TY -的T1 -如何治疗儿童肺炎:a complex problem JF - European Respiratory Journal JO - Eur Respir J SP - 932 LP - 933 DO - 10.1183/09031936.00170809 VL - 35 IS - 4 AU - Don, M. AU - Korppi, M. Y1 - 2010/04/01 UR - //www.qdcxjkg.com/content/35/4/932.abstract N2 - To the Editors: We read with great interest the analysis of cost minimisation in the treatment of paediatric community-acquired pneumonia (CAP) by Lorgelly et al. 1 in the current issue of the European Respiratory Journal. The analysis was based on the randomised controlled non-blinded multicentre equivalence trial (PIVOT study), in which oral amoxicillin and intravenous benzyl penicillin had equivalent efficacy in the treatment of CAP in 246 children admitted to hospital 2. The median time for temperature to be <38°C for 24 h was 1.23 days in the intravenous penicillin group and 1.30 days in the oral amoxicillin group 2. The median in-patient stay was significantly shorter in the oral amoxicillin group than in the intravenous penicillin group (1.77 versus 2.10 days, respectively). The PIVOT study did not take into account the aetiology or severity of CAP, or the age of the patients. The high levels of nonspecific inflammation markers suggested that most patients had either bacterial or mixed viral–bacterial CAP. Children with complicated pneumonia, such as those with oxygen saturation … ER -