TY - T1的肺部表现男性Castleman病在艾滋病毒感染:一个临床、生物和放射性研究摩根富林明-欧洲呼吸杂志》乔欧元和J SP - 118 LP - 125 - 10.1183 / 09031936.05.00130304六世- 26 - 1 AU Guihot a . AU - Couderc L-J。盟,Agbalika f . AU - Galicier l . AU -西p . AU - Rivaud e . AU -谢勒,a . AU - Zucman d . AU - Katlama c . AU - Oksenhendler大肠Y1 - 2005/07/01 UR - //www.qdcxjkg.com/content/26/1/118.abstract N2 -本研究的目的是报告临床、放射学和支气管肺泡灌洗(BAL)发现艾滋病患者的肺部表现男性Castleman病(MCD)。这是一个12病理组织切片证实患者的回顾性研究。临床表现如下:呼吸困难12例(9),咳嗽(n = 10),双边陶瓷器皿(n = 10),连同高烧、萎靡,周围淋巴结病(n = 12),肝脾肿大(n = 10)。两个病人患上了急性呼吸窘迫综合症。胸片和ct扫描显示网状(n = 7)和/或结节状(n = 7)间隙模式,与纵隔淋巴结病(n = 9),和双边胸腔积液(n = 3)。在所有情况下都Fibreoptic内窥镜检查是正常的。拜尔(n = 6)分析显示肾小球内和/或淋巴球增多(n = 6),和人类疱疹病毒8型DNA检测在两两种情况。特定病原体的污渍和文化负面的。所有患者接受依托泊苷和/或长春花碱,改进后2 - 4天。 Relapses were frequent (50 attacks in 12 patients). Six patients developed a non-Hodgkin's lymphoma, and five died. In conclusion, the pulmonary manifestation of HIV-related multicentric Castleman's disease is an acute reticulo-nodular interstitial pneumonitis, associated with severe systemic symptoms and peripheral lymphadenopathy. In bronchoalveolar lavage fluid, cellularity is not specific and human herpesvirus-8 DNA is detected. The clinical course is specific due to a rapid onset and regression, frequent relapses and a high occurrence of non-Hodgkin's lymphoma. ER -