PT -期刊文章非盟关于PD非盟-摩根,CJ盟——丹尼森,DM AU -埃文斯,TW TI -测量一氧化碳的转移和肺容积通风学科DP - 1993年2月01 TA -欧洲呼吸杂志》第六PG - 231 - 236 - 6 IP - 2 4099 - //www.qdcxjkg.com/content/6/2/231.short 4100 - //www.qdcxjkg.com/content/6/2/231.full所以欧元和J1993 2月01;6 AB -一个简单的方法来测量肺容积和一氧化碳转移因子(TLCO)由一个换气技术评估在9个健康志愿者进行间歇正压通气(IPPV)。测量TLCO,肺泡体积(VA)和一氧化碳传递系数(KCO)在三个启发氧气浓度(21岁,35岁和70%)在IPPV相比获得在自主呼吸。10 cmH2O积极的影响结束呼气压力(偷看)也进行了研究。肺毛细血管血容量(Vc)和肺泡毛细血管膜的扩散能力(Dm)。之间有紧密的相关性测量期间TLCO IPPV (TLCOIPPV)和自主呼吸(TLCOSV) (r = 0.92)。通风TLCO是64 + / - 8%的自发呼吸TLCO。之间有一个紧密的协议KCO通风和自发呼吸测量(r = 0.95;平均差0.14,+ 0.37到-0.09更易与95%限制的协议。最低为1 x kPa-1 x l - 1)。Vc was 92 +/- 23 ml during spontaneous breathing and 72 +/- 21 ml during IPPV (p < 0.05). PEEP of 10 cmH2O significantly increased functional residual capacity (2.3 +/- 0.5 to 3.5 +/- 0.6 l) and decreased TLCO (5.9 +/- 1.0 to 5.3 +/- 1.2 mmol.min-1 x kPa-1), KCO (1.7 +/- 0.2 to 1.1 +/- 0.3 mmol.min-1 x kPa-1 x l-1) and Vc (82 +/- 22 to 56 +/- 20 ml). Dm did not change with PEEP. This simple method may be a useful means of assessing gas exchange and lung volume in ventilated subjects. It showed that PEEP increased lung volume but reduced TLCO and that this reduction appeared to be due to a reduction in capillary blood volume.