条文本
摘要
背景—最大吸气压力(最大吸气压力)比最大吸气压力(最大吸气压力)更能反映吸气肌力。通过测量嗅探鼻吸气压(SNIP),可以无创地估计嗅探POES。目的是建立SNIP的最大正常值,并将其与PImax进行比较。方法:招募了160名20-80岁的健康受试者(80名男性)。所有受试者的用力肺活量(FVC)为>的80%,1秒用力呼气量(FEV1)/FVC为>的85%预测值,体重指数为18-31 kg/m2。因为已知在仰卧位时PImax会降低,所以在坐姿和仰卧位时都测量了SNIP。在四次动作中,通过使用标准法兰吹口的坐姿测量持续超过一秒的pmax。在坐位和仰卧位的FRC上测量SNIP,使用导管通过堵塞一个鼻孔,在对侧鼻孔进行10次最大嗅探。每次测试都考虑测量的最大压力,单位为cm H2O。结果:男性和女性的最大SNIP与年龄呈负相关,且在坐姿和仰卧位上相似。 In the sitting position maximal SNIP was greater or equal to PImax in 107 of 160 subjects. The mean (SD) ratio SNIP/PImax was 1.08 (0.22) in men and 1.17 (0.29) in women. CONCLUSIONS--Normal values of maximal SNIP can be predicted from age and sex. Maximal SNIP is similar in the sitting and the supine position and is significantly higher than PImax in healthy subjects. The low level of agreement between maximal SNIP and PImax indicates that the two manoeuvres are not interchangeable but complementary.