TY - JOUR T1 -健康儿童呼出空气中的过氧化氢:引用值JF -欧洲呼吸杂志》乔和J SP - 483 LP - 485欧元六世- 12 - 2非盟Jobsis问盟——Raatgeep HC盟——Schellekens SL AU - Hop, WC盟,何曼思PW AU - de Jongste JC Y1 - 1998/08/01 UR - //www.qdcxjkg.com/content/12/2/483.abstract N2 -过氧化氢(H2O2)含量的增加,患有炎症性肺部疾病(包括哮喘)的成人和儿童呼出的空气的冷凝物中已经描述了炎症的标志。然而，健康儿童呼出的冷凝空气中[H2O2]的正常范围尚未确定。因此，本研究的目的是确定健康学龄儿童呼出[H2O2]的参考范围。93名健康的不吸烟儿童(48名女性和45名男性，平均年龄10岁，范围8-13岁)，过敏、湿疹或呼吸系统疾病史阴性，肺功能正常。呼出的空气冷凝物被荧光法检查存在的H2O2。此外，研究人员还评估了[H2O2]在受试者内、在受试者之间的重现性以及[H2O2]在-20℃存储期间的稳定性。所有儿童呼出凝析空气中H2O2中值为0.13 microM, 2.5 ~ 97.5%的参考范围为<0.01 ~ 0.48 microM。男女间差异不显著。 There was no correlation between exhaled [H2O2] and age or lung function. Repeated [H2O2] measurements on 2 consecutive days showed satisfactory within-subject reproducibility and [H2O2] in stored samples remained stable for at least 1 month at -20 degrees C. In conclusion, this study provides reference data for exhaled hydrogen peroxide in a large group of healthy children. The observed levels were lower than those reported previously for healthy adults and were independent of age, sex and lung function. ER -