文摘

目的:测试之间的重要联系空气污染和紧急住院循环系统疾病(国际分类diseases-9 390 - 459)在伦敦,英格兰,将符合污染的因果效应。方法:长期并行的趋势,温度、湿度、天的星期,1989年流行性感冒和周期性的共变周期> 20天在日常污染和招生指标1987 - 94年被允许。结果:有373556招生。没有发现协会O3和循环系统疾病之间的关系。四其他污染物与急性心肌梗塞和循环系统疾病的总和。P值和由病例(95%置信区间)对急性心肌梗死:黑烟P = 0.003, 2.5%(0.8%对4.3%);NO2 P = 0.002, 2.7%(0.8%对4.6%);有限公司P = 0.001, 2.1%(0.7%对3.5%);和二氧化硫P = 0.0006, 1.7%(0.7%对2.6%)。也有黑烟之间的关联和心绞痛(P = 0.02), NO2和心律失常(P = 0.04),公司和其他循环系统疾病(P = 0.004),但与心力衰竭。 Acute myocardial infarction was the only diagnosis for which there were significant associations with and without adjustment for cyclical terms. The associations with acute myocardial infarction were significant only in the cool season. CONCLUSION: Population data were consistent with 1 in 50 heart attacks currently presenting at London hospitals being triggered by outdoor air pollution. Further research is now needed to investigate whether background concentrations of black smoke, NO2, CO, and SO2 are a preventable cause of myocardial infarction. These results, if applied to all myocardial infarctions in the United Kingdom, indicate a potential saving of 6000 heart attacks a year.