TY - JOUR T1 -重度COPD住家鼻间歇正压通气:对肺功能和生活质量的影响JF -欧洲呼吸杂志JO - Eur Respir J SP - 2835 LP - 2839 DO - 10.1183/09031936.97.10122835 VL - 10 IS - 12 AU - Perrin, C AU - El Far, Y AU - Vandenbos, F AU - Tamisier, R AU - Dumon, MC AU - Lemoigne, F AU - Mouroux, J AU - Blaive，B Y1 - 1997/12/01 UR - //www.qdcxjkg.com/content/10/12/2835.abstract N2 -本研究的目的是确定住家式鼻间断正压通气(NIPPV)对高碳酸血症慢性阻塞性肺疾病(COPD)患者肺功能和生活质量的影响。14例临床状况稳定的高碳酸血症COPD患者在一项前瞻性研究中接受了住家NIPPV加长期氧疗。将4周磨合期获得的基线数据与6个月研究期结束时的测量结果进行比较。评估呼吸参数、动脉血气张力和生活质量。使用圣乔治呼吸问卷(SGRQ)和法语版诺丁汉健康概况(FVNHP)来测量生活质量。所有患者均完成6个月的住家NIPPV治疗。8例患者报告胃肠胀气。日间动脉氧张力及动脉二氧化碳张力治疗后改善。 During the NIPPV study period, the total SGRQ score and impacts score both improved significantly; significant improvements were also noted in the total FVNHP score and the physical mobility, emotional reactions, and energy component scores. Domiciliary nasal intermittent positive pressure ventilation combined with long-term oxygen therapy has been found to improve blood gases in spontaneous ventilation, as well as the quality of life of patients with chronic obstructive pulmonary disease. ER -