％0期刊文章％a工作，q％a schellekens，sl％a kroesbergen，a a hop，wc％a de jongste，jc％t对儿童中呼出的一氧化氮采样：呼吸急促的高原，气球和潮汐呼吸方法比较％d 1999％j欧洲呼吸期限％p 1406-1410％v 13％n 6％x本研究的目的是比较在受控慢呼气期间获得的呼出的一氧化氮浓度儿童容易执行的采样方法：将空气吹入气球中，并通过烟嘴呼吸。一百一百杆稳定，稳定的过敏性哮喘儿童（中位年龄11.7岁）重复执行以下任务：1）从总肺容量中呼气，通过对电阻器的电阻器，其标准化流量为20％的电阻率为20％每秒，使用生物反馈系统；2）单一的深呼气，呼气为不可损坏的聚酯薄膜气球；3）在2分钟内通过低阻力吹口呼吸。使用化学发光分析仪测量NO。29名儿童（29％）无法执行至少3 s的恒定呼气。所有儿童都毫不费力地进行了气球和潮汐呼吸方法。 NO concentrations (means +/-SEM) were 5.3+/-0.2 parts per billion (ppb) at the end-expiratory plateau, 5.2+/-0.3 ppb in balloons (intraclass correlation coefficient (r(i)) = 0.73) and 8.0+/-0.4 ppb during tidal breathing (p<0.001, r(i) = 0.53 compared to plateau values). Mean values of NO during tidal breathing increased significantly with time, suggesting increasing contamination with nasal air. It was concluded that, in asthmatic children, the end-expiratory plateau concentration of nitric oxide during exhalation at 20% of the vital capacity per second is similar to the values obtained with the balloon method, with satisfactory agreement, but differs from values obtained during tidal breathing. The balloon method is cheap, simple and offers the interesting possibility to study exhaled nitric oxide in young children independently of the presence of a nitric oxide analyser. %U //www.qdcxjkg.com/content/erj/13/6/1406.full.pdf