RT期刊文章SR电子T1耐药结核的规划管理指南:2011更新摩根富林明欧洲呼吸杂志乔和J FD欧洲呼吸学会SP 516欧元OP 528做10.1183/09031936.00073611 VO 38 A1是3 d Falzon A1大肠Jaramillo A1 H.J. Schunemann A1 m . Arentz A1 m·鲍尔A1 J . Bay188bet官网地址ona A1 C.L.戴利A1 c·l·布兰科的A1 J.A. Caminero A1 Duncombe A1 c Fitzpatrick A1。吉哈德A1 h . Getahun A1 m . Henkens A1 T.H.霍尔兹A1 j . Keravec A1 s Keshavjee A1 A.J.汗A1 r . Kulier A1 V。陆Leimane A1 c Lienhardt A1 c A1。Mariandyshev A1 G.B. Migliori A1 F。Mirzayev A1 C.D.米特尼克A1 p·纳恩A1 g . Nwagboniwe A1 o . Oxlade A1 d Palmero A1 p Pavlinac A1 M.I. Quelapio A1贝拉Raviglione A1马丁丰富A1美国罗伊斯A1 s Rusch-Gerdes A1。Salakaia A1 r·萨林A1 d Sculier A1 F。Varaine A1 m .维多利亚A1 J.L. Walson A1 F。商品A1 K。韦A1 R.A.白色A1 m . Zignol年2011 UL //www.qdcxjkg.com/content/38/3/516.abstract AB的生产指导方针管理耐药结核病(TB)符合世界卫生组织(世卫组织)的授权来支持国家的病人护理的强化。谁委托外部评审总结证据优先病例发现问题,为耐多药结核病(mdr - TB)治疗方案,监测应对耐多药结核病治疗和保健的模型。 A multidisciplinary expert panel used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to develop recommendations. The recommendations support the wider use of rapid drug susceptibility testing for isoniazid and rifampicin or rifampicin alone using molecular techniques. Monitoring by sputum culture is important for early detection of failure during treatment. Regimens lasting ≥20 months and containing pyrazinamide, a fluoroquinolone, a second-line injectable drug, ethionamide (or prothionamide), and either cycloserine or p-aminosalicylic acid are recommended. The guidelines promote the early use of antiretroviral agents for TB patients with HIV on second-line drug regimens. Systems that primarily employ ambulatory models of care are recommended over others based mainly on hospitalisation. Scientific and medical associations should promote the recommendations among practitioners and public health decision makers involved in MDR-TB care. Controlled trials are needed to improve the quality of existing evidence, particularly on the optimal composition and duration of MDR-TB treatment regimens.