@article {MacNaughton231，作者= {MacNaughton，PD和Morgan，CJ和Denison，DM和Evans，TW}，Title = {测量通风受试者中碳一氧化碳转移和肺部体积，体积= {6}，数字= {6}，数字= {2}，第2页= {231--236}，年= {1993}，Publisher = {欧洲呼吸社会}，Ab188bet官网地址stract = {通过评估重新呼吸技术测量肺量和一氧化碳转移因子（TLCO）的简单方法在接受间歇性正压通气（IPPV）的九名健康志愿者中。在IPPV期间，将TLCO，牙槽体积（VA）和一氧化碳转移系数（KCO）的测量与三个启发的氧浓度（21、35和70 \％）进行了比较。还研究了10 CMH2O阳性呼气压力（PEEP）的影响。得出了肺毛细血管血容量（VC）和肺泡毛细血管膜（DM）的扩散能力。IPPV（TLCOIPPV）和自发呼吸（TLCOSV）期间TLCO的测量值之间存在密切相关性（r = 0.92）。通风的TLCO为自发呼吸TLCO的64 +/- 8％。KCO的通风和自发呼吸测量之间有着密切的一致性（r = 0.95;平均差异0.14，95 \％一致的限制+0.37至-0.09至-0.09 mmol.min.min-1 x xkpa-1 x x l-1）。自发呼吸期间的VC为92 +/- 23 mL，在IPPV期间为72 +/- 21毫升（P \ <0.05）。 PEEP of 10 cmH2O significantly increased functional residual capacity (2.3 +/- 0.5 to 3.5 +/- 0.6 l) and decreased TLCO (5.9 +/- 1.0 to 5.3 +/- 1.2 mmol.min-1 x kPa-1), KCO (1.7 +/- 0.2 to 1.1 +/- 0.3 mmol.min-1 x kPa-1 x l-1) and Vc (82 +/- 22 to 56 +/- 20 ml). Dm did not change with PEEP. This simple method may be a useful means of assessing gas exchange and lung volume in ventilated subjects. It showed that PEEP increased lung volume but reduced TLCO and that this reduction appeared to be due to a reduction in capillary blood volume.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/6/2/231}, eprint = {//www.qdcxjkg.com/content/6/2/231.full.pdf}, journal = {European Respiratory Journal} }