作者@article {Ishimoto253 = {H。Ishimoto h . Mukae和y日期和t . Shimbara m . s . Mondal j . Ashitani和t .冢久保和Kohno和m .基本上}title ={识别hBD-3呼吸道和血清:肺炎}的增加,体积={27}={2},页面= {253 - 260}= {2006},doi ={10.1183 / 09031936.06.00105904},出版商={欧洲呼吸学会},文摘={人类β-defensin (hBD) 3、45个氨基酸抗菌肽,原本孤立的从人体皮肤。188bet官网地址hBD-3信使rna中也发现了rt - pcr的航空公司。尽管hBD-3可能参与抗菌防御呼吸道内的存在hBD-3肽在呼吸系统尚未得到证实。合成的抗菌活性hBD-3肽是由径向扩散试验测量和菌落计数分析。目前作者确认hBD-3肽的存在在人类肺癌和血清的匀浆用反相高效液相色谱法加上一个高度敏感的RIA。的本地化hBD-3肽被免疫组织化学研究。此外,血清浓度hBD-3 RIA测定。hBD-3表现出很强的抗菌活性,增加盐浓度的影响。免疫组织化学,当前作者观察到的表达hBD-3支气管和细支气管上皮细胞。 The mean{\textpm}sd serum concentration of hBD-3 in patients with bacterial pneumonia was 239.4{\textpm}17.8 pg{\textperiodcentered}mL-1 in the acute phase and, decreased to 159.3{\textpm}20.1 pg{\textperiodcentered}mL-1 after the completion of therapy. In conclusion, these findings will help elucidate the role of human β-defensin-3 in host immune responses and identify the pathophysiological significance of this molecule in respiratory infections.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/27/2/253}, eprint = {//www.qdcxjkg.com/content/27/2/253.full.pdf}, journal = {European Respiratory Journal} }