RT期刊文章SR电子T1吸入皮质类固醇和COPD中肺癌的风险：一项基于人群的队列研究JF欧洲呼吸杂志JO EUR RESSIR J FD欧洲呼吸学会SP 1801257 DO 10.1183/139993003.01257-2012-2018-2018 VO 53 IS 6 A A1 Raymakers，Raymakers，188bet官网地址亚当J.N.A1 SADATSAFAVI，MOHSEN A1 SIN，DON D.A1 FITZGERALD，J.MARK A1 MARRA，CARLO A.A1 LYND，LARRY D. YR 2019 UL //www.qdcxjkg.com/content.com/content/53/6/6/6/6/1801257.AbstractAB吸入的皮质类固醇（ICS）通常在患有慢性阻塞性肺疾病（COPD）的患者中处方。他们对COPD患者死亡的主要原因的影响仍然不确定。从1997年至2007年，加拿大不列颠哥伦比亚省的基于人口的链接行政数据仍不确定。COPD患者的癌症风险和ICS使用。根据≥50岁的受试者的三个与COPD相关的处方，定义了COPD。使用多种时间依赖的方法（“曾经”暴露，累积使用时间，累积剂量，加权累积使用时间和加权累积剂量），将接触IC的暴露纳入了多变量的COX回归模型。标准。队列的平均±SD年龄为70.7±11.1岁，女性为53％。 There were 994 (2.5%) cases of lung cancer during follow-up. In the reference case analysis (time-dependent “ever” exposure), ICS exposure was associated with a 30% reduced risk of lung cancer (HR 0.70 (95% CI 0.61–0.80)). ICS exposure was associated with a decrease in the risk of lung cancer diagnosis over all five methods of quantifying exposure.This population-based study suggests that ICS use reduces the risk of lung cancer in COPD patients.Inhaled corticosteroid use appears to reduce the risk of lung cancer in a population-based cohort of COPD patients http://ow.ly/UuDZ30o7Bdi