TY - T1的特异反应性对稳定的哮喘和鼻炎患者呼出一氧化氮JF -欧洲呼吸杂志》乔欧元和J SP - 897 LP - 901 - 10.1034 / j.1399-3003.1999.14d28。x六世- 14 - 4 AU - C Gratziou AU - M Lignos AU - M Dassiou盟C·鲁索斯Y1 - 1999/10/01 UR - //www.qdcxjkg.com/content/14/4/897.abstract N2 -呼出的水平没有增加患者的过敏性哮喘和季节性鼻炎。本研究的目的是调查的意义特异反应性降低航空公司没有生产。测量呼出131年没有进行稳定的哮喘慢性轻度哮喘患者(95过敏性和36 nonatopics), 72例常年性鼻炎(57过敏性和15 nonatopics)和100年健康对照组(20过敏性和80 non-atopics)。Patients with either asthma or rhinitis had higher exhaled NO values (13.3+/-1.2 parts per billion (ppb) and 11.7+/-1.1 ppb) than control subjects (4.8+/-0.3 ppb, p<0.01). Exhaled NO levels were significantly higher in atopic asthmatics (19+/-3.6 ppb) compared with nonatopic patients (5.6+/-0.8 ppb, p<0.001). Similar findings were observed in patients with rhinitis (13.3+/-1.3 ppb in atopics and 5.8+/-1.2 ppb in nonatopics, p<0.001). No difference was found in NO levels between atopic and nonatopic control subjects (4.8+/-0.8 ppb, and 4.5+/-0.3 ppb). In summary, this study has shown that increased exhaled NO levels are detected only in atopic patients with asthma and/or rhinitis and not in nonatopic patients. These findings may suggest that it is rather the allergic nature of airways inflammation, which is mainly responsible for the higher NO production in the lower airways. ER -