TY - T1的呼气和吸气胸部计算机断层扫描和肺功能测试吸烟者JF -欧洲呼吸杂志》乔和J SP - 252 LP - 256欧元六世- 13 - 2非盟- Kubo说,K盟,Eda年代盟——山本,H盟——藤本,K盟——Matsuzawa Y盟——Maruyama Y AU -长谷川,米非盟-宋,年代盟,酒井法子F Y1 - 1999/02/01 UR - //www.qdcxjkg.com/content/13/2/252.abstract N2 -本研究评估小气道功能障碍和肺气肿的吸烟者的肺实质破坏,使用胸部呼气高分辨率计算机断层扫描(HRCT)和肺功能测试(击球)。气性破坏的程度是由视觉分类评分(VS)和平均HRCT数字全过期/全灵感(E /我比)计算63年男性吸烟者男性不吸烟者(A组)和10。Brinkman吸烟指数(BI),定义为香烟x天(1)x岁,估计。六十三吸烟者由击球时被分为三组:B1组(n = 7),与正常击球;group B2 (n=21), with diffusing capacity of the lung for carbon monoxide (DL,CO) > or = 80% predicted, forced expiratory volume in one second (FEV1) < 80% pred and/or residual volume (RV) > 120% pred; and group B3 (n=35), with DL,CO < 80% pred, FEV1 < 80% pred and/or RV > 120% pred. Heavy smokers (BI > or = 600) (n=48) showed a significant increase in emphysema by both VS and E/I. E/I was significantly elevated in both group B2 (mean+/-SD 0.95+/-0.05) and B3 (0.96+/-0.06) compared with group B1 (0.89+/-0.03). VS could not differentiate group B2 (3.9+/-5.0) from B1 (1.1+/-1.6). These findings suggest that the expiration/inspiration ratio reflects hyperinflation and airway obstruction, regardless of the functional characteristics of emphysema, in cigarette smokers. ER -