ty -jour t1-房屋灰尘和儿童过敏敏化JF中的细菌和霉菌成分JF-欧洲呼吸杂志-Heinrich,J.Au -Hoek,G.Au -Giovannangelo,M.Au -Nordling,E.Au -Bellander,T。Au -Gerritsen,J.Au -de Jongste,J.C.Au -Smit,Smit,H。A. Au -Wichmann,Wichmann,Wichmann,Wichmann,他。Au -Wickman,M.Au -Brunekreef,B。Y1-2007/06/01Ur -http://www.qdcxjkg.com/content/content/29/6/1144.44.abstract n2-建议您早期的幼儿暴露微生物剂降低了儿童过敏的风险。目前的作者研究了2 - 4年年龄的儿童中尘埃中微生物剂与过敏敏化之间的关联。在德国,荷兰和瑞典正在进行的出生队列研究中进行了嵌套的病例对照研究,每个国家选择了约180名非敏化儿童的〜180个敏感性。细菌内毒素,β(1,3) - 葡萄糖和真菌细胞外多糖(EPS)的水平在儿童床垫和客厅地板的灰尘样品中测量。在各个国家之间,内毒素,β(1,3) - 葡萄糖和EPS的床垫灰尘和较高的床垫灰尘负荷与对吸入过敏原的敏感性大大降低有关。相互调整后,仅床垫灰尘量的保护作用保持显着(优势比(95%置信区间)0.57(0.39-0.84))。 Higher amounts of mattress dust may decrease the risk of allergic sensitisation to inhalant allergens. The effect might be partly attributable to endotoxin, β(1,3)-glucans and extracellular polysaccharides, but could also reflect (additional) protective effects of (microbial) agents other than the ones measured. It is not possible to distinguish with certainty which component relates to the effect, since their levels are highly correlated. ER -