Ty-jour t1 - 肺和胸壁力学在正常的麻醉科目和患者中不同窥视水平的患者JF - 欧洲呼吸期刊JO - EUR RESPIR J SP - 2545 LP - 2552 VL - 10是 - 11 Au - Musch,GAu - Foti,G Au - Cereda,M Au - Pelosi,P Au - Poppi,D Au - Pesenti,A Y1 - 1997/11/01 UR - //www.qdcxjkg.com/content/10/11/2545.Abstract N2 - 为了评估肺部和胸壁对慢性阻塞性肺病(COPD)呼吸力学(COPD)急性通气衰竭患者(AVF)的呼吸力学紊乱的相对贡献,我们研究了八名接受受控机械的COPD患者AVF和九个正常受试者的通风,麻痹作为对照组的手术。随着中断技术的使用以及我们测量的食管球囊技术:静态肺和胸壁弹性(分别为E [ST,L]和E [ST,W]),最大(R [L,MAX]),最小(r [l,min])和另外的(δ[l])肺电阻,额外的胸壁抵抗(deltarw),在COPD组中,总固有阳性末端呼气压力(Peeptot)。在0,5,10和15cmH 2O的施加正末端呼气压力(PEEP)中重复测量。我们发现,在COPD组中:1)e(st,w)和deltarw高于正常组;2)由于R(L,MIN)和DELTARL增加,R(L,MAX)显着增加;3)甚至低水平的窥视增加了Peeptot; 4) PEEP did not reduce elastance or total resistance of either the lung or the chest wall. We conclude that chest wall mechanics are abnormal in chronic obstructive pulmonary disease patients with acute ventilatory failure undergoing controlled mechanical ventilation and that positive end-expiratory pressure does not seem to be effective in reducing either elastance or resistance of the lung or chest wall. ER -