ty -jour t1- 99m tc-甲氧基异丁基等异构体JF -lim supir s jf-欧洲呼不VL -30 IS -6 Au -Schuurmans,M.M.Au -Ellmann,A.Au -Bouma -Bouma,H。Au -diacon,A。H. Au -au -diackmans,K。au -au -Bolliger,C。T. Y1 - 2007/2007/12/01 UR -HTTP:http:http:http://www.qdcxjkg.com/content/30/6/1090.abstract N2-结核病的高患病率增加了非恶性孤立肺结节(SPNS)的几率。使用18F-氟脱氧葡萄糖的正电子发射断层扫描(PET)是鉴定需要治愈手术的恶性SPN的首选方法。但是,宠物并不广泛。technetium-99m甲氧基异戊酸(MIBI)廉价,广泛使用,显示出恶性SPN的摄取增加。本研究的目的是前瞻性评估MIBI单光子发射计算机断层扫描的诊断值,以区分结核病 - 流行区域中的良性和恶性SPN。总共有49例放射学不确定的SPN(单个病变≤6cm的直径)患者被前瞻性评估。最终诊断是通过支气管镜检查,细针抽吸,手术切除或临床随访≥2岁的。在13个恶性病变中,共有12名(92%)显示了MIBI的摄取增加,而在36个良性病变中,有33个(92%)没有观察到摄取。 MIBI uptake indicated malignancy with a sensitivity and specificity of 92% and a negative predictive value of 97%. In this tuberculosis-endemic area, technetium-99m methoxy isobutyl isonitrile single photon emission computed tomography evaluation of solitary pulmonary nodules had a high negative predictive value. Therefore, it has the potential to prevent unnecessary surgical resections of benign nodules and serve as a low-cost alternative when positron emission tomography is not available. ER -