TY - T1的预测价值平衡细胞差异在间质性肺疾病的诊断JF -欧洲呼吸杂志》乔欧元和J SP - 1000 LP - 1006 - 10.1183 / 09031936.04.00101303六世- 24 - 6非盟- l·威尔克盟R.A. Jorres AU -美国Costabel盟h . Magnussen Y1 - 2004/12/01 UR - //www.qdcxjkg.com/content/24/6/1000.abstract N2 -当前作者旨在量化对于一个给定的可能性如何诊断支气管肺泡的变化与知识灌洗(BAL)细胞分化。作为初始估计(先验概率),最终诊断的频率被采取。根据贝叶斯的理论,通过对细胞差异的分类,可以推导出每种疾病的后验概率。对5组疑似BAL前诊断的患者中的3组进行了分析:间质性肺病(ILD;(n= 710),炎症性疾病(n=583),或类似ILD的肺肿瘤(n=455)。总体而言,在1971例患者中,18.3%患有结节病,7.7%患有普通间质性肺炎(UIP), 4.4%患有外源性过敏性肺泡炎(EAA), 19.0%患有肿瘤。在怀疑ILD的组中,当淋巴细胞数量为30-50%且粒细胞数量较低时,结节病的可能性从33.7增加到68.1%;当淋巴细胞数量增加30%,粒细胞增加时,UIP的可能性从15.8%增加到33.3%。CD4/CD8在结节病和EAA中具有重要意义。 Despite considerable increases, the likelihood of rare diseases rarely reached appreciable values. Similar results were obtained in the other two groups of suspected diagnoses. In conclusion, these data suggest that bronchoalveolar lavage cell counts per se provide substantial diagnostic information only in relatively frequent diseases, such as sarcoidosis and usual interstitial pneumonia, and are less helpful in infrequent diseases. This study was supported by Landesversicherungsanstalt (LVA), Freie und Hansestadt Hamburg, Germany. ER -