文摘
鼻间歇正压通气(NIPPV)已广泛应用于治疗慢性呼吸道疾病。呼吸器可能体积或预设的压力;每个类型都有理论优势,但到目前为止还没有正式的比较。我们想在血气变化,评估疗效可能实现,总体可接受性四个鼻呼吸器(两个预设压力:Respironics上下两层的正压通气(BiPAP)和托马斯刺骨的;和两个卷预设:BromptonPac和Monnal-D)稳定的慢性呼吸衰竭患者。平均年龄是59岁(范围48 - 71岁),意味着(SD)动脉氧张力(PaO2) 7.16 (0.21) kPa,动脉二氧化碳张力(PaCO2) 7.02 (0.35) kPa,在一秒用力呼气量(FEV1) 0.76(0.24),并用力肺活量(FVC) 1.58 (0.49) l。所有先前NIPPV使用。有重大改变血液气体与每个呼吸机:2 h意味着改变(95%置信区间);BiPAP PaO2 + 1.52 (0.95 - -2.09) kPa, paco2 - 1.04 kPa (1.55 - -0.54);凛冽的PaO2 + 1.63 (0.85 - -2.41) kPa, PaCO2, -1.1 kPa (1.86 - -0.34);BromptonPac PaO2 + 1.22 (0.75 - -1.67) kPa, PaCO2 -1.14 kPa (1.52 - -0.76); Monnal-D PaO2 +1.14 (0.42-1.84) kPa, PaCO2 -1.19 (2.14-0.23) kPa. Analysis of variance showed no significant differences in the efficacy of volume or pressure preset equipment, and all ventilators proved equally acceptable to the patients studied. We conclude that all four of the volume or pressure preset ventilators examined are suitable for the delivery of nasal intermittent positive pressure ventilation in patients with stable chronic respiratory failure.