TY - JOUR T1 -静脉血栓栓塞和COPD加重JF -欧洲呼吸杂志JO - Eur Respir J SP - 1243 LP - 1248 DO - 10.1183/09031936.00120909 VL - 35 IS - 6 AU - Gunen, H. AU - Gulbas, G. AU - In, E. AU - Yetkin, O. AU - Hacievliyagil，S. S. Y1 - 2010/06/01 UR - //www.qdcxjkg.com/content/35/6/1243.abstract N2 -本研究的目的是确定慢性阻塞性肺疾病(COPD)加重期静脉血栓栓塞(VTE)的患病率和危险因素。连续纳入因病情加重而住院的COPD患者。记录入院时的症状、体征和临床、血液学和流行病学参数。所有患者均行ct血管造影和超声检查深静脉血栓和肺栓塞(PE)。计算Wells和Geneva评分。随访患者1年，以确定死亡率。深静脉血栓形成14例，PE 18例。不明原因急性加重患者的VTE患病率比已知原因急性加重患者高3倍(p = 0.016)。VTE患者中，20例(95%)d -二聚体水平较高。 The negative predictive value of D-dimer testing was 0.98. Although the moderate- and high-risk categories of both the Wells and Geneva methods covered all PE patients, the Wells method identified 49% less potential patients for PE investigation. Mortality at 1 yr was higher (61.9% versus 31.8%) in VTE patients (p = 0.013). VTE is a common problem in COPD patients hospitalised with an exacerbation, leading to high long-term mortality. D-dimer levels and the Wells criteria can be used to determine whether or not these patients are assessed for a thromboembolic event. ER -