TY - T1的受迫振动测量不影响上气道肌肉张力或睡在临床研究JF -欧洲呼吸杂志》乔和J SP - 335 LP - 339欧元六世——18 - 2非盟-十二月,jr盟——Farre r . AU - Rigau J . AU -乌里韦卷非盟- Navajas d . AU -蒙特塞拉特,N2 -通过使用强迫振荡技术(FOT)测量呼吸阻抗，可以很容易地评估睡眠呼吸暂停/低通气综合征(SAHS)的上气道阻塞。该方法被认为是诊断睡眠呼吸障碍和持续气道正压(CPAP)滴定的一个有用的临床工具。然而，以往的研究表明，高频压力振荡应用于上气道可能引起脑电图(EEG)或上气道肌肉功能的改变。在临床睡眠研究中检查了FOT测量对上气道肌张力和脑电图的影响。纳入7例中度SAHS患者(年龄:54±11岁;呼吸暂停/低呼吸指数:43±21事件·h−1;体重指数:30±2 kg·m−2)。分析有和无FOT应用时颏舌肌表面肌电活动(EMGgg)和脑电图信号(频率:5hz和30hz;稳定睡眠时的峰-峰压力振荡:1 cmH2O)。 Measurements were carried out in two different situations. Step 1: applying FOT during episodes of obstructive events or flow limitation; and step 2: during prolonged periods of normal breathing at optimal CPAP. The root mean square of EMGgg activity and fast Fourier analysis (alpha and delta bands) of the EEG signal were performed. The application of FOT did not increase EMGgg activity in any of the situations studied. In addition, no evidence of the effects on EEG was found: alpha/delta relationship: awake:0.70, baseline sleep:0.13, FOT(5 Hz):0.18, FOT(30 Hz):0.11. The presented results suggest that the use of forced oscillation technique over the ranges of frequency and amplitude proposed for clinical sleep studies does not induce changes in upper airway muscle activity and neurological variables in patients with sleep apnoea/hypopnoea syndrome. This study was supported by grants CICYT (SAF99-0001), DGESIC (PM98-0027) and SEPAR 1999. ER -