tj 0.0385 Tc 10.2 0 0 10.2 320.66 565.68 Tm (pure )Tj 0.0177 Tc 2.256 0 Td (water\) )Tj 0.0279 Tc 3.003 0 Td (after )Tj 0.0214 Tc 2.355 0 Td (inspiration )Tj 0.05 Tc 11.6856 0 0 10.2 447.73 565.68 Tm (of )Tj 0.0388 Tc 10.2 0 0 10.2 460.21 565.68 Tm (either )Tj 0.0304 Tc 2.825 0 Td (ambient )Tj 0.05 Tc 10.5727 0 0 10.2 527.42 565.68 Tm (or )Tj 0.0458 Tc 10.2 0 0 10.2 308.63 554.65 Tm (hot )Tj 0.0086 Tc 1.874 0 Td (air. )Tj 0.0252 Tc 1.836 0 Td (This )Tj 0.0229 Tc 2.352 0 Td (can )Tj 0.0078 Tc 2.034 0 Td (be )Tj 0.192 g 0.0156 Tc 1.457 0 Td (relat)Tj 0.349 g 0.0179 Tc 1.825 0 Td (ed )Tj 0.263 g 0.0253 Tc 1.562 0 Td (to )Tj 0.0265 Tc 1.365 0 Td (the )Tj 0.0215 Tc 1.78 0 Td (cooling )Tj 0.05 Tc 11.1292 0 0 10.2 509.65 554.65 Tm (of )Tj 0.0029 Tc 10.2 0 0 10.2 524.14 554.65 Tm (the )Tj 0.0106 Tc -21.176 -1.082 Td (mucosal )Tj -0.0225 Tc 3.954 0 Td (wall )Tj 0.0449 Tc 2.167 0 Td (by )Tj 0.0339 Tc 1.494 0 Td (evaporation )Tj 0.0351 Tc 5.554 0 Td (during )Tj 0.192 g 0.0214 Tc 3.296 0 Td (inspiration )Tj 0.263 g 0.0304 Tc 5.029 0 Td (so )Tj 0.349 g 0.0351 Tc -21.447 -1.083 Td (that )Tj 0.263 g 0.0029 Tc 1.882 0 Td (the )Tj 0.0269 Tc 1.506 0 Td (temperature )Tj 0.05 Tc 10.7518 0 0 10.2 396.85 532.56 Tm (at )Tj 10.2 0 0 10.2 407.5 532.56 Tm (the )Tj -0.0068 Tc 1.507 0 Td (wall )Tj 0.0252 Tc 1.976 0 Td (was )Tj -0.008 Tc 1.827 0 Td (less )Tj 0.05 Tc 10.2803 0 0 10.2 479.01 532.56 Tm (than )Tj 0.0265 Tc 10.2 0 0 10.2 501.1 532.56 Tm (the )Tj 0.0012 Tc 1.546 0 Td (local )Tj 0.0002 Tc -20.471 -1.035 Td (gas )Tj 0.0188 Tc 1.748 0 Td (temperature. )Tj 0.192 g 0.0166 Tc 5.64 0 Td (Theoretically)Tj 0.349 g 0 Tc 5.546 0 Td (, )Tj 0.263 g 0.618 0 Td (a )Tj 0.192 g 0.0145 Tc 0.894 0 Td (decrease )Tj 0.263 g 0.05 Tc 10.5727 0 0 10.2 495.74 522 Tm (of )Tj 0.0034 Tc 10.2 0 0 10.2 508.26 522 Tm (2\260C )Tj 0.05 Tc 11.1292 0 0 10.2 527.89 522 Tm (of )Tj 0.0029 Tc 10.2 0 0 10.2 308.62 510.97 Tm (the )Tj 0.0106 Tc 1.6 0 Td (mucosal )Tj 0.192 g 0.0074 Tc 3.805 0 Td (lining )Tj 0.0014 Tc 2.69 0 Td (reduces )Tj 0.263 g 0.0265 Tc 3.481 0 Td (the )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 10.2 0 0 10.2 442.9846 510.97 Tm (H)Tj 6.3001 0 0 6.3001 452.12 508.56 Tm (2)Tj 10.2 0 0 10.2 455.89 510.97 Tm (0 )Tj EMC ET BT /T1_0 1 Tf 0.0388 Tc 10.2 0 0 10.2 467.4976 510.97 Tm (vapour )Tj 0.192 g 0.0163 Tc 3.345 0 Td (pressure )Tj 0.263 g 0.05 Tc 10.7518 0 0 10.2 308.05 499.93 Tm (at )Tj 0.0029 Tc 10.2 0 0 10.2 320.14 499.93 Tm (the )Tj 0.0139 Tc 1.592 0 Td (airway )Tj -0.0225 Tc 3.162 0 Td (wall )Tj 0.192 g -0.0022 Tc 2.025 0 Td (by )Tj 0.263 g 0.0155 Tc 1.354 0 Td (almost )Tj ET BT /Suspect <>BDC 0.067 g /T1_1 1 Tf 0 Tc 9.2 0 0 9.2 436.07 499.93 Tm (I )Tj EMC /Suspect <>BDC 0.192 g 0.05 Tc 9.4826 0 0 9.2 440.05 499.93 Tm (0% )Tj EMC ET BT 0.263 g /T1_0 1 Tf -0.035 Tc 9.4074 0 0 10.2 458.65 499.93 Tm ([3]. )Tj /T1_2 1 Tf 0.0013 Tc 9.9 0 0 9.9 308.44 472.56 Tm (Comparison )Tj 0.05 Tc 12.4923 0 0 9.9 361.34 472.56 Tm (of )Tj 0.0269 Tc 9.9 0 0 9.9 372.91 472.56 Tm (normal )Tj 0.05 Tc 9.9549 0 0 9.9 405.54 472.56 Tm (and )Tj ET BT /Suspect <>BDC /T1_2 1 Tf 10.2074 0 0 9.9 424.6 472.56 Tm (CF )Tj EMC ET BT /T1_2 1 Tf 0.0189 Tc 9.9 0 0 9.9 440.67 472.56 Tm (subjects )Tj /T1_0 1 Tf 0.0261 Tc 10.2 0 0 10.2 317.74 456.25 Tm (Although )Tj 0.0265 Tc 4.282 0 Td (the )Tj ET BT /Suspect <>BDC 0.192 g /T1_0 1 Tf 0 Tc 10.2 0 0 10.2 376.747 456.25 Tm (H)Tj 6.9001 0 0 6.9001 385.4 453.84 Tm (2)Tj 10.2 0 0 10.2 389.17 456.25 Tm (0 )Tj EMC ET BT 0.263 g /T1_0 1 Tf 0.0314 Tc 10.2 0 0 10.2 399.3802 456.25 Tm (partial )Tj 0.0231 Tc 3.012 0 Td (pressure )Tj 0.05 Tc 11.1292 0 0 10.2 468.37 456.25 Tm (of )Tj 0.0138 Tc 10.2 0 0 10.2 479.41 456.25 Tm (expired )Tj 0.0237 Tc 3.343 0 Td (gas )Tj 0.192 g 0 Tc 1.648 0 Td (i)Tj 0.349 g 0.229 0 Td (s )Tj 0.263 g 0.0478 Tc -22.02 -1.082 Td (about )Tj 0.0265 Tc 2.784 0 Td (the )Tj 0.0146 Tc 1.635 0 Td (same )Tj 0.0427 Tc 2.45 0 Td (for )Tj 0.05 Tc 10.7486 0 0 10.2 394.93 445.21 Tm (CF )Tj 0.037 Tc 10.2 0 0 10.2 411.74 445.21 Tm (and )Tj 0.192 g 1.985 0 Td (normal )Tj 0.263 g 0.0248 Tc 3.38 0 Td (groups, )Tj 0.0061 Tc 3.583 0 Td (this )Tj 0.0229 Tc 1.827 0 Td (can )Tj 0.0102 Tc -20.933 -1.035 Td (mistakenly )Tj -0.0002 Tc 4.746 0 Td (lead )Tj 0.05 Tc 10.4772 0 0 10.2 376.29 434.65 Tm (to )Tj 0.0265 Tc 10.2 0 0 10.2 387.82 434.65 Tm (the )Tj 0.0127 Tc 1.498 0 Td (conclusion )Tj 0.05 Tc 10.215 0 0 10.2 451.66 434.65 Tm (that )Tj 0.192 g 0.0386 Tc 10.2 0 0 10.2 471.35 434.65 Tm (no )Tj 0.0009 Tc 1.309 0 Td (difference )Tj -0.0079 Tc 4.284 0 Td (in )Tj 0.263 g 0.0149 Tc -21.64 -1.082 Td (humidification )Tj -0.0019 Tc 6.908 0 Td (exists. )Tj 0.192 g 0.0252 Tc 3.39 0 Td (This )Tj 0.263 g 0.0194 Tc 2.681 0 Td (conclusion, )Tj 0.0111 Tc 5.656 0 Td (however, )Tj 0.0065 Tc -18.595 -1.083 Td (ignores )Tj 0.0265 Tc 3.488 0 Td (the )Tj 0.0283 Tc 1.779 0 Td (fact )Tj 0.05 Tc 10.215 0 0 10.2 383.02 412.56 Tm (that )Tj 0.0265 Tc 10.2 0 0 10.2 405.1 412.56 Tm (the )Tj 0.0445 Tc 1.788 0 Td (transport )Tj 0.0107 Tc 4.427 0 Td (processes )Tj 0.0125 Tc 4.421 0 Td (reach )Tj 0.0228 Tc -20.198 -1.081 Td (equilibr)Tj 0.067 g 0 Tc 3.25 0 Td (i)Tj 0.192 g 0.0412 Tc 0.29 0 Td (um )Tj 0.263 g -0.0032 Tc 2.109 0 Td (locally )Tj 0.0257 Tc 3.481 0 Td (during )Tj 0.0228 Tc 3.528 0 Td (expiration )Tj 0.0024 Tc 5.092 0 Td (which )Tj 0.0464 Tc 3.191 0 Td (can )Tj 0.0127 Tc -20.941 -1.035 Td (camouflage )Tj 0.192 g 0.0113 Tc 5.185 0 Td (humidification )Tj 0.263 g -0.0004 Tc 6.485 0 Td (differences )Tj 0.05 Tc 10.215 0 0 10.2 476.14 390.97 Tm (that )Tj 0.0268 Tc 10.2 0 0 10.2 497.66 390.97 Tm (occur )Tj 0.192 g 0.05 Tc 10.2564 0 0 10.2 525.5 390.97 Tm (on )Tj 0.263 g 0.0138 Tc 10.2 0 0 10.2 308.08 379.93 Tm (inspiration. )Tj 0.192 g 0.0393 Tc 5.274 0 Td (During )Tj 0.0261 Tc 3.526 0 Td (inspiration )Tj 0.263 g 0.05 Tc 11.1292 0 0 10.2 449.17 379.93 Tm (of )Tj 0.0304 Tc 10.2 0 0 10.2 463.58 379.93 Tm (ambient )Tj 0.0243 Tc 3.906 0 Td (air, )Tj 0.0029 Tc 1.984 0 Td (the )Tj 0.0182 Tc -21.128 -1.082 Td (normal )Tj 0.037 Tc 3.332 0 Td (and )Tj 0.05 Tc 11.1325 0 0 10.2 361.8 368.89 Tm (CF )Tj 0.0232 Tc 10.2 0 0 10.2 379.11 368.89 Tm (groups )Tj 0.0248 Tc 3.199 0 Td (did )Tj 0.192 g 0.0455 Tc 1.75 0 Td (not )Tj 0.263 g 0.0263 Tc 1.728 0 Td (show )Tj 0.037 Tc 2.545 0 Td (any )Tj 0.0045 Tc 1.925 0 Td (significant )Tj 0.192 g -0.0052 Tc -18.161 -1.083 Td (differences )Tj 0.263 g 0.0056 Tc 4.856 0 Td (with )Tj 0.192 g 0.0071 Tc 2.306 0 Td (respect )Tj 0.263 g 0.0253 Tc 3.293 0 Td (to )Tj 0.0002 Tc 1.311 0 Td (gas )Tj 0.0316 Tc 1.795 0 Td (temperature )Tj 0.05 Tc 10.5727 0 0 10.2 502.46 357.84 Tm (or )Tj 0.192 g 0 Tc 10.2 0 0 10.2 515.95 357.84 Tm (H)Tj /T1_1 1 Tf 6.2 0 0 6.2 524.59 355.44 Tm (2)Tj /T1_0 1 Tf 10.2 0 0 10.2 528.37 357.84 Tm (0 )Tj 0.263 g 0.0236 Tc -21.634 -1.035 Td (partial )Tj 0.0163 Tc 3.012 0 Td (pressure )Tj 0.05 Tc 10.7518 0 0 10.2 376.21 347.28 Tm (at )Tj 0.0029 Tc 10.2 0 0 10.2 387.34 347.28 Tm (the )Tj 0.028 Tc 1.557 0 Td (pharynx )Tj 0.05 Tc 11.1292 0 0 10.2 441.01 347.28 Tm (or )Tj 0.0233 Tc 10.2 0 0 10.2 453.02 347.28 Tm (airway )Tj 0.0181 Tc 3.106 0 Td (opening. )Tj 0.192 g -0.035 Tc 9.9514 0 0 10.2 525.08 347.28 Tm (By )Tj 0.263 g 0.0289 Tc 10.2 0 0 10.2 307.58 336.25 Tm (contrast, )Tj 0.05 Tc 10.2564 0 0 10.2 347.42 336.25 Tm (on )Tj 0.0261 Tc 10.2 0 0 10.2 360.88 336.25 Tm (inspiration )Tj 0.05 Tc 11.1292 0 0 10.2 409.81 336.25 Tm (of )Tj 0.192 g 0.0458 Tc 10.2 0 0 10.2 421.43 336.25 Tm (hot )Tj 0.263 g 0.0437 Tc 1.638 0 Td (air )Tj 0.0311 Tc 1.42 0 Td (through )Tj 0.0265 Tc 3.624 0 Td (the )Tj 0.192 g 0.0179 Tc 1.554 0 Td (nose )Tj 0.263 g 0.05 Tc 10.5727 0 0 10.2 526.94 336.25 Tm (or )Tj 0.033 Tc 10.2 0 0 10.2 307.66 325.21 Tm (mouth, )Tj -0.0103 Tc 3.662 0 Td (even )Tj 0.0286 Tc 2.597 0 Td (though )Tj 0.0029 Tc 3.671 0 Td (the )Tj 0.0002 Tc 1.923 0 Td (gas )Tj 0.0316 Tc 2.03 0 Td (temperature )Tj -0.0079 Tc 5.782 0 Td (in )Tj 0.0265 Tc 1.465 0 Td (the )Tj 0.0202 Tc -21.125 -1.083 Td (pharynx )Tj 0.0017 Tc 3.809 0 Td (was )Tj 0.0265 Tc 1.975 0 Td (the )Tj 0.0146 Tc 1.635 0 Td (same )Tj 0.0192 Tc 2.497 0 Td (for )Tj 0.05 Tc 10.264 0 0 10.2 425.29 314.16 Tm (both )Tj 0.0248 Tc 10.2 0 0 10.2 449.19 314.16 Tm (groups, )Tj ET BT /Suspect <>BDC 0.192 g /T1_0 1 Tf -0.035 Tc 9.7748 0 0 10.2 485.24 314.16 Tm (PH)Tj 0 Tc 6.3001 0 0 6.3001 497.72 311.76 Tm (2)Tj 10.2 0 0 10.2 501.02 314.16 Tm (o )Tj EMC ET BT 0.263 g /T1_0 1 Tf 0.05 Tc 11.3843 0 0 10.2 510.6 314.16 Tm (at )Tj 0.0265 Tc 10.2 0 0 10.2 523.18 314.16 Tm (the )Tj 0.028 Tc -21.125 -1.034 Td (pharynx )Tj 0.0017 Tc 4.044 0 Td (was )Tj 0.0115 Tc 2.157 0 Td (lower )Tj 0.0192 Tc 2.916 0 Td (for )Tj 0.0029 Tc 1.844 0 Td (the )Tj 0.05 Tc 11.1325 0 0 10.2 438.12 303.61 Tm (CF )Tj 0.0145 Tc 10.2 0 0 10.2 458.26 303.61 Tm (subjects )Tj 0.05 Tc 10.2803 0 0 10.2 498.21 303.61 Tm (than )Tj -0.0044 Tc 10.2 0 0 10.2 524.05 303.61 Tm (for )Tj 0.037 Tc -21.214 -1.083 Td (normal )Tj 0.005 Tc 3.705 0 Td (subjects. )Tj 0.192 g 0 Tc 4.294 0 Td (A)Tj 0.349 g 0.741 0 Td (s )Tj 0.263 g 1.086 0 Td (a )Tj 0.0114 Tc 1.224 0 Td (consequence, )Tj 0.0265 Tc 6.267 0 Td (the )Tj 0.0094 Tc 2.025 0 Td (relative )Tj 0.192 g 0.0162 Tc -19.341 -1.081 Td (humidity )Tj 0.263 g 0.05 Tc 11.1292 0 0 10.2 351.73 281.53 Tm (of )Tj 0.0265 Tc 10.2 0 0 10.2 366.22 281.53 Tm (the )Tj 0.05 Tc 10.7486 0 0 10.2 385.33 281.53 Tm (CF )Tj 0.0145 Tc 10.2 0 0 10.2 404.5 281.53 Tm (subjects )Tj -0.035 Tc 9.3682 0 0 10.2 444.4 281.53 Tm (is )Tj 0.0164 Tc 10.2 0 0 10.2 456.38 281.53 Tm (also )Tj 0.067 g 0 Tc 2.26 0 Td (l)Tj 0.263 g 0.0153 Tc 0.281 0 Td (ower )Tj 0.044 Tc 2.635 0 Td (at )Tj 0.0265 Tc 1.373 0 Td (the )Tj 0.0152 Tc -21.125 -1.082 Td (pharynx. )Tj 0.192 g 0.0252 Tc 0.93 -1.083 Td (This )Tj 0.263 g 0.0009 Tc 2.446 0 Td (difference )Tj 0.0391 Tc 4.614 0 Td (in )Tj 0.192 g 0 Tc 1.462 0 Td (H)Tj 0.349 g 6.9001 0 0 6.9001 412.28 257.53 Tm (2)Tj 10.2 0 0 10.2 416.05 259.44 Tm (0 )Tj 0.263 g 0.0379 Tc 1.374 0 Td (transport, )Tj 0.0141 Tc 4.754 0 Td (which )Tj -0.035 Tc 9.3682 0 0 10.2 510.64 259.44 Tm (is )Tj 0.0265 Tc 10.2 0 0 10.2 523.18 259.44 Tm (the )Tj 0.0304 Tc -21.129 -1.081 Td (major )Tj 0.192 g 0.0216 Tc 2.769 0 Td (distinction )Tj 0.263 g -0.0311 Tc 4.809 0 Td (we )Tj 0.192 g 0.0237 Tc 1.496 0 Td (found )Tj 0.0116 Tc 2.835 0 Td (between )Tj 0.263 g 0.0265 Tc 3.762 0 Td (the )Tj 0.0046 Tc 1.694 0 Td (two )Tj 0.0248 Tc 1.875 0 Td (groups, )Tj 0.0363 Tc -19.287 -1.035 Td (may )Tj -0.035 Tc 10.1515 0 0 10.2 329.29 237.85 Tm (be )Tj 0.0106 Tc 10.2 0 0 10.2 342.14 237.85 Tm (associated )Tj 0.192 g 0.0056 Tc 4.574 0 Td (with )Tj 0.263 g 0.0163 Tc 2.156 0 Td (drying )Tj 0.05 Tc 11.1292 0 0 10.2 441.49 237.85 Tm (of )Tj 0.192 g 0.0265 Tc 10.2 0 0 10.2 454.06 237.85 Tm (the )Tj 0.263 g 0.0185 Tc 1.6 0 Td (mucosal )Tj -0.0041 Tc 3.805 0 Td (lining. )Tj 0.192 g 0.0194 Tc -19.758 -1.083 Td (Although )Tj 0.263 g -0.0311 Tc 4.472 0 Td (we )Tj 0.0265 Tc 1.638 0 Td (could )Tj 0.0455 Tc 2.879 0 Td (not )Tj 0.192 g 0.016 Tc 1.874 0 Td (directly )Tj 0.263 g -0.0055 Tc 3.678 0 Td (verify )Tj 0.05 Tc 10.5068 0 0 10.2 485.73 226.8 Tm (that )Tj 0.0257 Tc 10.2 0 0 10.2 508.22 226.8 Tm (drying )Tj 0.192 g 0.05 Tc 10.364 0 0 10.2 307.1 215.76 Tm (oc)Tj 0.349 g 0.0301 Tc 10.2 0 0 10.2 316.7 215.76 Tm (curred )Tj 0.263 g 0.0014 Tc 3.068 0 Td (when )Tj 0.05 Tc 10.4873 0 0 10.2 373.43 215.76 Tm (hot )Tj 0.0437 Tc 10.2 0 0 10.2 390.62 215.76 Tm (air )Tj 0.0017 Tc 1.421 0 Td (was )Tj 0.192 g 0.0155 Tc 1.875 0 Td (inspired, )Tj 0.349 g -0.0079 Tc 3.906 0 Td (in)Tj 0.192 g 0.0178 Tc 0.798 0 Td (direct )Tj 0.263 g 0.0067 Tc 2.681 0 Td (evidence )Tj 0.0229 Tc -18.87 -1.081 Td (can )Tj 0.0078 Tc 1.94 0 Td (be )Tj 0.0291 Tc 1.354 0 Td (obtained )Tj 0.0048 Tc 4.14 0 Td (from )Tj 0.0029 Tc 2.503 0 Td (the )Tj -0.0225 Tc 1.695 0 Td (wall )Tj 0.0231 Tc 2.164 0 Td (temperature. )Tj -0.015 Tc 5.785 0 Td (By )Tj 0.0265 Tc 1.603 0 Td (the )Tj 0.0178 Tc -21.185 -1.036 Td (end )Tj 0.05 Tc 11.1292 0 0 10.2 325.81 194.16 Tm (of )Tj 0.192 g 0.0261 Tc 10.2 0 0 10.2 337.84 194.16 Tm (inspiration )Tj 0.263 g 0.0265 Tc 4.853 0 Td (the )Tj -0.0225 Tc 1.601 0 Td (wall )Tj 0.0269 Tc 2.07 0 Td (temperature )Tj 0.05 Tc 10.7518 0 0 10.2 479.41 194.16 Tm (at )Tj 10.2 0 0 10.2 490.54 194.16 Tm (the )Tj 0.0139 Tc 1.639 0 Td (airway )Tj 0.0184 Tc -19.624 -1.081 Td (openings )Tj 0.0017 Tc 4.009 0 Td (was )Tj 0.192 g 0.0172 Tc 1.835 0 Td (higher )Tj 0.263 g 0.0192 Tc 2.908 0 Td (for )Tj 0.05 Tc 11.1325 0 0 10.2 411.72 183.13 Tm (CF )Tj 0.0392 Tc 10.2 0 0 10.2 428.62 183.13 Tm (than )Tj 0.0427 Tc 2.109 0 Td (for )Tj 0.192 g 0.0276 Tc 1.563 0 Td (normal )Tj 0.263 g 0.005 Tc 3.281 0 Td (subjects. )Tj 0.0252 Tc -18.866 -1.082 Td (This )Tj 0.349 g 0.0182 Tc 2.07 0 Td (co)Tj 0.192 g -0.0029 Tc 0.998 0 Td (uld )Tj 0.263 g 0.0215 Tc 1.545 0 Td (indicate )Tj -0.0237 Tc 3.575 0 Td (less )Tj 0.0339 Tc 1.645 0 Td (evaporation )Tj 0.05 Tc 10.3398 0 0 10.2 461.17 172.09 Tm (and )Tj 0.0144 Tc 10.2 0 0 10.2 480.46 172.09 Tm (therefore )Tj -0.0237 Tc 3.993 0 Td (less )Tj 0.0177 Tc -20.993 -1.082 Td (surface )Tj 0.0215 Tc 3.204 0 Td (cooling )Tj 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4.81 0 Td (between )Tj 0.0456 Tc 4.216 0 Td (normal )Tj 0.05 Tc 10.0265 0 0 9.9 189.02 523.92 Tm (and )Tj 10.7486 0 0 9.9 212.53 523.92 Tm (CF )Tj 0.0218 Tc 9.9 0 0 9.9 233.14 523.92 Tm (subjects )Tj 0.0188 Tc -19.526 -1.067 Td (would )Tj -0.0122 Tc 2.96 0 Td (be )Tj 0.0082 Tc 1.2 0 Td (even )Tj 0.0415 Tc 2.185 0 Td (greater )Tj 0.0233 Tc 3.304 0 Td (when )Tj 0.0215 Tc 2.569 0 Td (the )Tj 0.0218 Tc 1.588 0 Td (subjects )Tj 0.212 0.212 0.208 rg 0.0292 Tc 3.642 0 Td (inhale )Tj 0.0487 Tc 2.916 0 Td (hotter )Tj 0.29 0.29 0.286 rg 0.05 Tc 10.0265 0 0 9.9 39.74 502.33 Tm (and )Tj 0.0398 Tc 9.9 0 0 9.9 58.95 502.33 Tm (drier )Tj 0.0219 Tc 2.423 0 Td (air. )Tj 0.114 g 0 Tc 1.796 0 Td (T)Tj 0.29 0.29 0.286 rg 0.0008 Tc 0.734 0 Td (his )Tj 0.0443 Tc 1.542 0 Td (can )Tj 0.0363 Tc 1.902 0 Td (be )Tj 0.028 Tc 1.355 0 Td (validated )Tj 0.0448 Tc 4.307 0 Td (only )Tj -0.0207 Tc 2.338 0 Td (by )Tj 0.0415 Tc 1.403 0 Td (making )Tj 0.0299 Tc -19.745 -1.116 Td (simultaneous )Tj 0.0419 Tc 6.121 0 Td (measu)Tj 0.114 g 0 Tc 2.716 0 Td (r)Tj 0.29 0.29 0.286 rg 0.0394 Tc 0.329 0 Td (ements )Tj 0.05 Tc 10.5727 0 0 9.9 165.5 491.28 Tm (of )Tj 0.0307 Tc 9.9 0 0 9.9 178.94 491.28 Tm (airway )Tj 0.0326 Tc 3.39 0 Td (surface )Tj 0.0211 Tc 3.552 0 Td (tem\255)Tj 0.0336 Tc -20.99 -1.067 Td (perature, )Tj 0.0201 Tc 4.208 0 Td (gas )Tj 0.0376 Tc 1.8 0 Td (temperature, )Tj 0.05 Tc 10.0265 0 0 9.9 157.34 480.72 Tm (and )Tj 0.0406 Tc 9.9 0 0 9.9 177.11 480.72 Tm (water )Tj 0.0471 Tc 2.811 0 Td (vapour )Tj 0.212 0.212 0.208 rg 0.0371 Tc 3.398 0 Td (partial )Tj 0.29 0.29 0.286 rg 0.0203 Tc -20.121 -1.114 Td (pressure. )Tj 0.212 0.212 0.208 rg 0.049 Tc 4.305 0 Td (Temperature )Tj 0.29 0.29 0.286 rg 0.0319 Tc 6.115 0 Td (measurements )Tj 0.212 0.212 0.208 rg 0.0317 Tc 6.634 0 Td (alone )Tj 0.29 0.29 0.286 rg 0.05 Tc 9.9087 0 0 9.9 236.54 469.69 Tm (are )Tj 0.212 0.212 0.208 rg 0.0107 Tc 9.9 0 0 9.9 255.28 469.69 Tm (in\255)Tj 0.29 0.29 0.286 rg 0.0093 Tc -21.824 -1.115 Td (sufficient )Tj 0.0496 Tc 4.23 0 Td (to )Tj 0.0295 Tc 1.158 0 Td (infer )Tj 0.0215 Tc 2.333 0 Td (the )Tj 0.0299 Tc 1.591 0 Td (extent )Tj 0.05 Tc 11.1292 0 0 9.9 160.69 458.65 Tm (of )Tj 0.0406 Tc 9.9 0 0 9.9 172.31 458.65 Tm (water )Tj 0.05 Tc 10.087 0 0 9.9 199.18 458.65 Tm (transport )Tj 0.0493 Tc 9.9 0 0 9.9 242.4 458.65 Tm (under )Tj 0.0442 Tc -20.523 -1.115 Td (such )Tj 0.0407 Tc 2.234 0 Td (conditions )Tj -0.0149 Tc 4.834 0 Td ([12, )Tj 0.212 0.212 0.208 rg -0.035 Tc 9.555 0 0 9.9 128.79 447.61 Tm (14]. )Tj 0.0363 Tc 9.9 0 0 9.9 49.42 437.05 Tm (Although )Tj 0.29 0.29 0.286 rg 0.0406 Tc 4.413 0 Td (water )Tj 0.05 Tc 9.9655 0 0 9.9 119.98 437.05 Tm (transport )Tj 0.0477 Tc 9.9 0 0 9.9 162.7 437.05 Tm (through )Tj 0.0457 Tc 3.782 0 Td (the )Tj 0.0305 Tc 1.697 0 Td (mucosa )Tj -0.0195 Tc 3.533 0 Td (is )Tj 0 Tc 0.968 0 Td (a )Tj 0.0183 Tc -22.436 -1.116 Td (possible )Tj 0.0249 Tc 3.827 0 Td (rate-l)Tj 0.114 g 0 Tc 2.272 0 Td (i)Tj 0.29 0.29 0.286 rg 0.032 Tc 0.248 0 Td (miting )Tj 0.0264 Tc 3.188 0 Td (step, )Tj 0.05 Tc 10.0824 0 0 9.9 157.82 426 Tm (another )Tj 0.0245 Tc 9.9 0 0 9.9 195.38 426 Tm (poss)Tj 0.114 g 0 Tc 1.881 0 Td (i)Tj 0.29 0.29 0.286 rg 0.007 Tc 0.3 0 Td (bility )Tj 0.212 0.212 0.208 rg -0.0195 Tc 2.609 0 Td (is )Tj 0.29 0.29 0.286 rg 0.0457 Tc 1.073 0 Td (the )Tj 0.212 0.212 0.208 rg 0.0283 Tc -21.63 -1.114 Td (limitation )Tj 0.29 0.29 0.286 rg 0.05 Tc 10.5727 0 0 9.9 86.3 414.97 Tm (of )Tj 0.0406 Tc 9.9 0 0 9.9 100.31 414.97 Tm (water )Tj 0.05 Tc 9.9655 0 0 9.9 129.58 414.97 Tm (transport )Tj 9.9203 0 0 9.9 174.14 414.97 Tm (as )Tj 0 Tc 9.9 0 0 9.9 188.54 414.97 Tm (a )Tj 0.0298 Tc 1.018 0 Td (consequence )Tj 0.05 Tc 11.1292 0 0 9.9 257.65 414.97 Tm (of )Tj 0.0242 Tc 9.9 0 0 9.9 38.79 403.93 Tm (decreased )Tj 0.0271 Tc 4.956 0 Td (blood )Tj 0.0202 Tc 3.25 0 Td (perfusion )Tj 0.0496 Tc 4.796 0 Td (to )Tj 0.0457 Tc 1.6 0 Td (the )Tj 0.0307 Tc 2.077 0 Td (airway )Tj 0.0078 Tc 3.693 0 Td (tissue. )Tj -0.035 Tc 9.5431 0 0 9.9 39.32 393.37 Tm (McFADDEN )Tj 9.7536 0 0 9.9 95.76 393.37 Tm ([16] )Tj 0.212 0.212 0.208 rg 0.05 Tc 10.0834 0 0 9.9 118.07 393.37 Tm (has )Tj 0.29 0.29 0.286 rg 0.0196 Tc 9.9 0 0 9.9 139.06 393.37 Tm (suggested )Tj 0.0208 Tc 4.861 0 Td (this )Tj 0.0352 Tc 2.222 0 Td (occurs )Tj 0.0233 Tc 3.5 0 Td (when )Tj 0.0152 Tc -20.712 -1.115 Td (cold )Tj 0.0366 Tc 2.424 0 Td (air )Tj -0.035 Tc 9.3682 0 0 9.9 80.08 382.33 Tm (is )Tj 0.114 g 0 Tc 9.9 0 0 9.9 92.08 382.33 Tm (i)Tj 0.29 0.29 0.286 rg 0.0322 Tc 0.298 0 Td (nhaled, )Tj 0.0243 Tc 3.735 0 Td (because )Tj 0.05 Tc 10.615 0 0 9.9 170.31 382.33 Tm (it )Tj 0 Tc 9.9 0 0 9.9 182.38 382.33 Tm (m)Tj 0.114 g 0.818 0 Td (i)Tj 0.29 0.29 0.286 rg 0.05 Tc 10.2181 0 0 9.9 192.87 382.33 Tm (ght )Tj 0.0445 Tc 9.9 0 0 9.9 212.54 382.33 Tm (cause )Tj 0.212 0.212 0.208 rg 0.0392 Tc 2.969 0 Td (blood )Tj 0.29 0.29 0.286 rg -0.0119 Tc -20.512 -1.116 Td (vessel )Tj 0.0282 Tc 2.707 0 Td (constriction. )Tj 0.212 0.212 0.208 rg 0.0103 Tc 5.775 0 Td (Recently, )Tj 0.29 0.29 0.286 rg 0.0135 Tc 4.319 0 Td (however, )Tj -0.035 Tc 8.4623 0 0 9.9 207.32 371.28 Tm (BAILE )Tj 0.05 Tc 10.0265 0 0 9.9 234.14 371.28 Tm (and )Tj 0.0266 Tc 9.9 0 0 9.9 252.86 371.28 Tm (co\255)Tj 0.0297 Tc -21.615 -1.114 Td (workers )Tj -0.0204 Tc 3.722 0 Td (\(17, )Tj 0.212 0.212 0.208 rg -0.035 Tc 8.8621 0 0 9.9 95.69 360.25 Tm (18] )Tj 0.29 0.29 0.286 rg 0.0343 Tc 9.9 0 0 9.9 110.26 360.25 Tm (showed )Tj 0.0149 Tc (in )Tj 0.031 Tc 4.716 0 Td (hyperventilated )Tj 0.033 Tc 6.973 0 Td (anaesthe\255)Tj 0.0004 Tc -18.901 -1.067 Td (tized )Tj 0.036 Tc 2.514 0 Td (dogs )Tj 0.05 Tc 10.215 0 0 9.9 88.78 349.69 Tm (that )Tj 0.0152 Tc 9.9 0 0 9.9 110.78 349.69 Tm (cold )Tj 0.0366 Tc 2.327 0 Td (air )Tj 0.212 0.212 0.208 rg 0.05 Tc 11.1292 0 0 9.9 150.13 349.69 Tm (or )Tj 0.0351 Tc 9.9 0 0 9.9 164.63 349.69 Tm (warm )Tj 0.29 0.29 0.286 rg 0.041 Tc 2.95 0 Td (dry )Tj 0.212 0.212 0.208 rg 0.05 Tc 10.5084 0 0 9.9 213.01 349.69 Tm (air )Tj 0.0188 Tc 9.9 0 0 9.9 230.38 349.69 Tm (tends )Tj 0.0496 Tc 2.764 0 Td (to )Tj 0.0268 Tc -22.164 -1.115 Td (increase )Tj 0.29 0.29 0.286 rg 0.0343 Tc 3.933 0 Td (tracheobronchial )Tj 0.0271 Tc 7.761 0 Td (blood )Tj 0.0332 Tc 2.91 0 Td (perfusion, )Tj 0.0209 Tc 4.797 0 Td (which )Tj 0.212 0.212 0.208 rg -0.035 Tc 9.3682 0 0 9.9 260.08 338.65 Tm (is )Tj 0.29 0.29 0.286 rg 0.0419 Tc 9.9 0 0 9.9 38.87 327.61 Tm (not )Tj 0.0319 Tc 1.793 0 Td (mediated )Tj -0.0207 Tc 4.415 0 Td (by )Tj 0.0215 Tc 1.452 0 Td (the )Tj 0.05 Tc 9.9003 0 0 9.9 131.42 327.61 Tm (autonomic )Tj 0.0306 Tc 9.9 0 0 9.9 181.43 327.61 Tm (nervous )Tj 0.0091 Tc 3.769 0 Td (system. )Tj 0.05 Tc 10.4937 0 0 9.9 253.83 327.61 Tm (To )Tj 0 Tc 9.9 0 0 9.9 38.31 316.56 Tm (d)Tj 0.114 g 0.583 0 Td (i)Tj 0.29 0.29 0.286 rg 0.0248 Tc 0.236 0 Td (stinguish )Tj 0.0126 Tc 4.33 0 Td (between )Tj 0.0252 Tc 3.88 0 Td (possible )Tj 0.0283 Tc 3.875 0 Td (mechanisms )Tj 0.212 0.212 0.208 rg 0.0493 Tc 5.723 0 Td (under )Tj 0.0068 Tc 2.9 0 Td (dif\255)Tj 0.29 0.29 0.286 rg 0.0249 Tc -21.529 -1.114 Td (ferent )Tj 0.212 0.212 0.208 rg 0.0299 Tc 3.058 0 Td (inhaled )Tj 0.29 0.29 0.286 rg 0.0444 Tc 3.685 0 Td (gas )Tj 0.0407 Tc 1.937 0 Td (conditions )Tj 0.0367 Tc 5.089 0 Td (\(hot, )Tj 0.0468 Tc 2.62 0 Td (co)Tj 0.114 g 0 Tc 1.02 0 Td (l)Tj 0.212 0.212 0.208 rg 0.241 0 Td (d )Tj 0.29 0.29 0.286 rg 0.0355 Tc 1.163 0 Td (and )Tj 0.0323 Tc 2.134 0 Td (dry\), )Tj 0.0204 Tc -20.896 -1.067 Td (investigators )Tj -0.0313 Tc 6.407 0 Td (will )Tj 0.0353 Tc 2.57 0 Td (have )Tj 0.0496 Tc 3.054 0 Td (to )Tj 0.05 Tc 9.9803 0 0 9.9 176.62 294.97 Tm (make )Tj 0.0343 Tc 9.9 0 0 9.9 210.1 294.97 Tm (simultaneous )Tj 0.0319 Tc -17.345 -1.115 Td (measurements )Tj 0.05 Tc 10.1333 0 0 9.9 104.63 283.93 Tm (not )Tj 0.0286 Tc 9.9 0 0 9.9 124.22 283.93 Tm (only )Tj 0.05 Tc 11.1292 0 0 9.9 148.69 283.93 Tm (of )Tj 0.0421 Tc 9.9 0 0 9.9 163.66 283.93 Tm (temperature )Tj 0.05 Tc 10.0265 0 0 9.9 220.7 283.93 Tm (and )Tj 0.0406 Tc 9.9 0 0 9.9 242.39 283.93 Tm (water )Tj 0.038 Tc -20.607 -1.115 Td (vapour, )Tj 0.05 Tc 10.18 0 0 9.9 73.93 272.89 Tm (but )Tj 0.0168 Tc 9.9 0 0 9.9 90.62 272.89 Tm (also )Tj /T1_2 1 Tf -0.035 Tc 9.9306 0 0 10 110.28 272.89 Tm (in )Tj 0.0166 Tc 10 0 0 10 120.03 272.89 Tm (situ )Tj /T1_0 1 Tf 0.0363 Tc 9.9 0 0 9.9 137.74 272.89 Tm (measurements )Tj 0.05 Tc 11.1292 0 0 9.9 201.01 272.89 Tm (of )Tj 0.0398 Tc 9.9 0 0 9.9 212.14 272.89 Tm (mucus )Tj 0.212 0.212 0.208 rg 0.0406 Tc 3.056 0 Td (water )Tj 0.29 0.29 0.286 rg 0.0467 Tc -20.664 -1.116 Td (content )Tj 0.05 Tc 10.3398 0 0 9.9 72.85 261.84 Tm (and )Tj 11.1292 0 0 9.9 92.53 261.84 Tm (of )Tj 0.0392 Tc 9.9 0 0 9.9 105.13 261.84 Tm (blood )Tj 0.212 0.212 0.208 rg -0.0191 Tc 2.8 0 Td (flow )Tj 0.0011 Tc 2.239 0 Td (to )Tj 0.29 0.29 0.286 rg 0.0215 Tc 1.212 0 Td (the )Tj 0.0307 Tc 1.64 0 Td (airway )Tj 0.017 Tc 3.257 0 Td (tissues)Tj 0.114 g 0 Tc 2.793 0 Td (. )Tj 0.29 0.29 0.286 rg /T1_2 1 Tf -0.0003 Tc 10 0 0 10 38.38 234.97 Tm (Significance )Tj 0.05 Tc 10.1131 0 0 10 89.81 234.97 Tm (for )Tj 10.5719 0 0 10 106.83 234.97 Tm (CF )Tj /T1_0 1 Tf 9.9723 0 0 9.9 47.43 218.16 Tm (The )Tj 0.0365 Tc 9.9 0 0 9.9 70 218.16 Tm (greatest )Tj 0.0371 Tc 3.937 0 Td (potential )Tj 0.0364 Tc 4.412 0 Td (problem )Tj 0.0377 Tc 4.205 0 Td (for )Tj 0.05 Tc 11.1325 0 0 9.9 212.52 218.16 Tm (CF )Tj 0.0218 Tc 9.9 0 0 9.9 232.18 218.16 Tm (subjects )Tj 0.0188 Tc -19.623 -1.066 Td (would )Tj 0.0246 Tc 2.852 0 Td (occu)Tj 0.114 g 0 Tc 2.045 0 Td (r )Tj 0.29 0.29 0.286 rg 0.0247 Tc 0.62 0 Td (from )Tj 0.0333 Tc 2.282 0 Td (inhaling )Tj 0.05 Tc 10.1124 0 0 9.9 152.06 207.61 Tm (dry )Tj 10.0881 0 0 9.9 168.86 207.61 Tm (air )Tj 0.0477 Tc 9.9 0 0 9.9 183.34 207.61 Tm (through )Tj 0.05 Tc 10.2 0 0 9.9 219.34 207.61 Tm (the )Tj 0.0413 Tc 9.9 0 0 9.9 235.18 207.61 Tm (mouth. )Tj 0.0438 Tc -19.982 -1.115 Td (This )Tj -0.035 Tc 9.3682 0 0 9.9 59.44 196.57 Tm (is )Tj 0.0196 Tc 9.9 0 0 9.9 68.5 196.57 Tm (suggested )Tj -0.0207 Tc 4.476 0 Td (by )Tj 0.0457 Tc 1.306 0 Td (the )Tj 0.05 Tc 10.377 0 0 9.9 141.5 196.57 Tm (data )Tj 11.1292 0 0 9.9 163.57 196.57 Tm (of )Tj -0.035 Tc 8.78 0 0 9.9 175.64 196.57 Tm (FREED )Tj /T1_2 1 Tf 0.05 Tc 10.6747 0 0 10 204.86 196.57 Tm (eta/. )Tj /T1_0 1 Tf -0.035 Tc 9.7536 0 0 9.9 229.2 196.57 Tm ([19] )Tj 0.212 0.212 0.208 rg 0.0382 Tc 9.9 0 0 9.9 247.67 196.57 Tm (who )Tj 0.29 0.29 0.286 rg 0.0301 Tc -21.198 -1.116 Td (found )Tj 0.05 Tc 10.215 0 0 9.9 69.58 185.52 Tm (that )Tj 0.0383 Tc 9.9 0 0 9.9 93.5 185.52 Tm (concentrations )Tj 0.05 Tc 11.1292 0 0 9.9 163.09 185.52 Tm (of )Tj 0.0259 Tc 9.9 0 0 9.9 178.45 185.52 Tm (epithelial )Tj -0.0038 Tc 4.656 0 Td (cells )Tj 0.05 Tc 10.3398 0 0 9.9 249.49 185.52 Tm (and )Tj 0.0335 Tc 9.9 0 0 9.9 37.94 174.49 Tm (prostaglandins )Tj 0.0149 Tc 6.632 0 Td (in )Tj 0.0457 Tc 1.267 0 Td (the )Tj 0.0249 Tc 1.691 0 Td (lavage )Tj 0.0427 Tc 3.097 0 Td (subsequent )Tj 0.0496 Tc 5.2 0 Td (to )Tj 0 Tc 1.253 0 Td (a )Tj 0.212 0.212 0.208 rg 0.874 0 Td (d)Tj 0.114 g 0.59 0 Td (r)Tj 0.29 0.29 0.286 rg 0.388 0 Td (y )Tj 0.05 Tc 10.0881 0 0 9.9 254.3 174.49 Tm (air )Tj 0.0212 Tc 9.9 0 0 9.9 37.34 163.93 Tm (challenge )Tj 0.0009 Tc 4.276 0 Td (were )Tj 0.05 Tc 9.9428 0 0 9.9 101.74 163.93 Tm (much )Tj 0.0415 Tc 9.9 0 0 9.9 128.08 163.93 Tm (greater )Tj 0.05 Tc 10.0233 0 0 9.9 160.78 163.93 Tm (than )Tj 0.0309 Tc 9.9 0 0 9.9 182.86 163.93 Tm (those )Tj 0.05 Tc 9.9904 0 0 9.9 207.74 163.93 Tm (after )Tj 0 Tc 9.9 0 0 9.9 230.3 163.93 Tm (a )Tj 0.212 0.212 0.208 rg 0.0413 Tc 0.785 0 Td (humid )Tj 0.29 0.29 0.286 rg 0.05 Tc 10.0881 0 0 9.9 37.34 152.89 Tm (air )Tj 0.018 Tc 9.9 0 0 9.9 51.74 152.89 Tm (challenge. )Tj 0.212 0.212 0.208 rg 0.05 Tc 10.1704 0 0 9.9 97.39 152.89 Tm (Hot, )Tj 0.041 Tc 9.9 0 0 9.9 120.39 152.89 Tm (dry )Tj 0.29 0.29 0.286 rg 0 Tc 1.793 0 Td (a)Tj 0.114 g 0.487 0 Td (i)Tj 0.29 0.29 0.286 rg 0.298 0 Td (r )Tj 0.0309 Tc 0.679 0 Td (would )Tj 0.0376 Tc 3.006 0 Td (require )Tj 0.0215 Tc 3.441 0 Td (the )Tj 0.0365 Tc 1.594 0 Td (greatest )Tj 0.0216 Tc -19.629 -1.115 Td (humidification )Tj 0.05 Tc 10.3398 0 0 9.9 102.61 141.85 Tm (and )Tj 9.9168 0 0 9.9 123.35 141.85 Tm (rate )Tj 11.1292 0 0 9.9 143.41 141.85 Tm (of )Tj 0.212 0.212 0.208 rg 0.0406 Tc 9.9 0 0 9.9 156.47 141.85 Tm (water )Tj 0.29 0.29 0.286 rg 0.05 Tc 10.087 0 0 9.9 183.82 141.85 Tm (transport )Tj 0.0409 Tc 9.9 0 0 9.9 227.41 141.85 Tm (from )Tj 0.0215 Tc 2.579 0 Td (the )Tj 0.021 Tc -21.778 -1.116 Td (airway )Tj 0.114 g 0 Tc 3.202 0 Td (l)Tj 0.29 0.29 0.286 rg 0.0239 Tc 0.291 0 Td (ining )Tj 0.0369 Tc 2.473 0 Td (into )Tj 0.0457 Tc 2.042 0 Td (the )Tj 0.0109 Tc 1.594 0 Td (gas. )Tj 0.05 Tc 10.5834 0 0 9.9 152.05 130.8 Tm (Our )Tj 0.212 0.212 0.208 rg 10.1109 0 0 9.9 172.7 130.8 Tm (data )Tj 0.0288 Tc 9.9 0 0 9.9 194.8 130.8 Tm (indicate )Tj 0.29 0.29 0.286 rg 0.05 Tc 10.215 0 0 9.9 231.82 130.8 Tm (that )Tj 10.7486 0 0 9.9 251.89 130.8 Tm (CF )Tj 0.0149 Tc 9.9 0 0 9.9 37.3 120.25 Tm (subjects )Tj 0.05 Tc 9.9553 0 0 9.9 74.78 120.25 Tm (cannot )Tj 0.0291 Tc 9.9 0 0 9.9 108.38 120.25 Tm (accomplish )Tj 0.0046 Tc 5.341 0 Td (this )Tj 0.0033 Tc 1.931 0 Td (as )Tj -0.035 Tc 9.8413 0 0 9.9 193.91 120.25 Tm (well )Tj 0.0033 Tc 9.9 0 0 9.9 214.94 120.25 Tm (as )Tj 0.212 0.212 0.208 rg 0.0313 Tc 1.367 0 Td (normals, )Tj 0.0088 Tc -19.297 -1.116 Td (which )Tj 0.29 0.29 0.286 rg 0.0392 Tc 2.811 0 Td (may )Tj -0.0122 Tc 2.136 0 Td (be )Tj 0.0301 Tc 1.25 0 Td (associated )Tj 0.0398 Tc 4.664 0 Td (with )Tj 0.05 Tc 9.9224 0 0 9.9 166.46 109.2 Tm (abnormal )Tj 0.0366 Tc 9.9 0 0 9.9 210.74 109.2 Tm (properties )Tj 0.05 Tc 11.1292 0 0 9.9 256.69 109.2 Tm (of )Tj 0.0215 Tc 9.9 0 0 9.9 37.42 98.16 Tm (the )Tj 0.0206 Tc 1.6 0 Td (mucus. )Tj 0.039 Tc 3.337 0 Td (Cold, )Tj 0.212 0.212 0.208 rg 0.05 Tc 10.1124 0 0 9.9 112.7 98.16 Tm (dry )Tj 0.29 0.29 0.286 rg 10.0881 0 0 9.9 130.46 98.16 Tm (air )Tj 0.212 0.212 0.208 rg 0.0252 Tc 9.9 0 0 9.9 145.43 98.16 Tm (requires )Tj -0.0094 Tc 3.726 0 Td (less )Tj 0.029 Tc 1.849 0 Td (humidification)Tj 0.423 0.423 0.416 rg 0 Tc 6.289 0 Td (, )Tj 0.29 0.29 0.286 rg 0.0451 Tc -22.772 -1.115 Td (but )Tj 0.0406 Tc 1.695 0 Td (water )Tj 0.0247 Tc 2.658 0 Td (availability )Tj 0.0392 Tc 5.099 0 Td (may )Tj 0.033 Tc 2.125 0 Td (also )Tj 0.0363 Tc 2.047 0 Td (be )Tj 0.212 0.212 0.208 rg 0.012 Tc 1.3 0 Td (lower. )Tj 0.05 Tc 9.9506 0 0 9.9 214.49 87.12 Tm (In )Tj 0.29 0.29 0.286 rg 10.0265 0 0 9.9 226.46 87.12 Tm (any )Tj 0.0221 Tc 9.9 0 0 9.9 244.7 87.12 Tm (case, )Tj 0.212 0.212 0.208 rg 0.0325 Tc -20.993 -1.115 Td (drying )Tj 0.29 0.29 0.286 rg 0.05 Tc 11.1292 0 0 9.9 68.53 76.08 Tm (of )Tj 0.0215 Tc 9.9 0 0 9.9 82.06 76.08 Tm (the )Tj 0.0499 Tc 1.697 0 Td (mucosa )Tj 0.05 Tc 10.311 0 0 9.9 135.34 76.08 Tm (may )Tj 0.212 0.212 0.208 rg 0.0164 Tc 9.9 0 0 9.9 158.8 76.08 Tm (lead )Tj 0.29 0.29 0.286 rg 0.05 Tc 10.4772 0 0 9.9 180.45 76.08 Tm (to )Tj 0.0404 Tc 9.9 0 0 9.9 193.34 76.08 Tm (airway )Tj 0.212 0.212 0.208 rg 0.0392 Tc 3.396 0 Td (irritation )Tj 0.29 0.29 0.286 rg 0.05 Tc 10.3398 0 0 9.9 291.73 730.33 Tm (and )Tj 0.212 0.212 0.208 rg 0.0225 Tc 9.9 0 0 9.9 310.07 730.33 Tm (reduced )Tj 0.29 0.29 0.286 rg 0.0277 Tc 3.587 0 Td (mucociliary )Tj 0.0245 Tc 5.277 0 Td (clearance. )Tj 0.0438 Tc 4.511 0 Td (This )Tj 0.212 0.212 0.208 rg 0.05 Tc 10.0466 0 0 9.9 464.14 730.33 Tm (may )Tj 0.29 0.29 0.286 rg 0.0443 Tc 9.9 0 0 9.9 485.18 730.33 Tm (occur )Tj 0.0496 Tc 2.675 0 Td (to )Tj 0 Tc -22.263 -1.068 Td (a )Tj 0.0415 Tc 0.875 0 Td (greater )Tj 0.0396 Tc 3.342 0 Td (extent )Tj 0.212 0.212 0.208 rg 0.0149 Tc 3.009 0 Td (in )Tj 0.29 0.29 0.286 rg 0.05 Tc 10.7486 0 0 9.9 374.29 719.76 Tm (CF )Tj 0.0218 Tc 9.9 0 0 9.9 391.54 719.76 Tm (subjects )Tj 0.05 Tc 10.0265 0 0 9.9 428.54 719.76 Tm (and )Tj 0.044 Tc 9.9 0 0 9.9 447.74 719.76 Tm (could )Tj 0.05 Tc 9.9645 0 0 9.9 475.58 719.76 Tm (contribute )Tj 0.0496 Tc 9.9 0 0 9.9 291.82 708.73 Tm (to )Tj 0.0457 Tc 1.212 0 Td (the )Tj 0.212 0.212 0.208 rg 0.0376 Tc 1.641 0 Td (development )Tj 0.29 0.29 0.286 rg 0.05 Tc 11.1292 0 0 9.9 377.65 708.73 Tm (of )Tj 0.212 0.212 0.208 rg 0.0279 Tc 9.9 0 0 9.9 390.22 708.73 Tm (their )Tj 0.05 Tc 9.964 0 0 9.9 412.82 708.73 Tm (pulmonary )Tj 0.29 0.29 0.286 rg 0.0107 Tc 9.9 0 0 9.9 463.59 708.73 Tm (disease. )Tj 0.212 0.212 0.208 rg -0.035 Tc 9.4505 0 0 9.8 385.4 677.53 Tm (Refe)Tj 0.114 g 0 Tc 9.8 0 0 9.8 402.23 677.53 Tm (r)Tj 0.29 0.29 0.286 rg -0.035 Tc 9.7948 0 0 9.8 405.02 677.53 Tm (ences )Tj 0 Tc 8.4 0 0 8.4 292.26 662.17 Tm (I)Tj 0.423 0.423 0.416 rg 0.387 0 Td (. )Tj 0.29 0.29 0.286 rg 0.0069 Tc 1.217 0 Td (Wood )Tj -0.019 Tc 2.913 0 Td (RE, )Tj 0.212 0.212 0.208 rg 0.0071 Tc 1.943 0 Td (Boat )Tj 0.29 0.29 0.286 rg 0.0431 Tc 2.225 0 Td (TF, )Tj 0.0185 Tc 1.889 0 Td (Doershuk )Tj 0.05 Tc 8.8292 0 0 8.4 417.51 662.17 Tm (CF)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 428.95 662.17 Tm (. )Tj ET BT /Suspect <>BDC 0.553 0.557 0.545 rg /T1_0 1 Tf 8.4 0 0 8.4 433.822 662.17 Tm (-)Tj 0.29 0.29 0.286 rg 0.0239 Tc 0.908 0 Td (State )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.9033 0 0 8.4 462.15 662.17 Tm (of )Tj 0.0197 Tc 8.4 0 0 8.4 472.3 662.17 Tm (the )Tj 0.0175 Tc 1.593 0 Td (art: )Tj -0.0046 Tc 1.771 0 Td (cystic )Tj -0.0155 Tc -24.916 -1.086 Td (fibrosis. )Tj /T1_2 1 Tf 0.05 Tc 8.3646 0 0 8 321.25 653.05 Tm (Am )Tj 0.0335 Tc 8 0 0 8 335.58 653.05 Tm (Rev )Tj ET BT /Suspect <>BDC /T1_2 1 Tf 0.007 Tc 8 0 0 8 351.42 653.05 Tm (Respir )Tj EMC ET BT /T1_2 1 Tf 0.0128 Tc 8 0 0 8 374.956 653.05 Tm (Dis, )Tj /T1_0 1 Tf -0.035 Tc 8.1597 0 0 8.4 391.88 653.05 Tm (1976)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 406.91 653.05 Tm (, )Tj 0.29 0.29 0.286 rg -0.035 Tc 7.7728 0 0 8.4 412.53 653.05 Tm (113)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 424.19 653.05 Tm (, )Tj 0.29 0.29 0.286 rg 0.512 0 Td (8)Tj 0.423 0.423 0.416 rg 0.52 0 Td (3)Tj 0.29 0.29 0.286 rg 0.457 0 Td (3)Tj 0.624 0.624 0.612 rg 0.4 0 Td (-)Tj 0.29 0.29 0.286 rg -0.0193 Tc 0.623 0 Td (878. )Tj 0 Tc -18.331 -1.029 Td (2)Tj 0.423 0.423 0.416 rg (. )Tj 0.212 0.212 0.208 rg 0.0013 Tc 1.715 0 Td (Boucher )Tj 0.29 0.29 0.286 rg 0.0417 Tc 3.714 0 Td (RC)Tj 0.423 0.423 0.416 rg 0 Tc (, )Tj 0.29 0.29 0.286 rg -0.0109 Tc 2 0 Td (Knowles )Tj 0.212 0.212 0.208 rg 0.0171 Tc 3.886 0 Td (MR, )Tj 0.29 0.29 0.286 rg 0.0203 Tc 2.223 0 Td (Cotton )Tj 0 Tc 3.2 0 Td (C)Tj 0.423 0.423 0.416 rg 0.681 0 Td (, )Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_0 1 Tf 0.0369 Tc 8.4 0 0 8.4 442.4096 644.4064 Tm (Stutt)Tj 0.423 0.423 0.416 rg 0 Tc 2.004 0 Td (s )Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf 0.0413 Tc 8.4 0 0 8.4 465.56 644.4064 Tm (MJ, )Tj 0.0241 Tc 1.945 0 Td (Yankaskas )Tj 0.0373 Tc -22.689 -1.086 Td (JR, )Tj 0.0218 Tc 1.654 0 Td (Gatzy )Tj 0.0081 Tc 2.746 0 Td (JT. )Tj 0.553 0.557 0.545 rg 0 Tc 1.594 0 Td (-)Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_0 1 Tf 0.0002 Tc 8.4 0 0 8.4 348.884 635.284 Tm (On )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.4 0 0 8.4 361.8452 635.284 Tm (a )Tj -0.0335 Tc 0.81 0 Td (unified )Tj 0.0042 Tc 3.026 0 Td (theory )Tj 0.05 Tc 8.9033 0 0 8.4 417.99 635.29 Tm (of )Tj -0.0046 Tc 8.4 0 0 8.4 427.12 635.29 Tm (cystic )Tj -0.0147 Tc 2.627 0 Td (fibrosis )Tj 0.212 0.212 0.208 rg 0.0223 Tc 3.202 0 Td (lung )Tj 0.29 0.29 0.286 rg -0.0056 Tc 2.056 0 Td (disease. )Tj /T1_3 1 Tf 0.05 Tc 7.6964 0 0 7.5001 291.23 626.65 Tm (In)Tj 0.423 0.423 0.416 rg 0 Tc 7.5001 0 0 7.5001 298.44 626.65 Tm (: )Tj 0.29 0.29 0.286 rg /T1_0 1 Tf -0.0032 Tc 8.4 0 0 8.4 304.23 626.65 Tm (Cystic )Tj 0.0006 Tc 2.92 0 Td (Fibrosis: )Tj -0.0014 Tc 3.946 0 Td (horizons)Tj 0.423 0.423 0.416 rg 0 Tc 3.524 0 Td (. )Tj 0.29 0.29 0.286 rg 0.644 0 Td (D)Tj 0.423 0.423 0.416 rg 0.785 0 Td (. )Tj 0.29 0.29 0.286 rg -0.0018 Tc 0.643 0 Td (Lawson )Tj -0.009 Tc 3.538 0 Td (ed)Tj 0.423 0.423 0.416 rg 0 Tc 1.019 0 Td (.)Tj 0.29 0.29 0.286 rg 0.233 0 Td (, )Tj 0.212 0.212 0.208 rg -0.011 Tc 0.64 0 Td (Wiley, )Tj 0.29 0.29 0.286 rg -0.0292 Tc 3.094 0 Td (New )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0256 Tc 8.4 0 0 8.4 499.1688 626.65 Tm (York, )Tj EMC ET BT 0.212 0.212 0.208 rg /T1_0 1 Tf -0.035 Tc 8.1597 0 0 8.4 292.04 617.53 Tm (1984)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 307.07 617.53 Tm (, )Tj 0.29 0.29 0.286 rg 0.0376 Tc 0.588 0 Td (pp)Tj 0.423 0.423 0.416 rg 0 Tc 1.064 0 Td (. )Tj 0.29 0.29 0.286 rg -0.035 Tc 7.7728 0 0 8.4 326.61 617.53 Tm (167)Tj 0.553 0.557 0.545 rg 0 Tc 8.4 0 0 8.4 337.34 617.53 Tm (-)Tj 0.29 0.29 0.286 rg -0.035 Tc 8.236 0 0 8.4 342.92 617.53 Tm (177. )Tj 7.7865 0 0 8.4 291.27 608.89 Tm (3. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0123 Tc 8.4 0 0 8.4 305.13 608.89 Tm (Saidel )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.6334 0 0 8.4 327.75 608.89 Tm (GM, )Tj 0.0181 Tc 8.4 0 0 8.4 347 608.89 Tm (Kruse )Tj 0.212 0.212 0.208 rg -0.0185 Tc 2.743 0 Td (KL, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0014 Tc 8.4 0 0 8.4 385.8836 608.89 Tm (Primiano )Tj EMC /Suspect <>BDC 0.29 0.29 0.286 rg 0.048 Tc 4 0 Td (FP )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.7976 0 0 8.4 431.47 608.89 Tm (Jr)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 438.55 608.89 Tm (.)Tj 0.29 0.29 0.286 rg 0.465 0 Td (-)Tj 0.0218 Tc 0.807 0 Td (Model )Tj 0.0104 Tc 2.962 0 Td (simulation )Tj 0.05 Tc 8.9033 0 0 8.4 512.56 608.89 Tm (of )Tj -0.0007 Tc 8.4 0 0 8.4 291.35 599.76 Tm (heat )Tj 0.0269 Tc 2.049 0 Td (and )Tj 0.0038 Tc 1.894 0 Td (water )Tj 0.0206 Tc 2.627 0 Td (transport )Tj -0.0069 Tc 4.107 0 Td (dynamics )Tj -0.035 Tc 7.9356 0 0 8.4 416.1 599.76 Tm (in )Tj 0.0395 Tc 8.4 0 0 8.4 425.2 599.76 Tm (an )Tj 0.0024 Tc 1.371 0 Td (airway. )Tj /T1_3 1 Tf 0 Tc 8 0 0 8 465.05 599.76 Tm (J )Tj /T1_2 1 Tf 0.0174 Tc 0.916 0 Td (Biomech )Tj -0.0043 Tc 4.02 0 Td (Eng, )Tj /T1_0 1 Tf -0.035 Tc 8.241 0 0 8.4 292.04 591.12 Tm (1983, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 8.236 0 0 8.4 312.68 591.12 Tm (105, )Tj EMC /Suspect <>BDC 8.1261 0 0 8.4 329.48 591.12 Tm (180)Tj 0.624 0.624 0.612 rg 0 Tc 8.4 0 0 8.4 340.7 591.12 Tm (-)Tj 0.212 0.212 0.208 rg -0.035 Tc 7.9309 0 0 8.4 346.29 591.12 Tm (193. )Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf 8.2321 0 0 8.4 290.85 582 Tm (4. )Tj -0.0133 Tc 8.4 0 0 8.4 305.72 582 Tm (Deal )Tj -0.006 Tc 2.342 0 Td (EC )Tj 0.0324 Tc 1.6 0 Td (Jr, )Tj 0.0113 Tc 1.544 0 Td (McFadden )Tj -0.006 Tc 4.856 0 Td (ER )Tj 0.212 0.212 0.208 rg 0.0038 Tc 1.714 0 Td (Jr, )Tj 0.0086 Tc 1.485 0 Td (Ingram )Tj 0.05 Tc 8.6927 0 0 8.4 448.28 582 Tm (RH )Tj 8.5727 0 0 8.4 463.63 582 Tm (Jr, )Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_0 1 Tf 0.0198 Tc 8.4 0 0 8.4 476.01 582 Tm (Strauss )Tj EMC ET BT 0.212 0.212 0.208 rg /T1_0 1 Tf 0.0393 Tc 8.4 0 0 8.4 504.9228 582 Tm (RH, )Tj 0.29 0.29 0.286 rg 0.0057 Tc -25.487 -1.085 Td (Jaeger )Tj 0.0301 Tc 2.971 0 Td (JJ)Tj 0.423 0.423 0.416 rg 0 Tc 0.9 0 Td (. )Tj 0.553 0.557 0.545 rg 0.637 0 Td (-)Tj 0.29 0.29 0.286 rg 0.0007 Tc 0.979 0 Td (Role )Tj 0.05 Tc 9.4598 0 0 8.4 356.07 572.89 Tm (of )Tj 0.0072 Tc 8.4 0 0 8.4 367.19 572.89 Tm (respiratory )Tj -0.0007 Tc 4.857 0 Td (heat )Tj 0.0027 Tc 2.048 0 Td (exchange )Tj -0.018 Tc 4.231 0 Td (in )Tj 0.0215 Tc 1.21 0 Td (production )Tj 0.05 Tc 8.9033 0 0 8.4 512.56 572.89 Tm (of )Tj -0.0117 Tc 8.4 0 0 8.4 290.79 564.24 Tm (exercise-induced )Tj 0.0125 Tc 6.915 0 Td (asthma. )Tj /T1_3 1 Tf 0 Tc 8 0 0 8 377.69 564.24 Tm (J )Tj /T1_2 1 Tf 0.0326 Tc 0.864 0 Td (Appf )Tj 0.019 Tc 2.213 0 Td (Physiof)Tj 0.423 0.423 0.416 rg 0 Tc 3.095 0 Td (: )Tj 0.29 0.29 0.286 rg 0.014 Tc 0.625 0 Td (Respirat )Tj 0.0013 Tc 3.84 0 Td (Environ )Tj 0.03 Tc 3.48 0 Td (Exercise )Tj 0.009 Tc -24.9 -1.14 Td (Physiol)Tj 0.423 0.423 0.416 rg 0 Tc 3.056 0 Td (, )Tj 0.212 0.212 0.208 rg /T1_0 1 Tf -0.035 Tc 8.1597 0 0 8.4 321.32 555.12 Tm (1979)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 336.83 555.12 Tm (, )Tj 0.212 0.212 0.208 rg -0.0133 Tc 0.526 0 Td (46 )Tj 0.29 0.29 0.286 rg -0.0086 Tc 1.249 0 Td (\(3\), )Tj 0.0128 Tc 1.665 0 Td (467-475. )Tj /T1_2 1 Tf -0.035 Tc 7.5657 0 0 8 291.28 546.48 Tm (5. )Tj /T1_0 1 Tf 0.0021 Tc 8.4 0 0 8.4 305.22 546.48 Tm (Ingelstedl )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0286 Tc 8.4 0 0 8.4 343.0536 546.48 Tm (S. )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.4 0 0 8.4 354.6204 546.48 Tm (-)Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0011 Tc 8.4 0 0 8.4 364.1712 546.48 Tm (Studies )Tj EMC ET BT /T1_0 1 Tf 0.049 Tc 8.4 0 0 8.4 393.5208 546.48 Tm (on )Tj -0.0088 Tc 1.664 0 Td (the )Tj 0.0154 Tc 1.764 0 Td (conditioning )Tj 0.05 Tc 8.9033 0 0 8.4 471.27 546.48 Tm (of )Tj 0.0219 Tc 8.4 0 0 8.4 483.28 546.48 Tm (air )Tj -0.018 Tc 1.658 0 Td (in )Tj 0.0483 Tc 1.377 0 Td (the )Tj 0.0072 Tc -25.885 -1.086 Td (respiratory )Tj -0.0041 Tc 4.799 0 Td (tract. )Tj /T1_2 1 Tf 0.05 Tc 8.0193 0 0 8 351.96 537.36 Tm (Acta )Tj -0.0231 Tc 8 0 0 8 370.01 537.36 Tm (oJOiaryngol)Tj 0.423 0.423 0.416 rg 0 Tc 4.812 0 Td (, )Tj 0.29 0.29 0.286 rg /T1_0 1 Tf -0.035 Tc 8.1597 0 0 8.4 413.96 537.36 Tm (1956)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 429.47 537.36 Tm (, )Tj 0.29 0.29 0.286 rg -0.035 Tc 7.9309 0 0 8.4 435.09 537.36 Tm (131, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0007 Tc 8.4 0 0 8.4 451.1 537.36 Tm (\(Suppl.\), )Tj EMC /Suspect <>BDC 0 Tc 3.977 0 Td (1)Tj 0.423 0.423 0.416 rg 0.308 0 Td (-)Tj 0.29 0.29 0.286 rg -0.035 Tc 8.3851 0 0 8.4 492.33 537.36 Tm (80. )Tj EMC ET BT /T1_0 1 Tf 0 Tc 8.4 0 0 8.4 290.78 528.73 Tm (6)Tj 0.423 0.423 0.416 rg 0.506 0 Td (. )Tj 0.29 0.29 0.286 rg 0.0136 Tc 1.152 0 Td (Cumming )Tj 0.0145 Tc 4.515 0 Td (G, )Tj -0.0091 Tc 1.492 0 Td (Warwick )Tj 0 Tc 4.114 0 Td (W)Tj 0.423 0.423 0.416 rg 0.955 0 Td (. )Tj 0.624 0.624 0.612 rg 0.637 0 Td (-)Tj 0.29 0.29 0.286 rg 0.0205 Tc 0.98 0 Td (Water )Tj 0.0288 Tc 2.973 0 Td (vapour )Tj -0.0007 Tc 3.373 0 Td (handJing )Tj -0.035 Tc 7.9356 0 0 8.4 498.66 528.73 Tm (in )Tj 0.0197 Tc 8.4 0 0 8.4 508.78 528.73 Tm (the )Tj -0.0045 Tc -25.95 -1.086 Td (airways. )Tj ET BT /Suspect <>BDC /T1_2 1 Tf 0.0355 Tc 8 0 0 8 321.68 519.61 Tm (In)Tj 0.423 0.423 0.416 rg 0 Tc 0.933 0 Td (: )Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf 0.05 Tc 8.5058 0 0 8.4 333.53 519.61 Tm (The )Tj 0.212 0.212 0.208 rg 0.0032 Tc 8.4 0 0 8.4 350.33 519.61 Tm (lung )Tj 0.29 0.29 0.286 rg 0.0269 Tc 2.056 0 Td (and )Tj -0.0349 Tc 1.887 0 Td (its )Tj 0.0083 Tc 1.198 0 Td (environment, )Tj 0.0145 Tc 5.715 0 Td (G. )Tj 0.212 0.212 0.208 rg -0.0017 Tc 1.433 0 Td (Bonsignore )Tj 0.29 0.29 0.286 rg 0.05 Tc 8.4599 0 0 8.4 494.79 519.61 Tm (and )Tj 0.0145 Tc 8.4 0 0 8.4 510.64 519.61 Tm (G. )Tj 0.423 0.423 0.416 rg 0 Tc -26.173 -1.029 Td (C)Tj 0.29 0.29 0.286 rg 0.0082 Tc 0.696 0 Td (umming )Tj 0.001 Tc 3.646 0 Td (eds)Tj 0.423 0.423 0.416 rg 0 Tc 1.367 0 Td (, )Tj 0.29 0.29 0.286 rg -0.0051 Tc 0.582 0 Td (Plenum, )Tj -0.035 Tc 8.1891 0 0 8.4 374.44 510.97 Tm (New )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0256 Tc 8.4 0 0 8.4 392.14 510.97 Tm (York, )Tj EMC ET BT /T1_0 1 Tf -0.035 Tc 8.241 0 0 8.4 415.88 510.97 Tm (1982, )Tj 0.0376 Tc 8.4 0 0 8.4 436.33 510.97 Tm (pp)Tj 0.423 0.423 0.416 rg 0 Tc 1.064 0 Td (. )Tj 0.29 0.29 0.286 rg -0.0173 Tc 0.523 0 Td (379)Tj 0.553 0.557 0.545 rg 0 Tc 1.486 0 Td (-)Tj 0.29 0.29 0.286 rg -0.035 Tc 8.3577 0 0 8.4 466.94 510.97 Tm (393. )Tj 7.6478 0 0 8.4 290.8 501.84 Tm (7. )Tj 0.212 0.212 0.208 rg 0.0183 Tc 8.4 0 0 8.4 305.24 501.84 Tm (Ferrus )Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_0 1 Tf 0 Tc 8.4 0 0 8.4 331.6328 501.84 Tm (L)Tj 0.423 0.423 0.416 rg 0.562 0 Td (, )Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf 0.029 Tc 8.4 0 0 8.4 342.1664 501.84 Tm (Guenard )Tj ET BT /Suspect <>BDC 0.212 0.212 0.208 rg /T1_0 1 Tf 0.0106 Tc 8.4 0 0 8.4 376.766 501.84 Tm (H, )Tj EMC /Suspect <>BDC 0.29 0.29 0.286 rg 0.0074 Tc 1.488 0 Td (Vardon )Tj EMC ET BT /T1_0 1 Tf 0.0145 Tc 8.4 0 0 8.4 418.4888 501.84 Tm (G, )Tj ET BT /Suspect <>BDC 0.212 0.212 0.208 rg /T1_0 1 Tf -0.004 Tc 8.4 0 0 8.4 431.5088 501.84 Tm (Varene )Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf -0.035 Tc 8.2578 0 0 8.4 459.32 501.84 Tm (P. )Tj 0 Tc 8.4 0 0 8.4 469.82 501.84 Tm (-)Tj 0.0141 Tc 1.093 0 Td (Respiratory )Tj 0.0038 Tc -22.396 -1.086 Td (water )Tj -0.0189 Tc 2.564 0 Td (loss. )Tj /T1_2 1 Tf 0.007 Tc 8 0 0 8 330.3 492.72 Tm (Respir )Tj 0.0062 Tc 3.06 0 Td (Physiol, )Tj ET BT /Suspect <>BDC 0.212 0.212 0.208 rg /T1_0 1 Tf -0.035 Tc 8.0056 0 0 8.4 384.68 492.72 Tm (1980, )Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf 8.3983 0 0 8.4 404.54 492.72 Tm (39, )Tj 8.2694 0 0 8.4 417.5 492.72 Tm (367)Tj 0.624 0.624 0.612 rg 0 Tc 8.4 0 0 8.4 429.5 492.72 Tm (-)Tj 0.29 0.29 0.286 rg -0.035 Tc 8.3577 0 0 8.4 434.3 492.72 Tm (381. )Tj 7.7659 0 0 8.4 290.74 484.09 Tm (8. )Tj 0.0195 Tc 8.4 0 0 8.4 305.24 484.09 Tm (McFadden )Tj 0.05 Tc 8.4073 0 0 8.4 347.95 484.09 Tm (ER )Tj 0.0324 Tc 8.4 0 0 8.4 364.75 484.09 Tm (Jr, )Tj 0.0095 Tc 1.658 0 Td (Denison )Tj 0.0492 Tc 4.114 0 Td (DM, )Tj ET BT /Suspect <>BDC 0.212 0.212 0.208 rg /T1_0 1 Tf 0.0067 Tc 8.4 0 0 8.4 435.3268 484.09 Tm (Waller )Tj EMC /Suspect <>BDC 0.29 0.29 0.286 rg 0.05 Tc 8.5791 0 0 8.4 463.63 484.09 Tm (JF, )Tj EMC ET BT /T1_0 1 Tf -0.0126 Tc 8.4 0 0 8.4 480.47 484.09 Tm (Assoufi )Tj 0.212 0.212 0.208 rg -0.035 Tc 7.8194 0 0 8.4 512.13 484.09 Tm (B, )Tj 0.29 0.29 0.286 rg 0.0003 Tc 8.4 0 0 8.4 290.84 474.97 Tm (Peacock )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0052 Tc 8.4 0 0 8.4 321.5924 474.97 Tm (A, )Tj EMC ET BT /T1_0 1 Tf 0.0028 Tc 8.4 0 0 8.4 332.9744 474.97 Tm (Sopwith )Tj 0.05 Tc 8.595 0 0 8.4 363.29 474.97 Tm (T. )Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 374.3 474.97 Tm (-)Tj 0.29 0.29 0.286 rg 0.0072 Tc 0.921 0 Td (Direct )Tj 0.0012 Tc 2.861 0 Td (recordings )Tj 0.05 Tc 9.4598 0 0 8.4 444.39 474.97 Tm (of )Tj -0.0088 Tc 8.4 0 0 8.4 455.02 474.97 Tm (the )Tj 0.0148 Tc 1.6 0 Td (temperature )Tj -0.018 Tc 5.251 0 Td (in )Tj 0.212 0.212 0.208 rg -0.0088 Tc -26.394 -1.087 Td (the )Tj 0.29 0.29 0.286 rg 0.0098 Tc 1.6 0 Td (tracheobronchial )Tj -0.0026 Tc 7.314 0 Td (tree )Tj -0.018 Tc 1.823 0 Td (in )Tj 0.0061 Tc 1.15 0 Td (normal )Tj 0.0115 Tc 3.256 0 Td (man. )Tj /T1_3 1 Tf 0 Tc 8 0 0 8 438.17 465.84 Tm (J )Tj /T1_2 1 Tf -0.0102 Tc 0.949 0 Td (Clin )Tj 0.0056 Tc 2.13 0 Td (Invest, )Tj 0.212 0.212 0.208 rg /T1_0 1 Tf -0.0304 Tc 8.4 0 0 8.4 488.35 465.84 Tm (1982, )Tj 0.29 0.29 0.286 rg -0.004 Tc 2.423 0 Td (69)Tj 0.423 0.423 0.416 rg 0 Tc 1.025 0 Td (, )Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_0 1 Tf -0.035 Tc 8.197 0 0 8.4 290.79 457.21 Tm (700)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 302.3 457.21 Tm (-)Tj 0.29 0.29 0.286 rg -0.0234 Tc 0.573 0 Td (705)Tj 0.423 0.423 0.416 rg 0 Tc 1.476 0 Td (. )Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf -0.035 Tc 8.3467 0 0 8.4 290.31 448.09 Tm (9. )Tj 0.0195 Tc 8.4 0 0 8.4 304.76 448.09 Tm (McFadden )Tj 0.05 Tc 8.4073 0 0 8.4 346.03 448.09 Tm (ER )Tj 8.7976 0 0 8.4 360.91 448.09 Tm (Jr)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 367.55 448.09 Tm (, )Tj 0.29 0.29 0.286 rg 0.0091 Tc 0.696 0 Td (Pichurko )Tj -0.006 Tc 4.171 0 Td (BM, )Tj 0.0027 Tc 2.229 0 Td (Bowman )Tj 0.212 0.212 0.208 rg 0.0416 Tc 4.114 0 Td (HF, )Tj 0.008 Tc 2.112 0 Td (Ingenito )Tj -0.035 Tc 8.2744 0 0 8.4 512.11 448.09 Tm (E, )Tj 0.29 0.29 0.286 rg 0.0299 Tc 8.4 0 0 8.4 290.36 439.44 Tm (Bums )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 7.8213 0 0 8.4 313.3 439.44 Tm (S, )Tj EMC ET BT /T1_0 1 Tf -0.0088 Tc 8.4 0 0 8.4 322.52 439.44 Tm (Dowling )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 8.4536 0 0 8.4 353.8 439.44 Tm (N, )Tj EMC /Suspect <>BDC 0.0016 Tc 8.4 0 0 8.4 364.65 439.44 Tm (Solway )Tj EMC ET BT /T1_0 1 Tf -0.0023 Tc 8.4 0 0 8.4 391.6308 439.44 Tm (J. )Tj 0.553 0.557 0.545 rg 0 Tc 0.965 0 Td (-)Tj 0.29 0.29 0.286 rg 0.0103 Tc 0.804 0 Td (Thermal )Tj 0.0179 Tc 3.777 0 Td (mapping )Tj 0.05 Tc 9.4598 0 0 8.4 470.31 439.44 Tm (of )Tj 0.0197 Tc 8.4 0 0 8.4 479.98 439.44 Tm (the )Tj -0.0017 Tc 1.536 0 Td (airways )Tj -0.035 Tc 7.9356 0 0 8.4 290.82 430.33 Tm (in )Tj 0.0027 Tc 8.4 0 0 8.4 299.03 430.33 Tm (humans. )Tj /T1_3 1 Tf 0 Tc 7.4001 0 0 7.4001 330.17 430.33 Tm (J )Tj /T1_2 1 Tf 0.05 Tc 8.0306 0 0 8 336.12 430.33 Tm (Appl )Tj 0.003 Tc 8 0 0 8 353.82 430.33 Tm (Physio/: )Tj 0.212 0.212 0.208 rg 0.0054 Tc 3.72 0 Td (Respirat )Tj 0.29 0.29 0.286 rg 0.0013 Tc 3.72 0 Td (Environ )Tj 0.0214 Tc 3.48 0 Td (Exercise )Tj 0.0062 Tc 3.9 0 Td (Physiol, )Tj 0.212 0.212 0.208 rg /T1_0 1 Tf -0.0304 Tc 8.4 0 0 8.4 501.31 430.33 Tm (1985, )Tj 0.29 0.29 0.286 rg -0.035 Tc 8.3785 0 0 8.4 290.76 421.21 Tm (58, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0008 Tc 8.4 0 0 8.4 303.72 421.21 Tm (564-570. )Tj EMC /Suspect <>BDC -0.035 Tc 7.5202 0 0 8.4 291.58 412.56 Tm (10)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 298.39 412.56 Tm (. )Tj EMC /Suspect <>BDC 0.29 0.29 0.286 rg 0.0095 Tc 1.273 0 Td (Primiano )Tj EMC /Suspect <>BDC 0.212 0.212 0.208 rg 0.048 Tc 4.457 0 Td (FP )Tj EMC /Suspect <>BDC 0.29 0.29 0.286 rg 0.05 Tc 8.7976 0 0 8.4 361.87 412.56 Tm (Jr)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 368.51 412.56 Tm (, )Tj EMC /Suspect <>BDC 0.29 0.29 0.286 rg -0.0123 Tc 0.912 0 Td (Saidel )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.4572 0 0 8.4 402.64 412.56 Tm (GM)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 416.99 412.56 Tm (, )Tj 0.29 0.29 0.286 rg -0.0034 Tc 0.921 0 Td (Tiwari )Tj 0.05 Tc 8.4719 0 0 8.4 453.08 412.56 Tm (K, )Tj 0.0069 Tc 8.4 0 0 8.4 467.97 412.56 Tm (Wood )Tj 0.212 0.212 0.208 rg 0.0406 Tc 3.256 0 Td (RE)Tj 0.423 0.423 0.416 rg 0 Tc 1.356 0 Td (. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 8.4 0 0 8.4 514.464 412.56 Tm (-)Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf 0.0035 Tc 8.4 0 0 8.4 290.8476 403.4376 Tm (Mea)Tj 0.423 0.423 0.416 rg 0 Tc 1.762 0 Td (s)Tj 0.29 0.29 0.286 rg 0.007 Tc 0.414 0 Td (urement )Tj 0.05 Tc 8.9033 0 0 8.4 343.12 403.44 Tm (of )Tj 0.018 Tc 8.4 0 0 8.4 356.15 403.44 Tm (water )Tj 0.0181 Tc 2.97 0 Td (vapor )Tj 0.0012 Tc 3.021 0 Td (dynamics )Tj 0.0169 Tc 4.571 0 Td (during )Tj 0.0153 Tc 3.439 0 Td (breathing )Tj 0.05 Tc 9.4869 0 0 8.4 512.06 403.44 Tm (at )Tj -0.0148 Tc 8.4 0 0 8.4 290.28 394.81 Tm (successive )Tj 0.212 0.212 0.208 rg 0.0083 Tc 4.406 0 Td (locations )Tj 0.29 0.29 0.286 rg -0.0255 Tc 4.112 0 Td (from )Tj 0.0197 Tc 2.351 0 Td (the )Tj 0.0198 Tc 1.6 0 Td (mouth )Tj 0.0253 Tc 3.086 0 Td (to )Tj 0.0092 Tc 1.257 0 Td (third-generation )Tj 0.003 Tc 7.032 0 Td (bronchi. )Tj /T1_2 1 Tf 0.05 Tc 8.0161 0 0 8 291 385.69 Tm (Am )Tj 0.0035 Tc 8 0 0 8 305.82 385.69 Tm (Rev )Tj 0.019 Tc 1.86 0 Td (Respir )Tj -0.0072 Tc 3.063 0 Td (Dis, )Tj 0.212 0.212 0.208 rg /T1_0 1 Tf -0.035 Tc 8.0056 0 0 8.4 362.12 385.69 Tm (1977, )Tj 7.9309 0 0 8.4 382.77 385.69 Tm (115, )Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_0 1 Tf 7.9309 0 0 8.4 399.5676 385.69 Tm (106. )Tj EMC /Suspect <>BDC 0.05 Tc 8.6289 0 0 8.4 291.3 376.56 Tm (II. )Tj EMC ET BT /T1_0 1 Tf 0.0177 Tc 8.4 0 0 8.4 308.12 376.56 Tm (Primiano )Tj 0.048 Tc 4.171 0 Td (FP )Tj 0.05 Tc 8.7976 0 0 8.4 355.15 376.56 Tm (Jr)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 362.27 376.56 Tm (, )Tj 0.29 0.29 0.286 rg 0.0186 Tc 0.525 0 Td (Montague )Tj 0.05 Tc 8.6397 0 0 8.4 404.6 376.56 Tm (FM, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0123 Tc 8.4 0 0 8.4 422.25 376.56 Tm (Saidel )Tj EMC ET BT /T1_0 1 Tf 0.0485 Tc 8.4 0 0 8.4 445.3584 376.56 Tm (GM.)Tj 0.553 0.557 0.545 rg 0 Tc 2.283 0 Td (-)Tj 0.29 0.29 0.286 rg 0.0059 Tc 0.921 0 Td (Measurement )Tj -0.0014 Tc -21.724 -1.027 Td (system )Tj -0.0212 Tc 3.089 0 Td (for )Tj 0.0038 Tc 1.495 0 Td (water )Tj 0.0181 Tc 2.513 0 Td (vapor )Tj 0.0269 Tc 2.621 0 Td (and )Tj 0.009 Tc 1.836 0 Td (temperature )Tj -0.0016 Tc 5.136 0 Td (dynamics. )Tj /T1_3 1 Tf 0 Tc 7.5001 0 0 7.5001 466.49 367.93 Tm (J )Tj /T1_2 1 Tf 0.0326 Tc 8 0 0 8 473.4 367.93 Tm (Appl )Tj ET BT /Suspect <>BDC 0.212 0.212 0.208 rg /T1_2 1 Tf 0.003 Tc 8 0 0 8 491.584 367.93 Tm (Pbysio/: )Tj EMC ET BT 0.29 0.29 0.286 rg /T1_2 1 Tf 0.014 Tc 8 0 0 8 290.944 358.81 Tm (Respirat )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.035 Tc 7.4334 0 0 8 321.66 358.81 Tm (E11viron )Tj EMC ET BT /T1_2 1 Tf 0.0129 Tc 8 0 0 8 350.46 358.81 Tm (Exercise )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.0023 Tc 8 0 0 8 382.14 358.81 Tm (Pbysiol, )Tj EMC ET BT 0.212 0.212 0.208 rg /T1_0 1 Tf -0.035 Tc 8.241 0 0 8.4 411.56 358.81 Tm (1984, )Tj 0.29 0.29 0.286 rg 8.3785 0 0 8.4 431.88 358.81 Tm (56, )Tj 8.1597 0 0 8.4 445.16 358.81 Tm (1679)Tj 0.553 0.557 0.545 rg 0 Tc 8.4 0 0 8.4 460.7 358.81 Tm (-)Tj 0.212 0.212 0.208 rg -0.035 Tc 8.0056 0 0 8.4 466.28 358.81 Tm (1685. )Tj 0.29 0.29 0.286 rg 7.7937 0 0 8.4 291.09 350.16 Tm (12. )Tj 0.006 Tc 8.4 0 0 8.4 308.59 350.16 Tm (Eschenbacher )Tj -0.0125 Tc 5.888 0 Td (WL, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0126 Tc 8.4 0 0 8.4 374.7316 350.16 Tm (Sheppard )Tj EMC ET BT /T1_0 1 Tf 0.016 Tc 8.4 0 0 8.4 409.3984 350.16 Tm (D.)Tj 0.423 0.423 0.416 rg 0 Tc 1.193 0 Td (-)Tj 0.212 0.212 0.208 rg 0.0141 Tc 0.864 0 Td (Respiratory )Tj 0.29 0.29 0.286 rg 0.0184 Tc 5.032 0 Td (heat )Tj -0.018 Tc 1.993 0 Td (loss )Tj -0.035 Tc 7.8068 0 0 8.4 500.1 350.16 Tm (is )Tj 0.0203 Tc 8.4 0 0 8.4 507.35 350.16 Tm (not )Tj 0.0197 Tc -25.83 -1.085 Td (the )Tj -0.0136 Tc 1.817 0 Td (sole )Tj 0.0097 Tc 2.114 0 Td (stimulus )Tj 0.212 0.212 0.208 rg 0.0074 Tc 4.061 0 Td (for )Tj 0.29 0.29 0.286 rg 0.0103 Tc 1.783 0 Td (bronchconstriction )Tj 0.212 0.212 0.208 rg -0.0007 Tc 8.276 0 Td (induced )Tj 0.29 0.29 0.286 rg -0.019 Tc 3.781 0 Td (by )Tj 0.0019 Tc 1.59 0 Td (isocapnic )Tj 0.0088 Tc -23.421 -1.086 Td (hyperpnea )Tj 0 Tc 4.571 0 Td (with )Tj 0.0237 Tc 2.049 0 Td (dry )Tj -0.0116 Tc 1.771 0 Td (air. )Tj /T1_2 1 Tf 0.05 Tc 8.7132 0 0 8 375.01 331.93 Tm (Am )Tj 0.0335 Tc 8 0 0 8 389.82 331.93 Tm (Rev )Tj 0.019 Tc 1.86 0 Td (Respir )Tj 0.0242 Tc 3.063 0 Td (Dis)Tj 0.423 0.423 0.416 rg 0 Tc 1.434 0 Td (, )Tj 0.212 0.212 0.208 rg /T1_0 1 Tf -0.0304 Tc 8.4 0 0 8.4 445.63 331.93 Tm (1985, )Tj -0.035 Tc 7.9309 0 0 8.4 467.25 331.93 Tm (131, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0156 Tc 8.4 0 0 8.4 482.73 331.93 Tm (894-901. )Tj EMC ET BT /T1_0 1 Tf -0.035 Tc 7.7937 0 0 8.4 291.09 323.28 Tm (13. )Tj 0.29 0.29 0.286 rg 0.0373 Tc 8.4 0 0 8.4 308.09 323.28 Tm (Tabka )Tj 0 Tc 2.919 0 Td (Z)Tj 0.423 0.423 0.416 rg 0.674 0 Td (, )Tj 0.29 0.29 0.286 rg -0.035 Tc 8.2246 0 0 8.4 342.68 323.28 Tm (Ben )Tj 0.0161 Tc 8.4 0 0 8.4 357.55 323.28 Tm (Jebria )Tj -0.035 Tc 8.2476 0 0 8.4 380.63 323.28 Tm (A, )Tj 0.029 Tc 8.4 0 0 8.4 390.64 323.28 Tm (Guenard )Tj 0.212 0.212 0.208 rg -0.035 Tc 8.2951 0 0 8.4 423.8 323.28 Tm (H. )Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 434.3 323.28 Tm (-)Tj 0.212 0.212 0.208 rg -0.0167 Tc 0.806 0 Td (Effect )Tj 0.29 0.29 0.286 rg 0.05 Tc 8.9033 0 0 8.4 463.12 323.28 Tm (of )Tj 0.0153 Tc 8.4 0 0 8.4 472.33 323.28 Tm (breathing )Tj 0.0237 Tc 4.104 0 Td (dry )Tj -0.014 Tc -25.763 -1.086 Td (warm )Tj 0.0219 Tc 2.735 0 Td (air )Tj 0.049 Tc 1.543 0 Td (on )Tj 0.0072 Tc 1.608 0 Td (respiratory )Tj 0.0038 Tc 4.914 0 Td (water )Tj -0.018 Tc 2.679 0 Td (loss )Tj 0.0339 Tc 1.942 0 Td (at )Tj -0.0044 Tc 1.323 0 Td (rest )Tj 0.0269 Tc 1.877 0 Td (and )Tj 0.0169 Tc 2 0 Td (during )Tj -0.0155 Tc 3.142 0 Td (exercise)Tj 0.423 0.423 0.416 rg 0 Tc 3.19 0 Td (. )Tj 0.29 0.29 0.286 rg /T1_2 1 Tf 0.007 Tc 8 0 0 8 290.94 305.05 Tm (Respir )Tj 0.0062 Tc 3 0 Td (Physiol, )Tj 0.212 0.212 0.208 rg /T1_0 1 Tf -0.035 Tc 8.241 0 0 8.4 344.84 305.05 Tm (1987, )Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_0 1 Tf 8.3089 0 0 8.4 365.18 305.05 Tm (67, )Tj EMC /Suspect <>BDC -0.0103 Tc 8.4 0 0 8.4 378.91 305.05 Tm (115-125)Tj 0.423 0.423 0.416 rg 0 Tc 3.329 0 Td (. )Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf -0.035 Tc 7.5202 0 0 8.4 291.1 296.41 Tm (14)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 297.91 296.41 Tm (. )Tj 0.29 0.29 0.286 rg 0.017 Tc 1.219 0 Td (Anderson )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.05 Tc 8.5353 0 0 8.4 344 296.41 Tm (SD)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 355.07 296.41 Tm (, )Tj EMC /Suspect <>BDC 0.29 0.29 0.286 rg -0.017 Tc 0.512 0 Td (Schoeffel )Tj EMC ET BT /T1_0 1 Tf 0.0096 Tc 8.4 0 0 8.4 393.08 296.41 Tm (RE, )Tj -0.0197 Tc 1.886 0 Td (Black )Tj 0.0377 Tc 2.513 0 Td (JL)Tj 0.423 0.423 0.416 rg 0 Tc 1.076 0 Td (, )Tj 0.212 0.212 0.208 rg 0.0097 Tc 0.468 0 Td (Daviskas )Tj 0.29 0.29 0.286 rg -0.035 Tc 8.2744 0 0 8.4 477.07 296.41 Tm (E. )Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 486.14 296.41 Tm (-)Tj 0.29 0.29 0.286 rg -0.004 Tc 0.868 0 Td (Airway )Tj 0.0086 Tc -24.237 -1.087 Td (cooling )Tj 0.0362 Tc 3.657 0 Td (as )Tj -0.0088 Tc 1.607 0 Td (the )Tj 0.0097 Tc 1.874 0 Td (stimulus )Tj 0.0253 Tc 4.126 0 Td (to )Tj -0.0079 Tc 1.477 0 Td (exercise-induced )Tj 0.0193 Tc 7.373 0 Td (asthma )Tj 0.423 0.423 0.416 rg 0 Tc 3.598 0 Td (-)Tj 0.29 0.29 0.286 rg 1.202 0 Td (a )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.035 Tc 8.3182 0 0 8.4 509.75 287.28 Tm (re\255)Tj EMC ET BT /T1_0 1 Tf 0.0098 Tc 8.4 0 0 8.4 289.83 278.65 Tm (evaluation)Tj 0.423 0.423 0.416 rg 0 Tc 4.333 0 Td (. )Tj 0.29 0.29 0.286 rg /T1_2 1 Tf -0.006 Tc 8 0 0 8 331.26 278.65 Tm (Eur )Tj /T1_3 1 Tf 0 Tc 1.784 0 Td (J )Tj 0.212 0.212 0.208 rg /T1_2 1 Tf 0.007 Tc 0.976 0 Td (Respir )Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_2 1 Tf -0.0072 Tc 8 0 0 8 377.364 278.65 Tm (Dis, )Tj EMC ET BT /T1_0 1 Tf -0.035 Tc 8.0056 0 0 8.4 394.28 278.65 Tm (1985, )Tj -0.004 Tc 8.4 0 0 8.4 413.66 278.65 Tm (67)Tj 0.423 0.423 0.416 rg 0 Tc 1.025 0 Td (, )Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_0 1 Tf 0.0243 Tc 8.4 0 0 8.4 426.6716 278.65 Tm (20-30. )Tj EMC ET BT /T1_0 1 Tf -0.035 Tc 7.3607 0 0 8.4 291.11 269.53 Tm (15. )Tj 0.212 0.212 0.208 rg 0.0013 Tc 8.4 0 0 8.4 308.6 269.53 Tm (Boucher )Tj 0.29 0.29 0.286 rg 0.0101 Tc 3.657 0 Td (RC, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0203 Tc 8.4 0 0 8.4 355.5308 269.53 Tm (Stutts )Tj EMC ET BT 0.212 0.212 0.208 rg /T1_0 1 Tf 0.0127 Tc 8.4 0 0 8.4 377.7236 269.53 Tm (MJ, )Tj 0.29 0.29 0.286 rg 0.0038 Tc 1.886 0 Td (Bromberg )Tj 0.0151 Tc 4.286 0 Td (PA, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0075 Tc 8.4 0 0 8.4 444.89 269.53 Tm (Gatzy )Tj EMC ET BT /T1_0 1 Tf 0.05 Tc 8.7621 0 0 8.4 467.47 269.53 Tm (JT)Tj 0.423 0.423 0.416 rg 14.6343 0 0 8.4 476.33 269.53 Tm (.-)Tj 0.29 0.29 0.286 rg 0.0076 Tc 8.4 0 0 8.4 487.64 269.53 Tm (Regional )Tj -0.0142 Tc -23.548 -1.086 Td (differences )Tj -0.018 Tc 4.687 0 Td (in )Tj 0.0072 Tc 1.199 0 Td (airway )Tj 0.0093 Tc 3.138 0 Td (surface )Tj -0.006 Tc 3.32 0 Td (liquid )Tj 0.0027 Tc 2.742 0 Td (composition. )Tj /T1_3 1 Tf 0 Tc 7.4001 0 0 7.4001 464.09 260.41 Tm (J )Tj /T1_2 1 Tf 0.0326 Tc 8 0 0 8 471.96 260.41 Tm (Appl )Tj 0.009 Tc 2.453 0 Td (Physiol)Tj 0.423 0.423 0.416 rg 0 Tc 3.035 0 Td (: )Tj 0.29 0.29 0.286 rg 0.0054 Tc -28.175 -1.081 Td (Respirat )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.035 Tc 7.4334 0 0 8 321.18 251.76 Tm (Enviro11 )Tj EMC ET BT /T1_2 1 Tf 0.0284 Tc 8 0 0 8 349.98 251.76 Tm (Exerci)Tj 0.423 0.423 0.416 rg 0 Tc 2.756 0 Td (s)Tj 0.29 0.29 0.286 rg 0.347 0 Td (e )Tj 0.05 Tc 8.0804 0 0 8 381.18 251.76 Tm (Phy)Tj 0.423 0.423 0.416 rg 0 Tc 8 0 0 8 394.59 251.76 Tm (s)Tj 0.29 0.29 0.286 rg -0.009 Tc 0.404 0 Td (iof, )Tj /T1_0 1 Tf -0.035 Tc 8.241 0 0 8.4 411.56 251.76 Tm (1981, )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 8.3785 0 0 8.4 431.88 251.76 Tm (50, )Tj EMC /Suspect <>BDC 0.0059 Tc 8.4 0 0 8.4 444.38 251.76 Tm (613-620. )Tj EMC ET BT 0.212 0.212 0.208 rg /T1_0 1 Tf -0.035 Tc 7.7937 0 0 8.4 290.61 242.65 Tm (16. )Tj 0.29 0.29 0.286 rg 0.0195 Tc 8.4 0 0 8.4 308.12 242.65 Tm (McFadden )Tj -0.0072 Tc 4.97 0 Td (ET )Tj 0.0038 Tc 1.6 0 Td (Jr. )Tj 0 Tc 1.48 0 Td (-)Tj 0.0084 Tc 1.036 0 Td (Respiratory )Tj -0.0007 Tc 5.204 0 Td (heat )Tj 0.05 Tc 8.4599 0 0 8.4 445.83 242.65 Tm (and )Tj 0.018 Tc 8.4 0 0 8.4 462.23 242.65 Tm (water )Tj -0.0108 Tc 2.676 0 Td (exchange: )Tj -0.005 Tc -23.188 -1.087 Td (physiological )Tj 0.0269 Tc 5.818 0 Td (and )Tj -0.0085 Tc 1.943 0 Td (clinical )Tj -0.0006 Tc 3.43 0 Td (implications)Tj 0.423 0.423 0.416 rg 0 Tc 4.96 0 Td (. )Tj 0.29 0.29 0.286 rg /T1_2 1 Tf 8.2 0 0 8.2 431.13 233.52 Tm (J )Tj 0.05 Tc 8.0306 0 0 8 439.32 233.52 Tm (App/ )Tj ET BT /Suspect <>BDC /T1_2 1 Tf -0.0142 Tc 8 0 0 8 459.9 233.52 Tm (Physiol: )Tj EMC ET BT 0.212 0.212 0.208 rg /T1_2 1 Tf 0.014 Tc 8 0 0 8 490.62 233.52 Tm (Respirat )Tj 0.29 0.29 0.286 rg 0.0013 Tc -25.08 -1.079 Td (Environ )Tj 0.0214 Tc 3.6 0 Td (Exercise )Tj 0.0062 Tc 3.96 0 Td (Physiol, )Tj /T1_0 1 Tf -0.035 Tc 8.0056 0 0 8.4 380.84 224.89 Tm (1983, )Tj /T1_2 1 Tf -0.0164 Tc 8 0 0 8 400.72 224.89 Tm (54, )Tj /T1_0 1 Tf -0.035 Tc 7.5803 0 0 8.4 413.67 224.89 Tm (331)Tj 0.553 0.557 0.545 rg 0 Tc 8.4 0 0 8.4 425.18 224.89 Tm (-)Tj 0.29 0.29 0.286 rg -0.0187 Tc 0.571 0 Td (336. )Tj -0.035 Tc 7.7937 0 0 8.4 290.61 215.76 Tm (17. )Tj -0.0211 Tc 8.4 0 0 8.4 308.12 215.76 Tm (Baile )Tj 0.0176 Tc 2.57 0 Td (EM. )Tj 0.0206 Tc 2.344 0 Td (Dahlby )Tj 0.212 0.212 0.208 rg -0.0141 Tc 3.6 0 Td (RW, )Tj 0.29 0.29 0.286 rg -0.022 Tc 2.401 0 Td (Wiggs )Tj 0.0464 Tc 3.027 0 Td (DR, )Tj 0.023 Tc 2.286 0 Td (Pare )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0151 Tc 8.4 0 0 8.4 464.1164 215.76 Tm (PD. )Tj EMC /Suspect <>BDC 0.624 0.624 0.612 rg 0 Tc 2.107 0 Td (-)Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf 0.0007 Tc 8.4 0 0 8.4 490.9964 215.76 Tm (Role )Tj 0.05 Tc 9.4598 0 0 8.4 511.11 215.76 Tm (of )Tj 0.0062 Tc 8.4 0 0 8.4 289.9 206.65 Tm (tracheal )Tj 0.0269 Tc 3.593 0 Td (and )Tj 0.0081 Tc 1.896 0 Td (bronchial )Tj 0.0093 Tc 4.161 0 Td (circulation )Tj -0.035 Tc 7.9356 0 0 8.4 410.82 206.65 Tm (in )Tj 0.0072 Tc 8.4 0 0 8.4 420.47 206.65 Tm (respiratory )Tj 0.0184 Tc 4.8 0 Td (heal )Tj -0.0074 Tc 1.99 0 Td (exchange. )Tj /T1_3 1 Tf 0 Tc 7.5001 0 0 7.5001 514.01 206.65 Tm (J )Tj /T1_2 1 Tf 0.05 Tc 8.0306 0 0 8 290.04 198.01 Tm (App/ )Tj 0.003 Tc 8 0 0 8 308.22 198.01 Tm (Physio/: )Tj 0.014 Tc 3.72 0 Td (Respirat )Tj 0.0013 Tc 3.72 0 Td (Environ )Tj 0.0129 Tc 3.54 0 Td (Exercise )Tj 0.0062 Tc 3.78 0 Td (Physiof, )Tj /T1_0 1 Tf 0.0157 Tc 8.4 0 0 8.4 456.19 198.01 Tm (1985,58,217)Tj 0.423 0.423 0.416 rg 0 Tc 5.108 0 Td (-)Tj 0.29 0.29 0.286 rg -0.035 Tc 8.2652 0 0 8.4 503.95 198.01 Tm (222. )Tj 7.7937 0 0 8.4 290.61 188.89 Tm (18. )Tj 8.3934 0 0 8.4 308.6 188.89 Tm (Baile )Tj -0.0004 Tc 8.4 0 0 8.4 330.19 188.89 Tm (EM)Tj 0.423 0.423 0.416 rg 0 Tc 1.59 0 Td (, )Tj 0.29 0.29 0.286 rg 0.0202 Tc 0.806 0 Td (Osborne )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 8.4 0 0 8.4 384.8068 188.89 Tm (S)Tj 0.423 0.423 0.416 rg 0.517 0 Td (, )Tj EMC /Suspect <>BDC 0.29 0.29 0.286 rg 0.0039 Tc 0.925 0 Td (Pare )Tj EMC /Suspect <>BDC 0.212 0.212 0.208 rg 0.05 Tc 8.4105 0 0 8.4 416.6 188.89 Tm (PD)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 427.99 188.89 Tm (. )Tj EMC /Suspect <>BDC 0.624 0.624 0.612 rg 0.865 0 Td (-)Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf -0.035 Tc 8.3158 0 0 8.4 445.39 188.89 Tm (Effect )Tj 0.05 Tc 9.4598 0 0 8.4 469.35 188.89 Tm (of )Tj 0.0243 Tc 8.4 0 0 8.4 481.36 188.89 Tm (autonomic )Tj 0.0087 Tc -22.789 -1.029 Td (blockade )Tj 0.049 Tc 3.875 0 Td (on )Tj 0.0098 Tc 1.379 0 Td (tracheobronchial )Tj 0.0046 Tc 7.204 0 Td (blood )Tj -0.035 Tc 8.3215 0 0 8.4 416.07 180.25 Tm (ftow, )Tj /T1_3 1 Tf 0 Tc 8 0 0 8 434.33 180.25 Tm (J )Tj 0.212 0.212 0.208 rg /T1_2 1 Tf 0.0326 Tc 0.864 0 Td (Appf )Tj 0.29 0.29 0.286 rg -0.0023 Tc 2.273 0 Td (Physio/, )Tj 0.212 0.212 0.208 rg /T1_0 1 Tf -0.035 Tc 7.8965 0 0 8.4 488.85 180.25 Tm (1987)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 503.87 180.25 Tm (,)Tj 0.29 0.29 0.286 rg -0.004 Tc 0.461 0 Td (62)Tj 0.423 0.423 0.416 rg 0 Tc 1.025 0 Td (, )Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_0 1 Tf -0.035 Tc 8.2534 0 0 8.4 289.81 171.13 Tm (520)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 301.34 171.13 Tm (-)Tj 0.29 0.29 0.286 rg -0.035 Tc 8.2534 0 0 8.4 306.61 171.13 Tm (525)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 318.55 171.13 Tm (. )Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf -0.035 Tc 7.5202 0 0 8.4 290.62 162.49 Tm (19)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 297.91 162.49 Tm (. )Tj 0.29 0.29 0.286 rg 0.007 Tc 1.215 0 Td (Freed )Tj -0.0096 Tc 3.089 0 Td (AN)Tj 0.423 0.423 0.416 rg 0 Tc 1.471 0 Td (, )Tj 0.212 0.212 0.208 rg -0.0051 Tc 1.039 0 Td (Peters )Tj ET BT /Suspect <>BDC 0.29 0.29 0.286 rg /T1_0 1 Tf 0.022 Tc 8.4 0 0 8.4 380.9608 162.49 Tm (SP, )Tj EMC ET BT /T1_0 1 Tf -0.0021 Tc 8.4 0 0 8.4 398.8276 162.49 Tm (Menkes )Tj 0.05 Tc 8.4163 0 0 8.4 431.48 162.49 Tm (HA)Tj 0.423 0.423 0.416 rg 0 Tc 8.4 0 0 8.4 444.31 162.49 Tm (. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 8.4 0 0 8.4 451.576 162.49 Tm (-)Tj EMC ET BT 0.29 0.29 0.286 rg /T1_0 1 Tf -0.0121 Tc 8.4 0 0 8.4 462.706 162.49 Tm (Airflow)Tj 0.423 0.423 0.416 rg 0 Tc 3.075 0 Td (-)Tj 0.29 0.29 0.286 rg -0.0102 Tc 0.346 0 Td (induced )Tj 0.0104 Tc -23.99 -1.086 Td (bronchoconstriction: )Tj 0.0158 Tc 8.798 0 Td (role )Tj 0.05 Tc 9.4598 0 0 8.4 379.59 153.37 Tm (of )Tj 0.0038 Tc 8.4 0 0 8.4 389.19 153.37 Tm (epithelium )Tj 0.05 Tc 8.4599 0 0 8.4 427.59 153.37 Tm (and )Tj 0.0037 Tc 8.4 0 0 8.4 442.95 153.37 Tm (eicosanoid )Tj -0.0292 Tc 4.637 0 Td (med)Tj 0.749 g 0 Tc 1.639 0 Td (.)Tj 0.29 0.29 0.286 rg 0.0007 Tc 0.126 0 Td (iators. )Tj /T1_2 1 Tf 0 Tc 8.2 0 0 8.2 289.53 144.25 Tm (J )Tj 0.05 Tc 8.0306 0 0 8 296.28 144.25 Tm (Appl )Tj 8.0804 0 0 8 314.94 144.25 Tm (Phy)Tj 0.423 0.423 0.416 rg 0 Tc 8 0 0 8 327.87 144.25 Tm (s)Tj 0.29 0.29 0.286 rg 0.0215 Tc 0.464 0 Td (iol)Tj 0.423 0.423 0.416 rg 0 Tc 1.036 0 Td (, )Tj 0.29 0.29 0.286 rg /T1_0 1 Tf -0.035 Tc 8.241 0 0 8.4 345.32 144.25 Tm (1987, )Tj 8.3089 0 0 8.4 365.66 144.25 Tm (62, )Tj 0.0073 Tc 8.4 0 0 8.4 378.6 144.25 Tm (574-581. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0356 Tc 8.4 0 0 8.4 289.8792 129.8524 Tm (RESUME)Tj 0.423 0.423 0.416 rg 0 Tc 4.265 0 Td (: )Tj EMC /Suspect <>BDC 0.29 0.29 0.286 rg /T1_1 1 Tf -0.0056 Tc 7.6 0 0 7.6 332.48 129.85 Tm (La )Tj EMC ET BT /T1_0 1 Tf -0.0011 Tc 8.4 0 0 8.4 346.09 129.85 Tm (pression )Tj 0.0067 Tc 3.886 0 Td (partielle )Tj -0.0197 Tc 3.818 0 Td (de )Tj 0.0173 Tc 1.493 0 Td (vapeur )Tj 0.0286 Tc 3.307 0 Td (d'eau )Tj -0.035 Tc 8.1993 0 0 8.4 473.66 129.85 Tm (\(PH)Tj 0 Tc 5.2 0 0 5.2 486.21 127.93 Tm (2)Tj 0.0445 Tc 8.4 0 0 8.4 489.52 129.85 Tm (o\) )Tj -0.0145 Tc 1.37 0 Td (et )Tj -0.035 Tc 7.2698 0 0 8.4 512.11 129.85 Tm (Ia )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0148 Tc 8.4 0 0 8.4 289.9 121.2 Tm (temperature )Tj EMC ET BT /T1_0 1 Tf 0.0286 Tc 8.4 0 0 8.4 333.496 121.2 Tm (\(T\) )Tj 0.05 Tc 8.8457 0 0 8.4 346.96 121.2 Tm (ont )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0002 Tc 8.4 0 0 8.4 361.35 121.2 Tm (ete )Tj EMC /Suspect <>BDC -0.0079 Tc 1.494 0 Td (mesurees )Tj EMC ET BT /T1_0 1 Tf -0.0054 Tc 8.4 0 0 8.4 406.9536 121.2 Tm (ensemble )Tj 0.0426 Tc 4 0 Td (et )Tj -0.0197 Tc 1.087 0 Td (de )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0309 Tc 8.4 0 0 8.4 460.2348 121.2 Tm (fayon )Tj EMC ET BT /T1_0 1 Tf 0.0176 Tc 8.4 0 0 8.4 481.3608 121.2 Tm (continue )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 12.4 0 0 12.4 513.95 121.2 Tm (a )Tj EMC /Suspect <>BDC 0.0074 Tc 8.4 0 0 8.4 289.37 112.08 Tm (l'extremite )Tj EMC ET BT /T1_0 1 Tf -0.0329 Tc 8.4 0 0 8.4 327.758 112.08 Tm (des )Tj -0.0116 Tc 1.55 0 Td (voies )Tj 0.0014 Tc 2.336 0 Td (aeriennes )Tj 0.0036 Tc 3.998 0 Td (\(soit )Tj -0.0326 Tc 2.061 0 Td (les )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0176 Tc 8.4 0 0 8.4 421.8548 112.08 Tm (levres. )Tj EMC ET BT /T1_0 1 Tf 0.0036 Tc 8.4 0 0 8.4 445.3244 112.08 Tm (soit )Tj 0.212 0.212 0.208 rg -0.035 Tc 7.9707 0 0 8.4 460.25 112.08 Tm (les )Tj 0.29 0.29 0.286 rg -0.0045 Tc 8.4 0 0 8.4 470.87 112.08 Tm (narines\), )Tj -0.0116 Tc 3.706 0 Td (ainsi )Tj -0.0021 Tc -25.314 -1.086 Td (que )Tj 0.0209 Tc 2.114 0 Td (dans )Tj 0.0198 Tc 2.548 0 Td (!'oropharynx, )Tj 0.0065 Tc 6.252 0 Td (chez )Tj -0.0329 Tc 2.457 0 Td (des )Tj -0.0042 Tc 1.938 0 Td (sujets )Tj 0.0077 Tc 2.927 0 Td (humains )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0 Tc 12.4 0 0 12.4 476.51 102.96 Tm (a )Tj EMC ET BT /T1_0 1 Tf 0.0191 Tc 8.4 0 0 8.4 486.25 102.96 Tm (poumons )Tj 0.0084 Tc -23.374 -1.029 Td (normaux )Tj 0.05 Tc 8.8578 0 0 8.4 323.92 94.32 Tm (ou )Tj 0.0224 Tc 8.4 0 0 8.4 336.88 94.32 Tm (atteints )Tj 0.0374 Tc 3.486 0 Td (de )Tj 0.212 0.212 0.208 rg -0.0181 Tc 1.427 0 Td (fibrose )Tj 0.29 0.29 0.286 rg -0.0115 Tc 3.208 0 Td (kystique. )Tj ET BT /Suspect <>BDC /T1_0 1 Tf 0.0002 Tc 8.4 0 0 8.4 439.1164 94.32 Tm (On )Tj EMC ET BT 0.212 0.212 0.208 rg /T1_0 1 Tf 0.0116 Tc 8.4 0 0 8.4 454.0684 94.32 Tm (n'a )Tj 0.29 0.29 0.286 rg 0.0156 Tc 1.656 0 Td (trouve )Tj 0.0193 Tc 3.021 0 Td (aucune )Tj ET BT /Suspect <>BDC /T1_0 1 Tf -0.0045 Tc 8.4 0 0 8.4 289.3528 85.1976 Tm (diflerence )Tj EMC ET BT /T1_0 1 Tf 0.0304 Tc 8.4 0 0 8.4 323.9104 85.1976 Tm (apparente )Tj 0.0209 Tc 4.343 0 Td (dans )Tj 0.212 0.212 0.208 rg -0.035 Tc 7.2698 0 0 8.4 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0 8.5 215.423 720.73 Tm (\(95%\) )Tj 0.032 Tc 2.836 0 Td (pour )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.0196 Tc 8.5 0 0 8.5 258.161 720.73 Tm (ceux )Tj EMC ET BT /T1_1 1 Tf -0.0122 Tc 8.5 0 0 8.5 276.402 720.73 Tm (qui )Tj 0.0079 Tc -25.46 -1.073 Td (respirent )Tj 0.0441 Tc 4.012 0 Td (par )Tj 0.137 0.141 0.133 rg -0.0271 Tc 1.741 0 Td (le )Tj 0.22 0.223 0.212 rg -0.0137 Tc 1.136 0 Td (nez )Tj -0.0105 Tc 1.799 0 Td (que )Tj 0.032 Tc 1.874 0 Td (pour )Tj -0.0196 Tc 2.305 0 Td (ceux )Tj -0.0122 Tc 2.315 0 Td (qui )Tj 0.0008 Tc 1.759 0 Td (respirent )Tj 0.05 Tc 9.1296 0 0 8.5 236.65 711.61 Tm (par )Tj ET BT /Suspect <>BDC 0.137 0.141 0.133 rg /T1_1 1 Tf -0.0272 Tc 8.5 0 0 8.5 252.42 711.61 Tm (Ia )Tj EMC ET BT 0.22 0.223 0.212 rg /T1_1 1 Tf 0.012 Tc 8.5 0 0 8.5 262.569 711.61 Tm (bouche )Tj -0.0039 Tc -23.844 -1.016 Td (\(75%\). )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 8.1734 0 0 8.5 88.65 702.97 Tm (Si )Tj EMC ET BT 0.137 0.141 0.133 rg /T1_1 1 Tf 0.0262 Tc 8.5 0 0 8.5 100.52 702.97 Tm (!'on )Tj ET BT /Suspect <>BDC 0.22 0.223 0.212 rg /T1_1 1 Tf -0.0106 Tc 8.5 0 0 8.5 119.509 702.97 Tm (respire )Tj EMC ET BT /T1_1 1 Tf 0.026 Tc 8.5 0 0 8.5 146.8025 702.97 Tm (de )Tj 0.0216 Tc 1.582 0 Td (l'air )Tj 0.0156 Tc 2.201 0 Td (chaud )Tj 0.027 Tc 3.104 0 Td (\(48\2612"C\), )Tj -0.0272 Tc 4.861 0 Td (Ia )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 7.8198 0 0 8.5 258.21 702.97 Tm (PH)Tj 0 Tc 5.5001 0 0 5.5001 268.13 701.05 Tm (1)Tj 8.5 0 0 8.5 271.12 702.97 Tm (o )Tj EMC ET BT /T1_1 1 Tf -0.0226 Tc 8.5 0 0 8.5 281.1925 702.97 Tm (et )Tj 0.0184 Tc -26.031 -1.073 Td (l'humid)Tj 0.322 0.322 0.318 rg 0 Tc 3.106 0 Td (i)Tj 0.22 0.223 0.212 rg -0.035 Tc 8.4377 0 0 8.5 88.78 693.85 Tm (te )Tj -0.0161 Tc 8.5 0 0 8.5 97.91 693.85 Tm (relative )Tj 0.026 Tc 3.154 0 Td (de )Tj 0.0216 Tc 1.3 0 Td (l'air )Tj 0.0013 Tc 1.864 0 Td (inspire )Tj 0.0281 Tc 2.991 0 Td (au )Tj -0.0124 Tc 1.365 0 Td (niveau )Tj 0.05 Tc 8.7609 0 0 8.5 213.04 693.85 Tm (du )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.0014 Tc 8.5 0 0 8.5 225.13 693.85 Tm (pharynx )Tj EMC /Suspect <>BDC 0.0366 Tc 3.599 0 Td (sont )Tj EMC ET BT /T1_1 1 Tf 0.0124 Tc 8.5 0 0 8.5 273.1295 693.85 Tm (plus )Tj -0.0139 Tc -25.085 -1.016 Td (faibles )Tj 0.0323 Tc 2.994 0 Td (dans )Tj -0.0271 Tc 2.316 0 Td (le )Tj 0.0012 Tc 1.129 0 Td (groupe )Tj -0.0305 Tc 3.218 0 Td (de )Tj -0.0191 Tc 1.354 0 Td (fibroses )Tj -0.0344 Tc 3.504 0 Td (lcystiques )Tj 0.0177 Tc 4.121 0 Td (que )Tj 0.0135 Tc 1.864 0 Td (dans )Tj -0.0271 Tc 2.316 0 Td (le )Tj 0.0237 Tc 1.073 0 Td (groupe )Tj 0.0049 Tc -23.88 -1.073 Td (normal. )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.035 Tc 8.6219 0 0 9.3 89.24 676.09 Tm (De )Tj EMC ET BT /T1_1 1 Tf -0.0109 Tc 8.5 0 0 8.5 101.29 676.09 Tm (plus, )Tj 0.137 0.141 0.133 rg -0.0271 Tc 2.136 0 Td (le )Tj 0.22 0.223 0.212 rg 0.0124 Tc 0.904 0 Td (groupe )Tj 0.026 Tc 3.048 0 Td (de )Tj -0.0191 Tc 1.185 0 Td (fibroses )Tj -0.0129 Tc 3.34 0 Td (kystiques )Tj 0 Tc 3.945 0 Td (a )Tj 0.0129 Tc 0.745 0 Td (une )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.0146 Tc 8.5 0 0 8.5 245.7475 676.09 Tm (temperature )Tj EMC ET BT 0.137 0.141 0.133 rg /T1_1 1 Tf -0.0121 Tc 8.5 0 0 8.5 310.968 729.8525 Tm (des )Tj 0.22 0.223 0.212 rg -0.0041 Tc 1.633 0 Td (surfaces )Tj -0.0121 Tc 3.506 0 Td (des )Tj -0.0176 Tc 1.645 0 Td (voies )Tj -0.0041 Tc 2.307 0 Td (aeriennes )Tj 0 Tc 4.021 0 Td (p)Tj 0.322 0.322 0.318 rg 0.499 0 Td (l)Tj 0.22 0.223 0.212 rg -0.035 Tc 8.4369 0 0 8.5 429.6 729.85 Tm (us )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.0315 Tc 8.5 0 0 8.5 439.59 729.85 Tm (elevee )Tj EMC /Suspect <>BDC 0 Tc 12.8 0 0 12.8 462.59 729.85 Tm (a )Tj EMC /Suspect <>BDC 0.008 Tc 8.5 0 0 8.5 469.85 729.85 Tm (l'extremite )Tj EMC ET BT /T1_1 1 Tf -0.0121 Tc 8.5 0 0 8.5 508.7205 729.85 Tm (des )Tj -0.0176 Tc 1.645 0 Td (voies )Tj -0.0041 Tc -24.912 -1.073 Td (aeriennes )Tj 0.0281 Tc 4.235 0 Td (au )Tj 0.0002 Tc 1.469 0 Td (cours )Tj -0.0305 Tc 2.654 0 Td (de )Tj 0.0044 Tc 1.388 0 Td (!'inspiration. )Tj -0.0323 Tc 5.613 0 Td (Ces )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.0204 Tc 8.5 0 0 8.5 457.831 720.7295 Tm (donnees )Tj EMC ET BT /T1_1 1 Tf 0.0046 Tc 8.5 0 0 8.5 490.4285 720.7295 Tm (suggerent )Tj 0.0177 Tc 4.353 0 Td (que )Tj 0.0016 Tc -25.411 -1.073 Td (lorsque )Tj -0.0271 Tc 3.558 0 Td (le )Tj 0.011 Tc 1.361 0 Td (taux )Tj 0.017 Tc 2.365 0 Td (d'evaporation )Tj -0.0082 Tc 6.267 0 Td (est )Tj -0.0044 Tc 1.747 0 Td (suffisamment )Tj ET BT /Suspect <>BDC /T1_1 1 Tf -0.0268 Tc 8.5 0 0 8.5 492.8595 711.609 Tm (eleve, )Tj EMC /Suspect <>BDC 0.0177 Tc 2.882 0 Td (l'etape )Tj EMC ET BT /T1_1 1 Tf -0.0092 Tc 8.5 0 0 8.5 311.4355 702.973 Tm (limitative )Tj 0.0254 Tc 4.301 0 Td (pourrait )Tj ET BT /Suspect <>BDC /T1_1 1 Tf 0.0162 Tc 8.5 0 0 8.5 380.532 702.973 Tm (etrc )Tj EMC ET BT /T1_1 1 Tf -0.0271 Tc 8.5 0 0 8.5 398.314 702.973 Tm (le )Tj 0.0151 Tc 1.248 0 Td (transport )Tj 0.0222 Tc 4.285 0 Td (d'eau )Tj 0.05 Tc 8.7989 0 0 8.5 468.87 702.97 Tm (au )Tj -0.0008 Tc 8.5 0 0 8.5 482.86 702.97 Tm (travers )Tj 0.05 Tc 8.7609 0 0 8.5 510.64 702.97 Tm (du )Tj -0.0056 Tc 8.5 0 0 8.5 524.62 702.97 Tm (tissu )Tj 0.0019 Tc -25.129 -1.073 Td (muqueux )Tj -0.0001 Tc 4.284 0 Td (etfou )Tj 0.137 0.141 0.133 rg -0.0121 Tc 2.655 0 Td (des )Tj ET BT /Suspect <>BDC 0.22 0.223 0.212 rg /T1_1 1 Tf -0.0018 Tc 8.5 0 0 8.5 385.322 693.8495 Tm (secretions)Tj 0.322 0.322 0.318 rg 0 Tc 4.002 0 Td (. )Tj EMC /Suspect <>BDC 0.22 0.223 0.212 rg -0.0145 Tc 0.801 0 Td (Ce )Tj EMC ET BT /T1_1 1 Tf 0.011 Tc 8.5 0 0 8.5 440.1385 693.8495 Tm (taux )Tj 0.026 Tc 2.308 0 Td (de )Tj 0.0159 Tc 1.526 0 Td (limitation )Tj 0.0201 Tc 4.572 0 Td (est )Tj -0.0064 Tc 1.706 0 Td (plus )Tj -0.0011 Tc -25.311 -1.016 Td (evident, )Tj 0.0287 Tc 3.453 0 Td (tout )Tj 0.0281 Tc 1.855 0 Td (au )Tj 0.0115 Tc 1.194 0 Td (moins )Tj 0.0323 Tc 2.647 0 Td (dans )Tj -0.035 Tc 8.4396 0 0 8.5 406.97 685.21 Tm (les )Tj -0.0176 Tc 8.5 0 0 8.5 417.58 685.21 Tm (voies )Tj 0.0029 Tc 2.251 0 Td (aeriennes )Tj ET BT /Suspect <>BDC 0.322 0.322 0.318 rg /T1_1 1 Tf 0 Tc 8.5 0 0 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