TY - T1的血液动力学的响应运动在慢性阻塞性肺疾病:评估阻抗图JF -欧洲呼吸杂志》乔欧元和J SP - 374 LP - 379 - 10.1183 / 09031936.98.12020374六世- 12 - 2非盟- HJ Bogaard AU - BM德克尔AU - BW亚琛AU - HH Woltjer AU - AR van Keimpema AU - PE Postmus盟- PM de Vries Y1 - 1998/08/01 UR - //www.qdcxjkg.com/content/12/2/374.abstract N2 -本研究旨在确定血液动力学的反应的差异之间的标准增量运动试验门诊病人与慢性阻塞性肺疾病(COPD)和年龄组和气流阻塞的严重程度之间的关系,发现在慢性阻塞性肺病和运动血液动力学。Twenty-two male patients with COPD (forced expiratory volume in one second (FEV1)/vital capacity (VC))<80% predicted) and 20 age-matched male controls performed an incremental exercise test (10 W x min(-1)) with ventilatory function and changes in stroke volume (deltaSV) and cardiac output (deltaCO) measured by means of electrical impedance cardiography (EIC). Submaximal deltaSV and deltaCO were lower in COPD patients. Peak exercise deltaSV were equal in patients and controls (128+/-33 versus 129+/-29%, p=0.98), whereas peak deltaCO was lower in patients (COPD versus controls: 232+/-71 versus 289+/-54%, p<0.005). In COPD patients, FEV1 (% pred) was significantly correlated to deltaSV at all submaximal exercise intensities, to peak exercise deltaSV and to peak exercise deltaCO. FEV1/VC (% pred) was significantly correlated to deltaSV at 30 and 60 W. In conclusion, in chronic obstructive pulmonary disease an aberrant haemodynamic response to exercise was found, especially in patients with severe airflow obstruction. This aberrant response is related to the degree of airflow obstruction and may limit exercise performance in patients with severe chronic obstructive pulmonary disease. ER -