TY - JOUR T1 - hiv感染和其他免疫抑制患者卡氏肺孢子虫肺炎的临床特征和预后JF -欧洲呼吸杂志JO - Eur Respir J SP - 1548 LP - 1553 DO - 10.1183/09031936.95.08091548 VL - 8 IS - 9 AU - Ewig, S AU - Bauer, T AU - Schneider, C AU - Pickenhain, A AU - Pizzulli, L AU - Loos, U AU - Luderitz，B Y1 - 1995/09/01 UR - //www.qdcxjkg.com/content/8/9/1548.abstract N2 -不同高危人群卡氏肺孢子虫肺炎(PCP)死亡率差异的原因尚不清楚。因此，在这项回顾性研究中，我们比较了人类免疫缺陷病毒感染(HIV)患者和其他免疫抑制患者在没有预防措施的情况下首次发生PCP的情况。共分析了58例hiv感染患者和16例其他免疫抑制患者。比较包括流行病学、临床、实验室、放射学和微生物学数据，以及治疗和临床过程。采用logistic回归模型进行预后分析。两组的死亡率有显著差异(HIV组为17，非HIV组为50%)。肾移植患者的生存率高于恶性肿瘤或胶原血管疾病作为潜在危险疾病。急性呼吸衰竭在非hiv组更常见。在单因素分析中发现，与死亡结局显著相关的变量是肺泡-动脉氧压差(P(A-a)，O2)， hiv组的血红蛋白，血小板计数，总蛋白，血清白蛋白和γ -球蛋白，非hiv组的血清白蛋白。 In the multivariate analysis of the HIV group, platelet count and gamma-globulins remained independent prognostic factors. In conclusion, in the HIV-group, mortality is closely related to the severeness of PCP as well as to the severeness of the acquired immune deficiency syndrome (AIDS) disease. In the non-HIV group, malignancy and collagen vascular disease as underlying conditions at risk account for the high mortality rate. Its severeness was mainly reflected by serum albumin, which represented the only variable found to be significantly associated with death in both groups. ER -