@article {Schuurmans1090, author = {Schuurmans, M. M. and Ellmann, A. and Bouma, H. and Diacon, A. H. and Dyckmans, K. and Bolliger, C. T.}, title = {Solitary pulmonary nodule evaluation with 99mTc-methoxy isobutyl isonitrile in结核病 - 流行区域},体积= {30},number = {6},页面= {1090--1095},年= {2007},doi = {10.1183/09031936.00046107},188bet官网地址摘要= {结核病的高患病率增加了非恶性孤立肺结节(SPNS)的几率。使用18F-氟脱氧葡萄糖的正电子发射断层扫描(PET)是鉴定需要治愈手术的恶性SPN的首选方法。但是,宠物并不广泛。technetium-99m甲氧基异戊酸(MIBI)廉价,广泛使用,显示出恶性SPN的摄取增加。本研究的目的是前瞻性评估MIBI单光子发射计算机断层扫描的诊断值,以区分结核病 - 流行区域中的良性和恶性SPN。总共对49例放射学不确定的SPN(单个病变<= 6 cm的直径)患者进行了前瞻性评估。最终诊断是通过支气管镜检查,细针吸入,手术切除或临床随访> = 2年来确定的。在13个恶性病变中,共有12个(92 \%)显示了MIBI的摄取增加,而在36个良性病变中,33(92 \%)在33个(92 \%)中没有观察到摄取。 MIBI uptake indicated malignancy with a sensitivity and specificity of 92\% and a negative predictive value of 97\%. In this tuberculosis-endemic area, technetium-99m methoxy isobutyl isonitrile single photon emission computed tomography evaluation of solitary pulmonary nodules had a high negative predictive value. Therefore, it has the potential to prevent unnecessary surgical resections of benign nodules and serve as a low-cost alternative when positron emission tomography is not available.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/30/6/1090}, eprint = {//www.qdcxjkg.com/content/30/6/1090.full.pdf}, journal = {European Respiratory Journal} }