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[(.)-495.5(C)0(h)16.5(e)0(s)13.9(t)-498.2(ra)19.2(di)18.9(og)15.5(ra)19.2(ph)15.5(y)-501.5(o)0(n)-490.9(a)0(d)20.8(m)0(i)15.7(s)0(s)18.9(i)0(o)13.2(n)-495.8(sh)14.4(ow)17.3(ed)]TJ -5.1955 -1.0698 TD [(al)12.8(mo)18.1(st)-312.4("n)18.3(or)14(ma)17.7(l")-314.2(lu)13.2(ng)21.2(.)]TJ 1.0015 -1.0471 TD [(T)69.1(w)0(o)-443.6(d)0(a)20.8(y)0(s)-440.9(a)0(f)19.2(t)0(e)18.4(r)-451.9(ad)20.8(mi)15.7(ss)13.2(i)13.9(o)0(n)15.5(,)-449.9(th)18.9(e)-450.7(p)0(a)20.8(t)0(i)16.5(e)0(n)20.8(t)-452.7(co)20.8(mp)12.4(la)18.4(in)18.8(ed)-440.1(of)]TJ -1.0015 -1.0698 TD [(pr)13.9(og)21.2(re)13.5(ss)18.9(iv)18.9(e)-490.6(e)0(x)15.1(e)0(r)19.2(t)0(i)16.5(o)0(n)15.5(a)0(l)-482.3(d)0(y)21.2(s)0(p)14.3(n)0(o)21.2(e)0(a)14.7(.)-489.8(Ro)16.5(om)18.1(-a)19.2(ir)-483.5(bl)13.2(oo)21.2(d)-490.2(g)0(a)15.1(s)0(e)19.6(s)]TJ 0 -1.0641 TD [(re)13.5(ve)20.8(al)12.8(ed)-508.4(ar)19.2(te)12.8(ri)17.3(al)-510.8(ox)21.2(yg)15.5(en)-508.4(te)12.8(ns)20(io)18.9(n)-518.6(\()]TJ /F5 1 Tf 14.0784 0 TD (P)Tj /F4 1 Tf 7.97 0 0 7.97 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Mom{^5>Ɋxomےj3EZ҂&dbtX xwP KCXcJ+>w0$؀~$|{{> stream BT /F4 1 Tf 9.963 0 0 9.963 58.28 320.372 Tm 0 g /GS2 gs 0 Tc [(Lung)-445.3(tissue)-444.6(obtai)-9(ned)-440.9(by)-439.7(trans)-9.4(bronchial)-446.5(biops)-7.4(y)-438.9(show)-8.2(ed)]TJ 0 -1.0528 TD [(well-co)-10.7(nserve)-8.2(d)-404.8(alveolar)-412(structure)-11.1(,)-404.4(with)-404.4(alveol)-10.1(i)-401.5(line)-8.2(d)-404.8(b)0(y)]TJ 0 -1.0471 TD [(prom)-7.8(inent)-441.5(type)-438.3(II)-442.9(alveolar)-446.1(pneumo)-8.1(cytes,)-441.1(and)-440.9(the)-437.6(pres-)]TJ 0 -1.0528 TD [(ence)-311.6(of)-310.4(a)-308.5(large)-304.5(numbe)-7.4(r)-309.7(o)0(f)-310.4(macr)-8.6(ophages)-314.6(withi)-9.2(n)-308.1(the)-312.4(small)]TJ 0 -1.0471 TD [(airspa)-10.6(ces)-214.8(\(not)-217.6(shown\).)-222.2(Giant)-217.8(cell)-8.6(s)-212.5(were)-219.9(not)-215.2(detected)-223(in)-214.5(the)]TJ 0 -1.0527 TD [(affected)-263.7(area.)-273.7(Sputum)-271.1(culture)-274.3(was)-263.9(neg)-8.4(ative)-265.5(for)-272.9(other)-270(bac-)]TJ 0 -1.0471 TD 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[(ce)14.7(ll)16.5(s)-212.5(w)12.4(er)13.5(e)-211.7(d)0(i)18.9(v)0(i)18.9(d)0(e)15.1(d)-211.3(i)13.9(n)0(t)13.2(o)-211.3(ad)20.8(he)15.1(re)19.2(nt)-203.1(\(m)16.5(ai)18.5(nl)18.9(y)-211.3(m)0(a)12(c)0(r)19.2(o)0(p)15.5(h)0(a)20.8(g)0(e)15.1(s)0(\))-197.8(a)0(n)15.1(d)]TJ T* [(no)15.5(na)15.1(dh)21.2(er)19.2(en)15.1(t)-555.1(\()0(l)17.3(y)0(m)18.1(p)0(h)15.5(o)0(c)20.8(y)0(t)18.9(e)0(-)13.5(r)0(i)17.3(c)0(h)20.8(\))-554.3(ce)14.7(ll)-546.9(fr)18(ac)14.7(ti)22.2(on)15.5(s)-553.9([)0(8)19.6(])0(.)-566.1(T)57.7(otal)]TJ T* [(RNA)-140.1(was)-218.4(extra)-8.6(cted)-216.8(from)-219.9(the)-215.6(cult)-8.2(ure)-214.8(supern)-7.8(atant)-9.4(,)-210.9(adheren)-8.2(t)]TJ T* [(cell)-8.6(s,)-434.8(non)-8(adheren)-8.2(t)-435.6(cells,)-443.4(as)-441.3(well)-438.9(as)-441.3(the)-437.6(pati)-8.2(ent)]TJ /F8 1 Tf 19.3365 0 TD (')Tj /F4 1 Tf 0.2219 0 TD [(s)-440.1(serum)]TJ -19.5584 -1.0641 TD [(using)-326.1(the)-323.7(guanid)-7.4(iniu)-7.8(m)-316.9(iso-)-8.2(thiocyan)-11.7(ate-CsCl)]TJ 7.472 0 0 6.641 485.972 685.247 Tm (2)Tj 9.963 0 0 9.963 492.945 686.891 Tm [(ultracent)-11.1(ri-)]TJ -18.4317 -1.0584 TD [(fugat)-8.2(ion)-539.6(met)-8.2(hod)-537.2(or)-538(the)-540(acid)-541.2(guan)-9.1(idinium)-544.8(thiocyanat)-10.3(e)]TJ 0 -1.0641 TD [(phe)-8.4(nol-chloro)-10.3(form)-396.3(extra)-8.6(ction)-401.6(method)-397.5([9,)-396.1(1)-6.5(0].)-396.2(Resultant)]TJ T* [(RNA)-310.8(was)-383.4(diss)-7.8(olved)-387.9(in)-385.2(10)]TJ /F11 1 Tf 11.0169 0 TD (m)Tj /F4 1 Tf 0.5747 0 TD [(L)-386.2(o)0(f)-384.4(ribon)-7.8(uclease)-391.8(\(RNase\)-)]TJ -11.5916 -1.0641 TD [(free)-405.4(distilled)-401.6(wat)-9(er)53.4(.)-398.7(The)-393.8(init)-10.2(ial)-394.4(trans)-9.4(cription)-402.2(of)-395.8(RNA)-401.8(to)]TJ T* [(compl)-9.7(ementary)-355.9(deoxyribon)-12(ucleic)-346.3(acid)-353.4(\(cDNA\))-350(was)-349.3(per-)]TJ T* [(form)-9.4(ed)-212.5(by)-212.1(using)-212.2(Molo)-7.4(ney)-213.3(murine)-217(leukae)-8.2(mia)-213.1(virus)-213.8(revers)-9.8(e)]TJ 0 -1.0584 TD [(trans)-9.4(criptase)-447.3(with)-444.2(random)-442.2(he)-7.6(xamer)-441.8(primers)-448.1([1)31(1].)-441.7(T)57.7(wo-)]TJ 0 -1.0641 TD [(step)-342.8(amplifi)-11.9(cation)-340.2(\(semi-ne)-11.1(sted)-337.1(PCR\))-343.3(was)-337.9(carri)-10.2(ed)-337.7(out)-334.7(to)]TJ T* [(detect)-329.2(the)-323.7(mat)-8.2(rix)-324.9(gene)-322.5(of)-327.5(measles)-327.4(viral)-329.2(genom)-7.4(e)-319.8(with)-324.7(the)]TJ T* [(prim)-10.2(er)-544.1(pairs)-544.3(as)-543.7(descri)-10.5(bed)-543.3(by)-542.1(S)]TJ 6.974 0 0 6.974 443.168 580.989 Tm 0.0001 Tc (HIMIZU)Tj /F5 1 Tf 9.963 0 0 9.963 473.499 580.989 Tm 0 Tc [(e)-6.9(t)-538.1(al.)]TJ /F4 1 Tf 2.8168 0 TD [([12];)-550(5)]TJ /F8 1 Tf 2.9648 0 TD (')Tj /F4 1 Tf 0.2162 0 TD (-)Tj -22.4777 -1.0641 TD [(GTG)-8.6(TTGT)-8(TT)75.6(A)97.7(T)74.8(A)103.4(TGA)-8.6(GCA)98.9(TCAC)-9.2(-3)]TJ /F8 1 Tf 15.0231 0 TD (')Tj /F4 1 Tf 0.8251 0 TD [(\(MV03\))-616.8(and)-611.6(5)]TJ /F8 1 Tf 6.4132 0 TD (')Tj /F4 1 Tf 0.2162 0 TD (-)Tj -22.4777 -1.0641 TD [(AA)98.7(TCGA)94.1(TT)69.9(AAGGTC)-12.1(TTCA)99.6(TTGA)100.4(T)80.5(-)0(3)]TJ /F8 1 Tf 15.6262 0 TD (')Tj /F4 1 Tf 0.5008 0 TD [(\(MV05\))-286.8(as)-282(outer)]TJ -16.127 -1.0584 TD [(prim)-10.2(ers,)-392.8(and)-395.3(for)-392.4(the)-397.7(second)-393.5(semi)-10.2(-nested)-398.3(PCR,)-398.3(an)-388.9(inner)]TJ 0 -1.0641 TD [(anti)-8.2(sense)-416.7(primer)-417.7(MV04)-413(\(5)]TJ /F8 1 Tf 10.9259 0 TD (')Tj /F4 1 Tf 0.2162 0 TD [(-C)-7.8(A)103.4(TTTTG)-7.2(CAA)98.9(T)69.1(A)0(A)104.4(TCG)-9.4(G-)]TJ -11.1421 -1.0641 TD [(CAG)-9.2(AGT)76.8(-3)]TJ /F8 1 Tf 4.8996 0 TD (')Tj /F4 1 Tf 0.2162 0 TD [(\))-406.4(was)-406.2(used)-408.7(instead)-410.4(of)-401.5(MV)-7.4(05)-405.6([13].)-405(The)-405.2(re-)]TJ -5.1158 -1.0641 TD [(acti)-8.6(on)-422.6(con)-8.4(ditions)-429.1(were)-430.5(first)-428.4(94)]TJ /F8 1 Tf 12.7582 0 TD (8)Tj /F4 1 Tf 0.387 0 TD [(C)-426.6(for)-426.6(3)-427.6(min,)-429.3(and)-429.5(them)]TJ -13.1452 -1.0641 TD (94)Tj /F8 1 Tf 1.0015 0 TD (8)Tj /F4 1 Tf 0.387 0 TD [(C)-409.5(for)-409.5(1)-404.8(min,)-412.2(60)]TJ /F8 1 Tf 6.7376 0 TD (8)Tj /F4 1 Tf 0.387 0 TD [(C)-403.8(for)-409.5(1)-404.8(min)-7.8(,)-404.4(and)-406.7(72)]TJ /F8 1 Tf 8.5757 0 TD (8)Tj /F4 1 Tf 0.387 0 TD [(C)-403.8(for)-409.5(1)-410.5(min,)]TJ -17.4757 -1.0641 TD [(whi)-8.6(ch)-246.6(were)-248.4(repeat)-9.8(ed)-246.6(for)-250.2(40)-246.2(cycles)-9.4(.)-245.1(A)-249.4(single)-249.9(PCR)-249.9(product)]TJ ET /GS3 gs q 223.389 0 0 197.8374 61.3238 567.1062 cm /Im1 Do Q q 223.389 0 0 157.9652 61.3238 394.1858 cm /Im2 Do Q BT /F15 1 Tf 9.7 0 0 9.7 61.324 769.818 Tm 0 0 0 1 k /GS4 gs (a\))Tj 0.1 -22.0516 TD (b\))Tj /F4 1 Tf 7.97 0 0 7.97 58.28 382.564 Tm 0 g /GS2 gs [(Fig.)-327.1(1.)-331.2(\261)-645.2(Radiological)-306.1(examination)11.6(s)-319.2(o)0(f)-309(the)-315.2(lung.)-313(a\))-307.9(a)-317(chest)-311.1(radiograph)]TJ 0 -1.067 TD [(on)-422.6(day)-419.5(4)-424.7(demonst)11.9(rating)-425.2(diff)12.8(use)-420.7(reticulonod)10.7(ular)-427.1(infiltrates)-415.1(of)-422.8(bilateral)]TJ 0 -1.0599 TD [(lungs.)-290.8(b\))-294.7(chest)-296.9(high)-292.7(resolution)-292.4(computed)-289.7(tomogram)-291.2(on)-294.6(day)-291.4(4)-296.7(revealing)]TJ T* [(diff)12.8(use)-292.6(ground-glass)-291.9(opacities,)-291.2(multiple)-290.8(centrilobular)-292.5(nodules,)-285.5(and)-298.6(con-)]TJ 0 -1.067 TD [(solidations)-322.1(predominant)-328.6(in)-325.4(the)-336.5(right)-328.8(upper)-330.1(lobe.)]TJ /F15 1 Tf 10 0 0 10 455.259 389.823 Tm 0 0 0 1 k /GS4 gs 1.844 Tc (4567)Tj -7.15 7.9 TD 0 Tc (Ed)Tj 3.55 0.45 TD (Measles patient)Tj -1.3 -1.45 TD [(AM)-664.9(L)30(y)0(m)]TJ 3.7495 0.0067 TD (Sup)Tj 1.9288 -0.0067 TD (Serum)Tj 3.8217 1.45 TD (N)Tj 2.35 -0.35 TD (C)Tj -2.6 -1.1 TD (AM)Tj ET 0 0 0 1 K 0 J 0 j 0.5 w 3.864 M []0 d /GS3 gs 1 i 405.259 470.323 m 485.259 470.323 l 496.259 470.323 m 511.259 470.323 l S BT 10 0 0 10 417.275 367.323 Tm /GS4 gs (Measles patient)Tj 0.1484 -1.4 TD (AM)Tj 4.5949 -0.05 TD -0.03 Tc [(Ly)-30(m)]TJ ET /GS3 gs 409.259 364.323 m 481.259 364.323 l S BT 10 0 0 10 512.315 367.323 Tm /GS4 gs 0 Tc (N)Tj -0.25 -1.45 TD (AM)Tj ET /GS3 gs 507.315 364.323 m 522.315 364.323 l S BT 10 0 0 10 311.76 432.024 Tm /GS4 gs (415 bp)Tj ET 1.5 w /GS3 gs 341.26 424.323 m 320.26 424.323 l S 340.718 424.323 m 340.718 427.573 l 348.843 424.323 l 340.718 421.073 l 340.718 424.323 l f* BT 10 0 0 10 312.26 314.524 Tm /GS4 gs (555 bp)Tj ET /GS3 gs 341.76 306.824 m 320.76 306.824 l S 341.218 306.824 m 341.218 310.074 l 349.343 306.824 l 341.218 303.574 l 341.218 306.824 l f* BT 10 0 0 10 362.259 389.823 Tm /GS4 gs (M)Tj 2.3 -0.0067 TD (1)Tj 2.3 0.0067 TD 1.944 Tc (23)Tj -3.5 -12.85 TD 0 Tc (M)Tj 4.75 -0.0067 TD (1)Tj 4.85 0.0067 TD 4.094 Tc (23)Tj ET /GS3 gs q 187.9991 0 0 48.1743 351.1025 406.1483 cm /Im3 Do Q q 187.9991 0 0 74.0942 351.6923 273.229 cm /Im4 Do Q BT /F4 1 Tf 7.97 0 0 7.97 309.26 243.723 Tm 0 g /GS2 gs 0 Tc [(Fig.)-327.1(2.)-331.2(\261)-332.2(Detection)-307.8(of)-316.1(the)-315.2(measles)-307.4(virus)-313.4(genome)-305.7(in)-318.3(lung)-307(cells)-313.5(from)-312.4(the)]TJ 0 -1.0599 TD [(individual)-250.7(with)-247.8(measles)-250.5(pneumonia)-252(by)-251.9(reverse)-247(transcription-p)8.1(olymerase)]TJ T* [(chain)-231.7(reaction)-226.9(\(R)56.2(T)84.7(-PCR\))-231.8(amplificatio)8.8(n.)-231.6(a\))-229.7(first-round)-225.4(PCR)-228.5(amplification)]TJ 0 -1.067 TD [(showing)-283(the)-293.8(presence)-286.4(of)-287.6(measles)-286.1(virus)-292(in)-289.8(lung)-292.7(cells)-285.1(recovered)-290.4(by)-287.5(bron-)]TJ 0 -1.0599 TD [(choalveolar)-262.3(lavage)-271.3(\(BAL\))-270(but)-273.5(not)-266.4(in)-275.6(lavage)-264.1(supernatant)-264.5(or)-273.4(serum)-267.6(of)-273.4(the)]TJ 0 -1.067 TD [(patient.)-309.5(M,)-316(molecu)12(lar)-315.3(marker)-313.2(\()]TJ /F10 1 Tf 12.3626 0 TD (W)Tj /F4 1 Tf 0.7184 0 TD (X174/)Tj /F5 1 Tf 2.4825 0 TD (Hae)Tj /F4 1 Tf 1.6502 0 TD [(III\);)-319.8(lane)-312(1,)-309.8(ribonucleic)-308.4(acid)]TJ -17.2138 -1.0599 TD [(\(RNA\))-234.3(extracted)-238(from)-234.1(Edmonston)]TJ /F8 1 Tf 13.4936 0 TD (')Tj /F4 1 Tf 0.2205 0 TD [(s)-241(measles)-229.2(virus)-242.2(strain)-234.4(\(Ed\))-236.5(as)-237.8(positive)]TJ -13.7141 -1.0599 TD [(control)-579.6([20];)-582.6(lanes)-581.4(2\2615,)-575.9(alveolar)-582.6(macropha)12.3(ges)-584.3(\(AM\),)-575.8(lymphocytes)]TJ 0 -1.0029 TD [(\(L)51.1(ym\),)-547.9(supernata)11.1(nt)-553(\(Sup\))-549.6(recovered)-546.4(by)-550.6(BAL,)-543.1(and)-547.5(serum)-552.1(from)-547.1(the)]TJ 0 -0.9958 TD [(measles)-278.9(patient,)-273.9(respectively;)-278.3(lane)-276.5(6,)-281.4(AM)-281.9(from)-276.8(a)-281.4(healthy)-272.6(volunteer)-275.6(\(N\);)]TJ 0 -1.0029 TD [(lane)-319.2(7,)-316.9(negative)-319.2(control)-316.4(with)-319(no)-315.9(complementar)9.6(y)-318(deoxyribonucle)13.3(ic)-324.4(acid)]TJ T* [(\(cDNA\))-378.3(\(C\).)-381.8(b\))-380.1(R)54.3(T)84.7(-PCR)-376(amplification)-373.2(of)-387.2(glyceralde)13(hyde-3-phosph)12.6(ate)]TJ 0 -0.9958 TD [(dehydroge)13.7(nase)-289.5(\(GAPDH)11.8(\))-289.7(cDNA)-282.6(as)-287.6(control:)-281.1(M,)-280.5(molecular)-282(marker)-284.8(as)-287.6(in)]TJ 0 -1.003 TD [(a\);)-286.9(lanes)-289.8(1)-289.6(and)-284.3(2,)-288.5(AM,)-280.9(and)-291.4(L)56.3(y)0(m)-287.8(from)-283.9(the)-293.8(measles)-278.9(patient,)-288.1(respectively;)]TJ 0 -0.9958 TD [(lane)-226.7(3,)-231.6(AM)-225(from)-227(the)-229.8(healthy)-222.8(individual.)-221.2(Both)-226.3(gels)-228.9(contained)-217.5(2%)-228.6(agarose)]TJ 0 -1.003 TD [(and)-220.3(were)-227(stained)-224(with)-226.5(ethidium)-217.3(bromide)-221.9(for)-228.8(visualiz)10.5(ation.)-226.9(Sizes)-223.6(of)-223.6(PCR-)]TJ T* [(amplificatio)8.8(n)-332.2(products)-327.4(are)-333.3(indicated.)]TJ 8.966 0 0 8.966 58.28 797.499 Tm (620)Tj 7.472 0 0 7.472 264.472 797.499 Tm 0.0001 Tc [(A.)-336.9(SHIMIZU)-340.1(E)0(T)-263.8(AL.)]TJ ET endstream endobj 21 0 obj << /ProcSet [/PDF /Text /ImageB ] /Font << /F4 7 0 R /F5 8 0 R /F8 11 0 R /F10 22 0 R /F11 23 0 R /F15 24 0 R >> /XObject << /Im1 15 0 R /Im2 16 0 R /Im3 17 0 R /Im4 18 0 R >> /ExtGState << /GS2 13 0 R /GS3 25 0 R /GS4 26 0 R >> >> endobj 28 0 obj << /Length 18035 >> stream BT /F4 1 Tf 9.963 0 0 9.963 58.28 771.647 Tm 0 g /GS2 gs 0 Tc [(of)-424.2(the)-420.5(predi)-8.2(cted)-421.7(size)-422.8(\(415)-425.8(base)-426.2(pairs)-424.8(\(bp\)\))-424(was)-423.2(readi)-8.6(ly)]TJ 0 -1.0471 TD [(demon)-7.4(strated)-508.8(in)-499(cDNA)-504.6(samp)-7.8(les)-501.3(from)-504.5(alveol)-10.1(ar)-498.6(macr)-8.6(o-)]TJ 0 -1.0528 TD [(phages)-325.2(and)-321.4(lym)-7.8(phocytes,)-323.8(but)-323.3(not)-323.3(from)-322.4(BAL)-322.3(supern)-7.8(atant)]TJ 0 -1.0471 TD [(or)-253.5(serum)-260.5(of)-253.5(the)-255.5(indi)-7.8(cated)-257.8(case)-255.8(\(fig)-8.6(.)-250.8(2a\).)-255.1(The)-257.2(meas)-8.2(les)-251(viral)]TJ 0 -1.0528 TD 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-1.0528 TD [(\(GAPD)-10.7(H\))-320(mess)-9(enger)-324.9(\(m\)RNA)-330.8(\(cDNA\))-327.2(was)-326.5(detected)-331.2(by)]TJ 0 -1.0471 TD [(PCR-a)-8.8(mplifi)-10.8(cation)-220.7(in)-220.2(all)-218(the)-215.6(RNA)-225.4(samples)-224.6(extra)-8.6(cted)-216.8(from)]TJ 0 -1.0527 TD [(lung)-181.8(ce)-8(lls)-179(of)-185.2(the)-181.5(indi)-7.8(cated)-183.8(case)-187.6(and)-184.8(the)-181.5(health)-10.1(y)-177.2(contr)-8.2(ol)-180.3(\(fig)-8.6(.)]TJ 0 -1.0471 TD [(2b\))-333.9([15].)]TJ /F7 1 Tf 9.1675 -3.9606 TD [(Discuss)-9.1(ion)]TJ /F4 1 Tf -8.1659 -2.3502 TD [(Th)17.1(is)-431.9(re)19.2(po)15.5(rt)-426.6(de)15.1(sc)19.6(ri)17.3(be)15.1(s)-434.4(a)0(n)-428.7(a)0(d)15.1(u)0(l)18.9(t)-441.3(ca)20.4(se)-429.9(of)-429.9(me)17.7(as)13.9(le)18.4(s)-440.1(p)0(n)21.2(e)0(u)15.1(-)]TJ -1.0015 -1.0528 TD 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[(cl)18.4(on)15.5(al)-277.5(an)20.8(ti)16.5(bo)15.5(di)18.9(es)-276.3(an)15.1(d)-285.3(b)0(y)-274.7(e)0(l)18.4(e)0(c)14.7(t)0(r)17.3(o)0(n)-274.7(m)0(i)15.7(c)0(r)19.2(o)0(s)14.4(c)0(o)20.8(p)0(i)18.9(c)-285.7(an)15.1(al)18.4(ys)14.4(i)13.9(s)-286.5([7)13.9(,)]TJ 0 -1.0471 TD [(19].)-402.6(Measl)-10.1(es)-401.5(virus)-401.6(tends)-406.1(to)-402.2(reside)-408.9(in)-402.2(giant)-401.6(cell)-8.6(s)-400.3(and)-401(in)]TJ 0 -1.0528 TD [(type)-364.3(II)-368.9(alveolar)-372.2(epithelium)-373.9(in)-362.4(the)-363.6(lung.)-370(It)-364(has)-362.4(also)-371.2(been)]TJ 0 -1.0471 TD [(isolated)-333.9(from)-333.8(peripheral)-335.5(blood)-330.6(lymphocy)-12(tes,)-325.3(monoc)-7.4(ytes,)]TJ 0 -1.0528 TD [(neutr)-8.2(ophils,)-301.1(plate)-9.4(lets)-299.6(and)-298.6(serum)-300.4(its)-8.2(elf)-296.9([20].)-302.5(Other)-302.3(report)-10.6(s)]TJ 0 -1.0471 TD [(have)-265.6(shown)-265(the)-266.8(measles)-270.5(virus)-265.1(genom)-7.4(e)-262.9(t)0(o)-260(b)0(e)-263.7(detectable)-272.9(in)]TJ 0 -1.0528 TD 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-1.0471 TD [(infec)-8.6(ted)-278.2(not)-272.1(only)-278.6(alveolar)-281.1(macr)-8.6(ophages)-280.5(but)-272.1(also)-280.2(lympho-)]TJ 0 -1.0528 TD [(cytes)-321.2(in)-311.2(the)-318.1(lung,)-313.1(even)-316.8(though)-319.9(the)-312.4(viral)-317.9(g)-6.5(enome)-315.1(was)-315.1(not)]TJ 0 -1.0471 TD [(found)-363.9(in)-356.7(serum)-363(in)-356.7(the)-357.9(init)-10.2(ial)-354.6(stage)-366.7(of)-355.9(pneum)-7.4(onia.)-359(How-)]TJ 0 -1.0527 TD [(eve)-8.8(r)31.8(,)-410.1(since)-417.9(it)-416(rema)-8.6(ins)-409.9(u)-6.5(nclear)-419.5(whether)-418.1(meas)-8.2(les)-416(virus)-413(is)]TJ T* [(norm)-7.8(ally)-247.2(absent)-248(in)-248.6(lung)-244.4(cells)-249.6(in)-242.9(healthy)-249.9(indi)-7.8(viduals,)-245.4(more)]TJ 0 -1.0471 TD [(detai)-9.4(led)-335.1(inves)-7.8(tigatio)-9.6(n)-330.8(may)-335.9(b)-6.5(e)-331.2(needed.)]TJ /F1 1 Tf 7.97 0 0 7.97 380.523 623.735 Tm [(Acknowled)11.4(gements.)]TJ /F4 1 Tf 9.0692 0 TD [(The)-962.8(authors)-955.4(thank)-951.1(A.)]TJ -10.0651 -1.1239 TD 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