PT -期刊文章盟山姆,a . AU -桑切斯,D。AU - Gómez, V. AU - Wagner, C. AU - Kopecna, D. AU - Zamarro, C. AU - Moores, L. AU - Aujesky, D. AU - Yusen, R. AU - Jiménez Castro, D. TI - The shock index and the simplified PESI for identification of low-risk patients with acute pulmonary embolism AID - 10.1183/09031936.00070110 DP - 2011 Apr 01 TA - European Respiratory Journal PG - 762--766 VI - 37 IP - 4 4099 - //www.qdcxjkg.com/content/37/4/762.short 4100 - //www.qdcxjkg.com/content/37/4/762.full SO - Eur Respir J2011 Apr 01; 37 AB - We compared the test characteristics of the shock index (SI) and the simplified pulmonary embolism severity index (sPESI) for predicting 30-day outcomes in a cohort of 1,206 patients with objectively confirmed pulmonary embolism (PE). The primary outcome of the study was all-cause mortality. The secondary outcome was nonfatal symptomatic recurrent venous thromboembolism (VTE) or nonfatal major bleeding. Overall, 119 (9.9%) out of 1,206 patients died (95% CI 8.2–11.5%) during the first month of follow-up. The sPESI classified fewer patients as low-risk (369 (31%) out of 1,206 patients, 95% CI 28–33%) compared to the SI (1,024 (85%) out of 1,206 patients, 95% CI 83–87%) (p<0.001). Low-risk patients based on the sPESI had a lower 30-day mortality than those based on the SI (1.6% (95% CI 0.3–2.9%) versus 8.3% (95% CI 6.6–10.0%)), while the 30-day rate of nonfatal recurrent VTE or major bleeding was similar (2.2% (95%CI 0.7–3.6%) versus 3.3% (95%CI 2.2–4.4%)). The net reclassification improvement with the sPESI was 13.4% (p = 0.07). The integrated discrimination improvement was estimated as 1.8% (p<0.001). The sPESI quantified the prognosis of patients with PE better than the SI.