作者@article {Peetsold1140 = {M。g . Peetsold h·a·Heij和a . f . Nagelkerke h . IJsselstijn d . Tibboel和p h . Quanjer r . j . b . j . Gemke} title ={肺功能和运动能力的幸存者先天性膈疝},体积={34}={5},页面= {1140 - 1147}= {2009},doi ={10.1183/09031936.00181408},出版商={欧洲呼吸学会},文摘={先天性膈疝(CDH)与肺发育不全和肺动脉高压有关。188bet官网地址本研究的目的是评估肺功能和运动能力及其早期的决定因素在儿童和青少年天生高风险鼎晖(CDH-associated呼吸窘迫在第一个24小时)并探讨这些发现与鼎晖严重程度之间的关系。84年出生的159名患者和高危鼎晖幸存了下来。的69名符合条件的患者,53岁的孩子(意思是{\ textpm} sd年龄11.9 {\ textpm} 3.5岁)接受肺量测定法,肺容积测量和最大心肺运动试验(CPET)。肺功能测试的结果与健康对照组相比匹配性,年龄和身高。鼎晖幸存者的用力呼气量明显降低在1 s (FEV1)、用力肺活量(FVC)、FEV1 / FVC、最大mid-expiratory流量和最大呼气流量与健康对照组相比。残余体积/肺活量比率显著更高。线性回归分析表明,gastro-oesophageal返流性疾病是一个独立的行列式FEV1和FVC的减少。CPET在这些测试结果正常。 High-risk CDH survivors have mild to moderate pulmonary function abnormalities when compared with a healthy matched control group, which may be related to gastro-oesophageal reflux disease in early life. Exercise capacity and gas exchange parameters were normal in those tested, indicating that the majority of patients do not have physical impairment.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/34/5/1140}, eprint = {//www.qdcxjkg.com/content/34/5/1140.full.pdf}, journal = {European Respiratory Journal} }