TY - T1的血清sCD163 adip作为生物标志物ose tissue inflammation in obstructive sleep apnoea patients: limits and perspectives JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01182-2017 VL - 50 IS - 2 SP - 1701182 AU - Ryan, Silke Y1 - 2017/08/01 UR - //www.qdcxjkg.com/content/50/2/1701182.abstract N2 - I thank D. Monneret and J-P. Bastard for their interest in our manuscript [1] and I could not agree more with their comment that the role of soluble CD163 (sCD163) in obstructive sleep apnoea (OSA) requires further detailed evaluation. As outlined in our article, the measurement of sCD163 in our patient cohort followed our results from the in vitro and in vivo studies demonstrating M1 polarisation of adipose tissue macrophages in response to intermittent hypoxia and thus, was not an a priori hypothesis of our study. Nonetheless, the detected independent association of sCD163 with OSA severity is intriguing.sCD163 in sleep apnoea requires further evaluation http://ow.ly/o3R130d82YZ ER -