% % 0期刊文章% H Sakakibara M通% K松下% M Hirata % Y Konishi % S Suetsugu % T的异常在非肥胖和肥胖的阻塞性睡眠呼吸暂停患者% D 1999% R 10.1183 / 09031936.99.13240399 % % P J欧洲呼吸杂志》403 - 410 V % 13% 2% N X这项工作的目的是全面评估的特点在日本阻塞性睡眠呼吸暂停(OSA)患者和阐明的变量和呼吸暂停的严重程度之间的关系。48人头测量法的测量变量在37岁的健康男性和114年男性阻塞性睡眠呼吸暂停综合症的病人,他们被分类到54个非肥胖(体重指数(BMI) < 27公斤x m (2), apnoea-hypopnoea指数(AHI) = 25.3 + / - -16.1事件x h(1))和60肥胖(体重指数>或= 27公斤x m (2), AHI = 45.6 + / - -28.0 h(1))事件组。诊断多导睡眠图进行了在所有的阻塞性睡眠呼吸暂停综合症患者和正常对照组的19。非肥胖阻塞性睡眠呼吸暂停综合症的病人显示几个人头测量法的缺陷与BMI-matched正常对照组:1)减少在颅面部p距离基地,上颌和下颌水平和减少骨咽宽度;2)扩大舌头舌头卷的伪劣转变;3)放大软腭;4)下级定位舌骨;5)减少上呼吸道宽度在4个不同的水平。更广泛和严重的软组织异常有一些缺陷在颅面骨结构被发现肥胖的阻塞性睡眠呼吸暂停综合症组。非肥胖的阻塞性睡眠呼吸暂停综合症集团逐步回归模型AHI与两个骨结构变量是重要的决定因素:前颅基线长度(s (n)和下颌长度(我去)。 Although the regression model retained only linear distance between anterior vertebra and hyoid bone (H-VL) as an explainable determinant for AHI in the obese OSA group, H-VL was significantly correlated with soft tissue measurements such as overall tongue area (Ton), inferior tongue area (Ton2) and pharyngeal airway length (PNS-V). In conclusion, Japanese obstructive sleep apnoea patients have a series of cephalometric abnormalities similar to those described in Caucasian patients, and that the aetiology of obstructive sleep apnoea in obese patients may be different from that in non-obese patients. In obese patients, upper airway soft tissue enlargement may play a more important role in the development of obstructive sleep apnoea, whereas in non-obese patients, bony structure discrepancies may be the dominant contributing factors for obstructive sleep apnoea. %U //www.qdcxjkg.com/content/erj/13/2/403.full.pdf