TY -的T1 -抑郁反应肺癌是普遍的,往往也是紧随其后的是一个贫穷的结果JF -欧洲呼吸杂志》乔和J SP - 173 LP - 178欧元六世- 11 - 1 AU Buccheri G Y1 - 1998/01/01 UR - //www.qdcxjkg.com/content/11/1/173.abstract N2 -在多种人类恶性肿瘤,包括肺癌、生活质量(QOL)影响患者的临床结局。然而,生活质量的许多方面都受到身体状况的影响。目前的研究是为了描述抑郁症的作用,抑郁症是一种不一定受身体因素影响的心理状态。所有新诊断为肺癌的患者都接受了ww.k. Zung提出的抑郁自评量表(SDS)。133名患者能够并愿意完成问卷。正如最初描述的那样,我们计算出了萧条指数。另外19个重要的预后变量被记录并可供评估。95例患者全部完成问卷20项,其中53例SDS指数及lt;or = 50(无抑郁),42例为中度或重度抑郁(SDS指数>50)。 The survival of depressed patients was significantly lower (p=0.048). Diverse SDS subscales were associated with survival, in either univariate or multivariate analysis. SDS item 19, "I feel that others would be better off if I were dead", emerged as the most significant one. A multivariate model of survival, constructed using only SDS data, had a global Chi-squared value of 29.78, and a p-value of 0.00023. Based on this evidence, it appears that a relationship does exist between patients' depression and prognosis, at least in lung cancer. Further studies are needed to clarify the prognostic effect of depression in more specific (and homogeneous) subgroups of patients. ER -