％0期刊文章％A Celli，B.R。％a halbert，R.J。％a Isonaka，S。％a schau，B。％t人口对气道阻塞的不同定义的影响％d 2003％r 10.1183/09031936.03.00075102％j欧洲呼吸期刊％p 268-273％p 268-273％v 22％v 22％n 2％x x目前，就诊断慢性阻塞性肺部疾病的标准尚无共识。这项研究评估了气道阻塞的不同定义对基于人群样本中障碍的估计患病率的影响。使用第三次全国健康和营养检查调查，使用以下标准定义了阻塞性气道疾病：1）自我报告的慢性支气管炎或肺气肿的诊断；2）在一秒钟（FEV1）/强制生命力（FVC）<0.70和FEV1 <80％的强迫呼气量（全球慢性阻塞性肺疾病（金）IIA）中；3）FEV1/FVC低于正常的下限；4）男性中的FEV1/FVC <88％PRED，女性<89％；5）FEV1/FVC <0.70（“固定比率”）。 Spirometry in this dataset did not include reversibility testing, making it impossible to distinguish reversible from irreversible obstruction. Rates in adults varied from 77 per 1,000 (self-report) to 168 per 1,000 (fixed ratio). For persons aged >50 yrs, the fixed ratio criteria produced the highest rate estimates. For all subgroups tested, the GOLD Stage II criteria produced lower estimates than other spirometry-based definitions. Different definitions of obstruction may produce prevalence estimates that vary by >200%. International opinion leaders should agree upon a clear definition of chronic obstructive pulmonary disease that can serve as a population-based measurement criterion as well as a guide to clinicians. This study was supported by Boehringer Ingelheim, GmbH. %U //www.qdcxjkg.com/content/erj/22/2/268.full.pdf