TY - JOUR T1 -年轻丹麦农村的状况:农业的影响会更加暴露,肺功能JF -欧洲呼吸杂志》乔和J SP - 31 LP - 37欧元六世- 13 - 1 AU Omland O盟——Sigsgaard T非盟- Hjort C AU - Pedersen AU -米勒先生Y1 - 1999/01/01 UR - //www.qdcxjkg.com/content/13/1/31.abstract N2 -本研究的目的是评估哮喘的患病率(自述)和与这个年轻农民肺功能和与哮喘相关的因素。210名农业学生和1691名男性学生，以及407名男性对照组接受了研究。每位受试者都接受了一次医学访谈;使用干楔形肺量计记录1秒用力呼气量(FEV1)和用力肺活量(FVC)。采用炎法测定组胺支气管反应性。使用吸入性过敏原进行皮肤点刺试验。不吸烟者的哮喘患病率(5.4 ~ 10.8%)低于吸烟者(11.3 ~ 21.0%)(p<0.05)。报告有哮喘症状的女性几乎是男性的两倍。性、吸烟和哮喘/过敏家族史与哮喘显著相关。 Controls had higher standardized FEV1 and FVC residuals than male students, both nonsmokers (0.21 and 0.24) versus (-0.06 and -0.05) and smokers (0.29 and 0.33) versus (-0.11 and 0.13) (p<0.032). Bronchial hyperresponsiveness, asthma, siblings with allergy and working with cattle (controls only) were significantly associated with reduced lung function. In conclusion, the prevalence of asthma was significantly related to smoking, female sex, family history of asthma and allergy. Whilst bronchial hyperresponsiveness was associated with reduced lung function and lung function was slightly reduced in the male farming students, there was no association found between occupational farming exposure and either lung symptoms or lung function. ER -